Click here to switch to the map view.

The map label for this gene is aer [H]

Identifier: 75674728

GI number: 75674728

Start: 589867

End: 591576

Strand: Direct

Name: aer [H]

Synonym: Nwi_0530

Alternate gene names: 75674728

Gene position: 589867-591576 (Clockwise)

Preceding gene: 75674725

Following gene: 75674729

Centisome position: 17.34

GC content: 62.05

Gene sequence:

>1710_bases
TTGGCGAGTTTTCCCGTGCGCAAGAACTTTCCGGTTACCGACGAAGAGTATCCCGTTTCCGATGACACGCTGATCGTTTC
CCGGACCGATCTCAAGGGGCGTCTCACCTATGTCAACGAAGACTTCATTGACGCCGCGGAGTTCACCTCCGAGGAACTGA
TAGGCAAGGCGCATAACATTGTCCGCCACCCGGACATGCCGCCGGAGGCGTTCGAGAATCTCTGGGACACCTTGAAGGCC
GAGAAACCATGGGTCGGCGCCATCAAGAACCGCCGCAAGAACGGCGGCTTTTACTGGGTGCTGGCAACGGCCTCGCCGAT
CCGGACGGACGGGCAGGTCACCGGCTATACCTCGATCCGCACCAGGCTTGCCGCCGACCAGCGCGCCCTCGCGGAAGACG
TGTATGCGGCCATTCGCGAAAAGCGCCCCCATCCGTATCGGATCGACGCCGGCATTATCAGGAAGCGATCGGTCTTTGAT
CGTTTCGGACTATTTACCCGTACCATGCGGGCGCGAATGACAACGCTGATCACCGTGCAGGCTGCTTTTCTGCTAGCTTG
CGGCTTGCTGGGCGCAGCCGTCATCGGCGGCATATGGGGCCTCGCCCTCATCCTTCTCGCCGCCGCCGGGATCGCCGTCG
GGGGAATGGTGGGACGTCAGACCCTGCGTGCGTTCGAGGGACCGATGCGTCACCTGAACGAAACGATGCTGAACCTCGTT
CACGACAAATTCGACAATCGGATCGAAATCAGGCGCGACGACGAGATCGGCGAAGCCCTCCGCAACCTCCAGACCGTGCA
GACGCTTATTCGTTTCAGCCGGGAAGAGGTCAACTCCACGCAACGCCGGGCCGACGCCCAGCGCAAGATCGACATGACAA
AGATCGCCAATTCCTTCGAGGCGGCCATCGGCGAGATTGTTCAGGCTGTCGCGACATCGGCGACCGAACTGGAGGCTTCG
GCATCGACGCTGGCCTCGAACGCCGATCATGCAAAGGATTTTGCGGCACGCGTCGCCAACGGTTCGACCGAAGCCTCCTC
CAACGTCAATTCGGTGGCCTCGGCCACGGAGGAGATGACCGCCTCGGTCCGTGAAATCAGCCAGCGCGTGCAGGAATCAG
CGCGCATGGCGGGCGAGGCCGTCGATCAGGTGCATTCGGCGACCGAGCGCGTCAGCGCGTTGTCGAGCGCGGCGGCTCGC
ATCGGCGATATTGTCGAGATGATCAACAATATCGCGGGACAGACCAATCTTCTCGCCCTGAACGCCACCATCGAGGCGGC
GCGCGCCGGCGAAGCCGGTCGCGGATTTTCAGTCGTCGCCTCGGAAGTCAAGGCGCTCGCCGAGCAAACCGGCAAGGCCA
CCGGCGAAATCGGTCAGCAGATCAGCGGCATCCAGTCCGCCACGCATGAATCCGTCGCCGCGATCAATGAGATCCGGAAC
TCCATCGAAAAGCTTTCCGGCATCTCCTCCACGATCGCGTCAGCCATCGAAGAACAGGGGGCGACGACGCAGGAAGTTGC
CCGCAACGTGCAGCACGCAGCCCAGGGTGCGCAGGAAGTGTCCTCGAACGTCGGCAATCTCCAGCGCGGGGCGGTGGAGA
CCGGGAATGCCTCATCTTTGGTGTTGTCTGCCGCGCAGACGCTGTCGCGCGATAGCGCCAGGCTCAAGACGGAGGTCGAC
AATTTCCTGAACTCCGTCCGGGTTGCATGA

