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The map label for this gene is mdtA [H]

Identifier: 74318414

GI number: 74318414

Start: 2469164

End: 2470204

Strand: Direct

Name: mdtA [H]

Synonym: Tbd_2396

Alternate gene names: 74318414

Gene position: 2469164-2470204 (Clockwise)

Preceding gene: 74318413

Following gene: 74318415

Centisome position: 84.86

GC content: 69.64

Gene sequence:

>1041_bases
GTGCTGAGTCCCGTTCGTCTACTGGTCTGCGCCCTCCTGCTCTCGCCTTCCGCCTGGGGGGCACTACCGTTCGCGGTTGC
GCCGGTCAAATATCAGGTCGCGGACAGCGGCTACAGCACCGAAGCGAGCGTAGAAGCGGTCAAACAGTCGACGCTCGCCG
CGCAGGTTTCCGGCCGGGTTGCAGCGGTCAACTTCGACGCCGGCGATTACGTCAAGGCGGGCACGGTGCTCGTGCGGCTG
TCGGCGCAGGAGCTCTCGTCGGCCGTTGCCGGCAGCCAGGCACAGGTCGCGGAAGCCGCGGCGGCGCTCGCCAATGCACG
TGCCAATTACGAGCGCCAGCAGCAGCTGTTCCGCCAGCGATTCATCAGCCAGGCCGCGCTCGACCGCGCCACCGCCGAGT
TCCGCGCCGCCGAGGCAGCGGCGCGCGCAGCCCGCGCCGGGGCCGGCGAGTCTTCCGCGGTACGCGGCTACACCGTGATC
CGCGCGCCGTATTCGGGCGTCGTCGCGGCGCGCCACGTCGAGGTCGGTGAAACGGTGACACCCGGCAAGCCATTGATGAC
CGGCTTCGACCCCAAGGACATGCGGGTCGTCGCCAACATCCCGCAATACAAGCTTGCCACCGTGAAGGCCGCGCCGCGCG
TCGCGGTCGAAATCCCCTCGCTCAACAAGTGGATCGACGCCGTCGGCGTCACGGTCCTCCCCTCGGCCGACGCGGCGACG
CACACGGTCAAGGTGCGGCTCGACCTGCCGGCCGACGTCGACGGCGTCATCCCCGGCATGTTCGCGCGCGCGCACTTCTC
GACCGGAAGCGCGCGCAAGCTCGTGATCCCGCTCGCCGCGCTGGTGCGCCGGTCCGAGATCACGGCCGTCTACGTCGTCA
GCGGCGAGCGGGTGAGCCTGCGCCAGCTGCGCCTCGGGACGCCGAATGCGCGCGGCCAGGTCGAAGTGCTCGCGGGACTC
AATCCCGGCGACATCATCGCGCTCGAGCCGATCAAGGCCGGGATCTACGCCAAGAGCGCCGCCAACAAATCGGCCAAATA
A

Upstream 100 bases:

>100_bases
GCCCTACCGATTCCACGCATACCGCGGGCCTACGCAGCTTCGAGCCTTTGAATCTTCCGGAATCGACGGATACTTTAATG
AATTGCCTGGAGATTTGCCC

Downstream 100 bases:

>100_bases
GCGCAGACAGCCATGGGACTCTCCGGACGCGTCGCCCGCTTCTTCCTCACCTCGCAGCTGACGCCGCTCATCGCCCTGAT
GGCGGCCCTGCTCGGTCTCT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLSPVRLLVCALLLSPSAWGALPFAVAPVKYQVADSGYSTEASVEAVKQSTLAAQVSGRVAAVNFDAGDYVKAGTVLVRL
SAQELSSAVAGSQAQVAEAAAALANARANYERQQQLFRQRFISQAALDRATAEFRAAEAAARAARAGAGESSAVRGYTVI
RAPYSGVVAARHVEVGETVTPGKPLMTGFDPKDMRVVANIPQYKLATVKAAPRVAVEIPSLNKWIDAVGVTVLPSADAAT
HTVKVRLDLPADVDGVIPGMFARAHFSTGSARKLVIPLAALVRRSEITAVYVVSGERVSLRQLRLGTPNARGQVEVLAGL
NPGDIIALEPIKAGIYAKSAANKSAK

Sequences:

>Translated_346_residues
MLSPVRLLVCALLLSPSAWGALPFAVAPVKYQVADSGYSTEASVEAVKQSTLAAQVSGRVAAVNFDAGDYVKAGTVLVRL
SAQELSSAVAGSQAQVAEAAAALANARANYERQQQLFRQRFISQAALDRATAEFRAAEAAARAARAGAGESSAVRGYTVI
RAPYSGVVAARHVEVGETVTPGKPLMTGFDPKDMRVVANIPQYKLATVKAAPRVAVEIPSLNKWIDAVGVTVLPSADAAT
HTVKVRLDLPADVDGVIPGMFARAHFSTGSARKLVIPLAALVRRSEITAVYVVSGERVSLRQLRLGTPNARGQVEVLAGL
NPGDIIALEPIKAGIYAKSAANKSAK
>Mature_346_residues
MLSPVRLLVCALLLSPSAWGALPFAVAPVKYQVADSGYSTEASVEAVKQSTLAAQVSGRVAAVNFDAGDYVKAGTVLVRL
SAQELSSAVAGSQAQVAEAAAALANARANYERQQQLFRQRFISQAALDRATAEFRAAEAAARAARAGAGESSAVRGYTVI
RAPYSGVVAARHVEVGETVTPGKPLMTGFDPKDMRVVANIPQYKLATVKAAPRVAVEIPSLNKWIDAVGVTVLPSADAAT
HTVKVRLDLPADVDGVIPGMFARAHFSTGSARKLVIPLAALVRRSEITAVYVVSGERVSLRQLRLGTPNARGQVEVLAGL
NPGDIIALEPIKAGIYAKSAANKSAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=302, Percent_Identity=28.1456953642384, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081951, Length=188, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789929, Length=306, Percent_Identity=24.5098039215686, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788711, Length=211, Percent_Identity=27.0142180094787, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 36119; Mature: 36119

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPVRLLVCALLLSPSAWGALPFAVAPVKYQVADSGYSTEASVEAVKQSTLAAQVSGRV
CCCHHHHHHHHHHHCCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEE
AAVNFDAGDYVKAGTVLVRLSAQELSSAVAGSQAQVAEAAAALANARANYERQQQLFRQR
EEEEECCCCCEEECEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FISQAALDRATAEFRAAEAAARAARAGAGESSAVRGYTVIRAPYSGVVAARHVEVGETVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC
PGKPLMTGFDPKDMRVVANIPQYKLATVKAAPRVAVEIPSLNKWIDAVGVTVLPSADAAT
CCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEECCCHHHHHHHCCEEEECCCCCCE
HTVKVRLDLPADVDGVIPGMFARAHFSTGSARKLVIPLAALVRRSEITAVYVVSGERVSL
EEEEEEEECCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEE
RQLRLGTPNARGQVEVLAGLNPGDIIALEPIKAGIYAKSAANKSAK
EEEECCCCCCCCCEEEEECCCCCCEEEECCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MLSPVRLLVCALLLSPSAWGALPFAVAPVKYQVADSGYSTEASVEAVKQSTLAAQVSGRV
CCCHHHHHHHHHHHCCCCCCCCCEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEE
AAVNFDAGDYVKAGTVLVRLSAQELSSAVAGSQAQVAEAAAALANARANYERQQQLFRQR
EEEEECCCCCEEECEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FISQAALDRATAEFRAAEAAARAARAGAGESSAVRGYTVIRAPYSGVVAARHVEVGETVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCC
PGKPLMTGFDPKDMRVVANIPQYKLATVKAAPRVAVEIPSLNKWIDAVGVTVLPSADAAT
CCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEECCCHHHHHHHCCEEEECCCCCCE
HTVKVRLDLPADVDGVIPGMFARAHFSTGSARKLVIPLAALVRRSEITAVYVVSGERVSL
EEEEEEEECCCCCCCCCCCHHHHEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCEEE
RQLRLGTPNARGQVEVLAGLNPGDIIALEPIKAGIYAKSAANKSAK
EEEECCCCCCCCCEEEEECCCCCCEEEECCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA