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The map label for this gene is atpA [H]

Identifier: 75674628

GI number: 75674628

Start: 484989

End: 486521

Strand: Direct

Name: atpA [H]

Synonym: Nwi_0430

Alternate gene names: 75674628

Gene position: 484989-486521 (Clockwise)

Preceding gene: 229125527

Following gene: 75674629

Centisome position: 14.26

GC content: 63.93

Gene sequence:

>1533_bases
ATGGACATCCGCGCCGCGGAAATTTCGGCGATCCTGAAGGATCAGATCAAGAATTTCGGCAAGGAAGCCGAAGTTTCGGA
AGTCGGACAGGTGCTGTCCGTCGGCGACGGTATCGCCCGCGTCTATGGCCTTGACAACATCCAGGCCGGCGAGATGGTCG
AGTTCGAGAACGGTACGCGCGGCATGGCGCTGAACCTCGAAACCGACAACGTCGGTATCGTGATTTTCGGCGCCGACCGC
GAGATCAAGGAAGGCCAGACCGTCAAGCGCACCCGCGCCATCGTCGACGCGCCGGTCGGCAAGGGCCTGCTCGGCCGCGT
GGTCGACGCGTTGGGCAATCCGATCGACGGCAAGGGGCCGATCCAGGGCGCCGAGCGCAAGCGCGTTGACGTCAAGGCGC
CCGGCATCATTCCGCGCAAGTCGGTGCATGAGCCGATGGCGACCGGCCTCAAGGCCATCGACGCCCTGATCCCGATCGGC
CGCGGGCAGCGCGAATTGATCATCGGCGACCGCCAGACCGGCAAAACCGCGATCGCGCTCGACACCATTCTCAATCAGAA
GCCGCTCAACGTCGCCGGCGCCCCGGAGAGCCAGAAGCTCTATTGCGTCTATGTCGCGGTCGGCCAGAAGCGCTCCACCG
TGGCGCAGTTCGTCAAGGTGCTCGAGGAGCAGGGCGCGCTGGAATATTCGATCGTGGTCGCCGCGACCGCGTCCGATCCG
GCCCCGATGCAGTACCTAGCGCCCTTCACCGGCTGCACCATGGGCGAATACTTCCGCGACAACGCCATGCACGCCGTCAT
CATTTATGACGACCTTTCCAAGCAGGCCGTCGCCTATCGTCAGATGTCGCTTCTGCTGCGTCGCCCGCCGGGCCGCGAGG
CCTATCCGGGCGACGTGTTCTACTTGCATTCCCGCCTTCTGGAGCGCGCCGCCAAGCTGAATGACAGCCAGGGCAACGGC
TCGCTGACCGCGCTGCCGGTGATCGAGACCCAGGCCAACGACGTGTCGGCCTACATTCCGACCAACGTGATTTCGATCAC
CGACGGCCAGATCTTCCTCGAAACCGACCTGTTCTTCCAGGGCATCCGCCCCGCGGTGAACGTCGGCCTTTCGGTGTCGC
GCGTCGGCTCCTCGGCGCAGACCAAGGCGATGAAGAAGGTCGCCGGCAAGATCAAGGGCGAACTCGCGCAGTACCGCGAA
ATGGCGGCCTTCGCGCAGTTCGGCTCCGATCTCGACGCCTCGACCCAGCGACTGCTCAACCGCGGTTCGCGCCTGACCGA
GCTTCTCAAGCAGCCGCAGTTCTCGCCGCTGAAGATGGAAGAGCAGGTGGTGGTGATCTGGGCCGGCACCAATGGCTATC
TTGATCCGCTGCCGCTCGGCAAGGTGCGTGCGTTCGAGGATGGGCTGTTGTCGCTGTTGCGCGGCCAACATGCCGACATC
CTTAACACCATCCGCGACACCCGTGATCTCAGCGACGAGACGGCGGGCAAGCTCAAGAGCATCGTCGAAGGTTACGCCAA
GACGTTTGCGTAA

Upstream 100 bases:

>100_bases
TCATCGGCGGGCTTGTCGTCAAGCTCGGCAGTCGCATGGTGGACACCTCGCTCCGGACCAAACTCAATTCGATCAAGCAC
GCGATGAAAGAGGCAGGCTG

Downstream 100 bases:

