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The map label for this gene is pfp [H]

Identifier: 74317520

GI number: 74317520

Start: 1592154

End: 1593410

Strand: Reverse

Name: pfp [H]

Synonym: Tbd_1502

Alternate gene names: 74317520

Gene position: 1593410-1592154 (Counterclockwise)

Preceding gene: 74317521

Following gene: 74317519

Centisome position: 54.76

GC content: 62.45

Gene sequence:

>1257_bases
ATGGCGAAAAAAATGAACGCCTTCTACGCGCAGTCCGGCGGCGTCACCGCCGTCATCAACGCGTCGGCCTGCGGCGTGAT
CGAGACCGCGCGCAAGAACAAGGACAAGATTGGCAAGGTCTACGCCGGCCGCAACGGCATCATCGGCGCGCTGACCGAAG
ACCTCATCGACACCAGCAAGGAATCCGACGCCGCGATCGCGGCGCTGCGCTCGACGCCGTCGGGCGCCTTCGGCTCGTGC
CGCTTCAAGCTCAAGTCGCTCGAAGCCAACAAGCGCGAATACGAACGCCTGATCGAGGTGTTCAAGGCGCACAACATCGG
CTACTTCTTCTATAACGGCGGCGGCGATTCGGCGGATACCTGCTTCAAGGTCAGCCAGCTGTCCGAAGCGATGGGCTATC
CGATCCAGGCGATCCACGTGCCGAAGACCGTCGACAACGACCTGCCGATCACCGACTGCTGCCCGGGCTTCGGCTCGGTC
GCCAAATACATCGCCGTGTCGACGCTCGAAGCGAGCTACGACGTGCGCTCGATGGCCAAGACCTCGACCAAGGTCTTCGT
GATCGAGGTCATGGGCCGCCACGCCGGCTGGATCGCGGCAGCGGGCGGTCTCGTCGAGGACCACGGCATTCCGGTCGTGA
TCCTGTTCCCCGAAATCGAATTCGATCAGAAGAAATTCCTCGCGCTCGTCGACAAGAAGGTCAAGGAATTCGGCTTCTGC
ACCGTCGTCGTGTCCGAAGGCTGCCACTACCCGGATGGCAAGTTCCTCGCCGAACAGGGCACGCGCGACGCCTTCGGCCA
CGCCCAGCTCGGCGGCGCGGCGCCGGTCGTCGCCAACATGATCAAGGATGCGCTCGGCCACAAGTTCCACTGGGCCGTCG
CCGATTACCTGCAGCGCGCCGCGCGCCACATCGCCTCGAAAACGGACGTCAAGCAGGCCTATGAGCTCGGCAAGAAAGCC
GTCGAACTCGCGATCCGCGGCCACAACTCGGTCATGCCGACCGTCGACCGGCTCTCCGACAAGCCCTACAAATACAAGAT
CGGCGTAGCCGATCTCAAGGATGTCGCCAACGTCGAGAAATTCATGCCGCGCGACTTCATCACCAAGGACGGCTTCGGCA
TCACCGACAAGTGCAAGCGTTACCTCACGCCGCTCATCCAGGGCGAGGACTATCCGAAGTACAAGGACGGCTTGCCGGTC
TACGTGACGCTCAAGAACGTCGCGGTGGCCAAGAAGCTGGCGGAATTCAAGCTCTAG

Upstream 100 bases:

>100_bases
CGAGACCGCCGGAAACAGTTGACAGAGCAAAGCCAGCCGGGAAACCCGCTGGCTTTTTGTTTGCGAACGAATACGGAAAC
AATCAGGAGATAGCACCACC

Downstream 100 bases:

>100_bases
AAGCTTCGAGGGGAGCAGGGAGACATCAGAAGATGACGCTCGACCGCGCGCGGCAACTGCTCAAGGTCCAGGCGGACTTT
GGCGGCTTTTACAACGGCAA

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MAKKMNAFYAQSGGVTAVINASACGVIETARKNKDKIGKVYAGRNGIIGALTEDLIDTSKESDAAIAALRSTPSGAFGSC
RFKLKSLEANKREYERLIEVFKAHNIGYFFYNGGGDSADTCFKVSQLSEAMGYPIQAIHVPKTVDNDLPITDCCPGFGSV
AKYIAVSTLEASYDVRSMAKTSTKVFVIEVMGRHAGWIAAAGGLVEDHGIPVVILFPEIEFDQKKFLALVDKKVKEFGFC
TVVVSEGCHYPDGKFLAEQGTRDAFGHAQLGGAAPVVANMIKDALGHKFHWAVADYLQRAARHIASKTDVKQAYELGKKA
VELAIRGHNSVMPTVDRLSDKPYKYKIGVADLKDVANVEKFMPRDFITKDGFGITDKCKRYLTPLIQGEDYPKYKDGLPV
YVTLKNVAVAKKLAEFKL

