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The map label for this gene is moaE [H]

Identifier: 74317045

GI number: 74317045

Start: 1094197

End: 1094652

Strand: Direct

Name: moaE [H]

Synonym: Tbd_1027

Alternate gene names: 74317045

Gene position: 1094197-1094652 (Clockwise)

Preceding gene: 74317044

Following gene: 74317046

Centisome position: 37.6

GC content: 70.18

Gene sequence:

>456_bases
ATGAAAATCGCGGTACAGAACGAAGCCTTCGATCTCGGCAGCGAAGTCGCGGCGCTGACGCACGGCCGGCGCGACGTCGG
CGCGGTCGCGAGCTTCGTCGGACTCGCGCGCGACATCAACGAAGGCAGCGGCGTCGCCGCGATGACGCTCGAACATTACC
CGGGCATGACCGAGAAGGCGCTCGCCGCGCTGGTCGACGAGGCCTGCGCGCGCTGGGCCTTGCTCGACGTGAGCGTGGTC
CATCGCGTCGGGCGTCTGCTGCCGGGCGACCCGATCGTGCTCGTCGCGGTCGCGAGCGCCCACCGCGGTGAGGCGTTCGC
CGCGTGCGAATTCATCATGGACGCGCTGAAGACGCGTGCGCCGTTCTGGAAGAAGGAAGAGACGCCGGACGGCGAGCGCT
GGGTCGAGGCGCGCGCCAGCGACGAAGCCGCCGCCGGGCGCTGGGAGAAACGCTGA

Upstream 100 bases:

>100_bases
CTTTCCGTGTCGCGGTCGATCAGGAAATCGTCGCGCTCGACGCGACGCTTGCGGAGGGCGCCGAAGTCGCGATCTTTCCG
CCCGTGACCGGAGGCTAGCC

Downstream 100 bases:

>100_bases
GCGTCGCAGCCGGAGGCAGCGCGTAAGGGGTTCCCAGGGCCGCTTGACATTTGTTCTAACAAGAACTAAATTTGGTTCTG
GTTAGAACAAATTAGCGCCC

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKIAVQNEAFDLGSEVAALTHGRRDVGAVASFVGLARDINEGSGVAAMTLEHYPGMTEKALAALVDEACARWALLDVSVV
HRVGRLLPGDPIVLVAVASAHRGEAFAACEFIMDALKTRAPFWKKEETPDGERWVEARASDEAAAGRWEKR

Sequences:

>Translated_151_residues
MKIAVQNEAFDLGSEVAALTHGRRDVGAVASFVGLARDINEGSGVAAMTLEHYPGMTEKALAALVDEACARWALLDVSVV
HRVGRLLPGDPIVLVAVASAHRGEAFAACEFIMDALKTRAPFWKKEETPDGERWVEARASDEAAAGRWEKR
>Mature_151_residues
MKIAVQNEAFDLGSEVAALTHGRRDVGAVASFVGLARDINEGSGVAAMTLEHYPGMTEKALAALVDEACARWALLDVSVV
HRVGRLLPGDPIVLVAVASAHRGEAFAACEFIMDALKTRAPFWKKEETPDGERWVEARASDEAAAGRWEKR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=108, Percent_Identity=31.4814814814815, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1787003, Length=147, Percent_Identity=59.8639455782313, Blast_Score=174, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21356259, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16271; Mature: 16271

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVQNEAFDLGSEVAALTHGRRDVGAVASFVGLARDINEGSGVAAMTLEHYPGMTEKA
CEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCHHHH
LAALVDEACARWALLDVSVVHRVGRLLPGDPIVLVAVASAHRGEAFAACEFIMDALKTRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PFWKKEETPDGERWVEARASDEAAAGRWEKR
CCCCCCCCCCHHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MKIAVQNEAFDLGSEVAALTHGRRDVGAVASFVGLARDINEGSGVAAMTLEHYPGMTEKA
CEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCHHHH
LAALVDEACARWALLDVSVVHRVGRLLPGDPIVLVAVASAHRGEAFAACEFIMDALKTRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PFWKKEETPDGERWVEARASDEAAAGRWEKR
CCCCCCCCCCHHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]