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The map label for this gene is yciR [C]

Identifier: 74317024

GI number: 74317024

Start: 1073271

End: 1075463

Strand: Direct

Name: yciR [C]

Synonym: Tbd_1006

Alternate gene names: 74317024

Gene position: 1073271-1075463 (Clockwise)

Preceding gene: 74317023

Following gene: 74317025

Centisome position: 36.88

GC content: 60.47

Gene sequence:

>2193_bases
TTGATCGCCTACCTGTGTGCTCCGCACGCGCTCGTGCTTCAGAAAGAGGCCAGCCACCGCCTGCGCCCTAAAGTCTCTCG
GCCCCGCACCCGTTATGTGATCGGACGACTCCACTCTCAACGGGCTGCCGCGCATCCCGCCTCGACGTCCCCCCTAATGT
TTCGATTAAGTCGCTATTACTCGATTGCCAGCCTCGTCGGCATATCGATCGTCGTGGTGGTGCTGTCCTGGTTTTACCGT
CAGCTGGCCATCGAGACCCTGCTCGCACACCAGACCCGTTCCAACGTCGACCTGACCCGTAGCTATGCGAACGCGATCTG
GCACCGGTTCGATGCATTCGTGTCGGCCTCGGGCGAGTGGTCCGCAGAAGATCTCAGGCGACGGCCCGAGGTGGCATCCT
TGCACGCCGCGACCTTGGCGCAGATGCATGGCATGAATGTCGTCAAGGTCAAGGTGTACAACCTGTCCGGGACGACGGTG
TACTCGTCCGAAGCCGGCCAGATCGGCGAGGATAAACACGACAATCCGGGCTTTCTCAGCGCGCGTGCCGGCAAGCCGGC
GAGCGAAATCGTGTTTCGCGACCAGTTTTACGCCTTTGAGGAGGTGATCGCCGATCGCAATCTGATCGCGACCTATCTGC
CGATTCACGAGCACGGCAACGGGCCCGTCAAGGCCGTGTTCGAGGTGTACACGGACGTCACGCCACTGGTCGCGAAAATG
GAGGCGACGCAGACGAAGATCATCACGGGCGTCGTGCTGGCGCTGGCACTGCTTTACCTGTTCCTGTTCTTGATCGTCCG
CCGCGCCGACCAGATCATCACGCGACAGGACCGGGAGCGGCAGGACAACGAGCAGCGGATCCGCCATCAGGCCTTCCACG
ACTCGCTGACGGGCCTGCCGAACCGCAACAGTTTCTTGGAGCACATCTCCGAAGCGATCGACCGGTCGAAACGCTCAGGC
AACCCCGGCGCCTTGTTGTTCCTGGATCTCGACCGCTTCAAGCTGGTCAACGACAGTCTTGGCCACGATGCGGGTGATCA
GTTGCTGCGGATCACCGCTTCGCGGATTCAGAAATGCCTTCGCGAGACCGACATGGCCTTCCGCATGAGCGGGGACGAGT
TCGTGGTCATTCTTGAAAGCGTGGACAAGGGCGAGCACGCCGCGCTGGCCGCGCAGCGCGTCATGCAGGAGATGGCTGTG
CCCATGTCGCTCAGCGGCTGCGAAGTGATCGTAAATGTCAGCATAGGCATCACGACTTTCGCTGGCGACAGCGCCGACGT
TCAGGCCCTGCTGAAAGAAGCGGACTCCGCGATGTATCGCGCCAAGCAGGTCGGCCAAAACCATTACGAGTTCCATACGC
CGGACATGAACAGTGCCGCGCATGAACGGCTATCGATGGAAACGGATTTGCAGCGCGCCCTGCAGAACCAGGAATTCGTC
CTGCATTACCAGCCAAAAATCGACACCGCGACGAAAGCGATCGTCAGTGTCGAGGCGCTGCTACGCTGGAACCATCCCAC
TCGCGGCCTGGTGCTACCGAACACGTTCATACCCTTGCTGGAGGATACCGGACTGATTAACCCGGTCGGCGAATGGGTGC
TGCTTCAGGCGGCCTGCCAGGCGCAGGCCTGGATCGACGCGGGCCTGGAGCCGATACGCATGTCCGTGAACATTTCGGCC
AAGCAGTTCCGTAGCCACATTCTTGTCGAGACGGTACGACGCACGCTCGGCGCGTCGCAACTCGAATCACGCTATCTGGA
GCTCGAACTTACCGAGAGCATGTTCATCGAGAACGCGGAACGCTCGATCCAGATAATGCAGGAATTGAAATGTCTGGGTG
TGAGTCTGTCCATCGATGATTTCGGTTCGGGGTATTCTTCGCTTGCCTATCTCAAGCAGTTTCCGGTCGACTACCTCAAG
ATCGACCGCTCGTTCGTCACCGATCTGGTGTCCAACAAAAAGGATGCGGCCATCGCGGTGGCGATCGCGGCGCTCGCGCA
CAGCCTGGACCTGAAGCTCGTGGCGGAAGGCGTCGAGGATCAGGCCCAGGTCGAGTTCCTCGAAAAACAGGGGTGCCATG
AACTGCAGGGTTATCTGTTCGGTCGCCCGGTTTCCGCCGAAGAACTGGAACAGGTGCTACGCCAAGCGGACCGTGGACAA
GAGGCGCGGCGGCCGGTTGACACGGCCGCGTAA

Upstream 100 bases:

>100_bases
CGACGCTGGCTGCTGGTCCATCCTAAATGAGAGCCAGGGAACCGAGTCGGCGACGCTGGAAATGAGCTGTCTGGCCCTTT
GCGTGCCCTGAAATGATCGG

Downstream 100 bases:

>100_bases
GGCCGCGTTTTTTCGTTACGGGATGCCGTGCATCACCAACAAGTATTTTTTCGCAGGTGACTGAGCACTGAAAAAAAGCG
CCGCCGACTCGACAGTCACA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MIAYLCAPHALVLQKEASHRLRPKVSRPRTRYVIGRLHSQRAAAHPASTSPLMFRLSRYYSIASLVGISIVVVVLSWFYR
QLAIETLLAHQTRSNVDLTRSYANAIWHRFDAFVSASGEWSAEDLRRRPEVASLHAATLAQMHGMNVVKVKVYNLSGTTV
YSSEAGQIGEDKHDNPGFLSARAGKPASEIVFRDQFYAFEEVIADRNLIATYLPIHEHGNGPVKAVFEVYTDVTPLVAKM
EATQTKIITGVVLALALLYLFLFLIVRRADQIITRQDRERQDNEQRIRHQAFHDSLTGLPNRNSFLEHISEAIDRSKRSG
NPGALLFLDLDRFKLVNDSLGHDAGDQLLRITASRIQKCLRETDMAFRMSGDEFVVILESVDKGEHAALAAQRVMQEMAV
PMSLSGCEVIVNVSIGITTFAGDSADVQALLKEADSAMYRAKQVGQNHYEFHTPDMNSAAHERLSMETDLQRALQNQEFV
LHYQPKIDTATKAIVSVEALLRWNHPTRGLVLPNTFIPLLEDTGLINPVGEWVLLQAACQAQAWIDAGLEPIRMSVNISA
KQFRSHILVETVRRTLGASQLESRYLELELTESMFIENAERSIQIMQELKCLGVSLSIDDFGSGYSSLAYLKQFPVDYLK
IDRSFVTDLVSNKKDAAIAVAIAALAHSLDLKLVAEGVEDQAQVEFLEKQGCHELQGYLFGRPVSAEELEQVLRQADRGQ
EARRPVDTAA

Sequences:

>Translated_730_residues
MIAYLCAPHALVLQKEASHRLRPKVSRPRTRYVIGRLHSQRAAAHPASTSPLMFRLSRYYSIASLVGISIVVVVLSWFYR
QLAIETLLAHQTRSNVDLTRSYANAIWHRFDAFVSASGEWSAEDLRRRPEVASLHAATLAQMHGMNVVKVKVYNLSGTTV
YSSEAGQIGEDKHDNPGFLSARAGKPASEIVFRDQFYAFEEVIADRNLIATYLPIHEHGNGPVKAVFEVYTDVTPLVAKM
EATQTKIITGVVLALALLYLFLFLIVRRADQIITRQDRERQDNEQRIRHQAFHDSLTGLPNRNSFLEHISEAIDRSKRSG
NPGALLFLDLDRFKLVNDSLGHDAGDQLLRITASRIQKCLRETDMAFRMSGDEFVVILESVDKGEHAALAAQRVMQEMAV
PMSLSGCEVIVNVSIGITTFAGDSADVQALLKEADSAMYRAKQVGQNHYEFHTPDMNSAAHERLSMETDLQRALQNQEFV
LHYQPKIDTATKAIVSVEALLRWNHPTRGLVLPNTFIPLLEDTGLINPVGEWVLLQAACQAQAWIDAGLEPIRMSVNISA
KQFRSHILVETVRRTLGASQLESRYLELELTESMFIENAERSIQIMQELKCLGVSLSIDDFGSGYSSLAYLKQFPVDYLK
IDRSFVTDLVSNKKDAAIAVAIAALAHSLDLKLVAEGVEDQAQVEFLEKQGCHELQGYLFGRPVSAEELEQVLRQADRGQ
EARRPVDTAA
>Mature_730_residues
MIAYLCAPHALVLQKEASHRLRPKVSRPRTRYVIGRLHSQRAAAHPASTSPLMFRLSRYYSIASLVGISIVVVVLSWFYR
QLAIETLLAHQTRSNVDLTRSYANAIWHRFDAFVSASGEWSAEDLRRRPEVASLHAATLAQMHGMNVVKVKVYNLSGTTV
YSSEAGQIGEDKHDNPGFLSARAGKPASEIVFRDQFYAFEEVIADRNLIATYLPIHEHGNGPVKAVFEVYTDVTPLVAKM
EATQTKIITGVVLALALLYLFLFLIVRRADQIITRQDRERQDNEQRIRHQAFHDSLTGLPNRNSFLEHISEAIDRSKRSG
NPGALLFLDLDRFKLVNDSLGHDAGDQLLRITASRIQKCLRETDMAFRMSGDEFVVILESVDKGEHAALAAQRVMQEMAV
PMSLSGCEVIVNVSIGITTFAGDSADVQALLKEADSAMYRAKQVGQNHYEFHTPDMNSAAHERLSMETDLQRALQNQEFV
LHYQPKIDTATKAIVSVEALLRWNHPTRGLVLPNTFIPLLEDTGLINPVGEWVLLQAACQAQAWIDAGLEPIRMSVNISA
KQFRSHILVETVRRTLGASQLESRYLELELTESMFIENAERSIQIMQELKCLGVSLSIDDFGSGYSSLAYLKQFPVDYLK
IDRSFVTDLVSNKKDAAIAVAIAALAHSLDLKLVAEGVEDQAQVEFLEKQGCHELQGYLFGRPVSAEELEQVLRQADRGQ
EARRPVDTAA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=450, Percent_Identity=38.8888888888889, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI87081921, Length=434, Percent_Identity=34.7926267281106, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=31.0810810810811, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI1790496, Length=262, Percent_Identity=34.7328244274809, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=32.2709163346614, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=34.136546184739, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=247, Percent_Identity=33.6032388663968, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788502, Length=256, Percent_Identity=29.296875, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=254, Percent_Identity=31.496062992126, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788849, Length=453, Percent_Identity=27.1523178807947, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI87082096, Length=472, Percent_Identity=23.3050847457627, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787055, Length=245, Percent_Identity=30.6122448979592, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788381, Length=400, Percent_Identity=28, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI145693134, Length=192, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=34.4632768361582, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786584, Length=198, Percent_Identity=28.7878787878788, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=204, Percent_Identity=31.8627450980392, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=30, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=34.3558282208589, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=30.379746835443, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788956, Length=175, Percent_Identity=33.7142857142857, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=28.4023668639053, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=94, Percent_Identity=32.9787234042553, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=26.0606060606061, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787410, Length=127, Percent_Identity=30.7086614173228, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 81572; Mature: 81572