>100_bases
GTTTTCGTCGTGTCCGCGCCATGAGGCGCGGGGACGAAAGACGACGTGGATGCCCGGCACAAGACCGGGCGTGGCGAAGT
AGGGAATTTGCGGCCGGGTC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNIQAGEMVEFENGTRGMALNLETDNVGIVIFGADR
EIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGPIQGAERKRVDVKAPGIIPRKSVHEPMATGLKAIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYLAPFTGCTMGEYFRDNAMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGSRLTELLKQPQFSPLKMEEQVVVIWAGTNGYLDPLPLGKVRAFEDGLLSLLRGQHADI
LNTIRDTRDLSDETAGKLKSIVEGYAKTFA

Sequences:

>Translated_510_residues
MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNIQAGEMVEFENGTRGMALNLETDNVGIVIFGADR
EIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGPIQGAERKRVDVKAPGIIPRKSVHEPMATGLKAIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYLAPFTGCTMGEYFRDNAMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGSRLTELLKQPQFSPLKMEEQVVVIWAGTNGYLDPLPLGKVRAFEDGLLSLLRGQHADI
LNTIRDTRDLSDETAGKLKSIVEGYAKTFA
>Mature_510_residues
MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNIQAGEMVEFENGTRGMALNLETDNVGIVIFGADR
EIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGPIQGAERKRVDVKAPGIIPRKSVHEPMATGLKAIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
APMQYLAPFTGCTMGEYFRDNAMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDASTQRLLNRGSRLTELLKQPQFSPLKMEEQVVVIWAGTNGYLDPLPLGKVRAFEDGLLSLLRGQHADI
LNTIRDTRDLSDETAGKLKSIVEGYAKTFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=70.4365079365079, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=70.4365079365079, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=307, Percent_Identity=29.3159609120521, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=316, Percent_Identity=28.4810126582279, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI32189394, Length=383, Percent_Identity=25.065274151436, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI19913424, Length=249, Percent_Identity=25.7028112449799, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790172, Length=519, Percent_Identity=54.9132947976879, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1790170, Length=406, Percent_Identity=25.1231527093596, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788251, Length=341, Percent_Identity=26.3929618768328, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=70.4365079365079, Blast_Score=726, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=70.4365079365079, Blast_Score=724, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=65.2777777777778, Blast_Score=659, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=331, Percent_Identity=27.7945619335347, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=304, Percent_Identity=28.6184210526316, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=56.578947368421, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=394, Percent_Identity=24.1116751269036, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=263, Percent_Identity=25.0950570342205, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=70.1789264413519, Blast_Score=727, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=349, Percent_Identity=30.6590257879656, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=380, Percent_Identity=25.2631578947368, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=69.3675889328063, Blast_Score=714, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=309, Percent_Identity=29.7734627831715, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646341, Length=309, Percent_Identity=29.7734627831715, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136796, Length=309, Percent_Identity=29.7734627831715, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28574560, Length=428, Percent_Identity=25.7009345794392, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638766, Length=383, Percent_Identity=25.065274151436, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583988, Length=249, Percent_Identity=24.8995983935743, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583986, Length=249, Percent_Identity=24.8995983935743, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583984, Length=249, Percent_Identity=24.8995983935743, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583992, Length=249, Percent_Identity=24.8995983935743, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55183; Mature: 55183

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNIQAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEECCCCC
GMALNLETDNVGIVIFGADREIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
IQGAERKRVDVKAPGIIPRKSVHEPMATGLKAIDALIPIGRGQRELIIGDRQTGKTAIAL
CCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
HHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYLAPFTGCTMGEYFRDNAMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCHHHHCCCCCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDSQGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGSRLTELLKQPQFSPLKMEEQVVVIWAGTNGYLDPLPLGKVRAFEDGLLSLLRGQHADI
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LNTIRDTRDLSDETAGKLKSIVEGYAKTFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNIQAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEECCCCC
GMALNLETDNVGIVIFGADREIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
IQGAERKRVDVKAPGIIPRKSVHEPMATGLKAIDALIPIGRGQRELIIGDRQTGKTAIAL
CCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDP
HHHHCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYLAPFTGCTMGEYFRDNAMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCHHHHCCCCCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDSQGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGSRLTELLKQPQFSPLKMEEQVVVIWAGTNGYLDPLPLGKVRAFEDGLLSLLRGQHADI
CCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LNTIRDTRDLSDETAGKLKSIVEGYAKTFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA