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The map label for this gene is ftsK2 [H]

Identifier: 74317020

GI number: 74317020

Start: 1069210

End: 1071483

Strand: Direct

Name: ftsK2 [H]

Synonym: Tbd_1002

Alternate gene names: 74317020

Gene position: 1069210-1071483 (Clockwise)

Preceding gene: 74317015

Following gene: 74317021

Centisome position: 36.75

GC content: 67.99

Gene sequence:

>2274_bases
ATGGCGCGACCCGCTCCCCGTTCGTCCCCTTCGCTGCCGCCACGCATGCAACGCCTGGTGCGCGAGGCGCGTGCCTTGCT
CGTAGGCTTCGTGGCGCTGCTGCTCGCGAGCATTCTGCTGACCCACGACGCGGCCGACCCCGGCTTCAGCACGACCGGCA
ACGGCGGCCCGCTGCAAAATCTCGGCGGCAGCGCCGGCGCCTGGCTGTCCGATCTGCTGCTCATGCTGTTCGGCGCATCG
GCCTGGTGGCTCGTTGCGCTGGCGGCCGCCTACGTGTTCCATACCTTCCGTCACCTCGATGAGGCGCCGATCGCCGGCGC
GCGCCAGCGCTGGCTGCGTCTCGGTGGCTTCGCGCTGCTGTTGCTCGCGAGCACGGGCGTCGAGTGGTTGCGCGCCTGGC
ATTGGGCGCTTGCGCTTCCCGACGCAGCCGGCGGGGTTCTCGGCACCGGCGTCGGCGCTGCGGCCGCCGCCGTGCTCGGG
TTCACGGGCGGCTCGCTGCTTCTGCTGCTCCTGATGGCGGTCGGGTTTAGCCTCTTCACGGGCGTGTCCTGGCTCACCAT
GGCCGAACGGACCGGCGAATGGCTCGAGCGCGCGTACTGGAAGACGATCGACAGCTGGCAGGCCCGGCGCGACCGCAAGC
TCGGCGAAGTCGCGCAGCAGAAGCGCCAGGCCAAGGTTTCGGTCGTCAAGAAAAAGCTCGAGGAGGCGCCGCCGGTGCGC
ATCGAGCCGGTCGTGCGAGAAGTGCCGCAGTCGGAGCGCGCGGTGACCGAGAGGCAGGCGCCGCTCTTCTCCGATCTACC
GGATTCACCGCTGCCGCCGCTGCACCTGCTCGACCCGGCCGACGAGGCGGTCGAGACCGCGAGCCCGGAAGCGCTCGAGT
TCACCTCGCTGATGATCGAGCGCAAGCTGGCCGAGTTCGGCGTCGAGGTCAAGGTGGTGTCGGCGTCGCCCGGCCCGGTC
ATCACGCGCTACGAAATCGAGCCCGCCACAGGCGTGAAGGGCAGCCAGATCGTCAACCTGGCGAAGGACCTCGCGCGCAC
GCTCTCGGTGATCAGCATTCGCGTCGTCGAGGCGATTCCGGGCAAGCACACGATGGGACTCGAGATTCCGAACCCGAAGC
GGCAGATCGTTCGCCTCTCCGAGATTCTCGGCTCCAAGGCCTACCACGACAGCGCGAGCGCGCTGACCGTCACGCTGGGC
AAGGACATCGCCGGCAACCCGGTCGTCGCCGATCTCGGCAAGATGCCGCACCTGCTCGTCGCCGGCACGACCGGCTCGGG
CAAGTCGGTCGGCGTCAACGCGATGATCCTGTCGCTCGTCTACAAATCCGACCCGAGCGCGGTGCGCATGATCATGGTCG
ACCCCAAGATGCTCGAGCTGTCGATCTACGAGGGCATTCCGCATCTGCTCGCGCCGGTCGTCACCGACATGAAGCAGGCC
GCGAGCGCGCTCAACTGGTGCGTCGCCGAGATGGAGCGGCGCTACAAATTGATGAGCGCGGTCGGCGTGCGCAACCTCGC
GGGCTACAACCAGAAGGTGCGCGACGCGAAGAAGGCCGGTACGCCGCTGACCCATCCGTTCAGCCTGACGCCCGACGACC
CCGAGCCGCTGGAGACCATGCCGATGATCGTCGTCATGATCGACGAGCTCGCCGACCTCATGATGGTCGTCGGCAAGAAG
GTCGAGGAACTGATCGCGCGGCTCGCGCAGAAGGCGCGCGCGGCCGGCATCCACCTGATCCTCGCCACGCAGCGGCCCAG
CGTCGACGTCATCACCGGCCTCATCAAGGCCAACATCCCGACGCGCATCGCCTTCCAGGTGTCGTCCAAGATCGACTCGC
GCACGATTCTCGACCAGATGGGCGCAGAGGCGCTGCTGGGGCAGGGCGACATGCTCTACCTGCCGCCCGGCACCGGGCTG
CCGCAGCGCGTCCACGGCGCCTTCGTCTCGGACAATGAGGTGCACCGCGTCGTCGACTATCTCAAAGCGCTGGGCGAGCC
CGAATACATCGAAGGCGTGCTCGAGTCGCCCGAGGAGGGCGGTGAAGGCAGCGAGTTCGGCGAGCCCGGCGCCGAGGCTG
ATCCGCTCTACGACCAAGCCGTCGCCTATGTGCTCAAGACGCGTCGTGCGTCGATTTCGTCAGTGCAGCGCCAATTGCGC
ATCGGCTACAACCGCGCCGCCCGCATGATCGAGGATATGGAACGCGCCGGGCTCGTCTCGTCGATGCAGTCGAACGGCAA
CCGGGAGGTGCTGGCGCCCGGAGGTGAGGCATGA

Upstream 100 bases:

>100_bases
GGTGGGATGGGGCAGTGGCTTATTCTAACCAAAACCGGGAGCGGCATTTCCATGCTGCCGCCCCGGTATAATCCGCCACA
CTTTCGCTCGTCACCTTTCC

Downstream 100 bases:

>100_bases
AATTCTACGCACTGATACCCGCTGCCGGCTCGGGCTCACGCATGGGCGGCGCGATCGAAAAGCAGTATATGGATGTCAAC
TCGGTGCCGATGATCGCGCA

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 756

Protein sequence:

>757_residues
MARPAPRSSPSLPPRMQRLVREARALLVGFVALLLASILLTHDAADPGFSTTGNGGPLQNLGGSAGAWLSDLLLMLFGAS
AWWLVALAAAYVFHTFRHLDEAPIAGARQRWLRLGGFALLLLASTGVEWLRAWHWALALPDAAGGVLGTGVGAAAAAVLG
FTGGSLLLLLLMAVGFSLFTGVSWLTMAERTGEWLERAYWKTIDSWQARRDRKLGEVAQQKRQAKVSVVKKKLEEAPPVR
IEPVVREVPQSERAVTERQAPLFSDLPDSPLPPLHLLDPADEAVETASPEALEFTSLMIERKLAEFGVEVKVVSASPGPV
ITRYEIEPATGVKGSQIVNLAKDLARTLSVISIRVVEAIPGKHTMGLEIPNPKRQIVRLSEILGSKAYHDSASALTVTLG
KDIAGNPVVADLGKMPHLLVAGTTGSGKSVGVNAMILSLVYKSDPSAVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKQA
ASALNWCVAEMERRYKLMSAVGVRNLAGYNQKVRDAKKAGTPLTHPFSLTPDDPEPLETMPMIVVMIDELADLMMVVGKK
VEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGTGL
PQRVHGAFVSDNEVHRVVDYLKALGEPEYIEGVLESPEEGGEGSEFGEPGAEADPLYDQAVAYVLKTRRASISSVQRQLR
IGYNRAARMIEDMERAGLVSSMQSNGNREVLAPGGEA

Sequences:

>Translated_757_residues
MARPAPRSSPSLPPRMQRLVREARALLVGFVALLLASILLTHDAADPGFSTTGNGGPLQNLGGSAGAWLSDLLLMLFGAS
AWWLVALAAAYVFHTFRHLDEAPIAGARQRWLRLGGFALLLLASTGVEWLRAWHWALALPDAAGGVLGTGVGAAAAAVLG
FTGGSLLLLLLMAVGFSLFTGVSWLTMAERTGEWLERAYWKTIDSWQARRDRKLGEVAQQKRQAKVSVVKKKLEEAPPVR
IEPVVREVPQSERAVTERQAPLFSDLPDSPLPPLHLLDPADEAVETASPEALEFTSLMIERKLAEFGVEVKVVSASPGPV
ITRYEIEPATGVKGSQIVNLAKDLARTLSVISIRVVEAIPGKHTMGLEIPNPKRQIVRLSEILGSKAYHDSASALTVTLG
KDIAGNPVVADLGKMPHLLVAGTTGSGKSVGVNAMILSLVYKSDPSAVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKQA
ASALNWCVAEMERRYKLMSAVGVRNLAGYNQKVRDAKKAGTPLTHPFSLTPDDPEPLETMPMIVVMIDELADLMMVVGKK
VEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGTGL
PQRVHGAFVSDNEVHRVVDYLKALGEPEYIEGVLESPEEGGEGSEFGEPGAEADPLYDQAVAYVLKTRRASISSVQRQLR
IGYNRAARMIEDMERAGLVSSMQSNGNREVLAPGGEA
>Mature_756_residues
ARPAPRSSPSLPPRMQRLVREARALLVGFVALLLASILLTHDAADPGFSTTGNGGPLQNLGGSAGAWLSDLLLMLFGASA
WWLVALAAAYVFHTFRHLDEAPIAGARQRWLRLGGFALLLLASTGVEWLRAWHWALALPDAAGGVLGTGVGAAAAAVLGF
TGGSLLLLLLMAVGFSLFTGVSWLTMAERTGEWLERAYWKTIDSWQARRDRKLGEVAQQKRQAKVSVVKKKLEEAPPVRI
EPVVREVPQSERAVTERQAPLFSDLPDSPLPPLHLLDPADEAVETASPEALEFTSLMIERKLAEFGVEVKVVSASPGPVI
TRYEIEPATGVKGSQIVNLAKDLARTLSVISIRVVEAIPGKHTMGLEIPNPKRQIVRLSEILGSKAYHDSASALTVTLGK
DIAGNPVVADLGKMPHLLVAGTTGSGKSVGVNAMILSLVYKSDPSAVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKQAA
SALNWCVAEMERRYKLMSAVGVRNLAGYNQKVRDAKKAGTPLTHPFSLTPDDPEPLETMPMIVVMIDELADLMMVVGKKV
EELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGTGLP
QRVHGAFVSDNEVHRVVDYLKALGEPEYIEGVLESPEEGGEGSEFGEPGAEADPLYDQAVAYVLKTRRASISSVQRQLRI
GYNRAARMIEDMERAGLVSSMQSNGNREVLAPGGEA

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=65.1115618661258, Blast_Score=616, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 81484; Mature: 81352

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPAPRSSPSLPPRMQRLVREARALLVGFVALLLASILLTHDAADPGFSTTGNGGPLQN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
LGGSAGAWLSDLLLMLFGASAWWLVALAAAYVFHTFRHLDEAPIAGARQRWLRLGGFALL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLASTGVEWLRAWHWALALPDAAGGVLGTGVGAAAAAVLGFTGGSLLLLLLMAVGFSLFT
HHHHCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GVSWLTMAERTGEWLERAYWKTIDSWQARRDRKLGEVAQQKRQAKVSVVKKKLEEAPPVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IEPVVREVPQSERAVTERQAPLFSDLPDSPLPPLHLLDPADEAVETASPEALEFTSLMIE
ECHHHHHCCCHHHHHHHHCCCCHHCCCCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHH
RKLAEFGVEVKVVSASPGPVITRYEIEPATGVKGSQIVNLAKDLARTLSVISIRVVEAIP
HHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKHTMGLEIPNPKRQIVRLSEILGSKAYHDSASALTVTLGKDIAGNPVVADLGKMPHLLV
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCCEEEE
AGTTGSGKSVGVNAMILSLVYKSDPSAVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKQA
EECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHH
ASALNWCVAEMERRYKLMSAVGVRNLAGYNQKVRDAKKAGTPLTHPFSLTPDDPEPLETM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
PMIVVMIDELADLMMVVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCC
TRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGTGLPQRVHGAFVSDNEVHRVVDY
CEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCHHHCCCCCCCCHHHHHHHH
LKALGEPEYIEGVLESPEEGGEGSEFGEPGAEADPLYDQAVAYVLKTRRASISSVQRQLR
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGYNRAARMIEDMERAGLVSSMQSNGNREVLAPGGEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure 
ARPAPRSSPSLPPRMQRLVREARALLVGFVALLLASILLTHDAADPGFSTTGNGGPLQN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
LGGSAGAWLSDLLLMLFGASAWWLVALAAAYVFHTFRHLDEAPIAGARQRWLRLGGFALL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLASTGVEWLRAWHWALALPDAAGGVLGTGVGAAAAAVLGFTGGSLLLLLLMAVGFSLFT
HHHHCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GVSWLTMAERTGEWLERAYWKTIDSWQARRDRKLGEVAQQKRQAKVSVVKKKLEEAPPVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IEPVVREVPQSERAVTERQAPLFSDLPDSPLPPLHLLDPADEAVETASPEALEFTSLMIE
ECHHHHHCCCHHHHHHHHCCCCHHCCCCCCCCCCEECCCCHHHHHCCCCCHHHHHHHHHH
RKLAEFGVEVKVVSASPGPVITRYEIEPATGVKGSQIVNLAKDLARTLSVISIRVVEAIP
HHHHHCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKHTMGLEIPNPKRQIVRLSEILGSKAYHDSASALTVTLGKDIAGNPVVADLGKMPHLLV
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCCEEEE
AGTTGSGKSVGVNAMILSLVYKSDPSAVRMIMVDPKMLELSIYEGIPHLLAPVVTDMKQA
EECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHH
ASALNWCVAEMERRYKLMSAVGVRNLAGYNQKVRDAKKAGTPLTHPFSLTPDDPEPLETM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
PMIVVMIDELADLMMVVGKKVEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCC
TRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGTGLPQRVHGAFVSDNEVHRVVDY
CEEEEEEHHCCHHHHHHHHHCHHHHHCCCCEEEECCCCCCCHHHCCCCCCCCHHHHHHHH
LKALGEPEYIEGVLESPEEGGEGSEFGEPGAEADPLYDQAVAYVLKTRRASISSVQRQLR
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IGYNRAARMIEDMERAGLVSSMQSNGNREVLAPGGEA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]