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The map label for this gene is fliD [H]

Identifier: 74317610

GI number: 74317610

Start: 1678403

End: 1680400

Strand: Direct

Name: fliD [H]

Synonym: Tbd_1592

Alternate gene names: 74317610

Gene position: 1678403-1680400 (Clockwise)

Preceding gene: 74317609

Following gene: 74317611

Centisome position: 57.68

GC content: 63.51

Gene sequence:

>1998_bases
ATGGCAACCACAAGTTCGGTTCTTGATATCAGCAGCATCGTCAGTCAGCTGATGGCGGTGGAACGCCGCCCGCTGACCAA
GCTCGCAGCCAGGGAAGCTGGCTACCAAGCCAGACTCTCCGCCTACGGCAGCGTCAAGGGCGCCGTCAGCAGCTTCCAGG
CTGCGCTTCAGGCGCTGAACAGTCCGAGCAAGTTCCAGTCGGTCACGGCGACCGCCTCGGACAGCGCTGTTTTTTCCGCC
TCGGCCACCAGCACCGCGGTGCCGGGCACCTATTCCATCGAGGTGGCCACCCTCGCCCAGCCACAGAAGCTCGTTGCGGC
CGGGCAGGCCAGCAGCAGCGCTGCGATCGGTGGGGGAACGGCGACCACGGTCACCTTCGATTTTGGCACCATCAGTGGCG
GCACGTTGGCCAACGGGGTCTATAGCGGTGCGAGTTTTGTTTCGAACGGCGACGGGACCAAGAGCATTACCATCGACAGC
AGCAACAATTCGCTGCTGGGCATACGCGACGCGATCAACGCCGCGAAAATAGGCGTCGCCGCCACCATCGTCAACGACGG
CAGCGGTTCGCCATACCGCCTCGCGCTGGCGGCGGACCACAACGGCGTCGACCAGAGCCTCAAGATTTCGGTGAGCGGCG
ACGCCGCGATCGACAGTTTGCTCGCACACGACCCGGGCGGCGTGCAGAATCTCACTGAAACAGCGGCCGCGCAGAACGCC
AATCTCAAGATCAACGGCGTCACCGTCACCAAGACCTCGAATACGATCTCCGACGCGGTCGAGGGCGTGACGCTGAACCT
GAACAAGGTGACCAGCTCGCCTGCAAGCCTGACGGTCGCACGCGACACGAACTCGATCAAGGCTTCGATCAACAGCTTCG
TCAAAGCCTACAACGAGCTGTCGGGGACGCTGAAAAACGTTTCGGCCTACGATGCCGCCGCCAAGAAGGGGGCGATCCTG
CAAGGCGACGCCACGGTTCGGTCGCTGCAAACGCAACTGCGGGCGATGATCGGTGCACCGGTCGAGGGTGCGCCCGGCGA
CCTGAAGACCTTGGCCAGTATCGGGATCACCTTCCAGAAGGACGGTACCCTGGGAGTGGACCAGGGCAAGCTCAGCACGG
CGATAGCCGATCACTTCGACGAGATCGCATCACTGTTCACCACGGTCGGCAGCAGCACCGACAGCCTGGTGAGCTTCAGC
AGCGGCACCCGCAGCACCAAGGCAGGCAGCTACGCACTCGACGTCACGCAGGTTGCGACCCAAGGCAAAACCGTCGGCAA
GACGATCTCCGTCCCGCTCGTCATTGCGGCCGGCAGCAACGACACGCTCAACCTCAGTATCGACGGCGTCGGCGCCTCAG
TCGAACTTTCACCCGGCACCTACACGACGGCGGGTGCACTGGCGGCCGAACTGCAAACCAAGATCAATGGCGCAGCCGCC
TTGTCCGGGGCGGGTGTGTCCGTCGCGGTTTCGGAAAGCGCCGGGAAACTCACTATTACGTCCGTAAAGTACGGTTCGGG
TTCGACGGTGCTCATCAGTGGCGGAACCGCCGAGGTGTCGCTGGGTCTAGACGGCGACGCACCTAGCGATGGGGTCGACG
TGGCGGGCACGATTGCCGGCGTGACGGCCAGCGGCTCCGGCCAAGTCTTGACCGCGAGCAGCGGCGAGGCCACGGGCCTG
GCGATCGTGGTGAACGGGGGGACGCTCGGCAGCCGCGGCAGGCTGCACTACTCCCAAGGCTATGCCGCGACGCTCAACAG
CTGGGCAAGCGCGGTCCTGGACAGCGACAGCATCATTTCCGCGCGAACGGACGGCATCGACAGAAGCATCAAGGATGTGG
CCAAGCGGCGCTCCGAATTCGAAGCGCGTCTGGTCAACATGGAAAAGCGCTATCGCGCGCAGTTCGTCGCACTCGACTCC
ATGCTCGCCAGCATGAACAACACCAGCAATTACCTGACCCAGCAACTGGCCAACCTGCCCGGCAACCAGAAATCATAG

