Click here to switch to the map view.

The map label for this gene is hscB [H]

Identifier: 74317185

GI number: 74317185

Start: 1220114

End: 1220641

Strand: Direct

Name: hscB [H]

Synonym: Tbd_1167

Alternate gene names: 74317185

Gene position: 1220114-1220641 (Clockwise)

Preceding gene: 74317184

Following gene: 74317186

Centisome position: 41.93

GC content: 63.26

Gene sequence:

>528_bases
ATGAATTTCACCCGCAACCATTTCGAACTGTTCGGTCTGCCCACGGCGTATGCACTCGACCGCGACCGCCTCGACGCGGC
TTACCGCGAGTTGCAGAATACCGTGCATCCCGACCGTTTCGCCGCCCAGCCCGAAGCCGAACAGCGCGTCGCGATGCAGT
GGGCGACGCAGGTGAACGAGGCTTATCGCACCTTGCGCGACCCGGTCAGCCGCGGCGTGTACCTGCTGCGCTTGCAGGGC
ATCGATGCGCTCGACGCGAGCAATACCAAAATGGCCCCGGCATTCCTGATGCAGCAGATGGAATGGCGCGAGGCGATCGA
CGCTGCGCGGGTCGACCAGAGCATCGAAGCGCTCGACGCGCTGACCGATGAGTTGCGCAGCGCGCATCGTCGCATCGAGG
CCGAACTCGCGAGCCTGATCGACACCGCGAAGGATTTCGCCGCGGCGTCGGAAGCGGTGCGCCAACTGCGGTTCATGGAC
AAACTCATCGCCGAGCTTGGCGACGTTTACGAAGAATTGGAAGCTTAG

Upstream 100 bases:

>100_bases
GTTCGGGGGTCAGGGTTCTTGTGCGGCCCATGGCCGCGCCTTTCGGAATGCGCAGCACAAGGCCCCCTGAATCGTGATCC
CTGAATCCTGATCCCTGAAA

Downstream 100 bases:

>100_bases
GCATGGCCCTGCTGCAGATTTCCGAACCTGGCATGTCGAGCGCGCCGCATCAGCATCGCCTCGCCGTCGGCATCGACCTC
GGGACGACCAACACGCTCGT

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNFTRNHFELFGLPTAYALDRDRLDAAYRELQNTVHPDRFAAQPEAEQRVAMQWATQVNEAYRTLRDPVSRGVYLLRLQG
IDALDASNTKMAPAFLMQQMEWREAIDAARVDQSIEALDALTDELRSAHRRIEAELASLIDTAKDFAAASEAVRQLRFMD
KLIAELGDVYEELEA

Sequences:

>Translated_175_residues
MNFTRNHFELFGLPTAYALDRDRLDAAYRELQNTVHPDRFAAQPEAEQRVAMQWATQVNEAYRTLRDPVSRGVYLLRLQG
IDALDASNTKMAPAFLMQQMEWREAIDAARVDQSIEALDALTDELRSAHRRIEAELASLIDTAKDFAAASEAVRQLRFMD
KLIAELGDVYEELEA
>Mature_175_residues
MNFTRNHFELFGLPTAYALDRDRLDAAYRELQNTVHPDRFAAQPEAEQRVAMQWATQVNEAYRTLRDPVSRGVYLLRLQG
IDALDASNTKMAPAFLMQQMEWREAIDAARVDQSIEALDALTDELRSAHRRIEAELASLIDTAKDFAAASEAVRQLRFMD
KLIAELGDVYEELEA

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=159, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1788876, Length=175, Percent_Identity=36.5714285714286, Blast_Score=102, Evalue=1e-23,
Organism=Drosophila melanogaster, GI161084223, Length=155, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19961; Mature: 19961

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFTRNHFELFGLPTAYALDRDRLDAAYRELQNTVHPDRFAAQPEAEQRVAMQWATQVNE
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHH
AYRTLRDPVSRGVYLLRLQGIDALDASNTKMAPAFLMQQMEWREAIDAARVDQSIEALDA
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDELRSAHRRIEAELASLIDTAKDFAAASEAVRQLRFMDKLIAELGDVYEELEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFTRNHFELFGLPTAYALDRDRLDAAYRELQNTVHPDRFAAQPEAEQRVAMQWATQVNE
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHH
AYRTLRDPVSRGVYLLRLQGIDALDASNTKMAPAFLMQQMEWREAIDAARVDQSIEALDA
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDELRSAHRRIEAELASLIDTAKDFAAASEAVRQLRFMDKLIAELGDVYEELEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA