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The map label for this gene is pilQ [H]

Identifier: 74317457

GI number: 74317457

Start: 1526329

End: 1528299

Strand: Direct

Name: pilQ [H]

Synonym: Tbd_1439

Alternate gene names: 74317457

Gene position: 1526329-1528299 (Clockwise)

Preceding gene: 74317456

Following gene: 74317458

Centisome position: 52.45

GC content: 67.78

Gene sequence:

>1971_bases
TTGTCCTTCCATCCGTCGCCCTTGCTCACCGCGCTGGTCGCGTTCAGCCTGACCGCGTGCGCAGGCACCGGTCTCAAGGA
GGGCCGCAAGCTGATCGACGCCGGGCAGCCCGAGGCCGGGATCGCGCGCCTGCGCACCGCCCTGGCCGAAGAACCCGACA
ACATCAAGCTCAAGGCCTACTACCATACGCAGCGCGAGCGCATCGCCAGCGAACTATTGGTGCGGGCGCAACAGGATGTC
CACGCCGCACGCTTCGACGCGGCCGAAACCAAGCTCGACAGCGTGCTCGAAATGCATCCGGAAAATCCGCGCGCGCTCGC
CCTGCGCGCCAATCTCGAGACGGCGCGCCGCCACGAAGCGGCCTTGCAGCAGGCGAACAAGGCGCTCGCCGCGGGTAAGG
TCGACGCGGCCGCGCAGGCTGCGCGCGAGATCCTCGCGCAGGCGCCGGGGCATGCCGGCGCGCTTGCCCTGCTGCGGCAG
ACCCAGGCCGCGCACGCGCCCGACGAACTCGCGATGCGCCGGCTCGGCCCGGCCTTTCACAAACCGATCACGCTGGAATT
TCGCGACGCGCCGCTGCGCAACGTCTTCGACATGATCGCCCGCCAGTCCGGCCTCAACTTCGTTTTCGACAAGGATGTCC
GTCTCGACACCAAGGCCACGCTGTTCGCGCGCAACACGCCGATCGACGAGGCCGTCGACATGCTCCTGATGACCGGGCAG
CTGTCGAAAAAGGTGGTCAACGCCAACACGCTGTTGATTTATCCCGACCAGCCGCAGAAGCAGAAGGCCTACCAGGAGCT
GATGGTGAAAAGCTTCTACCTCGGCAACGCCGACGCCAAGGCGACGATGGCAATGCTGCGCACGCTGGTCAAGGCGAAGG
ACCTGCACGTCGACGAACGGCTCAACCTGCTGGTCATGCGCGACACGCCCGATGCGATCCGTCTCGCCGAGCGCATCGTC
GCCGTGCAGGACCTGGCCGAGCCCGAGGTCATGCTCGAGGTCGAGGTGCTCGAAGTGAAGCGCGGGCGCCTGCTCGACCT
CGGCATCCAGTACCCGACCAATTTCAGCCTGCTCAACCTGCCGCCGGCGACGAGTTCGACCATCGGCCCCGGCGGGGTCG
TCACCAATACGACCCCGCCGCCATCGGTGCTGACCGTCGAGAGCCTGAAGAACATCACGGCGAGCCAGATCGCGATCAGC
CCGACGCCCGGCGTCGACCTCAGAAAGCAGGACAGCGACGTCAACATCCTCGCCAATCCGCGCATCCGCGTGAAGAACCG
CGAAAAGGCCAAGATCCACATCGGCGACAAGGTGCCGGTGATCACGTCCAACACGACGTCGACCGGCGTCGTCTCCGAAT
CGGTGTCGTATCTCGACGTCGGCCTCAAGCTCGACGTCGAACCGAGCGTGCTGATGCGCGAGGACGTGCAGATCCGCGTC
GGCCTCGAGGTTTCCAACATCGTGCGCGAGATCCGCAGCGGCAACGGCACGCTGACCTACCAGATCGGGACGCGCAACGC
CGGCACGACGCTGCGCCTGAAGGACGGCGAGACCCAGGTGCTCGCCGGCCTGATCTCGGACGAGGACCGCAGCACGGCGA
GCCGCATTCCCGGGCTCGGCGATCTGCCGCTGATCGGCCGCCTGTTTTCGAGCCAGCGCGACGAGCGCAACAAGACCGAA
ATCGTGCTTCTGATCACGCCGCGGGTGCTGCGCAGCGACGCGACGCGGCTGCCCGCACTGACCGAATTCCGGGGCGGCAC
CGAGAACGCGATCGGCGGCGGCGGCGCCGTGCCGTTCAGCGCGCCGGCCCTGCCCGAAGCGTCGCAGCCGCCGCTGCCCG
ACGAAGGCCCGACCTCGCCGTCGGCGATTGCACCCGCGCCCGAGTCGGAGATCCCGCCGGCGCCCGACACGTTCGGGACG
CCGAGCGTGCCTGTCCCACAGATTCCCGCACCGCCGGACGCGGCCGATTGA

Upstream 100 bases:

>100_bases
TTGGACGGCGTCTGGCGCCTCGAACCGACCACGGGTCGCACGCTCAGTTTCACCTACCTGCCGCTGAACCAGACGCGCAG
TCTGCAAACAGGAGAATAAG

Downstream 100 bases:

>100_bases
CGATGGCCCGCGCGCCCGCAGGCTTCAGCCTGATCGAACTCATGGTCACGCTGGCCGTGCTGGCGCTCCTGGCGAGCGTC
GCGCTGCCCTATGGCCAGCT

Product: type II secretion system protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MSFHPSPLLTALVAFSLTACAGTGLKEGRKLIDAGQPEAGIARLRTALAEEPDNIKLKAYYHTQRERIASELLVRAQQDV
HAARFDAAETKLDSVLEMHPENPRALALRANLETARRHEAALQQANKALAAGKVDAAAQAAREILAQAPGHAGALALLRQ
TQAAHAPDELAMRRLGPAFHKPITLEFRDAPLRNVFDMIARQSGLNFVFDKDVRLDTKATLFARNTPIDEAVDMLLMTGQ
LSKKVVNANTLLIYPDQPQKQKAYQELMVKSFYLGNADAKATMAMLRTLVKAKDLHVDERLNLLVMRDTPDAIRLAERIV
AVQDLAEPEVMLEVEVLEVKRGRLLDLGIQYPTNFSLLNLPPATSSTIGPGGVVTNTTPPPSVLTVESLKNITASQIAIS
PTPGVDLRKQDSDVNILANPRIRVKNREKAKIHIGDKVPVITSNTTSTGVVSESVSYLDVGLKLDVEPSVLMREDVQIRV
GLEVSNIVREIRSGNGTLTYQIGTRNAGTTLRLKDGETQVLAGLISDEDRSTASRIPGLGDLPLIGRLFSSQRDERNKTE
IVLLITPRVLRSDATRLPALTEFRGGTENAIGGGGAVPFSAPALPEASQPPLPDEGPTSPSAIAPAPESEIPPAPDTFGT
PSVPVPQIPAPPDAAD

Sequences:

>Translated_656_residues
MSFHPSPLLTALVAFSLTACAGTGLKEGRKLIDAGQPEAGIARLRTALAEEPDNIKLKAYYHTQRERIASELLVRAQQDV
HAARFDAAETKLDSVLEMHPENPRALALRANLETARRHEAALQQANKALAAGKVDAAAQAAREILAQAPGHAGALALLRQ
TQAAHAPDELAMRRLGPAFHKPITLEFRDAPLRNVFDMIARQSGLNFVFDKDVRLDTKATLFARNTPIDEAVDMLLMTGQ
LSKKVVNANTLLIYPDQPQKQKAYQELMVKSFYLGNADAKATMAMLRTLVKAKDLHVDERLNLLVMRDTPDAIRLAERIV
AVQDLAEPEVMLEVEVLEVKRGRLLDLGIQYPTNFSLLNLPPATSSTIGPGGVVTNTTPPPSVLTVESLKNITASQIAIS
PTPGVDLRKQDSDVNILANPRIRVKNREKAKIHIGDKVPVITSNTTSTGVVSESVSYLDVGLKLDVEPSVLMREDVQIRV
GLEVSNIVREIRSGNGTLTYQIGTRNAGTTLRLKDGETQVLAGLISDEDRSTASRIPGLGDLPLIGRLFSSQRDERNKTE
IVLLITPRVLRSDATRLPALTEFRGGTENAIGGGGAVPFSAPALPEASQPPLPDEGPTSPSAIAPAPESEIPPAPDTFGT
PSVPVPQIPAPPDAAD
>Mature_655_residues
SFHPSPLLTALVAFSLTACAGTGLKEGRKLIDAGQPEAGIARLRTALAEEPDNIKLKAYYHTQRERIASELLVRAQQDVH
AARFDAAETKLDSVLEMHPENPRALALRANLETARRHEAALQQANKALAAGKVDAAAQAAREILAQAPGHAGALALLRQT
QAAHAPDELAMRRLGPAFHKPITLEFRDAPLRNVFDMIARQSGLNFVFDKDVRLDTKATLFARNTPIDEAVDMLLMTGQL
SKKVVNANTLLIYPDQPQKQKAYQELMVKSFYLGNADAKATMAMLRTLVKAKDLHVDERLNLLVMRDTPDAIRLAERIVA
VQDLAEPEVMLEVEVLEVKRGRLLDLGIQYPTNFSLLNLPPATSSTIGPGGVVTNTTPPPSVLTVESLKNITASQIAISP
TPGVDLRKQDSDVNILANPRIRVKNREKAKIHIGDKVPVITSNTTSTGVVSESVSYLDVGLKLDVEPSVLMREDVQIRVG
LEVSNIVREIRSGNGTLTYQIGTRNAGTTLRLKDGETQVLAGLISDEDRSTASRIPGLGDLPLIGRLFSSQRDERNKTEI
VLLITPRVLRSDATRLPALTEFRGGTENAIGGGGAVPFSAPALPEASQPPLPDEGPTSPSAIAPAPESEIPPAPDTFGTP
SVPVPQIPAPPDAAD

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=411, Percent_Identity=25.7907542579075, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI87082242, Length=350, Percent_Identity=28, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 70676; Mature: 70545

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFHPSPLLTALVAFSLTACAGTGLKEGRKLIDAGQPEAGIARLRTALAEEPDNIKLKAY
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEE
YHTQRERIASELLVRAQQDVHAARFDAAETKLDSVLEMHPENPRALALRANLETARRHEA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
ALQQANKALAAGKVDAAAQAAREILAQAPGHAGALALLRQTQAAHAPDELAMRRLGPAFH
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCHHHC
KPITLEFRDAPLRNVFDMIARQSGLNFVFDKDVRLDTKATLFARNTPIDEAVDMLLMTGQ
CCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCEECCCEEEEECCCCHHHHHHHHHHHHH
LSKKVVNANTLLIYPDQPQKQKAYQELMVKSFYLGNADAKATMAMLRTLVKAKDLHVDER
HHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
LNLLVMRDTPDAIRLAERIVAVQDLAEPEVMLEVEVLEVKRGRLLDLGIQYPTNFSLLNL
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCEEEEC
PPATSSTIGPGGVVTNTTPPPSVLTVESLKNITASQIAISPTPGVDLRKQDSDVNILANP
CCCCCCCCCCCCEECCCCCCCCEEEHHHHHCCCHHEEEECCCCCCCCEECCCCEEEEECC
RIRVKNREKAKIHIGDKVPVITSNTTSTGVVSESVSYLDVGLKLDVEPSVLMREDVQIRV
EEEECCCCCEEEEECCCCEEEECCCCCCCHHHHCCCEEEECEEECCCCCEEEECCCEEEE
GLEVSNIVREIRSGNGTLTYQIGTRNAGTTLRLKDGETQVLAGLISDEDRSTASRIPGLG
CCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEHHHHHCCCCCHHHHHCCCCC
DLPLIGRLFSSQRDERNKTEIVLLITPRVLRSDATRLPALTEFRGGTENAIGGGGAVPFS
CCHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
APALPEASQPPLPDEGPTSPSAIAPAPESEIPPAPDTFGTPSVPVPQIPAPPDAAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFHPSPLLTALVAFSLTACAGTGLKEGRKLIDAGQPEAGIARLRTALAEEPDNIKLKAY
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEE
YHTQRERIASELLVRAQQDVHAARFDAAETKLDSVLEMHPENPRALALRANLETARRHEA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
ALQQANKALAAGKVDAAAQAAREILAQAPGHAGALALLRQTQAAHAPDELAMRRLGPAFH
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCHHHC
KPITLEFRDAPLRNVFDMIARQSGLNFVFDKDVRLDTKATLFARNTPIDEAVDMLLMTGQ
CCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCEECCCEEEEECCCCHHHHHHHHHHHHH
LSKKVVNANTLLIYPDQPQKQKAYQELMVKSFYLGNADAKATMAMLRTLVKAKDLHVDER
HHHHEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
LNLLVMRDTPDAIRLAERIVAVQDLAEPEVMLEVEVLEVKRGRLLDLGIQYPTNFSLLNL
CCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCEEEEC
PPATSSTIGPGGVVTNTTPPPSVLTVESLKNITASQIAISPTPGVDLRKQDSDVNILANP
CCCCCCCCCCCCEECCCCCCCCEEEHHHHHCCCHHEEEECCCCCCCCEECCCCEEEEECC
RIRVKNREKAKIHIGDKVPVITSNTTSTGVVSESVSYLDVGLKLDVEPSVLMREDVQIRV
EEEECCCCCEEEEECCCCEEEECCCCCCCHHHHCCCEEEECEEECCCCCEEEECCCEEEE
GLEVSNIVREIRSGNGTLTYQIGTRNAGTTLRLKDGETQVLAGLISDEDRSTASRIPGLG
CCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEHHHHHCCCCCHHHHHCCCCC
DLPLIGRLFSSQRDERNKTEIVLLITPRVLRSDATRLPALTEFRGGTENAIGGGGAVPFS
CCHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCC
APALPEASQPPLPDEGPTSPSAIAPAPESEIPPAPDTFGTPSVPVPQIPAPPDAAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]