Sequences:

>Translated_418_residues
MAKKMNAFYAQSGGVTAVINASACGVIETARKNKDKIGKVYAGRNGIIGALTEDLIDTSKESDAAIAALRSTPSGAFGSC
RFKLKSLEANKREYERLIEVFKAHNIGYFFYNGGGDSADTCFKVSQLSEAMGYPIQAIHVPKTVDNDLPITDCCPGFGSV
AKYIAVSTLEASYDVRSMAKTSTKVFVIEVMGRHAGWIAAAGGLVEDHGIPVVILFPEIEFDQKKFLALVDKKVKEFGFC
TVVVSEGCHYPDGKFLAEQGTRDAFGHAQLGGAAPVVANMIKDALGHKFHWAVADYLQRAARHIASKTDVKQAYELGKKA
VELAIRGHNSVMPTVDRLSDKPYKYKIGVADLKDVANVEKFMPRDFITKDGFGITDKCKRYLTPLIQGEDYPKYKDGLPV
YVTLKNVAVAKKLAEFKL
>Mature_417_residues
AKKMNAFYAQSGGVTAVINASACGVIETARKNKDKIGKVYAGRNGIIGALTEDLIDTSKESDAAIAALRSTPSGAFGSCR
FKLKSLEANKREYERLIEVFKAHNIGYFFYNGGGDSADTCFKVSQLSEAMGYPIQAIHVPKTVDNDLPITDCCPGFGSVA
KYIAVSTLEASYDVRSMAKTSTKVFVIEVMGRHAGWIAAAGGLVEDHGIPVVILFPEIEFDQKKFLALVDKKVKEFGFCT
VVVSEGCHYPDGKFLAEQGTRDAFGHAQLGGAAPVVANMIKDALGHKFHWAVADYLQRAARHIASKTDVKQAYELGKKAV
ELAIRGHNSVMPTVDRLSDKPYKYKIGVADLKDVANVEKFMPRDFITKDGFGITDKCKRYLTPLIQGEDYPKYKDGLPVY
VTLKNVAVAKKLAEFKL

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

None

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 45607; Mature: 45476

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKMNAFYAQSGGVTAVINASACGVIETARKNKDKIGKVYAGRNGIIGALTEDLIDTSK
CCCCCCHHEECCCCEEEEEECCCCCHHHHHHCCHHHHCEEECCCCCCHHHHHHHHHHCCC
ESDAAIAALRSTPSGAFGSCRFKLKSLEANKREYERLIEVFKAHNIGYFFYNGGGDSADT
CCCHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
CFKVSQLSEAMGYPIQAIHVPKTVDNDLPITDCCPGFGSVAKYIAVSTLEASYDVRSMAK
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSTKVFVIEVMGRHAGWIAAAGGLVEDHGIPVVILFPEIEFDQKKFLALVDKKVKEFGFC
CCCEEEEEEEECCCCCCEEECCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEE
TVVVSEGCHYPDGKFLAEQGTRDAFGHAQLGGAAPVVANMIKDALGHKFHWAVADYLQRA
EEEEECCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARHIASKTDVKQAYELGKKAVELAIRGHNSVMPTVDRLSDKPYKYKIGVADLKDVANVEK
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHH
FMPRDFITKDGFGITDKCKRYLTPLIQGEDYPKYKDGLPVYVTLKNVAVAKKLAEFKL
HCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKMNAFYAQSGGVTAVINASACGVIETARKNKDKIGKVYAGRNGIIGALTEDLIDTSK
CCCCCHHEECCCCEEEEEECCCCCHHHHHHCCHHHHCEEECCCCCCHHHHHHHHHHCCC
ESDAAIAALRSTPSGAFGSCRFKLKSLEANKREYERLIEVFKAHNIGYFFYNGGGDSADT
CCCHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
CFKVSQLSEAMGYPIQAIHVPKTVDNDLPITDCCPGFGSVAKYIAVSTLEASYDVRSMAK
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSTKVFVIEVMGRHAGWIAAAGGLVEDHGIPVVILFPEIEFDQKKFLALVDKKVKEFGFC
CCCEEEEEEEECCCCCCEEECCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEE
TVVVSEGCHYPDGKFLAEQGTRDAFGHAQLGGAAPVVANMIKDALGHKFHWAVADYLQRA
EEEEECCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARHIASKTDVKQAYELGKKAVELAIRGHNSVMPTVDRLSDKPYKYKIGVADLKDVANVEK
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCCCEEEEECHHHHHHHHHHHH
FMPRDFITKDGFGITDKCKRYLTPLIQGEDYPKYKDGLPVYVTLKNVAVAKKLAEFKL
HCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]