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The map label for this gene is tlpA [H]

Identifier: 75674913

GI number: 75674913

Start: 798045

End: 798716

Strand: Direct

Name: tlpA [H]

Synonym: Nwi_0716

Alternate gene names: 75674913

Gene position: 798045-798716 (Clockwise)

Preceding gene: 75674908

Following gene: 75674914

Centisome position: 23.46

GC content: 62.65

Gene sequence:

>672_bases
ATGACCGATACCCCTACGCCGCCTCATCGCGCCGAAAGCAGGTTTCCCATAGGCCCGCTGGTCGCAGTCGCCATTGTCGT
GGGGGCCACGGTGGCGCTTCTGGGAATCGGGCATCTCAGGCACGCGAAATCCGCCGTTAATGCGCTGGCGCCCTGCGGTC
CGGCCATGGAACTGTCCAGGAAGCTCGCCCCGCAGGCCACGGGCGAGGTGGCCTCCCTGACCATGGCGTCGAAGCCGCGT
CGGATGCCTGACCTGGCCTTTCTGGATGGCGAGGGCCAACCCATGAAGCTCTCGGACTGGAAGGGGAAAACCGTTCTCCT
GAACCTCTGGGCGACATGGTGTGTGCCTTGCAGAACCGAAATGCCGGCTCTGGACCGGCTTCAGGGCAAGCTCGGCGGCG
ATAAGTTCGCCGTGGTCGCCATCAATATCGACACCCGCGACTCCGATAAGCCGAAGGCTTTCCTGAAAGACGCCAACCTG
ACTCACCTCGGCAATTTCCATGACGAGAAGGCGTCCGTTTTCCAGGAGCTTAAAAGCGTTGGCATGGCGGTCGGCATGCC
GACCTCGGTGCTGATCGACGGCCAGGGTTGCGAACTCGGCAATATGGCCGGACCGGCTGAATGGGACAGCGAAGACGCCA
TCAAGCTGATCAACGCGGCGGTGGGCTCCTAA

Upstream 100 bases:

>100_bases
CACTTTCATCATGCCTGCCGGACGGCCGATCCGCTCCGGTGGGTGTAGCCGTCGAAGCCGACGCCTGCATACCCGTATCT
GATACAGGATGACAAACGTT

Downstream 100 bases:

>100_bases
AGCGCTTTCCGGCGGAGCGGATGACCTGTTCGCACGAACAGAACACGTCAGAACAGCGATCCGGAGCCTTGCTTCTGATT
CAATCAGAAGCCAGGCTGCT

Product: thioredoxin-like protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTDTPTPPHRAESRFPIGPLVAVAIVVGATVALLGIGHLRHAKSAVNALAPCGPAMELSRKLAPQATGEVASLTMASKPR
RMPDLAFLDGEGQPMKLSDWKGKTVLLNLWATWCVPCRTEMPALDRLQGKLGGDKFAVVAINIDTRDSDKPKAFLKDANL
THLGNFHDEKASVFQELKSVGMAVGMPTSVLIDGQGCELGNMAGPAEWDSEDAIKLINAAVGS

Sequences:

>Translated_223_residues
MTDTPTPPHRAESRFPIGPLVAVAIVVGATVALLGIGHLRHAKSAVNALAPCGPAMELSRKLAPQATGEVASLTMASKPR
RMPDLAFLDGEGQPMKLSDWKGKTVLLNLWATWCVPCRTEMPALDRLQGKLGGDKFAVVAINIDTRDSDKPKAFLKDANL
THLGNFHDEKASVFQELKSVGMAVGMPTSVLIDGQGCELGNMAGPAEWDSEDAIKLINAAVGS
>Mature_222_residues
TDTPTPPHRAESRFPIGPLVAVAIVVGATVALLGIGHLRHAKSAVNALAPCGPAMELSRKLAPQATGEVASLTMASKPRR
MPDLAFLDGEGQPMKLSDWKGKTVLLNLWATWCVPCRTEMPALDRLQGKLGGDKFAVVAINIDTRDSDKPKAFLKDANLT
HLGNFHDEKASVFQELKSVGMAVGMPTSVLIDGQGCELGNMAGPAEWDSEDAIKLINAAVGS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 23618; Mature: 23486

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTPTPPHRAESRFPIGPLVAVAIVVGATVALLGIGHLRHAKSAVNALAPCGPAMELSR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLAPQATGEVASLTMASKPRRMPDLAFLDGEGQPMKLSDWKGKTVLLNLWATWCVPCRTE
HHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEEHHHHHCCCCCC
MPALDRLQGKLGGDKFAVVAINIDTRDSDKPKAFLKDANLTHLGNFHDEKASVFQELKSV
CCHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GMAVGMPTSVLIDGQGCELGNMAGPAEWDSEDAIKLINAAVGS
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TDTPTPPHRAESRFPIGPLVAVAIVVGATVALLGIGHLRHAKSAVNALAPCGPAMELSR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KLAPQATGEVASLTMASKPRRMPDLAFLDGEGQPMKLSDWKGKTVLLNLWATWCVPCRTE
HHCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEECCCCCCEEEEEEHHHHHCCCCCC
MPALDRLQGKLGGDKFAVVAINIDTRDSDKPKAFLKDANLTHLGNFHDEKASVFQELKSV
CCHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GMAVGMPTSVLIDGQGCELGNMAGPAEWDSEDAIKLINAAVGS
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]