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The map label for this gene is ligD

Identifier: 74318265

GI number: 74318265

Start: 2321679

End: 2324219

Strand: Direct

Name: ligD

Synonym: Tbd_2247

Alternate gene names: NA

Gene position: 2321679-2324219 (Clockwise)

Preceding gene: 74318264

Following gene: 74318266

Centisome position: 79.79

GC content: 69.3

Gene sequence:

>2541_bases
ATGGCCAAGCGCGACCCGCTTTCCACCTACACCGAGAAACGCGATTTTTCGATCAGCCCGGAGCCAGTGTCGGGCGGCCA
GGCCAATGAGGCGGCGCGCTCGTTCGTCGTGCAGAAACACTGGGCGACGCGACTGCATTACGACTTCCGGCTCGAACTCG
ACGGCAGCATGAAAAGCTGGGCCGTACCGAAGGGGCCGAGCCTCGACCCCGCGGACAAGCGCATGGCCGTGCACGTCGAG
GACCACCCGATCGCCTACAACGCGTTCGAGGGGACGATCCCGCCCAGGCAATACGGCGCCGGCAAGGTCATCATCTGGGA
CAAAGGCACCTGGGTTCCGCTCGTCGATCCGCGCCGCGGCTACGAGGAAGGCCATCTCAAATTCGAACTCCACGGTCACA
AGCTGCAGGGGCGGTGGGCGCTCGTGCGCATGAAGGGTAAAGGCGAAGCCAAGGAGCCCTGGCTCCTGATCAAGGAAAAG
GACGAACATGCGCGCCCCGCCGCCGACTACAGCGTCGTCGACGCCCTGCCCGACAGCGTCGCGGACAAGGACGACGCCGC
GGCCGTGACGAAGGCCGCGGCGCCGCGGCGGCGTGCAGGCGAAACGCCGCGCCCGCGCAAGGCGCGCGCGGCGAAGGCCA
CGGAAAAAGCGGGCGCGGCGGCCGTCGAGGGCGCGGTGAAAAGCGCGCTGCCGGCGACGCTGGCCCCCCAGCTCGCGACG
CTCGCCGACAAGCCGCCGGACGACGGCGACGGCTGGGTCTACGAGGTAAAGTTCGACGGCTATCGCATGCTCGCGCGCAT
CGACAAGACGGTCCGCCTGTTCACGCGCAACGGCAACGACTGGAGCCACAGGCTCGCGCCGCTGGTCAAGGCGATCGAAG
CGGCCGGGCTGCGGCCCGGCTGGCTCGACGGCGAGGTCGTCGTACCGAACGCGGCCGGCGTGCCGGACTTCCAGGCGCTG
CAGAACGCCTTCGACCAGGCGCGCGCGGACGCCATCGTCTACTACGTCTTCGACCTGCCGTTCTACGACGGTTACGACCT
GCGCGCGGCGCCGCTCGTCGCGCGCAAGGCGCTGCTCGCGGGCTTGCTCGACACGCCGCACAGCGACGCGCTGCGCTTGA
GTGAAAGCTTCGACGCAGCGCCGCGCGACATCCTCGCATCAGCCTGCAAGATGGGGCTCGAGGGCGTGATCGCGAAGCGC
CGCGACGCGCCCTACGTCTCGCGCCGCTCGACCGACTGGCTCAAGCTCAAGTGCACGCGGCGCCAGGAATTCGTGATCGG
CGGCTACACCGATCCGCGCGGCTCCCGGCCCGGGCTCGGCTCGCTGCTGCTCGGCGTGCACGACGCGCGCGGCGAACTCG
TCTACGCCGGCAACGTCGGCACCGGCTTCGACCACGGCACGCTCGGCGATCTCAGGAAAAAACTCGCGGCGCACGCGCGC
GACACGAGCCCGTTCGTCGACGCGACGGGCATCGCGGGCAAGCCGCACTGGGTCGACCCCAAACTTGTCGCCGAGGTGTC
GTTCGGCGAATGGACCAAGAGCGGCCGGATCCGCCACGCGGTGTTCGAGGGGCTGCGGCTCGACAAGCGCGCGGCCAGCG
TCGTCCGCGAGGAACCCGTTGCCGCGGCGGCCGCCGCCCCGCGCCTGCCGGCCGATCTGAAGGTCTCGCACCCGGAGCGC
GTGGTCGACAAGGCGAGCGGCACCACCAAGCTCGCGCTCATCGCCTACTACGCGCGGGTCGCCCCGCTGATGATGCCGCA
CCTGAAGGCGCGGCCGGTGTCGCTGGTGCGCGCGCCCGACGGCGTGGGCGGATCGCTCTTTTTCCAGAAGCACGTCGAGG
CGTCGCAGATGCGCGGCGTCAAGACGCTGCCGCGCACGCTCGACCCGGGTCACGCGCCGCTCATCGAGGTCGCCGCGGCC
GAGGGCCTGCTGACCGCAGCGCAGATGAACGTGATCGAATTCCATACCTGGAACGCGCGCAAGACCCGGATCGACAAGCC
GGACCGCATGACCTTCGACCTCGATCCCGGCGAGGGCGTCGGCTGGACCACGGTGCAGGAATCCGCCCACCTCGTGCGCG
AATTTCTCTCCCAGCTCGGGCTGGCGTCGTTTCTCAAGACCAGCGGCGGCAAGGGCCTGCACATCGTCGTGCCGCTCAAG
CGCCTGCACGACTGGGATACGGTCAAGGATTTTTCGCACGCGATCGTGCGCCATCTCGCGAGGACGCTGCCGCAACGCTT
TGCCGCCAAGAGCGGGCCGAAAAACCGGGTCGGCAAGATCTTCATCGATTACCTGCGCAACGGCTTCGGCGCGACCACGG
TCGCCGCCTGGTCGGTGCGCGCACGCCCAGGGCTCGGCGTCTCGGTGCCACTCGAATGGCGCGAACTCGACGCGCTCACG
AGCGCTGCGCAGTGGACGGTCCCGAACATCGACTCGCGCCTCGAAATCGGCAACGCGCCGTGGGAGGCCTACGACGCCTC
GAGCCACAGCCTGACCCGGGCGATGAAGACGCTGGGCCACGTTCCGAAAACGCCGGCATAG

