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The map label for this gene is htpG

Identifier: 74317096

GI number: 74317096

Start: 1137684

End: 1139585

Strand: Reverse

Name: htpG

Synonym: Tbd_1078

Alternate gene names: 74317096

Gene position: 1139585-1137684 (Counterclockwise)

Preceding gene: 74317098

Following gene: 74317095

Centisome position: 39.16

GC content: 62.93

Gene sequence:

>1902_bases
ATGTCCGCCACCAGCAGCAAAGAAACCCTGGGCTTTCAAGCCGAAGTCAAACAGCTCCTGCAGCTGATGATCCATTCCTT
GTATTCGAACAAGGACATATTCCTCCGCGAACTGATCTCCAACGCCTCCGACGCCGCCGACAAGCTGCGCTTCGAAGCCT
TGTCGGACGCCGCGCTGTTCGAGAACGACCCCGAGCTCAAGATCCGCATCGCCTTCGACCGCGACGCGCGCACGCTCACC
ATTTCCGACAACGGCATCGGCATGAGCCGGCAGGAGGTCATCGACCACATCGGCACGATCGCCAAGTCCGGCACGCGCGA
ATTCTTCAGCCAGCTTTCCGGCGACCAGAAGAAGGACGCCGCGCTGATCGGCCAGTTCGGCGTCGGCTTCTATTCCGCCT
TCATCGTCGCCGACCGCGTCACGCTCACGACCCGCCGCGCCGGCCTTACCGCCGAGCACGGTGTGCGCTGGGAATCCGAG
GGCGCCGGCGACTACACGCTGGAAACGGTCGAGAAGCCCCAACGCGGCACCGAGATCGTGCTGCATCTGCGTGAAGGCGA
GGACGAATTCCTCTCCGACTGGAAGATCAAGTCGGTCATCCGCACCTATTCCGACCACATCACGCTGCCGATCGTGATGA
AGAAGACCGAATGGAAGGACGGCGTCGAGACGCCGACCGACGAGGACGAAACGGTCAACAAAGCCTCGGCCTTGTGGGCT
CGCCCGAAGAAGGACATCAGCGACGACGAGTACAACGAGTTCTACAAGCACGTCGCCCACGACTTCGAGCCGCCGCTCGC
CTGGTCGCATAACCGCGTCGAGGGCAAGCAGGAATACATCTCCCTGCTCTACGTGCCCTCGCACGCGCCGTTCGACCTCT
ACGACCGAGAGAAGCGCCACGGCATCAAACTTTATGTGCGCCGCGTCTTCATCATGGACGACGCCGAGCAGCTGATGCCG
CAATACCTGCGCTTCGTCCGCGGCGTCATCGACTCGGCCGACCTGCCCTTGAACGTCTCGCGCGAAATCCTGCAGTCGAG
CCGCGACATCGACGCCATCAAGAACGGCTCGGTGAAGAAGGTGCTCGGCATGCTCGAAGACCTCGCCGAGAACCAGCCCG
AAAAATACGTCGAGTTCTGGAAAGAGTTCGGCAAGGTCATGAAGGAAGGCCCGGGCGAGGACTTCGCCAACAAGGAGAAG
ATCGCCGGCCTGCTCCGCTTCGCCTCCACCCACACCGACACCGACGCGCAGGTCGTGTCGCTCAAGGACTACGTCGGCCG
CATGAAGGAAGGCCAGACCGCGATCTACTACATCACCGCCGACAGCTTCGCCGCCGCCCAGCACAGCCCGCACCTCGAAA
TCTTCCGCAAGAAAGGCATCGAAGTCCTGCTGCTGTCCGACCGCGTCGACGAATGGCTCACCGGCAACCTGCATGAGTTC
GACGGCAAGCCGCTCAAGTCCGTCGCCAAGGGCGGCCTCGACCTCGGCGAACTCGAAGACGAAGCCGAGAAGACCGCGCA
GAAGGAAGCCGAGGAGTCGATGAAGCCGCTGGTCGAGCGCATCAAGGCCATGCTCGGCGAGCGCGTCAAGGACGTCCGCG
TCACCCACCGCCTCACCGATTCGCCCGCCTGCCTCGTCACCGGCGAAGGCGACATGAGCGCCAACCTCGAACGGCTATTG
AAAGCCGCCGGCCAAGCCGCGCCCACCGTGAAGCCCACGCTGGAGATCAACCCGTCGCACGCGTTGGTCACGCGGCTCGA
CAGCGAATCCGACGAAGACCGCTTCAAGGACTGGGCCAACCTGCTGTTCGAGCAGGCGCTGCTGGCGGAAGGTGGACAGC
TCGACGATCCGGCGAGTTTTGTGCGGCGGTTGAATGGGTTGCTGGCGATGTTGCCGGGTTGA

Upstream 100 bases:

>100_bases
CGCACCGAGGCGCTGAGCATGGGGGGCTTGAAACTCGGCGCCGCCGCCCCCATCTCCGCTCCCACCTTGTTTGTACGTGT
AACCAACGGGAGATAAAGGC

Downstream 100 bases:

>100_bases
GGACGCAAGAGCCGTTCGTGTTGAGCTTGTCGAAACACGAATGACCTTAATTGTTGTATCCAACGCGACTGAGCAATCAG
TCGCGTTTTTTATTGCTTTG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALFENDPELKIRIAFDRDARTLT
ISDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDAALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESE
GAGDYTLETVEKPQRGTEIVLHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWA
RPKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRHGIKLYVRRVFIMDDAEQLMP
QYLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKKVLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEK
IAGLLRFASTHTDTDAQVVSLKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEF
DGKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTDSPACLVTGEGDMSANLERLL
KAAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWANLLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG

Sequences:

>Translated_633_residues
MSATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALFENDPELKIRIAFDRDARTLT
ISDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDAALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESE
GAGDYTLETVEKPQRGTEIVLHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWA
RPKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRHGIKLYVRRVFIMDDAEQLMP
QYLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKKVLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEK
IAGLLRFASTHTDTDAQVVSLKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEF
DGKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTDSPACLVTGEGDMSANLERLL
KAAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWANLLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG
>Mature_632_residues
SATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALFENDPELKIRIAFDRDARTLTI
SDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDAALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESEG
AGDYTLETVEKPQRGTEIVLHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWAR
PKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRHGIKLYVRRVFIMDDAEQLMPQ
YLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKKVLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEKI
AGLLRFASTHTDTDAQVVSLKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEFD
GKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTDSPACLVTGEGDMSANLERLLK
AAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWANLLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=687, Percent_Identity=38.5735080058224, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=634, Percent_Identity=35.9621451104101, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=41.9902912621359, Blast_Score=302, Evalue=6e-82,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=41.7874396135266, Blast_Score=299, Evalue=4e-81,
Organism=Homo sapiens, GI20149594, Length=207, Percent_Identity=45.4106280193237, Blast_Score=188, Evalue=1e-47,
Organism=Escherichia coli, GI1786679, Length=623, Percent_Identity=64.6869983948636, Blast_Score=836, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=674, Percent_Identity=40.8011869436202, Blast_Score=487, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=39.1111111111111, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115535205, Length=650, Percent_Identity=34.3076923076923, Blast_Score=324, Evalue=8e-89,
Organism=Caenorhabditis elegans, GI115535167, Length=426, Percent_Identity=36.150234741784, Blast_Score=256, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=40.500736377025, Blast_Score=479, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6325016, Length=685, Percent_Identity=39.8540145985401, Blast_Score=475, Evalue=1e-135,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=39.766081871345, Blast_Score=481, Evalue=1e-136,
Organism=Drosophila melanogaster, GI21357739, Length=686, Percent_Identity=38.7755102040816, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=644, Percent_Identity=35.0931677018634, Blast_Score=364, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_THIDA (Q3SJW8)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314836.1
- ProteinModelPortal:   Q3SJW8
- SMR:   Q3SJW8
- STRING:   Q3SJW8
- GeneID:   3673771
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1078
- NMPDR:   fig|292415.3.peg.1078
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q3SJW8
- ProtClustDB:   PRK05218
- BioCyc:   TDEN292415:TBD_1078-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71168; Mature: 71037

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALF
CCCCCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ENDPELKIRIAFDRDARTLTISDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
ALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESEGAGDYTLETVEKPQRGTEIV
HHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHCCCCCCCCCCCCCHHHHHCCCCCCEEE
LHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWA
EEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
RPKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRH
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHC
GIKLYVRRVFIMDDAEQLMPQYLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKK
CHHEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCCCHHH
VLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEKIAGLLRFASTHTDTDAQVVS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEEE
LKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEF
HHHHHHHHCCCCEEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECCHHHHHHCCCCHHC
DGKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTD
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPACLVTGEGDMSANLERLLKAAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWAN
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHEECCCCCCHHHHHHHHH
LLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
SATSSKETLGFQAEVKQLLQLMIHSLYSNKDIFLRELISNASDAADKLRFEALSDAALF
CCCCCCHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ENDPELKIRIAFDRDARTLTISDNGIGMSRQEVIDHIGTIAKSGTREFFSQLSGDQKKDA
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
ALIGQFGVGFYSAFIVADRVTLTTRRAGLTAEHGVRWESEGAGDYTLETVEKPQRGTEIV
HHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHCCCCCCCCCCCCCHHHHHCCCCCCEEE
LHLREGEDEFLSDWKIKSVIRTYSDHITLPIVMKKTEWKDGVETPTDEDETVNKASALWA
EEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
RPKKDISDDEYNEFYKHVAHDFEPPLAWSHNRVEGKQEYISLLYVPSHAPFDLYDREKRH
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCHHHHHHC
GIKLYVRRVFIMDDAEQLMPQYLRFVRGVIDSADLPLNVSREILQSSRDIDAIKNGSVKK
CHHEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHCCCCHHH
VLGMLEDLAENQPEKYVEFWKEFGKVMKEGPGEDFANKEKIAGLLRFASTHTDTDAQVVS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHEEE
LKDYVGRMKEGQTAIYYITADSFAAAQHSPHLEIFRKKGIEVLLLSDRVDEWLTGNLHEF
HHHHHHHHCCCCEEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECCHHHHHHCCCCHHC
DGKPLKSVAKGGLDLGELEDEAEKTAQKEAEESMKPLVERIKAMLGERVKDVRVTHRLTD
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPACLVTGEGDMSANLERLLKAAGQAAPTVKPTLEINPSHALVTRLDSESDEDRFKDWAN
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHEECCCCCCHHHHHHHHH
LLFEQALLAEGGQLDDPASFVRRLNGLLAMLPG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA