Click here to switch to the map view.

The map label for this gene is fliI [H]

Identifier: 74317621

GI number: 74317621

Start: 1688374

End: 1689780

Strand: Direct

Name: fliI [H]

Synonym: Tbd_1603

Alternate gene names: 74317621

Gene position: 1688374-1689780 (Clockwise)

Preceding gene: 74317620

Following gene: 74317622

Centisome position: 58.02

GC content: 68.59

Gene sequence:

>1407_bases
ATGAACACCCACGTGCACGCCGCCCGCTGGCAAGCCTACCTGCAAGACTGCACCGAACTGCTCGCGATCGCCGAGCCGAT
GCGGCTGTCCGGGCGGATTACGCGCGTCGCGGGACTCGTGATGGAGGCGGTGGGCTTGAAGCTTCCGGTCGGCAGCGCCT
GTACCGTGCCGCTGCCCAACGGCTCGCACCTCGAAGCCGAGGTCGTCGGGTTCGAAGGCGAGCGCTTGTTCCTGATGCCG
CAGAGCGACGTCGAGGGCATCGTCCCGGGCGCCCGGGTGTTTCCGGTCGAAGTCATCCCCACTTTGCCTGGCTTGGGCCA
GGTCAATCATCCCCGGCGACGCCCGAGCGATCGCACGCGCCACCTGCCCGTGGGCGAGGTCCTGCTGGGCCGCGTGCTCG
ACAGCAACGGGCGCCCACTCGATGGCCTCGGCTCGGTCCATACCTCGGCGACAGCACCGCTCAACAACCGCGCGGCGAAC
CCGCTCTCGCGCGCCCCGATCAGCGAGATCCTCGACGTCGGCGTGCGCGCGATCAACAGCATGCTGACGATCGGTCGCGG
CCAGCGCATGGGCCTCTTCGCCGGCTCGGGCGTCGGCAAGAGCGTGCTACTCGGCATGATGGCGCGCTACACCAGCGCCG
ACGTGATCGTCGTCGGCCTGATCGGCGAACGCGGCCGCGAAGTAAAGGAATTCATCGAGCAAATCCTCGGCGAAGAAGGC
CTGGCCCGCGCGGTCGTCGTCGCCGCCCCGGCCGACACGCCGCCGCTCATGCGTCTGCAAGGGGCGGCCTACGCCACGGC
GATCGCCGAGCATTTCCGCGACGAGGGCAAGAACGTCTTGCTGATCATGGATTCGCTGACGAGATATGCCATGGCGCAGC
GCGAAATCGCGCTCGCGATCGGCGAGCCGCCGGCGACAAAGGGCTATCCGCCGTCGGTTTTCGCCAAGCTGCCGGCGCTG
GTCGAACGCGCCGGCAACGGCAAGCCGGGCGGCGGGTCGATCACTGCCTTTTACACCGTGCTCACCGAGGGCGACGACCA
GCAGGACCCGATCGCCGACTCGGCGCGCGCGATCCTCGACGGCCATATCGTGCTGTCGCGCGACCTCGCCGAAAGCGGCC
ACTACCCGGCGATCGACATCGAGCAATCGATCAGCCGCGCGATGCACGGCATCACGAGCGCGGCGCACCAGCAGATGGCG
CGCCGCCTGAAGAAGCTCTATTCGCGTTACGCGCGCAGCCGCGACCTGATCAACGTCGGCGCCTATGCCCCCGGGACCGA
TCCGCTGCTCGACGAGGCGATCCGCCTGCAGGAGGGCATCGAGGCCTTCCTCCAGCAGAACATCCCCGAACGCGCGGGCG
TCGAGGAGAGCCTGGCCGCGTTGTCCACCCTCTTCCCGTCCACCTGA

Upstream 100 bases:

