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The map label for this gene is arpC [H]

Identifier: 74317374

GI number: 74317374

Start: 1436467

End: 1437972

Strand: Reverse

Name: arpC [H]

Synonym: Tbd_1356

Alternate gene names: 74317374

Gene position: 1437972-1436467 (Counterclockwise)

Preceding gene: 74317375

Following gene: 74317373

Centisome position: 49.42

GC content: 71.12

Gene sequence:

>1506_bases
ATGGCGAGCGCTGAAGCCAAGCCGACCGCCGATGCAGGGGGTTCGGGCGCGAGGCGTACTTGCACTCGCGCCGTCGTGGC
CTCGGCGGTACTGGCCAGCCTGCTCGCCGGCTGTGCCGTCGGGCCCGACTTCAAACGGCCGGCCGCGCCCACGGTCGGCA
CCTACACGGCGCAGCCTCTGCCGGCCGAAACCGCGTCGGCGCCCGTCGCGCTGGGACAGGCGCAGCGCTTCGCCGACGCA
CCGGTCGACGCGGCGTGGTGGCAGCGTCTCGGCCCGCCGAAGCTGTCCGCCTTGATCGACGCCGCCTTCGAGGCCAGCCC
CACGCTCGCTTCCGCGCAATCGACCTTGCGGCAGGCGCAGGAACTGCATGCCGCGCGCGCGGGCTCGACGCTTTATCCGC
AGGTCGACGCCGGACTCGGGGCGCAGCGGCAGCGGCTGAGTCCGAGCGCCCTGGGACAGGCCGGCGAGCCGCGGGAATTC
AGCCTGTACAACGCGAGCGTCGGCGTGCGTTACGAACTCGACCTGGCGGGCGGAAACCGGCGCGCCCTCGAAGCCTTGCG
CGCGCGCGTCGAGCACCGGCGCTTCGAGCTCGAAGGCGCTCGCCTAACGCTGGCGGCCAACATCGTGACCACGGCCATCA
CCCAAGCCATGCTCGCCGCGCAGATCGACGCCAGTGAAGCGATCCTGCGTGCGCAGGACGAGCAATTGGCGCTCGCACGG
GAACGCGAGCGCCTCGGCCAGGCGTCGCCCGACGAGGTCCTCACGTTGCAAACACAGGTCGAGCAGACGCGCGCGAGCCT
GCCGCCGCTGCGCCAGCGTCTGGACGAGACTGCACATCTGCTCGCCGTGCTCGCCGGGCGCGCGCCGGGAGCAGGGGACA
TGCCGAGCTTCAGCCTCGAGGAATTCACGCTTCCCGCTGAGTTGCCTCTGGTCGTGCCGTCCGAGCTGGCGCGCCGCCGC
CCCGACATCCGCGCAGCCGAAGCGCTCATGCACGCCGCGAACGCGGAATACGGCGTCGCGGTCGCGAGGCTCTATCCGCA
ACTCAAGCTCTCCGCGAACCTCGGCTCCCAGGCCTTGAGCACCGGCGCCCTGTTCGGCAGCGGTTCGGCCGTGTGGAGCC
TGGTCGGGCAATTGACCCAGCCGCTTTTCAATCCCGGTCTGCCTGCCGAAAAGCGCGCGTCGCTGGCCGCTTTCGAAGCC
GCGTCGGCAAACTACCAGGGCGTCGTGCTCGAAGCGCTGCGCGACGTGGCCGACGTCCTGCGCGCACTGGACCACGACGC
GAGCGCGCTTGCCGCGCTGGCAAGCGCCGACGAAGCCGCGCAGGGCGCACTCGAATCGATGCGTCGCCGCTACGCGCTCG
GCGCGGCGAGCTACCTCGACATTCTCACCGCCGAGCAGCAGGCCCAGCAGACCCGGGTCAATCTCGTCGCCGCCCAGGCG
CAACGCCTCGTCGATAACGCGGCCTTGTACCAGGCATTGGGGGGCGGCTGGACGGAGACGAACTGA

Upstream 100 bases:

>100_bases
CGCGGCGACGGGCGGGCGGTGATCGCCGCGTTCGCGACGCTGCAAAACACCTGCCTGGCCTGTCACGAGAGCTTCCGCAA
GCCTTTCGTGGAGCATTTCT

Downstream 100 bases:

>100_bases
GCACCCGCGCCGCGTCGAATGCGGGTTCCCGCCAGGGGTCGGACGCGCGGCCCGCGCCAGCCTGTCGACCGCGGGTCGAG
GTCTTGCCGAATCCGGCGCG

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MASAEAKPTADAGGSGARRTCTRAVVASAVLASLLAGCAVGPDFKRPAAPTVGTYTAQPLPAETASAPVALGQAQRFADA
PVDAAWWQRLGPPKLSALIDAAFEASPTLASAQSTLRQAQELHAARAGSTLYPQVDAGLGAQRQRLSPSALGQAGEPREF
SLYNASVGVRYELDLAGGNRRALEALRARVEHRRFELEGARLTLAANIVTTAITQAMLAAQIDASEAILRAQDEQLALAR
ERERLGQASPDEVLTLQTQVEQTRASLPPLRQRLDETAHLLAVLAGRAPGAGDMPSFSLEEFTLPAELPLVVPSELARRR
PDIRAAEALMHAANAEYGVAVARLYPQLKLSANLGSQALSTGALFGSGSAVWSLVGQLTQPLFNPGLPAEKRASLAAFEA
ASANYQGVVLEALRDVADVLRALDHDASALAALASADEAAQGALESMRRRYALGAASYLDILTAEQQAQQTRVNLVAAQA
QRLVDNAALYQALGGGWTETN

Sequences:

>Translated_501_residues
MASAEAKPTADAGGSGARRTCTRAVVASAVLASLLAGCAVGPDFKRPAAPTVGTYTAQPLPAETASAPVALGQAQRFADA
PVDAAWWQRLGPPKLSALIDAAFEASPTLASAQSTLRQAQELHAARAGSTLYPQVDAGLGAQRQRLSPSALGQAGEPREF
SLYNASVGVRYELDLAGGNRRALEALRARVEHRRFELEGARLTLAANIVTTAITQAMLAAQIDASEAILRAQDEQLALAR
ERERLGQASPDEVLTLQTQVEQTRASLPPLRQRLDETAHLLAVLAGRAPGAGDMPSFSLEEFTLPAELPLVVPSELARRR
PDIRAAEALMHAANAEYGVAVARLYPQLKLSANLGSQALSTGALFGSGSAVWSLVGQLTQPLFNPGLPAEKRASLAAFEA
ASANYQGVVLEALRDVADVLRALDHDASALAALASADEAAQGALESMRRRYALGAASYLDILTAEQQAQQTRVNLVAAQA
QRLVDNAALYQALGGGWTETN
>Mature_500_residues
ASAEAKPTADAGGSGARRTCTRAVVASAVLASLLAGCAVGPDFKRPAAPTVGTYTAQPLPAETASAPVALGQAQRFADAP
VDAAWWQRLGPPKLSALIDAAFEASPTLASAQSTLRQAQELHAARAGSTLYPQVDAGLGAQRQRLSPSALGQAGEPREFS
LYNASVGVRYELDLAGGNRRALEALRARVEHRRFELEGARLTLAANIVTTAITQAMLAAQIDASEAILRAQDEQLALARE
RERLGQASPDEVLTLQTQVEQTRASLPPLRQRLDETAHLLAVLAGRAPGAGDMPSFSLEEFTLPAELPLVVPSELARRRP
DIRAAEALMHAANAEYGVAVARLYPQLKLSANLGSQALSTGALFGSGSAVWSLVGQLTQPLFNPGLPAEKRASLAAFEAA
SANYQGVVLEALRDVADVLRALDHDASALAALASADEAAQGALESMRRRYALGAASYLDILTAEQQAQQTRVNLVAAQAQ
RLVDNAALYQALGGGWTETN

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=485, Percent_Identity=28.2474226804124, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI2367348, Length=443, Percent_Identity=26.86230248307, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52537; Mature: 52406

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAEAKPTADAGGSGARRTCTRAVVASAVLASLLAGCAVGPDFKRPAAPTVGTYTAQPL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PAETASAPVALGQAQRFADAPVDAAWWQRLGPPKLSALIDAAFEASPTLASAQSTLRQAQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ELHAARAGSTLYPQVDAGLGAQRQRLSPSALGQAGEPREFSLYNASVGVRYELDLAGGNR
HHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCEEEEEECCEEEEEEEEECCCCH
RALEALRARVEHRRFELEGARLTLAANIVTTAITQAMLAAQIDASEAILRAQDEQLALAR
HHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
ERERLGQASPDEVLTLQTQVEQTRASLPPLRQRLDETAHLLAVLAGRAPGAGDMPSFSLE
HHHHCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EFTLPAELPLVVPSELARRRPDIRAAEALMHAANAEYGVAVARLYPQLKLSANLGSQALS
HCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHHHH
TGALFGSGSAVWSLVGQLTQPLFNPGLPAEKRASLAAFEAASANYQGVVLEALRDVADVL
HCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RALDHDASALAALASADEAAQGALESMRRRYALGAASYLDILTAEQQAQQTRVNLVAAQA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLVDNAALYQALGGGWTETN
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASAEAKPTADAGGSGARRTCTRAVVASAVLASLLAGCAVGPDFKRPAAPTVGTYTAQPL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PAETASAPVALGQAQRFADAPVDAAWWQRLGPPKLSALIDAAFEASPTLASAQSTLRQAQ
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ELHAARAGSTLYPQVDAGLGAQRQRLSPSALGQAGEPREFSLYNASVGVRYELDLAGGNR
HHHHHHCCCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCEEEEEECCEEEEEEEEECCCCH
RALEALRARVEHRRFELEGARLTLAANIVTTAITQAMLAAQIDASEAILRAQDEQLALAR
HHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
ERERLGQASPDEVLTLQTQVEQTRASLPPLRQRLDETAHLLAVLAGRAPGAGDMPSFSLE
HHHHCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EFTLPAELPLVVPSELARRRPDIRAAEALMHAANAEYGVAVARLYPQLKLSANLGSQALS
HCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHHHH
TGALFGSGSAVWSLVGQLTQPLFNPGLPAEKRASLAAFEAASANYQGVVLEALRDVADVL
HCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RALDHDASALAALASADEAAQGALESMRRRYALGAASYLDILTAEQQAQQTRVNLVAAQA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLVDNAALYQALGGGWTETN
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]