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The map label for this gene is degP [H]

Identifier: 74317852

GI number: 74317852

Start: 1932987

End: 1934177

Strand: Direct

Name: degP [H]

Synonym: Tbd_1834

Alternate gene names: 74317852

Gene position: 1932987-1934177 (Clockwise)

Preceding gene: 74317841

Following gene: 74317855

Centisome position: 66.43

GC content: 66.58

Gene sequence:

>1191_bases
ATGCATATACGGAAATTCTGGTTGCTTTTTGCCCAGTCGGTGACGGTCGCACTCGGCGCGCTCGTCGTCGTCGCGCTCTT
CAAACCCGATTTGCTGCAATGGCGTGCCCAGACCCCGAATCTCACGATCCAGCAGGCCCGTCCCCAAGGCGGCGGCACGG
TCACCGTCGCGCCCAATGAGTCCTTCGCGCTGGCGGCGCAAAAGGTCATTCCATCGGTGGTCAACGTGTTCACGCAGCAA
AAGGTCCGCAACCCTGCGCATCCTGCGATGCAGGATCCGATTTTTCGCTACTTCTTCGGTGATCGGCTCGACGCGCGGCC
GCGCGAGGTGTCCAACCTCGGCTCGGGGGTCATCGTCACGACCAACGGCTACATCCTGACCAACCACCACGTCGTCGATG
CCGCGGACCAGATCGAGGTCGCCCTTGCCGACGGCAAGACCGTGCCGGCGCGGGTGATCGGCGCGGACCCCGAGACCGAC
CTCGCCGTCCTCAAGATCGATGCGGAAAAGCTGCCGGCGATCACCTTCGCCAACGCCGACAGCCTCAAGGTCGGCGACTG
GGTGCTCGCGGTCGGCAACCCCTTCGGCGTTGGCCAGACCGTGACCGCGGGCATCGTGAGTGCACTCGGCCGGACCCGGT
TGGGCATCAATACTTTCGAGAACTTCATTCAGACCGACGCGGCGATCAACCCGGGCAACTCGGGCGGCGCGCTCGTCGAC
TCGGCGGGTAACCTGGTCGGGGTGAACAGCGCGATCTACTCGCGCACGGGCGGCTCGCAAGGCATCGGCTTCGCGATTCC
GGTCAGCATCGCCCGTCAGGTGATGGAACAGATCATCAAGTCCGGCAGCGTGACCCGCGGCTGGGTAGGGGTCGAGGTGC
AGGACCTGACGCCGGAGCTCGCCGAGTCGTTCAACCTGCCCGACGTCAACGGCGCCTTGATCGCCGGGGTTCTCAAGGGC
GGGCCTGCCGATACCGGCGGGGTGCGGCCCGGCGACATTCTGCTCGCGGTCAACGGCCGCAGGGTGACCGACTCGGCGTC
CCTGCTCAACCTGATCGCGGAACTCACGCCCGGCCAGAGCGCGCGACTGACCGTCGCCCGCAAGCAGCGCTCGCTCGATC
TCAAGGTCGAGGTGGGACGGCGGCCGCTGCAGCGCGCCCTGCCGATGCCGCCCGAGCCGGCGCTCGAATAA

Upstream 100 bases:

>100_bases
CGGCTCCGAAAGCCCGCCGTAGCGCCCACGCAACGGTTTTGCGCCTGCGCTATACTGCGCGACTGGCAAATTCATGCCAA
GTCTCTGAATTTAATAAGAT

Downstream 100 bases:

>100_bases
CGTACGCTGGATGCACCGCTCAGCGGTAAGGATGGAACGGGAAGGCGCTTAGACCCGGATGTAGGTCCACCCCTGCTGCA
GGCGGGTGACGATTTCGCCG

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MHIRKFWLLFAQSVTVALGALVVVALFKPDLLQWRAQTPNLTIQQARPQGGGTVTVAPNESFALAAQKVIPSVVNVFTQQ
KVRNPAHPAMQDPIFRYFFGDRLDARPREVSNLGSGVIVTTNGYILTNHHVVDAADQIEVALADGKTVPARVIGADPETD
LAVLKIDAEKLPAITFANADSLKVGDWVLAVGNPFGVGQTVTAGIVSALGRTRLGINTFENFIQTDAAINPGNSGGALVD
SAGNLVGVNSAIYSRTGGSQGIGFAIPVSIARQVMEQIIKSGSVTRGWVGVEVQDLTPELAESFNLPDVNGALIAGVLKG
GPADTGGVRPGDILLAVNGRRVTDSASLLNLIAELTPGQSARLTVARKQRSLDLKVEVGRRPLQRALPMPPEPALE

Sequences:

>Translated_396_residues
MHIRKFWLLFAQSVTVALGALVVVALFKPDLLQWRAQTPNLTIQQARPQGGGTVTVAPNESFALAAQKVIPSVVNVFTQQ
KVRNPAHPAMQDPIFRYFFGDRLDARPREVSNLGSGVIVTTNGYILTNHHVVDAADQIEVALADGKTVPARVIGADPETD
LAVLKIDAEKLPAITFANADSLKVGDWVLAVGNPFGVGQTVTAGIVSALGRTRLGINTFENFIQTDAAINPGNSGGALVD
SAGNLVGVNSAIYSRTGGSQGIGFAIPVSIARQVMEQIIKSGSVTRGWVGVEVQDLTPELAESFNLPDVNGALIAGVLKG
GPADTGGVRPGDILLAVNGRRVTDSASLLNLIAELTPGQSARLTVARKQRSLDLKVEVGRRPLQRALPMPPEPALE
>Mature_396_residues
MHIRKFWLLFAQSVTVALGALVVVALFKPDLLQWRAQTPNLTIQQARPQGGGTVTVAPNESFALAAQKVIPSVVNVFTQQ
KVRNPAHPAMQDPIFRYFFGDRLDARPREVSNLGSGVIVTTNGYILTNHHVVDAADQIEVALADGKTVPARVIGADPETD
LAVLKIDAEKLPAITFANADSLKVGDWVLAVGNPFGVGQTVTAGIVSALGRTRLGINTFENFIQTDAAINPGNSGGALVD
SAGNLVGVNSAIYSRTGGSQGIGFAIPVSIARQVMEQIIKSGSVTRGWVGVEVQDLTPELAESFNLPDVNGALIAGVLKG
GPADTGGVRPGDILLAVNGRRVTDSASLLNLIAELTPGQSARLTVARKQRSLDLKVEVGRRPLQRALPMPPEPALE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=254, Percent_Identity=35.0393700787402, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI24308541, Length=359, Percent_Identity=31.4763231197772, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=302, Percent_Identity=35.4304635761589, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI22129776, Length=262, Percent_Identity=34.3511450381679, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1789629, Length=344, Percent_Identity=42.7325581395349, Blast_Score=257, Evalue=7e-70,
Organism=Escherichia coli, GI1786356, Length=345, Percent_Identity=39.4202898550725, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789630, Length=326, Percent_Identity=37.7300613496933, Blast_Score=214, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24646839, Length=280, Percent_Identity=35.3571428571429, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41754; Mature: 41754

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIRKFWLLFAQSVTVALGALVVVALFKPDLLQWRAQTPNLTIQQARPQGGGTVTVAPNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCCCEEEECCCC
SFALAAQKVIPSVVNVFTQQKVRNPAHPAMQDPIFRYFFGDRLDARPREVSNLGSGVIVT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHCCCCCCCCHHHHHCCCCEEEE
TNGYILTNHHVVDAADQIEVALADGKTVPARVIGADPETDLAVLKIDAEKLPAITFANAD
ECCEEEECCEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECHHHCCEEEECCCC
SLKVGDWVLAVGNPFGVGQTVTAGIVSALGRTRLGINTFENFIQTDAAINPGNSGGALVD
CEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEE
SAGNLVGVNSAIYSRTGGSQGIGFAIPVSIARQVMEQIIKSGSVTRGWVGVEVQDLTPEL
CCCCEEECCHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHH
AESFNLPDVNGALIAGVLKGGPADTGGVRPGDILLAVNGRRVTDSASLLNLIAELTPGQS
HHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCEECCHHHHHHHHHHCCCCCC
ARLTVARKQRSLDLKVEVGRRPLQRALPMPPEPALE
CEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHIRKFWLLFAQSVTVALGALVVVALFKPDLLQWRAQTPNLTIQQARPQGGGTVTVAPNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEECCCCCCCEEEECCCC
SFALAAQKVIPSVVNVFTQQKVRNPAHPAMQDPIFRYFFGDRLDARPREVSNLGSGVIVT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHCCCCCCCCHHHHHCCCCEEEE
TNGYILTNHHVVDAADQIEVALADGKTVPARVIGADPETDLAVLKIDAEKLPAITFANAD
ECCEEEECCEEECCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECHHHCCEEEECCCC
SLKVGDWVLAVGNPFGVGQTVTAGIVSALGRTRLGINTFENFIQTDAAINPGNSGGALVD
CEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEE
SAGNLVGVNSAIYSRTGGSQGIGFAIPVSIARQVMEQIIKSGSVTRGWVGVEVQDLTPEL
CCCCEEECCHHHHCCCCCCCCCCEEECHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHH
AESFNLPDVNGALIAGVLKGGPADTGGVRPGDILLAVNGRRVTDSASLLNLIAELTPGQS
HHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCEECCHHHHHHHHHHCCCCCC
ARLTVARKQRSLDLKVEVGRRPLQRALPMPPEPALE
CEEEEEECCCCCEEEEECCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]