Upstream 100 bases:

>100_bases
AGCTTTTGAGGGTATCGGTACCGATTTCCGCTGACGCGGTTCCTCGCGAATCGCGTCATGACAGCACATCGGTCGTGACG
CTTGCTTTCACCATAACAGA

Downstream 100 bases:

>100_bases
AGCATTGATAGAGGACGATCCGGGAAGAGCGCAGGCGACAGCGTTGTCGAATGAAGCATGTCCTTAAGCTTGACCTGACT
CGCGTGAGGAAAACGCGTCC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MASFPVRKNFPVTDEEYPVSDDTLIVSRTDLKGRLTYVNEDFIDAAEFTSEELIGKAHNIVRHPDMPPEAFENLWDTLKA
EKPWVGAIKNRRKNGGFYWVLATASPIRTDGQVTGYTSIRTRLAADQRALAEDVYAAIREKRPHPYRIDAGIIRKRSVFD
RFGLFTRTMRARMTTLITVQAAFLLACGLLGAAVIGGIWGLALILLAAAGIAVGGMVGRQTLRAFEGPMRHLNETMLNLV
HDKFDNRIEIRRDDEIGEALRNLQTVQTLIRFSREEVNSTQRRADAQRKIDMTKIANSFEAAIGEIVQAVATSATELEAS
ASTLASNADHAKDFAARVANGSTEASSNVNSVASATEEMTASVREISQRVQESARMAGEAVDQVHSATERVSALSSAAAR
IGDIVEMINNIAGQTNLLALNATIEAARAGEAGRGFSVVASEVKALAEQTGKATGEIGQQISGIQSATHESVAAINEIRN
SIEKLSGISSTIASAIEEQGATTQEVARNVQHAAQGAQEVSSNVGNLQRGAVETGNASSLVLSAAQTLSRDSARLKTEVD
NFLNSVRVA

Sequences:

>Translated_569_residues
MASFPVRKNFPVTDEEYPVSDDTLIVSRTDLKGRLTYVNEDFIDAAEFTSEELIGKAHNIVRHPDMPPEAFENLWDTLKA
EKPWVGAIKNRRKNGGFYWVLATASPIRTDGQVTGYTSIRTRLAADQRALAEDVYAAIREKRPHPYRIDAGIIRKRSVFD
RFGLFTRTMRARMTTLITVQAAFLLACGLLGAAVIGGIWGLALILLAAAGIAVGGMVGRQTLRAFEGPMRHLNETMLNLV
HDKFDNRIEIRRDDEIGEALRNLQTVQTLIRFSREEVNSTQRRADAQRKIDMTKIANSFEAAIGEIVQAVATSATELEAS
ASTLASNADHAKDFAARVANGSTEASSNVNSVASATEEMTASVREISQRVQESARMAGEAVDQVHSATERVSALSSAAAR
IGDIVEMINNIAGQTNLLALNATIEAARAGEAGRGFSVVASEVKALAEQTGKATGEIGQQISGIQSATHESVAAINEIRN
SIEKLSGISSTIASAIEEQGATTQEVARNVQHAAQGAQEVSSNVGNLQRGAVETGNASSLVLSAAQTLSRDSARLKTEVD
NFLNSVRVA
>Mature_568_residues
ASFPVRKNFPVTDEEYPVSDDTLIVSRTDLKGRLTYVNEDFIDAAEFTSEELIGKAHNIVRHPDMPPEAFENLWDTLKAE
KPWVGAIKNRRKNGGFYWVLATASPIRTDGQVTGYTSIRTRLAADQRALAEDVYAAIREKRPHPYRIDAGIIRKRSVFDR
FGLFTRTMRARMTTLITVQAAFLLACGLLGAAVIGGIWGLALILLAAAGIAVGGMVGRQTLRAFEGPMRHLNETMLNLVH
DKFDNRIEIRRDDEIGEALRNLQTVQTLIRFSREEVNSTQRRADAQRKIDMTKIANSFEAAIGEIVQAVATSATELEASA
STLASNADHAKDFAARVANGSTEASSNVNSVASATEEMTASVREISQRVQESARMAGEAVDQVHSATERVSALSSAAARI
GDIVEMINNIAGQTNLLALNATIEAARAGEAGRGFSVVASEVKALAEQTGKATGEIGQQISGIQSATHESVAAINEIRNS
IEKLSGISSTIASAIEEQGATTQEVARNVQHAAQGAQEVSSNVGNLQRGAVETGNASSLVLSAAQTLSRDSARLKTEVDN
FLNSVRVA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=541, Percent_Identity=29.3900184842884, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1787690, Length=272, Percent_Identity=30.8823529411765, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=226, Percent_Identity=32.7433628318584, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788194, Length=186, Percent_Identity=36.0215053763441, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI2367378, Length=221, Percent_Identity=31.6742081447964, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 61247; Mature: 61115