Upstream 100 bases:

>100_bases
GAAGCAGGACAAACAGCCTTCGGCGCGCGCCACGCCCAAGGCCCGCGCGGGTGCGAAGACGCCGACCAAGTCGGGCGGCA
AGCGCAAGGCCGCGTAACCA

Downstream 100 bases:

>100_bases
GCCGCGTCCGACAACACGTCGCGCCGATCGCCCTTGAAGCACCGCGCGCCGCGCCGTGAAATAGAGGGGAGCGACCCTCG
GCCCGCCCGATGTGGTCGCC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 845

Protein sequence:

>846_residues
MAKRDPLSTYTEKRDFSISPEPVSGGQANEAARSFVVQKHWATRLHYDFRLELDGSMKSWAVPKGPSLDPADKRMAVHVE
DHPIAYNAFEGTIPPRQYGAGKVIIWDKGTWVPLVDPRRGYEEGHLKFELHGHKLQGRWALVRMKGKGEAKEPWLLIKEK
DEHARPAADYSVVDALPDSVADKDDAAAVTKAAAPRRRAGETPRPRKARAAKATEKAGAAAVEGAVKSALPATLAPQLAT
LADKPPDDGDGWVYEVKFDGYRMLARIDKTVRLFTRNGNDWSHRLAPLVKAIEAAGLRPGWLDGEVVVPNAAGVPDFQAL
QNAFDQARADAIVYYVFDLPFYDGYDLRAAPLVARKALLAGLLDTPHSDALRLSESFDAAPRDILASACKMGLEGVIAKR
RDAPYVSRRSTDWLKLKCTRRQEFVIGGYTDPRGSRPGLGSLLLGVHDARGELVYAGNVGTGFDHGTLGDLRKKLAAHAR
DTSPFVDATGIAGKPHWVDPKLVAEVSFGEWTKSGRIRHAVFEGLRLDKRAASVVREEPVAAAAAAPRLPADLKVSHPER
VVDKASGTTKLALIAYYARVAPLMMPHLKARPVSLVRAPDGVGGSLFFQKHVEASQMRGVKTLPRTLDPGHAPLIEVAAA
EGLLTAAQMNVIEFHTWNARKTRIDKPDRMTFDLDPGEGVGWTTVQESAHLVREFLSQLGLASFLKTSGGKGLHIVVPLK
RLHDWDTVKDFSHAIVRHLARTLPQRFAAKSGPKNRVGKIFIDYLRNGFGATTVAAWSVRARPGLGVSVPLEWRELDALT
SAAQWTVPNIDSRLEIGNAPWEAYDASSHSLTRAMKTLGHVPKTPA

Sequences:

>Translated_846_residues
MAKRDPLSTYTEKRDFSISPEPVSGGQANEAARSFVVQKHWATRLHYDFRLELDGSMKSWAVPKGPSLDPADKRMAVHVE
DHPIAYNAFEGTIPPRQYGAGKVIIWDKGTWVPLVDPRRGYEEGHLKFELHGHKLQGRWALVRMKGKGEAKEPWLLIKEK
DEHARPAADYSVVDALPDSVADKDDAAAVTKAAAPRRRAGETPRPRKARAAKATEKAGAAAVEGAVKSALPATLAPQLAT
LADKPPDDGDGWVYEVKFDGYRMLARIDKTVRLFTRNGNDWSHRLAPLVKAIEAAGLRPGWLDGEVVVPNAAGVPDFQAL
QNAFDQARADAIVYYVFDLPFYDGYDLRAAPLVARKALLAGLLDTPHSDALRLSESFDAAPRDILASACKMGLEGVIAKR
RDAPYVSRRSTDWLKLKCTRRQEFVIGGYTDPRGSRPGLGSLLLGVHDARGELVYAGNVGTGFDHGTLGDLRKKLAAHAR
DTSPFVDATGIAGKPHWVDPKLVAEVSFGEWTKSGRIRHAVFEGLRLDKRAASVVREEPVAAAAAAPRLPADLKVSHPER
VVDKASGTTKLALIAYYARVAPLMMPHLKARPVSLVRAPDGVGGSLFFQKHVEASQMRGVKTLPRTLDPGHAPLIEVAAA
EGLLTAAQMNVIEFHTWNARKTRIDKPDRMTFDLDPGEGVGWTTVQESAHLVREFLSQLGLASFLKTSGGKGLHIVVPLK
RLHDWDTVKDFSHAIVRHLARTLPQRFAAKSGPKNRVGKIFIDYLRNGFGATTVAAWSVRARPGLGVSVPLEWRELDALT
SAAQWTVPNIDSRLEIGNAPWEAYDASSHSLTRAMKTLGHVPKTPA
>Mature_845_residues
AKRDPLSTYTEKRDFSISPEPVSGGQANEAARSFVVQKHWATRLHYDFRLELDGSMKSWAVPKGPSLDPADKRMAVHVED
HPIAYNAFEGTIPPRQYGAGKVIIWDKGTWVPLVDPRRGYEEGHLKFELHGHKLQGRWALVRMKGKGEAKEPWLLIKEKD
EHARPAADYSVVDALPDSVADKDDAAAVTKAAAPRRRAGETPRPRKARAAKATEKAGAAAVEGAVKSALPATLAPQLATL
ADKPPDDGDGWVYEVKFDGYRMLARIDKTVRLFTRNGNDWSHRLAPLVKAIEAAGLRPGWLDGEVVVPNAAGVPDFQALQ
NAFDQARADAIVYYVFDLPFYDGYDLRAAPLVARKALLAGLLDTPHSDALRLSESFDAAPRDILASACKMGLEGVIAKRR
DAPYVSRRSTDWLKLKCTRRQEFVIGGYTDPRGSRPGLGSLLLGVHDARGELVYAGNVGTGFDHGTLGDLRKKLAAHARD
TSPFVDATGIAGKPHWVDPKLVAEVSFGEWTKSGRIRHAVFEGLRLDKRAASVVREEPVAAAAAAPRLPADLKVSHPERV
VDKASGTTKLALIAYYARVAPLMMPHLKARPVSLVRAPDGVGGSLFFQKHVEASQMRGVKTLPRTLDPGHAPLIEVAAAE
GLLTAAQMNVIEFHTWNARKTRIDKPDRMTFDLDPGEGVGWTTVQESAHLVREFLSQLGLASFLKTSGGKGLHIVVPLKR
LHDWDTVKDFSHAIVRHLARTLPQRFAAKSGPKNRVGKIFIDYLRNGFGATTVAAWSVRARPGLGVSVPLEWRELDALTS
AAQWTVPNIDSRLEIGNAPWEAYDASSHSLTRAMKTLGHVPKTPA

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 92492; Mature: 92361

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRDPLSTYTEKRDFSISPEPVSGGQANEAARSFVVQKHWATRLHYDFRLELDGSMKSW
CCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHC
AVPKGPSLDPADKRMAVHVEDHPIAYNAFEGTIPPRQYGAGKVIIWDKGTWVPLVDPRRG
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCHHCCCCEEEEECCCCEEECCCCCCC
YEEGHLKFELHGHKLQGRWALVRMKGKGEAKEPWLLIKEKDEHARPAADYSVVDALPDSV
CCCCCEEEEEECCEECCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCHHH
ADKDDAAAVTKAAAPRRRAGETPRPRKARAAKATEKAGAAAVEGAVKSALPATLAPQLAT
CCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
LADKPPDDGDGWVYEVKFDGYRMLARIDKTVRLFTRNGNDWSHRLAPLVKAIEAAGLRPG
HCCCCCCCCCCEEEEEEECCCHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
WLDGEVVVPNAAGVPDFQALQNAFDQARADAIVYYVFDLPFYDGYDLRAAPLVARKALLA
CCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
GLLDTPHSDALRLSESFDAAPRDILASACKMGLEGVIAKRRDAPYVSRRSTDWLKLKCTR
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEECC
RQEFVIGGYTDPRGSRPGLGSLLLGVHDARGELVYAGNVGTGFDHGTLGDLRKKLAAHAR
CCEEEEECCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
DTSPFVDATGIAGKPHWVDPKLVAEVSFGEWTKSGRIRHAVFEGLRLDKRAASVVREEPV
CCCCCCCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AAAAAAPRLPADLKVSHPERVVDKASGTTKLALIAYYARVAPLMMPHLKARPVSLVRAPD
HHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GVGGSLFFQKHVEASQMRGVKTLPRTLDPGHAPLIEVAAAEGLLTAAQMNVIEFHTWNAR
CCCCCHHHHHHCCHHHHCCCHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCEEEEEECCCC
KTRIDKPDRMTFDLDPGEGVGWTTVQESAHLVREFLSQLGLASFLKTSGGKGLHIVVPLK
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHH
RLHDWDTVKDFSHAIVRHLARTLPQRFAAKSGPKNRVGKIFIDYLRNGFGATTVAAWSVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEE
ARPGLGVSVPLEWRELDALTSAAQWTVPNIDSRLEIGNAPWEAYDASSHSLTRAMKTLGH
CCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCC
VPKTPA
CCCCCC
>Mature Secondary Structure 
AKRDPLSTYTEKRDFSISPEPVSGGQANEAARSFVVQKHWATRLHYDFRLELDGSMKSW
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCHHC
AVPKGPSLDPADKRMAVHVEDHPIAYNAFEGTIPPRQYGAGKVIIWDKGTWVPLVDPRRG
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCHHCCCCEEEEECCCCEEECCCCCCC
YEEGHLKFELHGHKLQGRWALVRMKGKGEAKEPWLLIKEKDEHARPAADYSVVDALPDSV
CCCCCEEEEEECCEECCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCHHH
ADKDDAAAVTKAAAPRRRAGETPRPRKARAAKATEKAGAAAVEGAVKSALPATLAPQLAT
CCCCHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
LADKPPDDGDGWVYEVKFDGYRMLARIDKTVRLFTRNGNDWSHRLAPLVKAIEAAGLRPG
HCCCCCCCCCCEEEEEEECCCHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
WLDGEVVVPNAAGVPDFQALQNAFDQARADAIVYYVFDLPFYDGYDLRAAPLVARKALLA
CCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
GLLDTPHSDALRLSESFDAAPRDILASACKMGLEGVIAKRRDAPYVSRRSTDWLKLKCTR
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCEEEEEECC
RQEFVIGGYTDPRGSRPGLGSLLLGVHDARGELVYAGNVGTGFDHGTLGDLRKKLAAHAR
CCEEEEECCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
DTSPFVDATGIAGKPHWVDPKLVAEVSFGEWTKSGRIRHAVFEGLRLDKRAASVVREEPV
CCCCCCCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AAAAAAPRLPADLKVSHPERVVDKASGTTKLALIAYYARVAPLMMPHLKARPVSLVRAPD
HHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
GVGGSLFFQKHVEASQMRGVKTLPRTLDPGHAPLIEVAAAEGLLTAAQMNVIEFHTWNAR
CCCCCHHHHHHCCHHHHCCCHHCCCCCCCCCCCHHHHHHHCCHHHHHHCCEEEEEECCCC
KTRIDKPDRMTFDLDPGEGVGWTTVQESAHLVREFLSQLGLASFLKTSGGKGLHIVVPLK
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHH
RLHDWDTVKDFSHAIVRHLARTLPQRFAAKSGPKNRVGKIFIDYLRNGFGATTVAAWSVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEE
ARPGLGVSVPLEWRELDALTSAAQWTVPNIDSRLEIGNAPWEAYDASSHSLTRAMKTLGH
CCCCCCEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCC
VPKTPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]