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAYLCAPHALVLQKEASHRLRPKVSRPRTRYVIGRLHSQRAAAHPASTSPLMFRLSRYY
CEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SIASLVGISIVVVVLSWFYRQLAIETLLAHQTRSNVDLTRSYANAIWHRFDAFVSASGEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SAEDLRRRPEVASLHAATLAQMHGMNVVKVKVYNLSGTTVYSSEAGQIGEDKHDNPGFLS
CHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEE
ARAGKPASEIVFRDQFYAFEEVIADRNLIATYLPIHEHGNGPVKAVFEVYTDVTPLVAKM
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHCHHHHHHHH
EATQTKIITGVVLALALLYLFLFLIVRRADQIITRQDRERQDNEQRIRHQAFHDSLTGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
NRNSFLEHISEAIDRSKRSGNPGALLFLDLDRFKLVNDSLGHDAGDQLLRITASRIQKCL
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RETDMAFRMSGDEFVVILESVDKGEHAALAAQRVMQEMAVPMSLSGCEVIVNVSIGITTF
HHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEE
AGDSADVQALLKEADSAMYRAKQVGQNHYEFHTPDMNSAAHERLSMETDLQRALQNQEFV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LHYQPKIDTATKAIVSVEALLRWNHPTRGLVLPNTFIPLLEDTGLINPVGEWVLLQAACQ
EEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCCCCHHHHHHHHHHHH
AQAWIDAGLEPIRMSVNISAKQFRSHILVETVRRTLGASQLESRYLELELTESMFIENAE
HHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEEHHHHHHHHHH
RSIQIMQELKCLGVSLSIDDFGSGYSSLAYLKQFPVDYLKIDRSFVTDLVSNKKDAAIAV
HHHHHHHHHHHHCCEEEHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHH
AIAALAHSLDLKLVAEGVEDQAQVEFLEKQGCHELQGYLFGRPVSAEELEQVLRQADRGQ
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCH
EARRPVDTAA
HHCCCCCCCC
>Mature Secondary Structure
MIAYLCAPHALVLQKEASHRLRPKVSRPRTRYVIGRLHSQRAAAHPASTSPLMFRLSRYY
CEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SIASLVGISIVVVVLSWFYRQLAIETLLAHQTRSNVDLTRSYANAIWHRFDAFVSASGEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SAEDLRRRPEVASLHAATLAQMHGMNVVKVKVYNLSGTTVYSSEAGQIGEDKHDNPGFLS
CHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCCCCCCCCCCCCCCCEEE
ARAGKPASEIVFRDQFYAFEEVIADRNLIATYLPIHEHGNGPVKAVFEVYTDVTPLVAKM
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHCHHHHHHHH
EATQTKIITGVVLALALLYLFLFLIVRRADQIITRQDRERQDNEQRIRHQAFHDSLTGLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
NRNSFLEHISEAIDRSKRSGNPGALLFLDLDRFKLVNDSLGHDAGDQLLRITASRIQKCL
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RETDMAFRMSGDEFVVILESVDKGEHAALAAQRVMQEMAVPMSLSGCEVIVNVSIGITTF
HHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEE
AGDSADVQALLKEADSAMYRAKQVGQNHYEFHTPDMNSAAHERLSMETDLQRALQNQEFV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LHYQPKIDTATKAIVSVEALLRWNHPTRGLVLPNTFIPLLEDTGLINPVGEWVLLQAACQ
EEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCCCCHHHHHHHHHHHH
AQAWIDAGLEPIRMSVNISAKQFRSHILVETVRRTLGASQLESRYLELELTESMFIENAE
HHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHEEEEEHHHHHHHHHH
RSIQIMQELKCLGVSLSIDDFGSGYSSLAYLKQFPVDYLKIDRSFVTDLVSNKKDAAIAV
HHHHHHHHHHHHCCEEEHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHH
AIAALAHSLDLKLVAEGVEDQAQVEFLEKQGCHELQGYLFGRPVSAEELEQVLRQADRGQ
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCH
EARRPVDTAA
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]