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFPVRKNFPVTDEEYPVSDDTLIVSRTDLKGRLTYVNEDFIDAAEFTSEELIGKAHNI
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
VRHPDMPPEAFENLWDTLKAEKPWVGAIKNRRKNGGFYWVLATASPIRTDGQVTGYTSIR
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
TRLAADQRALAEDVYAAIREKRPHPYRIDAGIIRKRSVFDRFGLFTRTMRARMTTLITVQ
HHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLLACGLLGAAVIGGIWGLALILLAAAGIAVGGMVGRQTLRAFEGPMRHLNETMLNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDKFDNRIEIRRDDEIGEALRNLQTVQTLIRFSREEVNSTQRRADAQRKIDMTKIANSFE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIGEIVQAVATSATELEASASTLASNADHAKDFAARVANGSTEASSNVNSVASATEEMT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHH
ASVREISQRVQESARMAGEAVDQVHSATERVSALSSAAARIGDIVEMINNIAGQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NATIEAARAGEAGRGFSVVASEVKALAEQTGKATGEIGQQISGIQSATHESVAAINEIRN
ECHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIEKLSGISSTIASAIEEQGATTQEVARNVQHAAQGAQEVSSNVGNLQRGAVETGNASSL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHH
VLSAAQTLSRDSARLKTEVDNFLNSVRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASFPVRKNFPVTDEEYPVSDDTLIVSRTDLKGRLTYVNEDFIDAAEFTSEELIGKAHNI
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
VRHPDMPPEAFENLWDTLKAEKPWVGAIKNRRKNGGFYWVLATASPIRTDGQVTGYTSIR
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
TRLAADQRALAEDVYAAIREKRPHPYRIDAGIIRKRSVFDRFGLFTRTMRARMTTLITVQ
HHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLLACGLLGAAVIGGIWGLALILLAAAGIAVGGMVGRQTLRAFEGPMRHLNETMLNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDKFDNRIEIRRDDEIGEALRNLQTVQTLIRFSREEVNSTQRRADAQRKIDMTKIANSFE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIGEIVQAVATSATELEASASTLASNADHAKDFAARVANGSTEASSNVNSVASATEEMT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHH
ASVREISQRVQESARMAGEAVDQVHSATERVSALSSAAARIGDIVEMINNIAGQTNLLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NATIEAARAGEAGRGFSVVASEVKALAEQTGKATGEIGQQISGIQSATHESVAAINEIRN
ECHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIEKLSGISSTIASAIEEQGATTQEVARNVQHAAQGAQEVSSNVGNLQRGAVETGNASSL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHH
VLSAAQTLSRDSARLKTEVDNFLNSVRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]