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The map label for this gene is lpxP [H]

Identifier: 74318540

GI number: 74318540

Start: 2594194

End: 2595057

Strand: Direct

Name: lpxP [H]

Synonym: Tbd_2522

Alternate gene names: 74318540

Gene position: 2594194-2595057 (Clockwise)

Preceding gene: 74318530

Following gene: 74318541

Centisome position: 89.15

GC content: 70.14

Gene sequence:

>864_bases
ATGCTGTTGCTGAAGCTGATCGCCCGCGTGCCGCTGCCGCTGCTGCATAGCTTCGGCATTCTGTTCGGCTGGCTCGTCTA
TCTGGCGCCCGGGCGCCACGCGCAGCGCATGCGCGACAACCTGTCCGCCAGCGGGCTGTGTCGACCCGGTACGGAGTGCC
GCCGCCTGCTGCGGCAAACGATCGGCGAATCGGGCAAGGCCGTGGTCGAGTTGCTGCCGGTGTGGCTGCGTCCCCACGAG
GGGGTGCTCAGATTGGTGCGGGACACGCGCGACTGGGAACACATCGACGCCGCGCTCGCGGCCGGCCGTGGCGTGATCCT
GATCGCGCCGCACCTCGGCTGCTTCGAGATCATCAACCTCTATTACGCGGCACGTCATCCGTTCACCGCGATGTACAAGC
CGCCGCGCCAGCCAATGCTCGCCAGGCTCATGCTCATGGGCCGCCAGCGCGGCCAGGCGACGCTCGTGCCGACTGACCTT
TCCGGCGTGCGCGCGCTGCTCGCGGCACTCAAGCGCCACGAGGCGATCGGCATCCTGCCCGACCAGGTCGCGACCGGCGG
CGACGGGGTATGGGCGCCCTTCTTCGGCCGCCCGGCCTACACGCCGACACTCGTCGCCAGCCTGCAGCGCAAGACCGGCG
CGGCAGCGTTCTTCGTCGCGGCGGAGCGCCTGAGCTGGGGCCGCGGCTACCGCCTGCACGTGACCCCGGTCGGCGACACG
CTGCCCGATGACAAGACCGCAGCGGCCTTGCGGATCAACCAGGGCGTCGAAGCCTTCGTGCGGCGCTTTCCGGCGCAGTA
CATGTGGAGCTACAACCGCTACAAGCGCCCCGGCGGGGCCCCGCCTCCGGACGCAACGACGTGA

Upstream 100 bases:

>100_bases
GTGCTTCCTCCAGAGTCAATTCCCAGGACAGGACTTCGATCCACAACGGCGGCTTGCCCCCCTCGGGACGCAAGCCCGTG
TCGCGTCGCATCGCGGCGTG

Downstream 100 bases:

>100_bases
AGCAATCGCGCGCGCAGCTCCTTCATCCCTCGCTTTTCGGCGTCTGGCTCGGCGTCGGCCTGCTGTGGCTGCTGCACTGG
CTGCCTCTGCCGCTGCTGGC

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLLLKLIARVPLPLLHSFGILFGWLVYLAPGRHAQRMRDNLSASGLCRPGTECRRLLRQTIGESGKAVVELLPVWLRPHE
GVLRLVRDTRDWEHIDAALAAGRGVILIAPHLGCFEIINLYYAARHPFTAMYKPPRQPMLARLMLMGRQRGQATLVPTDL
SGVRALLAALKRHEAIGILPDQVATGGDGVWAPFFGRPAYTPTLVASLQRKTGAAAFFVAAERLSWGRGYRLHVTPVGDT
LPDDKTAAALRINQGVEAFVRRFPAQYMWSYNRYKRPGGAPPPDATT

Sequences:

>Translated_287_residues
MLLLKLIARVPLPLLHSFGILFGWLVYLAPGRHAQRMRDNLSASGLCRPGTECRRLLRQTIGESGKAVVELLPVWLRPHE
GVLRLVRDTRDWEHIDAALAAGRGVILIAPHLGCFEIINLYYAARHPFTAMYKPPRQPMLARLMLMGRQRGQATLVPTDL
SGVRALLAALKRHEAIGILPDQVATGGDGVWAPFFGRPAYTPTLVASLQRKTGAAAFFVAAERLSWGRGYRLHVTPVGDT
LPDDKTAAALRINQGVEAFVRRFPAQYMWSYNRYKRPGGAPPPDATT
>Mature_287_residues
MLLLKLIARVPLPLLHSFGILFGWLVYLAPGRHAQRMRDNLSASGLCRPGTECRRLLRQTIGESGKAVVELLPVWLRPHE
GVLRLVRDTRDWEHIDAALAAGRGVILIAPHLGCFEIINLYYAARHPFTAMYKPPRQPMLARLMLMGRQRGQATLVPTDL
SGVRALLAALKRHEAIGILPDQVATGGDGVWAPFFGRPAYTPTLVASLQRKTGAAAFFVAAERLSWGRGYRLHVTPVGDT
LPDDKTAAALRINQGVEAFVRRFPAQYMWSYNRYKRPGGAPPPDATT

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=282, Percent_Identity=28.0141843971631, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787292, Length=285, Percent_Identity=27.719298245614, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 31769; Mature: 31769

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLKLIARVPLPLLHSFGILFGWLVYLAPGRHAQRMRDNLSASGLCRPGTECRRLLRQT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IGESGKAVVELLPVWLRPHEGVLRLVRDTRDWEHIDAALAAGRGVILIAPHLGCFEIINL
HCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHH
YYAARHPFTAMYKPPRQPMLARLMLMGRQRGQATLVPTDLSGVRALLAALKRHEAIGILP
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
DQVATGGDGVWAPFFGRPAYTPTLVASLQRKTGAAAFFVAAERLSWGRGYRLHVTPVGDT
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCC
LPDDKTAAALRINQGVEAFVRRFPAQYMWSYNRYKRPGGAPPPDATT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLLLKLIARVPLPLLHSFGILFGWLVYLAPGRHAQRMRDNLSASGLCRPGTECRRLLRQT
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IGESGKAVVELLPVWLRPHEGVLRLVRDTRDWEHIDAALAAGRGVILIAPHLGCFEIINL
HCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHH
YYAARHPFTAMYKPPRQPMLARLMLMGRQRGQATLVPTDLSGVRALLAALKRHEAIGILP
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
DQVATGGDGVWAPFFGRPAYTPTLVASLQRKTGAAAFFVAAERLSWGRGYRLHVTPVGDT
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCC
LPDDKTAAALRINQGVEAFVRRFPAQYMWSYNRYKRPGGAPPPDATT
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]