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The map label for this gene is tolQ [H]

Identifier: 74318227

GI number: 74318227

Start: 2288565

End: 2289260

Strand: Reverse

Name: tolQ [H]

Synonym: Tbd_2209

Alternate gene names: 74318227

Gene position: 2289260-2288565 (Counterclockwise)

Preceding gene: 74318228

Following gene: 74318226

Centisome position: 78.67

GC content: 65.37

Gene sequence:

>696_bases
GTGAACCCCGATATCAGTCAGGACCTGTCGCTGCTCCATCTCATCCTCAACGCCTCGCTGCCCGTGCAGATCGTGATGCT
GCTTCTGCTTGGCGCATCGCTGATGTCGTGGTGGTACATCTTCATCAAGATGTTCGCGCTCAAGCGCGCGCTGCGCGTCA
CCGATCGCTTCGAGCACGAGTTCTGGGGCGGCGGCGACATTCATGCGATGTACGAAAGGGTCGCCGCCGGCCGTGAGGAA
GCGAGCGAGATGGAGCGCATCTTCGAAGCCGGCTTTCGCGAGTTCATGAAGCTGCGCCAGCAGGCCGGGCTCTCGCTCAA
CGTCATCATCGACGGCACGCGACGGGCGATGCGCGCGAGCTATCAGCGCGAGCTCGACGCGCTCGAGTCGCATCTCGCGT
TTCTCGCCACGGTCGGCTCGGTGTCGCCCTACGTGGGCCTGTTCGGCACGGTGTGGGGCATCATGCTGGCCTTCCAGGGC
CTCGCGACCGTGGCGCAGGCGACGCTCGCCCAGGTCGCGCCGGGCATCGCCGAGGCGCTGATCGCGACCGCGATGGGGCT
CTTTGCGGCGATCCCCGCGGTCGTCGGCTACAACCGCTACACCCACGACGTCGACCGTCTCGCCAACCGGATGGAGAGCT
TCATGGAGGAGTTTTCCAACATCCTGCAGCGACAGGTCACGCAACGGCCCGCCTGA

Upstream 100 bases:

>100_bases
GTCTAGCTGAGGCCGTGGTGACGCTGGCCTGCGTCGACGTCGCGAATTTCAAACCCGTTAAAATGCCCGCAACGATACTT
CAAGCCCTGAGCCCCACGCC

Downstream 100 bases:

>100_bases
ACGCGATGGCACGCTCGCGCAAACAGGTCGCCCAGATCAACGTCGTGCCGATGATCGACGTGATGTTGGTGCTGCTGGTG
ATCTTCATGGTCACCGCACC

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNPDISQDLSLLHLILNASLPVQIVMLLLLGASLMSWWYIFIKMFALKRALRVTDRFEHEFWGGGDIHAMYERVAAGREE
ASEMERIFEAGFREFMKLRQQAGLSLNVIIDGTRRAMRASYQRELDALESHLAFLATVGSVSPYVGLFGTVWGIMLAFQG
LATVAQATLAQVAPGIAEALIATAMGLFAAIPAVVGYNRYTHDVDRLANRMESFMEEFSNILQRQVTQRPA

Sequences:

>Translated_231_residues
MNPDISQDLSLLHLILNASLPVQIVMLLLLGASLMSWWYIFIKMFALKRALRVTDRFEHEFWGGGDIHAMYERVAAGREE
ASEMERIFEAGFREFMKLRQQAGLSLNVIIDGTRRAMRASYQRELDALESHLAFLATVGSVSPYVGLFGTVWGIMLAFQG
LATVAQATLAQVAPGIAEALIATAMGLFAAIPAVVGYNRYTHDVDRLANRMESFMEEFSNILQRQVTQRPA
>Mature_231_residues
MNPDISQDLSLLHLILNASLPVQIVMLLLLGASLMSWWYIFIKMFALKRALRVTDRFEHEFWGGGDIHAMYERVAAGREE
ASEMERIFEAGFREFMKLRQQAGLSLNVIIDGTRRAMRASYQRELDALESHLAFLATVGSVSPYVGLFGTVWGIMLAFQG
LATVAQATLAQVAPGIAEALIATAMGLFAAIPAVVGYNRYTHDVDRLANRMESFMEEFSNILQRQVTQRPA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=50, Blast_Score=208, Evalue=2e-55,
Organism=Escherichia coli, GI1789381, Length=213, Percent_Identity=36.150234741784, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25816; Mature: 25816

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPDISQDLSLLHLILNASLPVQIVMLLLLGASLMSWWYIFIKMFALKRALRVTDRFEHE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWGGGDIHAMYERVAAGREEASEMERIFEAGFREFMKLRQQAGLSLNVIIDGTRRAMRAS
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
YQRELDALESHLAFLATVGSVSPYVGLFGTVWGIMLAFQGLATVAQATLAQVAPGIAEAL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IATAMGLFAAIPAVVGYNRYTHDVDRLANRMESFMEEFSNILQRQVTQRPA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPDISQDLSLLHLILNASLPVQIVMLLLLGASLMSWWYIFIKMFALKRALRVTDRFEHE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWGGGDIHAMYERVAAGREEASEMERIFEAGFREFMKLRQQAGLSLNVIIDGTRRAMRAS
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
YQRELDALESHLAFLATVGSVSPYVGLFGTVWGIMLAFQGLATVAQATLAQVAPGIAEAL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IATAMGLFAAIPAVVGYNRYTHDVDRLANRMESFMEEFSNILQRQVTQRPA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]