>100_bases
ACCGCCAACAACCAGATCGACGCCGCATTGTCCACGCGCTGGCATCGCCTCGCTGCGGCGCTCGGCAAGGATTCGGGCTG
GCTCGCCTGACCGACGAAAG

Downstream 100 bases:

>100_bases
ACCGGAACACATCGCTGAATGGCCGCACCCTCCGCACTCGATACGCTGATCGACCTCGCCATCAAGGAAACCGACGAGGC
AGCCAAACGGCTCGCCGCCG

Product: flagellar biosynthesis/type III secretory pathway ATPase FliI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPNGSHLEAEVVGFEGERLFLMP
QSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTRHLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAAN
PLSRAPISEILDVGVRAINSMLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPAL
VERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMA
RRLKKLYSRYARSRDLINVGAYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST

Sequences:

>Translated_468_residues
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPNGSHLEAEVVGFEGERLFLMP
QSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTRHLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAAN
PLSRAPISEILDVGVRAINSMLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPAL
VERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMA
RRLKKLYSRYARSRDLINVGAYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST
>Mature_468_residues
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPNGSHLEAEVVGFEGERLFLMP
QSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTRHLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAAN
PLSRAPISEILDVGVRAINSMLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPAL
VERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMA
RRLKKLYSRYARSRDLINVGAYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=340, Percent_Identity=30.8823529411765, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI50345984, Length=355, Percent_Identity=29.8591549295775, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4757810, Length=355, Percent_Identity=29.8591549295775, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI19913426, Length=372, Percent_Identity=27.6881720430108, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI19913428, Length=372, Percent_Identity=27.6881720430108, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913424, Length=315, Percent_Identity=27.3015873015873, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1788251, Length=444, Percent_Identity=66.8918918918919, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1790170, Length=333, Percent_Identity=31.2312312312312, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1790172, Length=340, Percent_Identity=27.6470588235294, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790217, Length=240, Percent_Identity=30, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71988063, Length=355, Percent_Identity=30.7042253521127, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71988080, Length=355, Percent_Identity=30.7042253521127, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI25144756, Length=341, Percent_Identity=29.9120234604106, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI71988074, Length=335, Percent_Identity=29.5522388059701, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17570191, Length=369, Percent_Identity=28.1842818428184, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=372, Percent_Identity=27.6881720430108, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17565854, Length=235, Percent_Identity=31.9148936170213, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=339, Percent_Identity=29.7935103244838, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319370, Length=338, Percent_Identity=28.9940828402367, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6319603, Length=315, Percent_Identity=30.7936507936508, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320016, Length=258, Percent_Identity=29.8449612403101, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24638766, Length=340, Percent_Identity=30.8823529411765, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24658560, Length=332, Percent_Identity=31.3253012048193, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28574560, Length=308, Percent_Identity=31.1688311688312, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281361666, Length=374, Percent_Identity=28.0748663101604, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=374, Percent_Identity=28.0748663101604, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=374, Percent_Identity=28.0748663101604, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583988, Length=306, Percent_Identity=27.1241830065359, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583986, Length=306, Percent_Identity=27.1241830065359, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583984, Length=306, Percent_Identity=27.1241830065359, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583992, Length=306, Percent_Identity=27.1241830065359, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20129479, Length=244, Percent_Identity=28.6885245901639, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 49999; Mature: 49999

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPN
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GSHLEAEVVGFEGERLFLMPQSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTR
CCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
HLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAANPLSRAPISEILDVGVRAINS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
MLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAI
CCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHEEEEE
GEPPATKGYPPSVFAKLPALVERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILD
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHC
GHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMARRLKKLYSRYARSRDLINVG
CCEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
AYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPN
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GSHLEAEVVGFEGERLFLMPQSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTR
CCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCC
HLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAANPLSRAPISEILDVGVRAINS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
MLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAI
CCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHEEEEE
GEPPATKGYPPSVFAKLPALVERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILD
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHC
GHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMARRLKKLYSRYARSRDLINVG
CCEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
AYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]