Click here to switch to the map view.

The map label for this gene is yciK [H]

Identifier: 74317717

GI number: 74317717

Start: 1790529

End: 1791272

Strand: Direct

Name: yciK [H]

Synonym: Tbd_1699

Alternate gene names: 74317717

Gene position: 1790529-1791272 (Clockwise)

Preceding gene: 74317716

Following gene: 74317718

Centisome position: 61.53

GC content: 68.82

Gene sequence:

>744_bases
ATGAAAAACTACCTTCCTCGTCCCGACCTGCTTGCCGGTCGCGTCATTCTCGTCACCGGTGCGAGCGCCGGTCTCGGCCG
CGCGGCCAGCCTGGCCTTCGCGCGCCACGGCGCGACGGTCGCGCTGCTCGCGCGCAACGAAGCCAAGCTCGAAGCGGTGT
ACGACGAGATCGTCGCCGCCGGCGGCCCGGAGCCGGCGATGTTTCCCTTCGATCTCGCCGTCGCGGACGATCGCAGCCTC
GAGAACCTGGCCGGAACGCTCGCGCACCACCTCGGCCGGCTCGACGGTCTGTTGCACAGCGCCCACCAGTTCTTCAGTCT
CACGCCGCTCAGCCTGCAGACGCTCGAGCAGTGGCAGACCCTCATGCGCGTCAATCTGATCGCGCCCTTCGCCCTCACCC
GCGCCGTGATGCCCTTGCTGCAGCAGGCGCCGGACGCGTCGGTCGTCTTTACCGGCGAGACCCACGGCCATTCGCCGAGT
GCATACTGGGGCGGCTACGCCGTCGCGAAGTCGGGGCTGGAGACGCTGACGCGCATCTGGTCGGACGAGCTCGCAAGCAG
CGAGAGCCTGCGCATCAATACGCTGATTCCCGGCCAGGTCGCGACCACCTTGCGCGCGCGCACCTACCCGGGCGTCGCCG
CCGAAACCCTGCCGAGCCCGGAAGCTGTGATGCCGTGGTACCTCTTCCTGATGGGCGAAGACGGCCGCGAGGTCCGCGGC
CAGACGGTGGAATGCCACACCTGA

Upstream 100 bases:

>100_bases
TTTTCCTCGCTGGCGACTACACCGCCGGCCCCTATCCCGCGACGCTCGAAAGCGCAACCCAGAGCGGGGTACAATCGGCC
GCCTCTCTTCTCGAAACGCT

Downstream 100 bases:

>100_bases
GCCGACCTTCCTGATGAACATCGGCCGTTACGAAATCATCGACGGAATCGGCCAGGGTGCGATGGGCACTGTTTATCGGG
CGCGCGACCCGCTCATCGAG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKNYLPRPDLLAGRVILVTGASAGLGRAASLAFARHGATVALLARNEAKLEAVYDEIVAAGGPEPAMFPFDLAVADDRSL
ENLAGTLAHHLGRLDGLLHSAHQFFSLTPLSLQTLEQWQTLMRVNLIAPFALTRAVMPLLQQAPDASVVFTGETHGHSPS
AYWGGYAVAKSGLETLTRIWSDELASSESLRINTLIPGQVATTLRARTYPGVAAETLPSPEAVMPWYLFLMGEDGREVRG
QTVECHT

Sequences:

>Translated_247_residues
MKNYLPRPDLLAGRVILVTGASAGLGRAASLAFARHGATVALLARNEAKLEAVYDEIVAAGGPEPAMFPFDLAVADDRSL
ENLAGTLAHHLGRLDGLLHSAHQFFSLTPLSLQTLEQWQTLMRVNLIAPFALTRAVMPLLQQAPDASVVFTGETHGHSPS
AYWGGYAVAKSGLETLTRIWSDELASSESLRINTLIPGQVATTLRARTYPGVAAETLPSPEAVMPWYLFLMGEDGREVRG
QTVECHT
>Mature_247_residues
MKNYLPRPDLLAGRVILVTGASAGLGRAASLAFARHGATVALLARNEAKLEAVYDEIVAAGGPEPAMFPFDLAVADDRSL
ENLAGTLAHHLGRLDGLLHSAHQFFSLTPLSLQTLEQWQTLMRVNLIAPFALTRAVMPLLQQAPDASVVFTGETHGHSPS
AYWGGYAVAKSGLETLTRIWSDELASSESLRINTLIPGQVATTLRARTYPGVAAETLPSPEAVMPWYLFLMGEDGREVRG
QTVECHT

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=28.2868525896414, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI5031737, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=24.4186046511628, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4504505, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=24.6153846153846, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787526, Length=243, Percent_Identity=40.7407407407407, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.1338582677165, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=26.0330578512397, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787820, Length=215, Percent_Identity=23.7209302325581, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=204, Percent_Identity=30.3921568627451, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=202, Percent_Identity=29.7029702970297, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=245, Percent_Identity=26.1224489795918, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=195, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=240, Percent_Identity=28.75, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=220, Percent_Identity=28.6363636363636, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=214, Percent_Identity=26.6355140186916, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=238, Percent_Identity=24.3697478991597, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=27.1794871794872, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=24.8730964467005, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=25.3012048192771, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=28.7081339712919, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=25.2475247524752, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=222, Percent_Identity=26.5765765765766, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=23.5897435897436, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=254, Percent_Identity=24.0157480314961, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=24.0458015267176, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=24.5762711864407, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=206, Percent_Identity=31.5533980582524, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=31.2820512820513, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=199, Percent_Identity=33.1658291457286, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=24.5901639344262, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26569; Mature: 26569

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYLPRPDLLAGRVILVTGASAGLGRAASLAFARHGATVALLARNEAKLEAVYDEIVAA
CCCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC
GGPEPAMFPFDLAVADDRSLENLAGTLAHHLGRLDGLLHSAHQFFSLTPLSLQTLEQWQT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LMRVNLIAPFALTRAVMPLLQQAPDASVVFTGETHGHSPSAYWGGYAVAKSGLETLTRIW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SDELASSESLRINTLIPGQVATTLRARTYPGVAAETLPSPEAVMPWYLFLMGEDGREVRG
HHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCHHCCEEEEEECCCCHHHCC
QTVECHT
CEEECCC
>Mature Secondary Structure
MKNYLPRPDLLAGRVILVTGASAGLGRAASLAFARHGATVALLARNEAKLEAVYDEIVAA
CCCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHC
GGPEPAMFPFDLAVADDRSLENLAGTLAHHLGRLDGLLHSAHQFFSLTPLSLQTLEQWQT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LMRVNLIAPFALTRAVMPLLQQAPDASVVFTGETHGHSPSAYWGGYAVAKSGLETLTRIW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SDELASSESLRINTLIPGQVATTLRARTYPGVAAETLPSPEAVMPWYLFLMGEDGREVRG
HHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCHHCCEEEEEECCCCHHHCC
QTVECHT
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]