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The map label for this gene is metX [H]

Identifier: 75674783

GI number: 75674783

Start: 660098

End: 661297

Strand: Direct

Name: metX [H]

Synonym: Nwi_0585

Alternate gene names: 75674783

Gene position: 660098-661297 (Clockwise)

Preceding gene: 75674779

Following gene: 75674784

Centisome position: 19.4

GC content: 63.83

Gene sequence:

>1200_bases
ATGGTGAAAGTGCAATCGATATCGGGCCCGGCTCACCCCGAGCATCGTGCCCAGGAAGCAGACCATCCTACCTCGCAGGT
CGCGACGTTCGATACCGATCAACCGCTCCCGCTCGATTGCGGCGTCGATCTCGCGCCGTTCCAGATCGCCTACCAGACCT
ATGGCAAGCTCAATCCCGCGAAATCCAACGCCATCCTGATCTGCCATGCCCTCACCGGGGATCAGCATGTGGCCAACCCT
CACCCGGTGACCGGAAAACCCGGCTGGTGGGTGACGCTGGTGGGGCCCGGCAAGCCGCTCGACACCAGCAGGTACTTCAT
TATCTGCTCCAACGTGATCGGTGGCTGCATGGGCTCGACCGGCCCCGCCTCGACCAATCCCGAGACCGGCAGGGTGTGGG
GTCTGGACTTTCCCGTCATCACCATTCCCGACATGGTGCGCGCGCAGGCCATGCTGATCGACCGCCTGGGAATCGACACG
CTGTTTTCGGTGGTCGGCGGCTCGATGGGCGGCATGCAGGTGCTGCAGTGGTGCGTGGCCTATCCAAAGCGGGTGTTTTC
AGCGCTGCCGATCGCCTGCAGCACGCGCCACTCCGCGCAGAACATCGCGTTTCATGAACTGGGGCGGCAAGCGGTGATGG
CCGATCCCGATTGGCGCGAGGGCCGTTATGTCGAGCAGGGCACCCATCCCCGCCGGGGTCTTGGCGTGGCGCGGATGGCC
GCGCACATTACTTACCTGTCGGACGCGGCGCTGCATCGCAAGTTCGGGCGGCGGATGCAGGACCGCGAGCTGCCGACGTT
CTCGTTCGATGCGGATTTCCAGGTGGAGAGCTATCTGCGCCACCAGGGATCGTCATTCGTCGAGCGCTTCGACGCCAACA
GCTATCTCTATCTGACGCGGGCGATGGACTATTTCGATATCGCTGCCGATCATGACGGCGTGCTGGCCGCCGCGTTTCGC
GGGACCCGCACCCGGTTCTGCGTGGTTTCGTTCACGAGCGACTGGTTGTTTCCGACCGCCGAATCGCGGGCGACCGTGCA
TGCGCTCAATGCCGGCGGCGCGCGGGTCTCCTTCGCCGAGATCGAGACCGATCGCGGCCATGACGCCTTCCTGCTTGACG
TTCCCGAGTTCTTCGATATCGCGCATGCGTTTCTGGAATCGGCTGGAAAAACCCGTGGCCTGGCCGATGCGGAACGATGA

Upstream 100 bases:

>100_bases
AGCGAAATCCTGATCCCGGCCGAACCCAAGTTCGGGCCGGGTTTTTTGTGGCCTGCGATCCGGGGGCTTCCCGCAGCCTC
CGGCGGAGGTCAGCGGCAGG

Downstream 100 bases:

>100_bases
GATGAGCGCGGAGCAGCCGTCCCTGCCGTTGGATGAGGTCGCTTCGCGGCCGGTCGACCGCTATCGCAGCGATCACCTCC
TGTTGGCGGAGATGATCGAG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MVKVQSISGPAHPEHRAQEADHPTSQVATFDTDQPLPLDCGVDLAPFQIAYQTYGKLNPAKSNAILICHALTGDQHVANP
HPVTGKPGWWVTLVGPGKPLDTSRYFIICSNVIGGCMGSTGPASTNPETGRVWGLDFPVITIPDMVRAQAMLIDRLGIDT
LFSVVGGSMGGMQVLQWCVAYPKRVFSALPIACSTRHSAQNIAFHELGRQAVMADPDWREGRYVEQGTHPRRGLGVARMA
AHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRHQGSSFVERFDANSYLYLTRAMDYFDIAADHDGVLAAAFR
GTRTRFCVVSFTSDWLFPTAESRATVHALNAGGARVSFAEIETDRGHDAFLLDVPEFFDIAHAFLESAGKTRGLADAER

Sequences:

>Translated_399_residues
MVKVQSISGPAHPEHRAQEADHPTSQVATFDTDQPLPLDCGVDLAPFQIAYQTYGKLNPAKSNAILICHALTGDQHVANP
HPVTGKPGWWVTLVGPGKPLDTSRYFIICSNVIGGCMGSTGPASTNPETGRVWGLDFPVITIPDMVRAQAMLIDRLGIDT
LFSVVGGSMGGMQVLQWCVAYPKRVFSALPIACSTRHSAQNIAFHELGRQAVMADPDWREGRYVEQGTHPRRGLGVARMA
AHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRHQGSSFVERFDANSYLYLTRAMDYFDIAADHDGVLAAAFR
GTRTRFCVVSFTSDWLFPTAESRATVHALNAGGARVSFAEIETDRGHDAFLLDVPEFFDIAHAFLESAGKTRGLADAER
>Mature_399_residues
MVKVQSISGPAHPEHRAQEADHPTSQVATFDTDQPLPLDCGVDLAPFQIAYQTYGKLNPAKSNAILICHALTGDQHVANP
HPVTGKPGWWVTLVGPGKPLDTSRYFIICSNVIGGCMGSTGPASTNPETGRVWGLDFPVITIPDMVRAQAMLIDRLGIDT
LFSVVGGSMGGMQVLQWCVAYPKRVFSALPIACSTRHSAQNIAFHELGRQAVMADPDWREGRYVEQGTHPRRGLGVARMA
AHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRHQGSSFVERFDANSYLYLTRAMDYFDIAADHDGVLAAAFR
GTRTRFCVVSFTSDWLFPTAESRATVHALNAGGARVSFAEIETDRGHDAFLLDVPEFFDIAHAFLESAGKTRGLADAER

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=225, Percent_Identity=42.6666666666667, Blast_Score=175, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 43815; Mature: 43815

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVQSISGPAHPEHRAQEADHPTSQVATFDTDQPLPLDCGVDLAPFQIAYQTYGKLNPA
CEEEECCCCCCCCHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
KSNAILICHALTGDQHVANPHPVTGKPGWWVTLVGPGKPLDTSRYFIICSNVIGGCMGST
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHCCCCC
GPASTNPETGRVWGLDFPVITIPDMVRAQAMLIDRLGIDTLFSVVGGSMGGMQVLQWCVA
CCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHH
YPKRVFSALPIACSTRHSAQNIAFHELGRQAVMADPDWREGRYVEQGTHPRRGLGVARMA
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
AHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRHQGSSFVERFDANSYLYLTR
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHCCHHHHHHHCCCCEEEEEE
AMDYFDIAADHDGVLAAAFRGTRTRFCVVSFTSDWLFPTAESRATVHALNAGGARVSFAE
CCCHHEECCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEE
IETDRGHDAFLLDVPEFFDIAHAFLESAGKTRGLADAER
EECCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVKVQSISGPAHPEHRAQEADHPTSQVATFDTDQPLPLDCGVDLAPFQIAYQTYGKLNPA
CEEEECCCCCCCCHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
KSNAILICHALTGDQHVANPHPVTGKPGWWVTLVGPGKPLDTSRYFIICSNVIGGCMGST
CCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHCCCCC
GPASTNPETGRVWGLDFPVITIPDMVRAQAMLIDRLGIDTLFSVVGGSMGGMQVLQWCVA
CCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHH
YPKRVFSALPIACSTRHSAQNIAFHELGRQAVMADPDWREGRYVEQGTHPRRGLGVARMA
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
AHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRHQGSSFVERFDANSYLYLTR
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHCCHHHHHHHCCCCEEEEEE
AMDYFDIAADHDGVLAAAFRGTRTRFCVVSFTSDWLFPTAESRATVHALNAGGARVSFAE
CCCHHEECCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEE
IETDRGHDAFLLDVPEFFDIAHAFLESAGKTRGLADAER
EECCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA