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The map label for this gene is aer [H]

Identifier: 74317636

GI number: 74317636

Start: 1699711

End: 1701384

Strand: Reverse

Name: aer [H]

Synonym: Tbd_1618

Alternate gene names: 74317636

Gene position: 1701384-1699711 (Counterclockwise)

Preceding gene: 74317637

Following gene: 74317635

Centisome position: 58.47

GC content: 65.17

Gene sequence:

>1674_bases
ATGCGATCCAATCAACCCGTAACCAACGTCGAATACGTCCTGAAAGATACCGAAACCGTGGTGTCGAAAACGGACCTGCG
CGGCAACATCACCTACGTCAACCAGGATTTCGTCGACGTCAGCGGCTTCAGCGAAGCCGAACTGATCGGCGCGCCGCAGA
ACATCGTGCGTCACCCCGACATGCCCGAGGAGGCTTTCGCCGACCTCTGGCGGACGCTCCAGAGCGGCAAGGTGTGGAGC
GGCCTGGTCAAGAATCGCTGCAAGAACGGCGACTACTACTGGGTCGATGCCGATGTGGCACCGCTCATCGAGAATGGAAA
GACCGTCGGCTATGCTTCGATCCGCAGCAAGCCGGACCGTGAGCAGGTCAAGGAAGCCGAGCGGGTGTATCGCGCTGTGA
AGGCGGGCGACAAGGGCCTTGGGATCGTCGAGGGCAAGGCGATCAAGTGCTCGTCGCTCGACCGCTGCTTCGCGCGCCGT
GCGCCGGCGCTCAAGACCCTGCTTGCGATCGCTTCGTCGTCGATGGCGCTCATTTTCGTGGTGATGGCGGTCCTGGCATG
GCTTGCGACGACCGAGACCAACGGCCAGTTCACAGGCTGGCTGATGGGGATCGCAGGGCTCGGCGTGCCGCTCGCCGCCT
TGTTCGCAGTCCTGTCGTATCGCAGCGTCGTCATACCGCTCGACCGCGTTCGCGCCGACATCGAGCGCATGAGCGCGGGC
GACCTCACCGGCCGCATCGTCGCGGGGGGGGCTGACGAACTCGTCAGACTGATGCAGTCGCTGCGCGTGCTGCAGATCAA
CATGAAGCTCCTGATCGGCCAGATCAAGCAGAGCACAGACCTCGTCGGCAACGGCGCGGCCGAAATCGCCAAAGGCAACG
CGGATCTGTCGGCGCGGACCGAATCGCAGGCGTCGAGTCTCGAGGAGACCGCAAGCTCGCTCGAGGAGCTGACCGGCACG
GTCAAGCAGAACGCCGAGGGGACGCGTCACGCGAGCCAGCTCGTCACCTCTACCGCACAGATCGCGGCAAACGGCGGCGA
GGTTGTCGGCAAGGTGATCACCACCATGGGCTCGATCAAGGAAAGCTCGCGCAAGATCTCCGACATCATTGGCGTCATCG
ATGGGATCGCCTTCCAGACCAACATCCTCGCCTTGAACGCAGCCGTCGAAGCAGCGCGCGCGGGCGAGCAGGGACGAGGC
TTCGCCGTCGTCGCGACCGAGGTGCGCAACCTGGCGCAGCGCAGCGCGGGTGCGGCCAAGGAGATCAAGACCTTGATCAA
CGACTCGGTCGCCCAGGTCGACGCCGGCAGGAAGCTCGTCGACGAGGCGGGCGACGCGATGGACGACATCGTGACCTCGG
TGCAACTGGTCGCCGACATCATTGCCGGCACGGCGAGTGCGAGCCAGGAGCAGAGTACCGGGATCGAGCAGGTCAACCAG
GCCGTGGCGCAGATGGACGAACTCACCCAGCAGAACGCGGCGCTGGTCGAACAGGTCGCGGCCGCGTCCGAGACCCTGCA
GGATCAGGCGGTCAAACTCGCGGCCATCGTCGACACGTTCAAACTCGTGAGCGGCCGGGACGCGGGACGCCGCCCCGGCG
CAGGCCGTGCCCTCGCATCCGGAACGAACACGGCGCTTTCGGGCGGAGCGAGCGGCGCAATGCAAGCGGCGTAG

