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The map label for this gene is hmeB [H]

Identifier: 74318492

GI number: 74318492

Start: 2550123

End: 2551325

Strand: Reverse

Name: hmeB [H]

Synonym: Tbd_2474

Alternate gene names: 74318492

Gene position: 2551325-2550123 (Counterclockwise)

Preceding gene: 74318493

Following gene: 74318491

Centisome position: 87.68

GC content: 62.76

Gene sequence:

>1203_bases
ATGGCAAGCATTACCTTCCGCGAAGTCGAGGGCAGCAGCCTCAAGTACTGGCTGCTCCTGGGTGGCCTCGGCCTCTTCGT
CCTGTTCGGGGCGCTGTCCTGGAATTACATGCACCATCACGGGCATGTGGTCAGCGGCATGGACAACCAGATCGTATGGG
GCCTGCCGCATGTGTTCGCGGTTTTCCTGATCGTCGCCGCCTCTGGTGCGCTCAACGTCGCTTCGATCGCTTCGGTGTTC
AACAAGCCGCTCTACAAGCCGCTCGCCCCGCTGTCGGCGATTCTCGCGCTGGCGCTGATGCTCGGCGGCCTGCTGGTTCT
GGTGCTCGATCTCGGGCGTTCGGACCGTCTGATCGTCGCGATGACGAACTTCAACTTCAAGTCGATGTTCACCTGGAACG
TCTTCCTCTACTCGGGCTTCTTCGCCCTGGTCGGGGTGTACCTGTGGACGATGCTCGACCGCAATGTCAAGACCTATTCC
AAGACGGCGGGCACCGCGGCCTTCATCTGGCGGCTGCTGCTGACCACTGGTACGGGCTCGCTGTTCGGCTTTCTGGTCGC
GCGCGAACTCTACGGCAGCGCGATGCTGGCGCCGATGTTCATCATCATGTCCTTCGCCTACGGTCTCGCGATCTACCTGA
TGGTGCTGGTTGCTGCCTACGCCTGGAGCGGCCGCACCTTGGGTGATGCGGTCATGATGCGCCTGAAGAGCCTGCTCGCG
GTCTTCGTCGCCGCGGTGCTGTACTTCGTCGTTGTGCATCACCTGACCAACCTGTACTTCACCAAGTACCATGCAGTCGA
GGCGTTCATCCTGCGCGACGGTGGGATCTTCACGACACTGTTCTGGGTCGGCCAGATCGTGATCGGCGGCGTCGTTCCGC
TCGTGATCCTGCTGAGCGGCCTCGGCAGGCAGCGCGCATGGATACTCGTCGCCTGCGCGCTCGTGATCCTCGGTGGCGTC
GCGCAGATGTACGTCACCATCATCGGTGCCCAGGCGTATCCGCTCGACATGTTCCCGGGCCTCGACGAAACGAGCAGCTT
CTTCGACGGCGAGATCCACGCCTACGCGCCGAGCGTACCGGAGTTCTTCCTCGGACTCGGCGGCGTCGCGATCGCTCTGC
TGGTCACGACGTTCGCGGTCAAGGTGTTGCGCCTGCTGCCGGCCAGCCTCGACGACGCGACGGTCGCCAAGCTCGAACAT
TGA

Upstream 100 bases:

>100_bases
TAGCGAGATCTCGAAGCGTTTGCGCGAACTGCCCACCAAGCAGGTGCGTGCCGACCTCAAGCTCAATACCGGCGTTCGCT
ATCACGGAATCTAAAATAAT

Downstream 100 bases:

>100_bases
GCGCATGATCCTGCCGGGTCCAGTGGGGCCCGCAGGGGAAAGCCAGCCATGAGCCGGGCCGTCCTTTCTTCCACCGACAC
AAGCGCACGCGGGGTCCCCA

Product: molybdopterin oxidoreductase, membrane subunit

Products: NA

Alternate protein names: Hme subunit B [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MASITFREVEGSSLKYWLLLGGLGLFVLFGALSWNYMHHHGHVVSGMDNQIVWGLPHVFAVFLIVAASGALNVASIASVF
NKPLYKPLAPLSAILALALMLGGLLVLVLDLGRSDRLIVAMTNFNFKSMFTWNVFLYSGFFALVGVYLWTMLDRNVKTYS
KTAGTAAFIWRLLLTTGTGSLFGFLVARELYGSAMLAPMFIIMSFAYGLAIYLMVLVAAYAWSGRTLGDAVMMRLKSLLA
VFVAAVLYFVVVHHLTNLYFTKYHAVEAFILRDGGIFTTLFWVGQIVIGGVVPLVILLSGLGRQRAWILVACALVILGGV
AQMYVTIIGAQAYPLDMFPGLDETSSFFDGEIHAYAPSVPEFFLGLGGVAIALLVTTFAVKVLRLLPASLDDATVAKLEH

