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The map label for this gene is ydcR [H]

Identifier: 74317990

GI number: 74317990

Start: 2062238

End: 2063650

Strand: Reverse

Name: ydcR [H]

Synonym: Tbd_1972

Alternate gene names: 74317990

Gene position: 2063650-2062238 (Counterclockwise)

Preceding gene: 74317991

Following gene: 74317987

Centisome position: 70.92

GC content: 64.76

Gene sequence:

>1413_bases
ATGAGCCGCTATCACGACATTGCCGAGCACACAGAGAAACTGATCGTCGACGGCGTGCTGCGCGCGGGCGACCGCCTGCC
TTCGGTGCGCCAGGCCTGCCGCATCCATGATGTGAGTCCCGTTACCGTCACGCAGGCTTACTACCTGCTGGAGAGCCGCG
GCCTGATCGAGGCGCGGCCGAAGTCGGGCTATTTCGTGCGCGCGCGGCTCCGGCAGAACCTGCGCGAGCCGGACATGACG
CGCCCGGTCGCCAGCTCGACACAGTTGCAGGTCAGCGATTTCATTTTCCAGATTCTCGAAAGCGTCCGCGATCCGTCGGT
CGTGCCGCTGGGTTCGAGCTTCCCGAGCCCGTTTCTGTTTCCGCTCGACAAGCTCGGGCGTTTTCTGGCGAGCGCCGCAC
GCAAGCTCGACCCGCTCGCCACGGTCATCGACCTGCCGCCCGGAAACGAGGAGTTGCGGCGGCAACTGGCCTTGCGCTAC
CTCGCGTCCGGCGCGTCCGTTTCGCCCGACGAAATCGTCATCACGTGCGGCGCGATGGAGGCGCTCAACCTCTGTCTGCA
GGCGGTCGCCCGGCCCGGCGACCTGATCGCCATCGAATCGCCGGCCTTTTACGCCGGGCTGCAGGCGAGCGAGCGGCTCG
GGTTGAAGGTGATCGAAATCCCGACCCACCCGCGCGAGGGCATCAGCATGGCCGCCCTGGCGGAGACGCTGCAGCGCCAT
CCGGTCAAAGCCTGCCTGTTCATGCTCAATTTCTCGAATCCGACAGGCAGCCTCGTTCCGGACGAGCGGAGAAAGGAACT
CGTCGAATTGCTGCATCGTCACGACGTGCCGCTCATCGAAGACGACGTCTACGCGGAGCTTTATTTCGGCCGCCAGGCGC
CCTTGTGCACCAAAGCCGTGGATCCGCACGGGATGGTGATGCACGTTTCGTCGTTCTCGAAAAATCTCGCGCCCGGATAC
CGCGTAGGCTGGGTCGCGGCCGGGCGCTTCGCCGAGCGCGTCCAGCGGCAAAAATTCTCGACGACGCTGGCGACGACGAT
TCCCGTGCAAATCGCGCTCGCGGAATATCTGAAACACGGCGGCTACGAGAACCACCTGCGGCACTTGCGGCGCAAGCTCG
CCGAACAGGAAGCCGCACTGGCCGCGGCGATCGAGCCGAATTTTCCGGAAGGCACGCGCCTGGCGCGGCCCGACGGCGGC
TATTTCCTGTGGCTGGAACTACCGCCGCAGATCGACACGCTGGTCTTGCATCAACGCACGCTGGCGCGAGGCATCAGCAC
CGCGCCCGGCCCCATTTTTTCGGCGAAGCGGGAATTCACCCACCATCTGCGGCTGAATTTCGGCCATTCGGACTCGCAGC
GCCAGCAGGATGCGATGGTGACGCTGGGGCAATTGATCGCCGAACAGTTATAG

Upstream 100 bases:

>100_bases
ACCGGCTCGCGGCGGTGCGGCGGCTGAAGATTTCGAAGACAACGGATCAGGCGAAGCCACCGGGTGAAAGCGCCGCCGCC
AACGCTGATAGCATCTGCGT

Downstream 100 bases:

>100_bases
CGTCGCCCAACGGGCGAACTGGTCGCCGAAAAAGGCGATGCCGATCAGCGCAAGCGGCGCGAAGGCGACGAACGCCAGCA
CCACCCGGCGGATGAATGGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSRYHDIAEHTEKLIVDGVLRAGDRLPSVRQACRIHDVSPVTVTQAYYLLESRGLIEARPKSGYFVRARLRQNLREPDMT
RPVASSTQLQVSDFIFQILESVRDPSVVPLGSSFPSPFLFPLDKLGRFLASAARKLDPLATVIDLPPGNEELRRQLALRY
LASGASVSPDEIVITCGAMEALNLCLQAVARPGDLIAIESPAFYAGLQASERLGLKVIEIPTHPREGISMAALAETLQRH
PVKACLFMLNFSNPTGSLVPDERRKELVELLHRHDVPLIEDDVYAELYFGRQAPLCTKAVDPHGMVMHVSSFSKNLAPGY
RVGWVAAGRFAERVQRQKFSTTLATTIPVQIALAEYLKHGGYENHLRHLRRKLAEQEAALAAAIEPNFPEGTRLARPDGG
YFLWLELPPQIDTLVLHQRTLARGISTAPGPIFSAKREFTHHLRLNFGHSDSQRQQDAMVTLGQLIAEQL

Sequences:

>Translated_470_residues
MSRYHDIAEHTEKLIVDGVLRAGDRLPSVRQACRIHDVSPVTVTQAYYLLESRGLIEARPKSGYFVRARLRQNLREPDMT
RPVASSTQLQVSDFIFQILESVRDPSVVPLGSSFPSPFLFPLDKLGRFLASAARKLDPLATVIDLPPGNEELRRQLALRY
LASGASVSPDEIVITCGAMEALNLCLQAVARPGDLIAIESPAFYAGLQASERLGLKVIEIPTHPREGISMAALAETLQRH
PVKACLFMLNFSNPTGSLVPDERRKELVELLHRHDVPLIEDDVYAELYFGRQAPLCTKAVDPHGMVMHVSSFSKNLAPGY
RVGWVAAGRFAERVQRQKFSTTLATTIPVQIALAEYLKHGGYENHLRHLRRKLAEQEAALAAAIEPNFPEGTRLARPDGG
YFLWLELPPQIDTLVLHQRTLARGISTAPGPIFSAKREFTHHLRLNFGHSDSQRQQDAMVTLGQLIAEQL
>Mature_469_residues
SRYHDIAEHTEKLIVDGVLRAGDRLPSVRQACRIHDVSPVTVTQAYYLLESRGLIEARPKSGYFVRARLRQNLREPDMTR
PVASSTQLQVSDFIFQILESVRDPSVVPLGSSFPSPFLFPLDKLGRFLASAARKLDPLATVIDLPPGNEELRRQLALRYL
ASGASVSPDEIVITCGAMEALNLCLQAVARPGDLIAIESPAFYAGLQASERLGLKVIEIPTHPREGISMAALAETLQRHP
VKACLFMLNFSNPTGSLVPDERRKELVELLHRHDVPLIEDDVYAELYFGRQAPLCTKAVDPHGMVMHVSSFSKNLAPGYR
VGWVAAGRFAERVQRQKFSTTLATTIPVQIALAEYLKHGGYENHLRHLRRKLAEQEAALAAAIEPNFPEGTRLARPDGGY
FLWLELPPQIDTLVLHQRTLARGISTAPGPIFSAKREFTHHLRLNFGHSDSQRQQDAMVTLGQLIAEQL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=398, Percent_Identity=25.1256281407035, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI33469970, Length=398, Percent_Identity=25.1256281407035, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4507369, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787710, Length=470, Percent_Identity=45.7446808510638, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1790797, Length=468, Percent_Identity=37.8205128205128, Blast_Score=313, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17567663, Length=348, Percent_Identity=21.8390804597701, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321000, Length=182, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356535, Length=293, Percent_Identity=22.1843003412969, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859735, Length=181, Percent_Identity=24.8618784530387, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52257; Mature: 52126

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYHDIAEHTEKLIVDGVLRAGDRLPSVRQACRIHDVSPVTVTQAYYLLESRGLIEARP
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECC
KSGYFVRARLRQNLREPDMTRPVASSTQLQVSDFIFQILESVRDPSVVPLGSSFPSPFLF
CCCCEEEHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
PLDKLGRFLASAARKLDPLATVIDLPPGNEELRRQLALRYLASGASVSPDEIVITCGAME
CHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHH
ALNLCLQAVARPGDLIAIESPAFYAGLQASERLGLKVIEIPTHPREGISMAALAETLQRH
HHHHHHHHHCCCCCEEEECCCCHHHCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHC
PVKACLFMLNFSNPTGSLVPDERRKELVELLHRHDVPLIEDDVYAELYFGRQAPLCTKAV
CHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHCCC
DPHGMVMHVSSFSKNLAPGYRVGWVAAGRFAERVQRQKFSTTLATTIPVQIALAEYLKHG
CCCCEEEEECHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYENHLRHLRRKLAEQEAALAAAIEPNFPEGTRLARPDGGYFLWLELPPQIDTLVLHQRT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
LARGISTAPGPIFSAKREFTHHLRLNFGHSDSQRQQDAMVTLGQLIAEQL
HHHCCCCCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRYHDIAEHTEKLIVDGVLRAGDRLPSVRQACRIHDVSPVTVTQAYYLLESRGLIEARP
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECC
KSGYFVRARLRQNLREPDMTRPVASSTQLQVSDFIFQILESVRDPSVVPLGSSFPSPFLF
CCCCEEEHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
PLDKLGRFLASAARKLDPLATVIDLPPGNEELRRQLALRYLASGASVSPDEIVITCGAME
CHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHH
ALNLCLQAVARPGDLIAIESPAFYAGLQASERLGLKVIEIPTHPREGISMAALAETLQRH
HHHHHHHHHCCCCCEEEECCCCHHHCCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHC
PVKACLFMLNFSNPTGSLVPDERRKELVELLHRHDVPLIEDDVYAELYFGRQAPLCTKAV
CHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHCCC
DPHGMVMHVSSFSKNLAPGYRVGWVAAGRFAERVQRQKFSTTLATTIPVQIALAEYLKHG
CCCCEEEEECHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYENHLRHLRRKLAEQEAALAAAIEPNFPEGTRLARPDGGYFLWLELPPQIDTLVLHQRT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHH
LARGISTAPGPIFSAKREFTHHLRLNFGHSDSQRQQDAMVTLGQLIAEQL
HHHCCCCCCCCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]