Upstream 100 bases:

>100_bases
TTCGGCAATTCCCCACCGAGGAAGCCTTGTCGATCGCCAGAGCGATCGACAGCTTCCAGCAGGGATTGCTGATCAAGCAG
AAGGCCTGAGGAAAGCGACC

Downstream 100 bases:

>100_bases
CGAGGAATCAAGACGTGTACACGAACCCCAGAAGTGCCGCGCGCGCCTACGTCAACGTAGGCTTGGAAACCGGCGTGAGC
GTGGCCAGCCCTCACCAACT

Product: flagellar hook-associated protein 2

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MATTSSVLDISSIVSQLMAVERRPLTKLAAREAGYQARLSAYGSVKGAVSSFQAALQALNSPSKFQSVTATASDSAVFSA
SATSTAVPGTYSIEVATLAQPQKLVAAGQASSSAAIGGGTATTVTFDFGTISGGTLANGVYSGASFVSNGDGTKSITIDS
SNNSLLGIRDAINAAKIGVAATIVNDGSGSPYRLALAADHNGVDQSLKISVSGDAAIDSLLAHDPGGVQNLTETAAAQNA
NLKINGVTVTKTSNTISDAVEGVTLNLNKVTSSPASLTVARDTNSIKASINSFVKAYNELSGTLKNVSAYDAAAKKGAIL
QGDATVRSLQTQLRAMIGAPVEGAPGDLKTLASIGITFQKDGTLGVDQGKLSTAIADHFDEIASLFTTVGSSTDSLVSFS
SGTRSTKAGSYALDVTQVATQGKTVGKTISVPLVIAAGSNDTLNLSIDGVGASVELSPGTYTTAGALAAELQTKINGAAA
LSGAGVSVAVSESAGKLTITSVKYGSGSTVLISGGTAEVSLGLDGDAPSDGVDVAGTIAGVTASGSGQVLTASSGEATGL
AIVVNGGTLGSRGRLHYSQGYAATLNSWASAVLDSDSIISARTDGIDRSIKDVAKRRSEFEARLVNMEKRYRAQFVALDS
MLASMNNTSNYLTQQLANLPGNQKS

Sequences:

>Translated_665_residues
MATTSSVLDISSIVSQLMAVERRPLTKLAAREAGYQARLSAYGSVKGAVSSFQAALQALNSPSKFQSVTATASDSAVFSA
SATSTAVPGTYSIEVATLAQPQKLVAAGQASSSAAIGGGTATTVTFDFGTISGGTLANGVYSGASFVSNGDGTKSITIDS
SNNSLLGIRDAINAAKIGVAATIVNDGSGSPYRLALAADHNGVDQSLKISVSGDAAIDSLLAHDPGGVQNLTETAAAQNA
NLKINGVTVTKTSNTISDAVEGVTLNLNKVTSSPASLTVARDTNSIKASINSFVKAYNELSGTLKNVSAYDAAAKKGAIL
QGDATVRSLQTQLRAMIGAPVEGAPGDLKTLASIGITFQKDGTLGVDQGKLSTAIADHFDEIASLFTTVGSSTDSLVSFS
SGTRSTKAGSYALDVTQVATQGKTVGKTISVPLVIAAGSNDTLNLSIDGVGASVELSPGTYTTAGALAAELQTKINGAAA
LSGAGVSVAVSESAGKLTITSVKYGSGSTVLISGGTAEVSLGLDGDAPSDGVDVAGTIAGVTASGSGQVLTASSGEATGL
AIVVNGGTLGSRGRLHYSQGYAATLNSWASAVLDSDSIISARTDGIDRSIKDVAKRRSEFEARLVNMEKRYRAQFVALDS
MLASMNNTSNYLTQQLANLPGNQKS
>Mature_664_residues
ATTSSVLDISSIVSQLMAVERRPLTKLAAREAGYQARLSAYGSVKGAVSSFQAALQALNSPSKFQSVTATASDSAVFSAS
ATSTAVPGTYSIEVATLAQPQKLVAAGQASSSAAIGGGTATTVTFDFGTISGGTLANGVYSGASFVSNGDGTKSITIDSS
NNSLLGIRDAINAAKIGVAATIVNDGSGSPYRLALAADHNGVDQSLKISVSGDAAIDSLLAHDPGGVQNLTETAAAQNAN
LKINGVTVTKTSNTISDAVEGVTLNLNKVTSSPASLTVARDTNSIKASINSFVKAYNELSGTLKNVSAYDAAAKKGAILQ
GDATVRSLQTQLRAMIGAPVEGAPGDLKTLASIGITFQKDGTLGVDQGKLSTAIADHFDEIASLFTTVGSSTDSLVSFSS
GTRSTKAGSYALDVTQVATQGKTVGKTISVPLVIAAGSNDTLNLSIDGVGASVELSPGTYTTAGALAAELQTKINGAAAL
SGAGVSVAVSESAGKLTITSVKYGSGSTVLISGGTAEVSLGLDGDAPSDGVDVAGTIAGVTASGSGQVLTASSGEATGLA
IVVNGGTLGSRGRLHYSQGYAATLNSWASAVLDSDSIISARTDGIDRSIKDVAKRRSEFEARLVNMEKRYRAQFVALDSM
LASMNNTSNYLTQQLANLPGNQKS