Upstream 100 bases:

>100_bases
CCGATATGGAGAGTGAGGGCAAGCGATCGCTCAGTCGCGAGCGGGTCGCAGATCAATCAAAAAATAAGCGTTAACTCTCC
CCTGCGGAAGAAAGAAAACG

Downstream 100 bases:

>100_bases
CGAGTCGAGCCCTGGCCGCGACCCGCGGAGGGCGCGGCCCGACCGGGCCGTTGTCCCCTCCGCCCCACGCAATTCCCGTT
CCATCTTCGGTGGCGCTGAT

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRSNQPVTNVEYVLKDTETVVSKTDLRGNITYVNQDFVDVSGFSEAELIGAPQNIVRHPDMPEEAFADLWRTLQSGKVWS
GLVKNRCKNGDYYWVDADVAPLIENGKTVGYASIRSKPDREQVKEAERVYRAVKAGDKGLGIVEGKAIKCSSLDRCFARR
APALKTLLAIASSSMALIFVVMAVLAWLATTETNGQFTGWLMGIAGLGVPLAALFAVLSYRSVVIPLDRVRADIERMSAG
DLTGRIVAGGADELVRLMQSLRVLQINMKLLIGQIKQSTDLVGNGAAEIAKGNADLSARTESQASSLEETASSLEELTGT
VKQNAEGTRHASQLVTSTAQIAANGGEVVGKVITTMGSIKESSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRG
FAVVATEVRNLAQRSAGAAKEIKTLINDSVAQVDAGRKLVDEAGDAMDDIVTSVQLVADIIAGTASASQEQSTGIEQVNQ
AVAQMDELTQQNAALVEQVAAASETLQDQAVKLAAIVDTFKLVSGRDAGRRPGAGRALASGTNTALSGGASGAMQAA

Sequences:

>Translated_557_residues
MRSNQPVTNVEYVLKDTETVVSKTDLRGNITYVNQDFVDVSGFSEAELIGAPQNIVRHPDMPEEAFADLWRTLQSGKVWS
GLVKNRCKNGDYYWVDADVAPLIENGKTVGYASIRSKPDREQVKEAERVYRAVKAGDKGLGIVEGKAIKCSSLDRCFARR
APALKTLLAIASSSMALIFVVMAVLAWLATTETNGQFTGWLMGIAGLGVPLAALFAVLSYRSVVIPLDRVRADIERMSAG
DLTGRIVAGGADELVRLMQSLRVLQINMKLLIGQIKQSTDLVGNGAAEIAKGNADLSARTESQASSLEETASSLEELTGT
VKQNAEGTRHASQLVTSTAQIAANGGEVVGKVITTMGSIKESSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRG
FAVVATEVRNLAQRSAGAAKEIKTLINDSVAQVDAGRKLVDEAGDAMDDIVTSVQLVADIIAGTASASQEQSTGIEQVNQ
AVAQMDELTQQNAALVEQVAAASETLQDQAVKLAAIVDTFKLVSGRDAGRRPGAGRALASGTNTALSGGASGAMQAA
>Mature_557_residues
MRSNQPVTNVEYVLKDTETVVSKTDLRGNITYVNQDFVDVSGFSEAELIGAPQNIVRHPDMPEEAFADLWRTLQSGKVWS
GLVKNRCKNGDYYWVDADVAPLIENGKTVGYASIRSKPDREQVKEAERVYRAVKAGDKGLGIVEGKAIKCSSLDRCFARR
APALKTLLAIASSSMALIFVVMAVLAWLATTETNGQFTGWLMGIAGLGVPLAALFAVLSYRSVVIPLDRVRADIERMSAG
DLTGRIVAGGADELVRLMQSLRVLQINMKLLIGQIKQSTDLVGNGAAEIAKGNADLSARTESQASSLEETASSLEELTGT
VKQNAEGTRHASQLVTSTAQIAANGGEVVGKVITTMGSIKESSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRG
FAVVATEVRNLAQRSAGAAKEIKTLINDSVAQVDAGRKLVDEAGDAMDDIVTSVQLVADIIAGTASASQEQSTGIEQVNQ
AVAQMDELTQQNAALVEQVAAASETLQDQAVKLAAIVDTFKLVSGRDAGRRPGAGRALASGTNTALSGGASGAMQAA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=514, Percent_Identity=37.5486381322957, Blast_Score=336, Evalue=3e-93,
Organism=Escherichia coli, GI2367378, Length=309, Percent_Identity=54.0453074433657, Blast_Score=294, Evalue=9e-81,
Organism=Escherichia coli, GI1787690, Length=343, Percent_Identity=47.2303206997085, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=54.9668874172185, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1788194, Length=302, Percent_Identity=53.3112582781457, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 58604; Mature: 58604

