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The map label for this gene is flhA [H]

Identifier: 74317195

GI number: 74317195

Start: 1236460

End: 1238538

Strand: Direct

Name: flhA [H]

Synonym: Tbd_1177

Alternate gene names: 74317195

Gene position: 1236460-1238538 (Clockwise)

Preceding gene: 74317194

Following gene: 74317196

Centisome position: 42.49

GC content: 67.77

Gene sequence:

>2079_bases
ATGAACGCGCAAGGCGTGATGCTCATGGGCATGCCGGTCAATCGCGTCGCGGTGCCGCTGCTGGTGCTGCTGATCCTGGC
GATGATGGTGCTGCCGCTGCCCACCTTCATGCTCGACGTGCTGTTCACGCTCAACATCGCGCTCGCGATGATCGTGCTGC
TCGTCAGCCTCAACGCGCGCCGCCCGCTCGATTTCTCGGTCTTTCCGACCGTGCTGCTGCTGACGACGCTGCTGCGGCTT
TCGCTCAACGTCGCGTCGACGCGCATCATCCTGATGCAGGGGCATACCGGCCCGGATGCGGCCGGCAAGGTGATCGAGTC
GTTCGGCAATTTTCTCGTCGGGGGCAACATCGCGGTCGGCTTCGTCGTTTTCCTGATACTCGTCATCATCAATTTCGTCG
TCATCACCAAGGGCGCGGGACGGATCGCCGAGGTCGCGGCGCGCTTCACGCTGGACTCGATGCCCGGCAAGCAACTCGCC
GTCGACGCCGATCTCAACGCCGGCTTCGTCGACGAATCGGAAGCGCGCATGCGTCGCGCCGAGATCGGCCGCGAGGCCGA
CTTCTACGGGGCGATGGACGGCGCGTCGAAGTTCGTGCGCGGCGACGCGATCGCCGGCATGATCATCCTGCTCGTCAACC
TGATCGGCGGCATCGCGGTCGGCCTCTTGCAGCACGATCTCGGCGTCGGCGAGGCGCTCGCGCGCTACGCGCTGTTGACC
GTTGGCGACGGCCTGGTCACGCAGATTCCCGCGTTGATCATCTCGACCGCGGCGGGCATCGTCGTCAGCCGCGCGTCGAG
CGAGCAGGATTTGTCGCGAGAATTCTCGACCCAGATTTTCGGTCGGCCGCAGACCCTTTACGTCGCCGCCGCGGTGCTCG
CGGCGCTCGGCGTGATTCCCGGAACCCCGCACGTCGCGTTTCTGACGATCGCGGCCGTCCTCGCGGCCCTCGCGCTCTGG
CTCACACGGCACCGGGAAAGCGCCGCTTTCGACAGCACGCCGCTGCCGCCGATCGAAGAAGAGGCCCTCCCGGTCGATGT
GACCTGGGACGACATTCCGCCCGTCGACGTCCTCGCGCTCGAGGTGGGCTACCGGCTGATACCGCTCGTCGACCGCAACC
AGGGCGGTGCGGCGCTCACGCGCATCACCGAGTCGCGCCGTCGTTTTGCGACCGACATGGGCCTCGTCGTGCCGCTCATC
CGCGTGCGCGACAACCTCGACCTCAAGCCCAACACCTTCCGCATCACGCTGAAGGGCGTCGACGTCGCGCACGGCGAGAT
GCCGACCGGCCAGATCCTCGCGGTCGACACGGGCGACGTCCTTGGCCGTATCGACGGCACGCCGGGCGTCGACCCGCTGA
TGCATCTCCCGGGCGTCTGGATCGACGCGGCGCGCGTGGAGGAAGCCGAACTGCGCGGCTTCGTCGTGCTCGAACCGGCC
GAACTGATCGCCCGCCAGGTCGAGGCCGTCTTCCGCCAGCACGCGCCGGAGCTGCTCGGCCGGACCGAGGTCCAGCAGCT
CCTCGATGCGCTCGCGCGCAGCCATCCCGGGCTCGTCGAGGACGTGACGCCGCGCCATCTGCCCCTGACCACGGTGCAGG
CCATCCTGCAGCAACTGATCGCCGAGAACGTCCCGATCCGCGATACCCGCACCTTGTTCGAGACGCTCGCGGCGCGGGCG
CCCAAAACGCAGGACATCGACGATCTCGTCGAAACCGTGCGCGCGGCGCTCGGCCGCAGCATCGTCGATCGCCTGTTCGA
GGGCAGCGACACGTTGCTCGTCATCGGTCTCGCGCCGACGACCGAAAGCCGTCTGCTCTATGAAATGGGCGACGAGGGCG
AGGCCTTGTTGGCGCCGAGCACCCTCGACGCGCTGAACGGTGCGGCCGAGCAGGCGGTCGCCGAACACGAGGCTGGAGGC
CATCCGCCGGTGTTGCTGACCTCGCCCGGCCTGCGTGCGATTCTCTCGCGGCTGCTGCGTCGCACGCTGCCGCGGCTCGC
GGTGATCGCCTACGCCGAGGTACCGGCCGACAAGACGGTCCAGGTGAACGTTGAATTGAGCATCGGGGAGACCCCATGA

Upstream 100 bases:

>100_bases
ATCCCGAGATCCGGGCGCAGTTGCGTGGACGGCAACAGCAGGCGGGCGCAAGGCCCCGGCCCGCAACTGCTGAGCACCCC
GTGATCGACGAGGTGATCGG

Downstream 100 bases:

>100_bases
GCGTACAGACATTCGTCGCCACCACCGCACGCGAGGGGTTGGCGCGCGTACGGCAGGCGCTCGGCGACGACGCCGTCGTG
CTGTCGACGCGTCCGCATCC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MNAQGVMLMGMPVNRVAVPLLVLLILAMMVLPLPTFMLDVLFTLNIALAMIVLLVSLNARRPLDFSVFPTVLLLTTLLRL
SLNVASTRIILMQGHTGPDAAGKVIESFGNFLVGGNIAVGFVVFLILVIINFVVITKGAGRIAEVAARFTLDSMPGKQLA
VDADLNAGFVDESEARMRRAEIGREADFYGAMDGASKFVRGDAIAGMIILLVNLIGGIAVGLLQHDLGVGEALARYALLT
VGDGLVTQIPALIISTAAGIVVSRASSEQDLSREFSTQIFGRPQTLYVAAAVLAALGVIPGTPHVAFLTIAAVLAALALW
LTRHRESAAFDSTPLPPIEEEALPVDVTWDDIPPVDVLALEVGYRLIPLVDRNQGGAALTRITESRRRFATDMGLVVPLI
RVRDNLDLKPNTFRITLKGVDVAHGEMPTGQILAVDTGDVLGRIDGTPGVDPLMHLPGVWIDAARVEEAELRGFVVLEPA
ELIARQVEAVFRQHAPELLGRTEVQQLLDALARSHPGLVEDVTPRHLPLTTVQAILQQLIAENVPIRDTRTLFETLAARA
PKTQDIDDLVETVRAALGRSIVDRLFEGSDTLLVIGLAPTTESRLLYEMGDEGEALLAPSTLDALNGAAEQAVAEHEAGG
HPPVLLTSPGLRAILSRLLRRTLPRLAVIAYAEVPADKTVQVNVELSIGETP

Sequences:

>Translated_692_residues
MNAQGVMLMGMPVNRVAVPLLVLLILAMMVLPLPTFMLDVLFTLNIALAMIVLLVSLNARRPLDFSVFPTVLLLTTLLRL
SLNVASTRIILMQGHTGPDAAGKVIESFGNFLVGGNIAVGFVVFLILVIINFVVITKGAGRIAEVAARFTLDSMPGKQLA
VDADLNAGFVDESEARMRRAEIGREADFYGAMDGASKFVRGDAIAGMIILLVNLIGGIAVGLLQHDLGVGEALARYALLT
VGDGLVTQIPALIISTAAGIVVSRASSEQDLSREFSTQIFGRPQTLYVAAAVLAALGVIPGTPHVAFLTIAAVLAALALW
LTRHRESAAFDSTPLPPIEEEALPVDVTWDDIPPVDVLALEVGYRLIPLVDRNQGGAALTRITESRRRFATDMGLVVPLI
RVRDNLDLKPNTFRITLKGVDVAHGEMPTGQILAVDTGDVLGRIDGTPGVDPLMHLPGVWIDAARVEEAELRGFVVLEPA
ELIARQVEAVFRQHAPELLGRTEVQQLLDALARSHPGLVEDVTPRHLPLTTVQAILQQLIAENVPIRDTRTLFETLAARA
PKTQDIDDLVETVRAALGRSIVDRLFEGSDTLLVIGLAPTTESRLLYEMGDEGEALLAPSTLDALNGAAEQAVAEHEAGG
HPPVLLTSPGLRAILSRLLRRTLPRLAVIAYAEVPADKTVQVNVELSIGETP
>Mature_692_residues
MNAQGVMLMGMPVNRVAVPLLVLLILAMMVLPLPTFMLDVLFTLNIALAMIVLLVSLNARRPLDFSVFPTVLLLTTLLRL
SLNVASTRIILMQGHTGPDAAGKVIESFGNFLVGGNIAVGFVVFLILVIINFVVITKGAGRIAEVAARFTLDSMPGKQLA
VDADLNAGFVDESEARMRRAEIGREADFYGAMDGASKFVRGDAIAGMIILLVNLIGGIAVGLLQHDLGVGEALARYALLT
VGDGLVTQIPALIISTAAGIVVSRASSEQDLSREFSTQIFGRPQTLYVAAAVLAALGVIPGTPHVAFLTIAAVLAALALW
LTRHRESAAFDSTPLPPIEEEALPVDVTWDDIPPVDVLALEVGYRLIPLVDRNQGGAALTRITESRRRFATDMGLVVPLI
RVRDNLDLKPNTFRITLKGVDVAHGEMPTGQILAVDTGDVLGRIDGTPGVDPLMHLPGVWIDAARVEEAELRGFVVLEPA
ELIARQVEAVFRQHAPELLGRTEVQQLLDALARSHPGLVEDVTPRHLPLTTVQAILQQLIAENVPIRDTRTLFETLAARA
PKTQDIDDLVETVRAALGRSIVDRLFEGSDTLLVIGLAPTTESRLLYEMGDEGEALLAPSTLDALNGAAEQAVAEHEAGG
HPPVLLTSPGLRAILSRLLRRTLPRLAVIAYAEVPADKTVQVNVELSIGETP

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=668, Percent_Identity=50.8982035928144, Blast_Score=654, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74038; Mature: 74038

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQGVMLMGMPVNRVAVPLLVLLILAMMVLPLPTFMLDVLFTLNIALAMIVLLVSLNAR
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPLDFSVFPTVLLLTTLLRLSLNVASTRIILMQGHTGPDAAGKVIESFGNFLVGGNIAVG
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCEEECCCHHHH
FVVFLILVIINFVVITKGAGRIAEVAARFTLDSMPGKQLAVDADLNAGFVDESEARMRRA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHH
EIGREADFYGAMDGASKFVRGDAIAGMIILLVNLIGGIAVGLLQHDLGVGEALARYALLT
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VGDGLVTQIPALIISTAAGIVVSRASSEQDLSREFSTQIFGRPQTLYVAAAVLAALGVIP
CCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
GTPHVAFLTIAAVLAALALWLTRHRESAAFDSTPLPPIEEEALPVDVTWDDIPPVDVLAL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
EVGYRLIPLVDRNQGGAALTRITESRRRFATDMGLVVPLIRVRDNLDLKPNTFRITLKGV
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
DVAHGEMPTGQILAVDTGDVLGRIDGTPGVDPLMHLPGVWIDAARVEEAELRGFVVLEPA
EEECCCCCCCCEEEEECCCHHEECCCCCCCCHHHHCCCCEEEHHHCCHHHHCCEEEECHH
ELIARQVEAVFRQHAPELLGRTEVQQLLDALARSHPGLVEDVTPRHLPLTTVQAILQQLI
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
AENVPIRDTRTLFETLAARAPKTQDIDDLVETVRAALGRSIVDRLFEGSDTLLVIGLAPT
HCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TESRLLYEMGDEGEALLAPSTLDALNGAAEQAVAEHEAGGHPPVLLTSPGLRAILSRLLR
CCCCHHEECCCCCCEEECCCHHHHHCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
RTLPRLAVIAYAEVPADKTVQVNVELSIGETP
HHHHHHHHHEEEECCCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MNAQGVMLMGMPVNRVAVPLLVLLILAMMVLPLPTFMLDVLFTLNIALAMIVLLVSLNAR
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPLDFSVFPTVLLLTTLLRLSLNVASTRIILMQGHTGPDAAGKVIESFGNFLVGGNIAVG
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCEEECCCHHHH
FVVFLILVIINFVVITKGAGRIAEVAARFTLDSMPGKQLAVDADLNAGFVDESEARMRRA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHH
EIGREADFYGAMDGASKFVRGDAIAGMIILLVNLIGGIAVGLLQHDLGVGEALARYALLT
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VGDGLVTQIPALIISTAAGIVVSRASSEQDLSREFSTQIFGRPQTLYVAAAVLAALGVIP
CCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
GTPHVAFLTIAAVLAALALWLTRHRESAAFDSTPLPPIEEEALPVDVTWDDIPPVDVLAL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
EVGYRLIPLVDRNQGGAALTRITESRRRFATDMGLVVPLIRVRDNLDLKPNTFRITLKGV
HHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEC
DVAHGEMPTGQILAVDTGDVLGRIDGTPGVDPLMHLPGVWIDAARVEEAELRGFVVLEPA
EEECCCCCCCCEEEEECCCHHEECCCCCCCCHHHHCCCCEEEHHHCCHHHHCCEEEECHH
ELIARQVEAVFRQHAPELLGRTEVQQLLDALARSHPGLVEDVTPRHLPLTTVQAILQQLI
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
AENVPIRDTRTLFETLAARAPKTQDIDDLVETVRAALGRSIVDRLFEGSDTLLVIGLAPT
HCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TESRLLYEMGDEGEALLAPSTLDALNGAAEQAVAEHEAGGHPPVLLTSPGLRAILSRLLR
CCCCHHEECCCCCCEEECCCHHHHHCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
RTLPRLAVIAYAEVPADKTVQVNVELSIGETP
HHHHHHHHHEEEECCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]