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=425, Percent_Identity=37.1764705882353, Blast_Score=198, Evalue=8e-52,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 66749; Mature: 66618

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTSSVLDISSIVSQLMAVERRPLTKLAAREAGYQARLSAYGSVKGAVSSFQAALQALN
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHC
SPSKFQSVTATASDSAVFSASATSTAVPGTYSIEVATLAQPQKLVAAGQASSSAAIGGGT
CCHHHHEEEEECCCCEEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCCCCCCCE
ATTVTFDFGTISGGTLANGVYSGASFVSNGDGTKSITIDSSNNSLLGIRDAINAAKIGVA
EEEEEEECCCCCCCCHHCCHHCCCHHCCCCCCCEEEEEECCCCCEEEEHHHCCHHHCEEE
ATIVNDGSGSPYRLALAADHNGVDQSLKISVSGDAAIDSLLAHDPGGVQNLTETAAAQNA
EEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCC
NLKINGVTVTKTSNTISDAVEGVTLNLNKVTSSPASLTVARDTNSIKASINSFVKAYNEL
CEEEEEEEEEECCCHHHHHHCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SGTLKNVSAYDAAAKKGAILQGDATVRSLQTQLRAMIGAPVEGAPGDLKTLASIGITFQK
HHHHHCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEC
DGTLGVDQGKLSTAIADHFDEIASLFTTVGSSTDSLVSFSSGTRSTKAGSYALDVTQVAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEHHHHHH
QGKTVGKTISVPLVIAAGSNDTLNLSIDGVGASVELSPGTYTTAGALAAELQTKINGAAA
CCCCCCCEEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCEE
LSGAGVSVAVSESAGKLTITSVKYGSGSTVLISGGTAEVSLGLDGDAPSDGVDVAGTIAG
ECCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEEE
VTASGSGQVLTASSGEATGLAIVVNGGTLGSRGRLHYSQGYAATLNSWASAVLDSDSIIS
EEECCCCCEEEECCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEE
ARTDGIDRSIKDVAKRRSEFEARLVNMEKRYRAQFVALDSMLASMNNTSNYLTQQLANLP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNQKS
CCCCC
>Mature Secondary Structure 
ATTSSVLDISSIVSQLMAVERRPLTKLAAREAGYQARLSAYGSVKGAVSSFQAALQALN
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHC
SPSKFQSVTATASDSAVFSASATSTAVPGTYSIEVATLAQPQKLVAAGQASSSAAIGGGT
CCHHHHEEEEECCCCEEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCCCCCCCE
ATTVTFDFGTISGGTLANGVYSGASFVSNGDGTKSITIDSSNNSLLGIRDAINAAKIGVA
EEEEEEECCCCCCCCHHCCHHCCCHHCCCCCCCEEEEEECCCCCEEEEHHHCCHHHCEEE
ATIVNDGSGSPYRLALAADHNGVDQSLKISVSGDAAIDSLLAHDPGGVQNLTETAAAQNA
EEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCC
NLKINGVTVTKTSNTISDAVEGVTLNLNKVTSSPASLTVARDTNSIKASINSFVKAYNEL
CEEEEEEEEEECCCHHHHHHCCEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SGTLKNVSAYDAAAKKGAILQGDATVRSLQTQLRAMIGAPVEGAPGDLKTLASIGITFQK
HHHHHCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEC
DGTLGVDQGKLSTAIADHFDEIASLFTTVGSSTDSLVSFSSGTRSTKAGSYALDVTQVAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEHHHHHH
QGKTVGKTISVPLVIAAGSNDTLNLSIDGVGASVELSPGTYTTAGALAAELQTKINGAAA
CCCCCCCEEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCEE
LSGAGVSVAVSESAGKLTITSVKYGSGSTVLISGGTAEVSLGLDGDAPSDGVDVAGTIAG
ECCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEEE
VTASGSGQVLTASSGEATGLAIVVNGGTLGSRGRLHYSQGYAATLNSWASAVLDSDSIIS
EEECCCCCEEEECCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEE
ARTDGIDRSIKDVAKRRSEFEARLVNMEKRYRAQFVALDSMLASMNNTSNYLTQQLANLP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNQKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]