Sequences:

>Translated_400_residues
MASITFREVEGSSLKYWLLLGGLGLFVLFGALSWNYMHHHGHVVSGMDNQIVWGLPHVFAVFLIVAASGALNVASIASVF
NKPLYKPLAPLSAILALALMLGGLLVLVLDLGRSDRLIVAMTNFNFKSMFTWNVFLYSGFFALVGVYLWTMLDRNVKTYS
KTAGTAAFIWRLLLTTGTGSLFGFLVARELYGSAMLAPMFIIMSFAYGLAIYLMVLVAAYAWSGRTLGDAVMMRLKSLLA
VFVAAVLYFVVVHHLTNLYFTKYHAVEAFILRDGGIFTTLFWVGQIVIGGVVPLVILLSGLGRQRAWILVACALVILGGV
AQMYVTIIGAQAYPLDMFPGLDETSSFFDGEIHAYAPSVPEFFLGLGGVAIALLVTTFAVKVLRLLPASLDDATVAKLEH
>Mature_399_residues
ASITFREVEGSSLKYWLLLGGLGLFVLFGALSWNYMHHHGHVVSGMDNQIVWGLPHVFAVFLIVAASGALNVASIASVFN
KPLYKPLAPLSAILALALMLGGLLVLVLDLGRSDRLIVAMTNFNFKSMFTWNVFLYSGFFALVGVYLWTMLDRNVKTYSK
TAGTAAFIWRLLLTTGTGSLFGFLVARELYGSAMLAPMFIIMSFAYGLAIYLMVLVAAYAWSGRTLGDAVMMRLKSLLAV
FVAAVLYFVVVHHLTNLYFTKYHAVEAFILRDGGIFTTLFWVGQIVIGGVVPLVILLSGLGRQRAWILVACALVILGGVA
QMYVTIIGAQAYPLDMFPGLDETSSFFDGEIHAYAPSVPEFFLGLGGVAIALLVTTFAVKVLRLLPASLDDATVAKLEH

Specific function: Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, hmeB and hmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 43535; Mature: 43404

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASITFREVEGSSLKYWLLLGGLGLFVLFGALSWNYMHHHGHVVSGMDNQIVWGLPHVFA
CCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEECCHHHHH
VFLIVAASGALNVASIASVFNKPLYKPLAPLSAILALALMLGGLLVLVLDLGRSDRLIVA
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MTNFNFKSMFTWNVFLYSGFFALVGVYLWTMLDRNVKTYSKTAGTAAFIWRLLLTTGTGS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCHH
LFGFLVARELYGSAMLAPMFIIMSFAYGLAIYLMVLVAAYAWSGRTLGDAVMMRLKSLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VFVAAVLYFVVVHHLTNLYFTKYHAVEAFILRDGGIFTTLFWVGQIVIGGVVPLVILLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
LGRQRAWILVACALVILGGVAQMYVTIIGAQAYPLDMFPGLDETSSFFDGEIHAYAPSVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEECCCHH
EFFLGLGGVAIALLVTTFAVKVLRLLPASLDDATVAKLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
ASITFREVEGSSLKYWLLLGGLGLFVLFGALSWNYMHHHGHVVSGMDNQIVWGLPHVFA
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEECCHHHHH
VFLIVAASGALNVASIASVFNKPLYKPLAPLSAILALALMLGGLLVLVLDLGRSDRLIVA
HHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
MTNFNFKSMFTWNVFLYSGFFALVGVYLWTMLDRNVKTYSKTAGTAAFIWRLLLTTGTGS
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCHH
LFGFLVARELYGSAMLAPMFIIMSFAYGLAIYLMVLVAAYAWSGRTLGDAVMMRLKSLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VFVAAVLYFVVVHHLTNLYFTKYHAVEAFILRDGGIFTTLFWVGQIVIGGVVPLVILLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
LGRQRAWILVACALVILGGVAQMYVTIIGAQAYPLDMFPGLDETSSFFDGEIHAYAPSVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEECCCHH
EFFLGLGGVAIALLVTTFAVKVLRLLPASLDDATVAKLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]