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The map label for this gene is ompR [H]

Identifier: 74317305

GI number: 74317305

Start: 1355283

End: 1355981

Strand: Direct

Name: ompR [H]

Synonym: Tbd_1287

Alternate gene names: 74317305

Gene position: 1355283-1355981 (Clockwise)

Preceding gene: 74317304

Following gene: 74317306

Centisome position: 46.58

GC content: 68.53

Gene sequence:

>699_bases
ATGGAGAGCAAGCGCATTTTAGTAGTGGACGACGACCAGGAACTGCTCGACATGGTCTGCCGTTACCTCGGTGAAAACGG
CCTCGACGCCCACGCGGCGGCCGACAGCGTGCACATGGACGCCTGGCTGGCGAGCAGCAGGCCTGACCTGATCGTGCTCG
ACGTGATGCTCCCCGGCGAAGATGGCCTCTCGGTCGTGAAGCGGCTCAAGTCGCGGCTCGACGTCCCGGTCCTGATGCTC
TCGGCGCGCAGCTCGGACGTCGACCGCATACTCGGCCTGGAAATGGGCGCCGACGACTACCTGACCAAGCCGTTCCACCC
GCGCGAGCTGCTCGCCCGCATCCATGCGCGCCTGCGCAGGTCGCCCGCCCCGCGGCAGGAAGACGCGCTCGAGGCGGGGT
CTTTCCGCCTCGATTTCGTGCGGCGTGACGCCTACAAGCACGGCCAGCCACTCGCGCTGTCGACCGCGGACTTCTCGCTG
CTGTCGCTCCTGATGCGGCATAGCCACCGGGTTCTCGACCGCACCCAGCTCGTCGACCTGGCGTCGGCGATGGAGCGCAT
GCCGTTCAACCGCTCGATCGACGTCCGCGTCGCGCGGCTGCGCCGCAAGATCGAGGACGACCCGGCGCAGCCGCGCTACA
TCCGCACCGTGCGCGGCAGCGGCTACCTGTTCGTGCCCGACGGTGGCGACGAGCGGTGA

Upstream 100 bases:

>100_bases
TTCCGGGGCTTCTTTTTTTTCTCAGCTTATCCCTCGCTGCCGCCCGCGGTCCCTGCGCCGCGGGCGGCGCGCCTGCGTGA
ACACCGTGATACATCCCCCT

Downstream 100 bases:

>100_bases
AGCTGCTGCCAGGCAGTTTTTACTATCGAACCGCGGCGGCGCTGTTCATCGCCACGCTGGCGAGTTCGGTCCTGCTCGTC
GGCATCGGCTGGCTGCTGGT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MESKRILVVDDDQELLDMVCRYLGENGLDAHAAADSVHMDAWLASSRPDLIVLDVMLPGEDGLSVVKRLKSRLDVPVLML
SARSSDVDRILGLEMGADDYLTKPFHPRELLARIHARLRRSPAPRQEDALEAGSFRLDFVRRDAYKHGQPLALSTADFSL
LSLLMRHSHRVLDRTQLVDLASAMERMPFNRSIDVRVARLRRKIEDDPAQPRYIRTVRGSGYLFVPDGGDER

Sequences:

>Translated_232_residues
MESKRILVVDDDQELLDMVCRYLGENGLDAHAAADSVHMDAWLASSRPDLIVLDVMLPGEDGLSVVKRLKSRLDVPVLML
SARSSDVDRILGLEMGADDYLTKPFHPRELLARIHARLRRSPAPRQEDALEAGSFRLDFVRRDAYKHGQPLALSTADFSL
LSLLMRHSHRVLDRTQLVDLASAMERMPFNRSIDVRVARLRRKIEDDPAQPRYIRTVRGSGYLFVPDGGDER
>Mature_232_residues
MESKRILVVDDDQELLDMVCRYLGENGLDAHAAADSVHMDAWLASSRPDLIVLDVMLPGEDGLSVVKRLKSRLDVPVLML
SARSSDVDRILGLEMGADDYLTKPFHPRELLARIHARLRRSPAPRQEDALEAGSFRLDFVRRDAYKHGQPLALSTADFSL
LSLLMRHSHRVLDRTQLVDLASAMERMPFNRSIDVRVARLRRKIEDDPAQPRYIRTVRGSGYLFVPDGGDER

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=48.2905982905983, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=40, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=40.174672489083, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=35.6828193832599, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=37.117903930131, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=31.7796610169492, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=30.6382978723404, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=36.7256637168142, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.4841628959276, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=33.9366515837104, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=35.1598173515982, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.2678571428571, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=30.1310043668122, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=33.0434782608696, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26282; Mature: 26282

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKRILVVDDDQELLDMVCRYLGENGLDAHAAADSVHMDAWLASSRPDLIVLDVMLPGE
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHCCCCCCEEEEEEEECCC
DGLSVVKRLKSRLDVPVLMLSARSSDVDRILGLEMGADDYLTKPFHPRELLARIHARLRR
CCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHC
SPAPRQEDALEAGSFRLDFVRRDAYKHGQPLALSTADFSLLSLLMRHSHRVLDRTQLVDL
CCCCCCHHHHHCCCEEHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAMERMPFNRSIDVRVARLRRKIEDDPAQPRYIRTVRGSGYLFVPDGGDER
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MESKRILVVDDDQELLDMVCRYLGENGLDAHAAADSVHMDAWLASSRPDLIVLDVMLPGE
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHCCCCCCEEEEEEEECCC
DGLSVVKRLKSRLDVPVLMLSARSSDVDRILGLEMGADDYLTKPFHPRELLARIHARLRR
CCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHC
SPAPRQEDALEAGSFRLDFVRRDAYKHGQPLALSTADFSLLSLLMRHSHRVLDRTQLVDL
CCCCCCHHHHHCCCEEHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAMERMPFNRSIDVRVARLRRKIEDDPAQPRYIRTVRGSGYLFVPDGGDER
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]