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The map label for this gene is lpxH [H]

Identifier: 74317923

GI number: 74317923

Start: 2001387

End: 2002130

Strand: Direct

Name: lpxH [H]

Synonym: Tbd_1905

Alternate gene names: 74317923

Gene position: 2001387-2002130 (Clockwise)

Preceding gene: 74317922

Following gene: 74317944

Centisome position: 68.78

GC content: 69.76

Gene sequence:

>744_bases
GTGGGCGCAAAACCGGGTGCGGGCCGGGCCTTCTTCGTCGCCGACCTCCATCTGACCGACGACCGCCCGCGCGCGACCGA
GCGTTTCTTCCGTTTTCTCGAGGAAGAGGTTGCGGGCGCGGATGCGCTCTACATCCTCGGCGACCTGTTCGAGGCCTGGA
TCGGCGACGATCACGACGAGCAGGTCGCGACGGCGACCGCGCAGCACCTGAAGGCGCTCGCCGAAGCCGGCACCCGCGTA
TATTTCATGCACGGCAACCGTGATTTCATGCTGGCCGGCCGCTACGCCGGGCAGGCCGGCATGACGCTGTGCGCCGACCC
CACGCGGATCGACCTCTACGGCACGCCAACACTGCTCACGCACGGGGACACGCTTTGCACCGACGATACGGCCTATCAGG
CGTTCCGCCGGCGCGTGCGTCATCCGCTTACGCTCGCGCTGCTGCGACGGCTGCCGCGCGGGCTGCGCAACCGTCTCGCC
CGCGGCGCCCGTGCCGGGAGCCAGGCGGCGAAAGCCCGCAAGCCGGTGCAGACCATGGACGTCAATGCCGACGCCGTCGT
CGACGCATTGCGCAGCCACGCGGTCACGCGCCTGATCCACGGCCACACCCATCGCCCCGCTCGGCACGTGCACGAGCTCG
ACGGCCAGCAGTGCGAGCGCTGGGTGCTTCCCGACTGGTACGCGCGCTGGGGCTACGTCGTCTGCGACGCGGCCAGATGC
ACGCTGCGGGTCGAGGACTTATGA

Upstream 100 bases:

>100_bases
ACAAGATCAAGAAGGTCAAGACCGGAAGCCGCGGCGGCCACCAGGACGTGCCGCTGGAAGACGTCGTCATCACGAAGGCC
GAAATCATCTGATTTCGGCC

Downstream 100 bases:

>100_bases
CGGCGCGTTGACCGCCGTCAAGCCCGGCGGGACGCGGAACAGTTCCGGCGCGCGGGGCAGCTTCGATTCGCTTTCGAATC
GCCGCGTGCGCCCGCTGAAC

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MGAKPGAGRAFFVADLHLTDDRPRATERFFRFLEEEVAGADALYILGDLFEAWIGDDHDEQVATATAQHLKALAEAGTRV
YFMHGNRDFMLAGRYAGQAGMTLCADPTRIDLYGTPTLLTHGDTLCTDDTAYQAFRRRVRHPLTLALLRRLPRGLRNRLA
RGARAGSQAAKARKPVQTMDVNADAVVDALRSHAVTRLIHGHTHRPARHVHELDGQQCERWVLPDWYARWGYVVCDAARC
TLRVEDL

Sequences:

>Translated_247_residues
MGAKPGAGRAFFVADLHLTDDRPRATERFFRFLEEEVAGADALYILGDLFEAWIGDDHDEQVATATAQHLKALAEAGTRV
YFMHGNRDFMLAGRYAGQAGMTLCADPTRIDLYGTPTLLTHGDTLCTDDTAYQAFRRRVRHPLTLALLRRLPRGLRNRLA
RGARAGSQAAKARKPVQTMDVNADAVVDALRSHAVTRLIHGHTHRPARHVHELDGQQCERWVLPDWYARWGYVVCDAARC
TLRVEDL
>Mature_246_residues
GAKPGAGRAFFVADLHLTDDRPRATERFFRFLEEEVAGADALYILGDLFEAWIGDDHDEQVATATAQHLKALAEAGTRVY
FMHGNRDFMLAGRYAGQAGMTLCADPTRIDLYGTPTLLTHGDTLCTDDTAYQAFRRRVRHPLTLALLRRLPRGLRNRLAR
GARAGSQAAKARKPVQTMDVNADAVVDALRSHAVTRLIHGHTHRPARHVHELDGQQCERWVLPDWYARWGYVVCDAARCT
LRVEDL

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=229, Percent_Identity=48.9082969432314, Blast_Score=208, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010138 [H]

Pfam domain/function: NA

EC number: 3.6.1.-

Molecular weight: Translated: 27671; Mature: 27540

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAKPGAGRAFFVADLHLTDDRPRATERFFRFLEEEVAGADALYILGDLFEAWIGDDHDE
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
QVATATAQHLKALAEAGTRVYFMHGNRDFMLAGRYAGQAGMTLCADPTRIDLYGTPTLLT
HHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCEEECCCCEEEEECCCEEEE
HGDTLCTDDTAYQAFRRRVRHPLTLALLRRLPRGLRNRLARGARAGSQAAKARKPVQTMD
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHCC
VNADAVVDALRSHAVTRLIHGHTHRPARHVHELDGQQCERWVLPDWYARWGYVVCDAARC
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHCCCCHHHHHCCCEEEECCEE
TLRVEDL
EEEEECC
>Mature Secondary Structure 
GAKPGAGRAFFVADLHLTDDRPRATERFFRFLEEEVAGADALYILGDLFEAWIGDDHDE
CCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
QVATATAQHLKALAEAGTRVYFMHGNRDFMLAGRYAGQAGMTLCADPTRIDLYGTPTLLT
HHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCEEECCCCEEEEECCCEEEE
HGDTLCTDDTAYQAFRRRVRHPLTLALLRRLPRGLRNRLARGARAGSQAAKARKPVQTMD
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHCC
VNADAVVDALRSHAVTRLIHGHTHRPARHVHELDGQQCERWVLPDWYARWGYVVCDAARC
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHCCCCHHHHHCCCEEEECCEE
TLRVEDL
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA