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The map label for this gene is qseB [H]

Identifier: 74318809

GI number: 74318809

Start: 2871834

End: 2872499

Strand: Direct

Name: qseB [H]

Synonym: Tbd_2791

Alternate gene names: 74318809

Gene position: 2871834-2872499 (Clockwise)

Preceding gene: 74318804

Following gene: 74318810

Centisome position: 98.69

GC content: 70.12

Gene sequence:

>666_bases
ATGCGGGTATTGCTGATCGAAGACGACGACCTGATCGCCCACGGTGTCCAGGCTGGCCTGGGCGCGCGGGGCCTGACGGT
GGATCGGGTCGAGACCGCGGCGCAGGCGCGAACCATGCTCGCGACCGTGCACTACCAACTGGCGATTCTCGATCTCGGTC
TGCCCGACGAGGATGGCATGAGTCTGCTGCAGCGCTGGCGCGCGGCGGGCGTCGATCTGCCGGTGCTGGTGCTGACCGCG
CGCGACGCCGTGGAGGACCGGGTCGCCGGACTGCGCGCCGGCGCGGACGATTACCTGCTCAAACCCTTCGACCTCGACGA
ACTGCTCGCCCGCCTGCAGGCGCTGCTGCGCCGCGCCGCCGGGCGCAGCGCGGATGTCGTCGAGCATGGCGCGCTGCGGC
TCGACCTCGAGCGCGGTGACGTCTCTCTCAACGGCCGTCCCGTCGTGCTGACGCGGCGCGAGCTGGCGCTGCTGGCCGCG
CTGCTGCACGCGCGCGGCCGCATCCTCAGCGCCGACCAGCTCAAGGACAGCCTGTACGGGTTCAGCGAGGAGATCGAGAG
CAACGCACTGAGCGTGCATATCCACCACCTGCGGCGCAAGCTCGGCGCCGACCTGATCGAGACCGTGCGCGGCCTCGGCT
ACCGCTTCAACATGTCAGACGCATGA

Upstream 100 bases:

>100_bases
AGCATGAACAGCTCCAAAATCTTGACGAGCGCGCATCTTTGACGGCCCGGGTTAAGGCTACATTAACGGAGCTGTGCGAC
GAACGTAGGGGCACCACTTT

Downstream 100 bases:

>100_bases
GCCTGCGCCTGCGTCTGCTGCTGATGATCGGGGTGTCGCTGAGCCTGTTGTGGGGCGGGGTCGCGATGTGGATGCTGCAC
GATCTGGAAGGTGAAATGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRVLLIEDDDLIAHGVQAGLGARGLTVDRVETAAQARTMLATVHYQLAILDLGLPDEDGMSLLQRWRAAGVDLPVLVLTA
RDAVEDRVAGLRAGADDYLLKPFDLDELLARLQALLRRAAGRSADVVEHGALRLDLERGDVSLNGRPVVLTRRELALLAA
LLHARGRILSADQLKDSLYGFSEEIESNALSVHIHHLRRKLGADLIETVRGLGYRFNMSDA

Sequences:

>Translated_221_residues
MRVLLIEDDDLIAHGVQAGLGARGLTVDRVETAAQARTMLATVHYQLAILDLGLPDEDGMSLLQRWRAAGVDLPVLVLTA
RDAVEDRVAGLRAGADDYLLKPFDLDELLARLQALLRRAAGRSADVVEHGALRLDLERGDVSLNGRPVVLTRRELALLAA
LLHARGRILSADQLKDSLYGFSEEIESNALSVHIHHLRRKLGADLIETVRGLGYRFNMSDA
>Mature_221_residues
MRVLLIEDDDLIAHGVQAGLGARGLTVDRVETAAQARTMLATVHYQLAILDLGLPDEDGMSLLQRWRAAGVDLPVLVLTA
RDAVEDRVAGLRAGADDYLLKPFDLDELLARLQALLRRAAGRSADVVEHGALRLDLERGDVSLNGRPVVLTRRELALLAA
LLHARGRILSADQLKDSLYGFSEEIESNALSVHIHHLRRKLGADLIETVRGLGYRFNMSDA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=214, Percent_Identity=49.0654205607477, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1790552, Length=214, Percent_Identity=44.8598130841121, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=41.8918918918919, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=38.1818181818182, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=35.3711790393013, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=34.3612334801762, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=37.9464285714286, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=38.5650224215247, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.5291479820628, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=30.9417040358744, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=32.7433628318584, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.1929824561404, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=35.6521739130435, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24192; Mature: 24192

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDDLIAHGVQAGLGARGLTVDRVETAAQARTMLATVHYQLAILDLGLPDEDGM
CEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
SLLQRWRAAGVDLPVLVLTARDAVEDRVAGLRAGADDYLLKPFDLDELLARLQALLRRAA
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRSADVVEHGALRLDLERGDVSLNGRPVVLTRRELALLAALLHARGRILSADQLKDSLYG
CCCCCHHHCCCEEEEEECCCEEECCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
FSEEIESNALSVHIHHLRRKLGADLIETVRGLGYRFNMSDA
HHHHHCCCHHEEHHHHHHHHHCHHHHHHHHHCCEEECCCCC
>Mature Secondary Structure
MRVLLIEDDDLIAHGVQAGLGARGLTVDRVETAAQARTMLATVHYQLAILDLGLPDEDGM
CEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHH
SLLQRWRAAGVDLPVLVLTARDAVEDRVAGLRAGADDYLLKPFDLDELLARLQALLRRAA
HHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHC
GRSADVVEHGALRLDLERGDVSLNGRPVVLTRRELALLAALLHARGRILSADQLKDSLYG
CCCCCHHHCCCEEEEEECCCEEECCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
FSEEIESNALSVHIHHLRRKLGADLIETVRGLGYRFNMSDA
HHHHHCCCHHEEHHHHHHHHHCHHHHHHHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]