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The map label for this gene is ogt [C]

Identifier: 75674770

GI number: 75674770

Start: 646926

End: 647153

Strand: Direct

Name: ogt [C]

Synonym: Nwi_0572

Alternate gene names: 75674770

Gene position: 646926-647153 (Clockwise)

Preceding gene: 75674769

Following gene: 75674771

Centisome position: 19.02

GC content: 64.91

Gene sequence:

>228_bases
ATGACCTATGGCGACATCGCCAAACGCCTTGGCGGCGTTGAGCTGTCGCGCGATGTCGGTCAGGCGCTCGGCCGTAATCC
GTGTCCGATCGTGGTGCCGTGCCATCGCGTGCTTGCCGCCGGCGACAGGCCGGGAGGTTTCTCGGCGAGCGACGGCGTCA
CGACCAAGCTGAGAATGCTCGCCATCGAGGGCGCGATCGTCAATCACACGCCGGGCCTTTTCGATTGA

Upstream 100 bases:

>100_bases
CCGATCGATTTATCCGGTGTGGTGCTCGCTCTCGACAGCGTAGGCGAATTCGATCGCCGCGTTTACGACATCGCACGGAC
CATTCCGCCAAGGCAGCACG

Downstream 100 bases:

>100_bases
CCTGTTTCGCGCAAAGAGCGGCTCCGGTCTGAAACCCGGCGGTCACGCCGTCCGCCGATGCCTCATTGCCGCCGCCGTGG
TAGGATGCTGTTTGGCGGCG

Product: methylated-DNA-(protein)-cysteine S-methyltransferase

Products: DNA; protein S-methyl-L-cysteine

Alternate protein names: Methylated-DNA/Protein-Cysteine Methyltransferase; Methylated-DNA-Protein-Cystein Methyltransferase; Methylated-DNA-[Protein]-Cysteine S-Methyltransferase; Methylated-DNA/Protein-Cysteinemethyltransferase; Methylated-DNA-(Protein)-Cysteine S-Methyltransferase; O-6-Methylguanine-DNA-Alkyltransferase; Methylated-DNAProtein-Cysteine Methyltransferase; Methylated-DNA-Protein-Cysteine

Number of amino acids: Translated: 75; Mature: 74

Protein sequence:

>75_residues
MTYGDIAKRLGGVELSRDVGQALGRNPCPIVVPCHRVLAAGDRPGGFSASDGVTTKLRMLAIEGAIVNHTPGLFD

Sequences:

>Translated_75_residues
MTYGDIAKRLGGVELSRDVGQALGRNPCPIVVPCHRVLAAGDRPGGFSASDGVTTKLRMLAIEGAIVNHTPGLFD
>Mature_74_residues
TYGDIAKRLGGVELSRDVGQALGRNPCPIVVPCHRVLAAGDRPGGFSASDGVTTKLRMLAIEGAIVNHTPGLFD

Specific function: Involved In The Cellular Defense Against The Biological Effects Of O6-Methylguanine (O6-Meg) In DNA. Repairs Alkylated Guanine In DNA By Stoichiometrically Transferring The Alkyl Group At The O-6 Position To A Cysteine Residue In The Enzyme. This Is A Sui

COG id: COG0350

COG function: function code L; Methylated DNA-protein cysteine methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.63

Molecular weight: Translated: 7817; Mature: 7686

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00374 MGMT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYGDIAKRLGGVELSRDVGQALGRNPCPIVVPCHRVLAAGDRPGGFSASDGVTTKLRML
CCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHEEE
AIEGAIVNHTPGLFD
HCCCEEECCCCCCCC
>Mature Secondary Structure 
TYGDIAKRLGGVELSRDVGQALGRNPCPIVVPCHRVLAAGDRPGGFSASDGVTTKLRML
CHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCHHHEEE
AIEGAIVNHTPGLFD
HCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA containing 6-O-methylguanine; protein L-cysteine

Specific reaction: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA