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The map label for this gene is ubiB [C]

Identifier: 74317012

GI number: 74317012

Start: 1059339

End: 1061018

Strand: Direct

Name: ubiB [C]

Synonym: Tbd_0994

Alternate gene names: 74317012

Gene position: 1059339-1061018 (Clockwise)

Preceding gene: 74317011

Following gene: 74317015

Centisome position: 36.41

GC content: 65.3

Gene sequence:

>1680_bases
ATGCTCTGGGAAACCCTCTCGGTCGTTCGCGACCTGCCGCGCCTGCACGAAATTGCCTCGGTGATGATTCGCTACGGCTG
GGGCGATCTGGTACGCGTGCTCGGCATCAACGGCGCGCTCGAACGCGCCGGCCGCGTGCTGCACTGGCACAGCACGAGCG
AGATCAGTCAACTCGACGCGCCGGTCCGCGTACGCCGCGCGCTCGAGGAACTCGGGCCGACTTTCGTCAAGCTCGGACAG
GTGCTGGCGACGCGCGTCGACATGTTCCCGCCGAACTGGATCGCGGAATTCGAGAAACTGCACAGCCAGGTGCCCGCGCA
GAGTTACGAGGTGATGTACCCCGAACTGGTCGCCGCGATCGGCGGCGAGCCCGGCGAGGTGTTCGCCGCCTTCGACCCGG
TGCCACTCGCCGCGGCGTCGATCGCCCAGGTGTACCGCGCGACGCTCAAGGACGGCACGCCGGTCGTCGTGAAAATGCGC
CGCCCGGGCATCGAGACGGTGATCCGCGCCGATCTGCGCATCCTCGACCATGCGGCGCGGCTGCTCGAGAGCGAGGTCGC
CGACGCACGCCGCTACGACCCGGTGCAGATCGTGTCGCAGTTCAGGCGCTCGCTCAGCCGCGAATTGGATCTCGCCAAGG
AGGCGCGCAACATCGACCAGTTCGCGCGTCATTTCGCGACCGACCCGCTGGTCAAGATTCCGAAGGTCTACTGGGAATTC
ACCAACGACCAGGTCAACGTCCAGGAGGAGATCGTCGGCCTTGCCGGCGTTTCCCCCGACAAGCTGCGCGCGGCGGGTCT
CGACCCCAAGCTCCTCGCCGCGCGCGGCGCCAACGCCGTGCTGTCGATGGTATTGCTGCACGGCTATTTCCACGCCGACC
CGCACCCCGGCAACGTCCTCTTCCTGCCCGGCAACCGGATCGGCATGATCGATTTCGGCATGGTCGGGATGCTGACCGAG
CCGCGCCGCAACCAGATCGTCGACCTGCTGCATGCGCTGACCCGACGCGACGAACAGGCGCTGCTGCAGGTGCTGCTCGA
CTGGAGCGGGGACTCGGTTCCCGACGACGAGCGTCTCGCCTACGACGTCGCCGAGCTCATGCAAAGCTACGACGACCTGC
AGCTCAAGGACGTCAAGATCGGCGCCCTGCTGAATGACATCACCGCCTTGATGCGCGACAACAACCTCGTGCTGCCGGCC
GACCTGACCTTGCTCTTCAAGACCCTGATCACACTCGAGGGCCTCGGACAGCAGCTCGATCCCGAGTTCCACATGATCGA
CAACGTGACGCCGTTCGTCGAAAGCGTGATCAAGGAGCGCTATACGCCGCAGGCCCTGTTCGTGCGCGGACGCAAGAGCG
TGCGCGAGGCGCTCGAAGTGGCGGCCGATTTGCCGCGCGATCTGCGGCACCTGTTGCGTGACATGCGGCGCGGCCGCGTC
AAGGTCGATTTCGACCTCAAGCGCCTCGACCATTTCGGTCACCAACTCGACAGTGCCGCGAGCAGGCTGACGATGGGCAT
TCTGACCGCTTCGCTCGTCGTCGGGTCGAGCATCATCATGACGGTCAAGGGTGGTCCGGAGCTGTTCGGGCTGCCGTTCT
TCGGGCTGGTCGGGTTTCTGATCGCGTTTTTCAACAGCGTGTGGATCGTGCTGTCGATCTGGCGTTCAGGGAAGCACTGA

Upstream 100 bases:

>100_bases
CTTGCGCCCCTGATACGTACTAAGCCCAAGCGGGGGACACGCCCGCACCGCCTGCCGCTACACTCTCGGCAACGGCATTA
CTGACGCCACAAAACCAACG

Downstream 100 bases:

>100_bases
CGCGACCTCGGCGGATTCGGCGACGCGCTCCTGCGCGGCGCCCGCGTTCGCCAGTTTGTCGAGCGGCAGGGGCCGGCTCA
GGAGATAGCCCTGCACGTGC

Product: 2-octaprenylphenol hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLWETLSVVRDLPRLHEIASVMIRYGWGDLVRVLGINGALERAGRVLHWHSTSEISQLDAPVRVRRALEELGPTFVKLGQ
VLATRVDMFPPNWIAEFEKLHSQVPAQSYEVMYPELVAAIGGEPGEVFAAFDPVPLAAASIAQVYRATLKDGTPVVVKMR
RPGIETVIRADLRILDHAARLLESEVADARRYDPVQIVSQFRRSLSRELDLAKEARNIDQFARHFATDPLVKIPKVYWEF
TNDQVNVQEEIVGLAGVSPDKLRAAGLDPKLLAARGANAVLSMVLLHGYFHADPHPGNVLFLPGNRIGMIDFGMVGMLTE
PRRNQIVDLLHALTRRDEQALLQVLLDWSGDSVPDDERLAYDVAELMQSYDDLQLKDVKIGALLNDITALMRDNNLVLPA
DLTLLFKTLITLEGLGQQLDPEFHMIDNVTPFVESVIKERYTPQALFVRGRKSVREALEVAADLPRDLRHLLRDMRRGRV
KVDFDLKRLDHFGHQLDSAASRLTMGILTASLVVGSSIIMTVKGGPELFGLPFFGLVGFLIAFFNSVWIVLSIWRSGKH

Sequences:

>Translated_559_residues
MLWETLSVVRDLPRLHEIASVMIRYGWGDLVRVLGINGALERAGRVLHWHSTSEISQLDAPVRVRRALEELGPTFVKLGQ
VLATRVDMFPPNWIAEFEKLHSQVPAQSYEVMYPELVAAIGGEPGEVFAAFDPVPLAAASIAQVYRATLKDGTPVVVKMR
RPGIETVIRADLRILDHAARLLESEVADARRYDPVQIVSQFRRSLSRELDLAKEARNIDQFARHFATDPLVKIPKVYWEF
TNDQVNVQEEIVGLAGVSPDKLRAAGLDPKLLAARGANAVLSMVLLHGYFHADPHPGNVLFLPGNRIGMIDFGMVGMLTE
PRRNQIVDLLHALTRRDEQALLQVLLDWSGDSVPDDERLAYDVAELMQSYDDLQLKDVKIGALLNDITALMRDNNLVLPA
DLTLLFKTLITLEGLGQQLDPEFHMIDNVTPFVESVIKERYTPQALFVRGRKSVREALEVAADLPRDLRHLLRDMRRGRV
KVDFDLKRLDHFGHQLDSAASRLTMGILTASLVVGSSIIMTVKGGPELFGLPFFGLVGFLIAFFNSVWIVLSIWRSGKH
>Mature_559_residues
MLWETLSVVRDLPRLHEIASVMIRYGWGDLVRVLGINGALERAGRVLHWHSTSEISQLDAPVRVRRALEELGPTFVKLGQ
VLATRVDMFPPNWIAEFEKLHSQVPAQSYEVMYPELVAAIGGEPGEVFAAFDPVPLAAASIAQVYRATLKDGTPVVVKMR
RPGIETVIRADLRILDHAARLLESEVADARRYDPVQIVSQFRRSLSRELDLAKEARNIDQFARHFATDPLVKIPKVYWEF
TNDQVNVQEEIVGLAGVSPDKLRAAGLDPKLLAARGANAVLSMVLLHGYFHADPHPGNVLFLPGNRIGMIDFGMVGMLTE
PRRNQIVDLLHALTRRDEQALLQVLLDWSGDSVPDDERLAYDVAELMQSYDDLQLKDVKIGALLNDITALMRDNNLVLPA
DLTLLFKTLITLEGLGQQLDPEFHMIDNVTPFVESVIKERYTPQALFVRGRKSVREALEVAADLPRDLRHLLRDMRRGRV
KVDFDLKRLDHFGHQLDSAASRLTMGILTASLVVGSSIIMTVKGGPELFGLPFFGLVGFLIAFFNSVWIVLSIWRSGKH

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=305, Percent_Identity=29.8360655737705, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=29.1512915129151, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI217035081, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI32261307, Length=338, Percent_Identity=23.9644970414201, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27363457, Length=279, Percent_Identity=25.4480286738351, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI217416386, Length=225, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI34147522, Length=343, Percent_Identity=23.0320699708455, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367309, Length=540, Percent_Identity=31.8518518518519, Blast_Score=229, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17559152, Length=280, Percent_Identity=29.2857142857143, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17555620, Length=480, Percent_Identity=23.75, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32565180, Length=252, Percent_Identity=26.5873015873016, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325148, Length=441, Percent_Identity=26.984126984127, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321319, Length=303, Percent_Identity=26.0726072607261, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323282, Length=248, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI22024280, Length=273, Percent_Identity=28.9377289377289, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24662575, Length=281, Percent_Identity=27.0462633451957, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859849, Length=273, Percent_Identity=27.1062271062271, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62576; Mature: 62576

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWETLSVVRDLPRLHEIASVMIRYGWGDLVRVLGINGALERAGRVLHWHSTSEISQLDA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHCCC
PVRVRRALEELGPTFVKLGQVLATRVDMFPPNWIAEFEKLHSQVPAQSYEVMYPELVAAI
CHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GGEPGEVFAAFDPVPLAAASIAQVYRATLKDGTPVVVKMRRPGIETVIRADLRILDHAAR
CCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
LLESEVADARRYDPVQIVSQFRRSLSRELDLAKEARNIDQFARHFATDPLVKIPKVYWEF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEE
TNDQVNVQEEIVGLAGVSPDKLRAAGLDPKLLAARGANAVLSMVLLHGYFHADPHPGNVL
CCCCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEE
FLPGNRIGMIDFGMVGMLTEPRRNQIVDLLHALTRRDEQALLQVLLDWSGDSVPDDERLA
EECCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHH
YDVAELMQSYDDLQLKDVKIGALLNDITALMRDNNLVLPADLTLLFKTLITLEGLGQQLD
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCC
PEFHMIDNVTPFVESVIKERYTPQALFVRGRKSVREALEVAADLPRDLRHLLRDMRRGRV
CCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCE
KVDFDLKRLDHFGHQLDSAASRLTMGILTASLVVGSSIIMTVKGGPELFGLPFFGLVGFL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCHHHHHHHHH
IAFFNSVWIVLSIWRSGKH
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLWETLSVVRDLPRLHEIASVMIRYGWGDLVRVLGINGALERAGRVLHWHSTSEISQLDA
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHCCCEEEECCCHHHHHCCC
PVRVRRALEELGPTFVKLGQVLATRVDMFPPNWIAEFEKLHSQVPAQSYEVMYPELVAAI
CHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GGEPGEVFAAFDPVPLAAASIAQVYRATLKDGTPVVVKMRRPGIETVIRADLRILDHAAR
CCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
LLESEVADARRYDPVQIVSQFRRSLSRELDLAKEARNIDQFARHFATDPLVKIPKVYWEF
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEE
TNDQVNVQEEIVGLAGVSPDKLRAAGLDPKLLAARGANAVLSMVLLHGYFHADPHPGNVL
CCCCCCHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEE
FLPGNRIGMIDFGMVGMLTEPRRNQIVDLLHALTRRDEQALLQVLLDWSGDSVPDDERLA
EECCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHH
YDVAELMQSYDDLQLKDVKIGALLNDITALMRDNNLVLPADLTLLFKTLITLEGLGQQLD
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCCCCC
PEFHMIDNVTPFVESVIKERYTPQALFVRGRKSVREALEVAADLPRDLRHLLRDMRRGRV
CCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCE
KVDFDLKRLDHFGHQLDSAASRLTMGILTASLVVGSSIIMTVKGGPELFGLPFFGLVGFL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCHHHHHHHHH
IAFFNSVWIVLSIWRSGKH
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA