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The map label for this gene is sodB [H]

Identifier: 74318274

GI number: 74318274

Start: 2330891

End: 2331595

Strand: Reverse

Name: sodB [H]

Synonym: Tbd_2256

Alternate gene names: 74318274

Gene position: 2331595-2330891 (Counterclockwise)

Preceding gene: 74318275

Following gene: 74318273

Centisome position: 80.13

GC content: 65.67

Gene sequence:

>705_bases
ATGAATGCATTAAAGATGGCATGGACCGCGCCGCCCACGCGACAGACCATGGAAACCGGGATGTCCGCAGGCGAATGCGG
CATCTGCACGTCCACGATCGAGGCGATGCGCTTCCCCTACGAGCTTCCGCCACTGCCGTACGGGCCGGACGCCCTGCGGC
CGCTGATTTCCGGGAACACGATCCGTTTCCACCATCGCGAGCATCACCAGCGTTACATCGACGGACTCAATCGCGGGATC
GACGACACCGAGTTCGGGGCGATGCCCTTGCGCGCGGTCATCCGCGCGACGGCCGGCAAACCGGAGACGGCCGTGATCTT
CAACAATGCCGCGCAGGCGTGGAACCACGCCTTCTACTGGGACAGCCTCACGCCGCAAGGCGGCGGCCTGCCACCGCCTG
CGCTGCGGAAAATGATCGACGCGTCGTTCGGCTCGGTCGACGCCTGCCTGCGCCAGCTCGCCCACGCGGCCATCGCGCAG
TTCGGCACGGGCTGGGTGTGGCTCGCGCGCGACGACAAGAAGATCCGGGTCGTGCGGACCTGTGGTGCCGACAACCCGCT
GACGCGGGAGCTGACCCCGCTGCTCGCGATCGACCTGTGGGAACACGCGTACTACCTCGATTACCAGAACCGGCTCGAAG
ATCACGTCAGCGGCGTGATCGGCCGCCTGGTCAACTGGGATTTCGCGGCGAAGAATCTTGTCTGA

Upstream 100 bases:

>100_bases
CAGTCTCGCGCGCCAGCCGGACGACAGCGTCGTGTTCCGCGCGGTACGGGGATGCGCCGCCGTCCCTGCGCGAGACAGGA
TCGAGGAGAACTCAGCAGTA

Downstream 100 bases:

>100_bases
CGAGCTTCGACGCCCCGCCCGAGGAAACCGTATGACTGACAGCACCCCGACGCCGGACCGCGAAACGCCGATCTACGACG
CGGTCCGCTACGTGACCCCC

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNALKMAWTAPPTRQTMETGMSAGECGICTSTIEAMRFPYELPPLPYGPDALRPLISGNTIRFHHREHHQRYIDGLNRGI
DDTEFGAMPLRAVIRATAGKPETAVIFNNAAQAWNHAFYWDSLTPQGGGLPPPALRKMIDASFGSVDACLRQLAHAAIAQ
FGTGWVWLARDDKKIRVVRTCGADNPLTRELTPLLAIDLWEHAYYLDYQNRLEDHVSGVIGRLVNWDFAAKNLV

Sequences:

>Translated_234_residues
MNALKMAWTAPPTRQTMETGMSAGECGICTSTIEAMRFPYELPPLPYGPDALRPLISGNTIRFHHREHHQRYIDGLNRGI
DDTEFGAMPLRAVIRATAGKPETAVIFNNAAQAWNHAFYWDSLTPQGGGLPPPALRKMIDASFGSVDACLRQLAHAAIAQ
FGTGWVWLARDDKKIRVVRTCGADNPLTRELTPLLAIDLWEHAYYLDYQNRLEDHVSGVIGRLVNWDFAAKNLV
>Mature_234_residues
MNALKMAWTAPPTRQTMETGMSAGECGICTSTIEAMRFPYELPPLPYGPDALRPLISGNTIRFHHREHHQRYIDGLNRGI
DDTEFGAMPLRAVIRATAGKPETAVIFNNAAQAWNHAFYWDSLTPQGGGLPPPALRKMIDASFGSVDACLRQLAHAAIAQ
FGTGWVWLARDDKKIRVVRTCGADNPLTRELTPLLAIDLWEHAYYLDYQNRLEDHVSGVIGRLVNWDFAAKNLV

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=194, Percent_Identity=35.5670103092784, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI67782305, Length=194, Percent_Identity=35.5670103092784, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI67782309, Length=194, Percent_Identity=29.3814432989691, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1787946, Length=195, Percent_Identity=47.1794871794872, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790342, Length=200, Percent_Identity=37, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17506561, Length=197, Percent_Identity=38.5786802030457, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17569479, Length=209, Percent_Identity=34.9282296650718, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6321796, Length=215, Percent_Identity=35.3488372093023, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136812, Length=197, Percent_Identity=33.502538071066, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 26083; Mature: 26083

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALKMAWTAPPTRQTMETGMSAGECGICTSTIEAMRFPYELPPLPYGPDALRPLISGNT
CCCCCCEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCE
IRFHHREHHQRYIDGLNRGIDDTEFGAMPLRAVIRATAGKPETAVIFNNAAQAWNHAFYW
EEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHCCEEEE
DSLTPQGGGLPPPALRKMIDASFGSVDACLRQLAHAAIAQFGTGWVWLARDDKKIRVVRT
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEE
CGADNPLTRELTPLLAIDLWEHAYYLDYQNRLEDHVSGVIGRLVNWDFAAKNLV
CCCCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MNALKMAWTAPPTRQTMETGMSAGECGICTSTIEAMRFPYELPPLPYGPDALRPLISGNT
CCCCCCEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCE
IRFHHREHHQRYIDGLNRGIDDTEFGAMPLRAVIRATAGKPETAVIFNNAAQAWNHAFYW
EEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHCCEEEE
DSLTPQGGGLPPPALRKMIDASFGSVDACLRQLAHAAIAQFGTGWVWLARDDKKIRVVRT
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEE
CGADNPLTRELTPLLAIDLWEHAYYLDYQNRLEDHVSGVIGRLVNWDFAAKNLV
CCCCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]