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSNQPVTNVEYVLKDTETVVSKTDLRGNITYVNQDFVDVSGFSEAELIGAPQNIVRHPD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHCCCCHHHHCCCC
MPEEAFADLWRTLQSGKVWSGLVKNRCKNGDYYWVDADVAPLIENGKTVGYASIRSKPDR
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCEEEEHHHCCCCCH
EQVKEAERVYRAVKAGDKGLGIVEGKAIKCSSLDRCFARRAPALKTLLAIASSSMALIFV
HHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHH
VMAVLAWLATTETNGQFTGWLMGIAGLGVPLAALFAVLSYRSVVIPLDRVRADIERMSAG
HHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCC
DLTGRIVAGGADELVRLMQSLRVLQINMKLLIGQIKQSTDLVGNGAAEIAKGNADLSART
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
ESQASSLEETASSLEELTGTVKQNAEGTRHASQLVTSTAQIAANGGEVVGKVITTMGSIK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ESSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRNLAQRSAGAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHH
EIKTLINDSVAQVDAGRKLVDEAGDAMDDIVTSVQLVADIIAGTASASQEQSTGIEQVNQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHH
AVAQMDELTQQNAALVEQVAAASETLQDQAVKLAAIVDTFKLVSGRDAGRRPGAGRALAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCC
GTNTALSGGASGAMQAA
CCCHHCCCCCCCCCCCC
>Mature Secondary Structure
MRSNQPVTNVEYVLKDTETVVSKTDLRGNITYVNQDFVDVSGFSEAELIGAPQNIVRHPD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCHHHCCCCHHHHCCCC
MPEEAFADLWRTLQSGKVWSGLVKNRCKNGDYYWVDADVAPLIENGKTVGYASIRSKPDR
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCEEEEHHHCCCCCH
EQVKEAERVYRAVKAGDKGLGIVEGKAIKCSSLDRCFARRAPALKTLLAIASSSMALIFV
HHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHH
VMAVLAWLATTETNGQFTGWLMGIAGLGVPLAALFAVLSYRSVVIPLDRVRADIERMSAG
HHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCC
DLTGRIVAGGADELVRLMQSLRVLQINMKLLIGQIKQSTDLVGNGAAEIAKGNADLSART
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
ESQASSLEETASSLEELTGTVKQNAEGTRHASQLVTSTAQIAANGGEVVGKVITTMGSIK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ESSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRNLAQRSAGAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHH
EIKTLINDSVAQVDAGRKLVDEAGDAMDDIVTSVQLVADIIAGTASASQEQSTGIEQVNQ
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHH
AVAQMDELTQQNAALVEQVAAASETLQDQAVKLAAIVDTFKLVSGRDAGRRPGAGRALAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCC
GTNTALSGGASGAMQAA
CCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]