Click here to switch to the map view.

The map label for this gene is zraR [H]

Identifier: 74316922

GI number: 74316922

Start: 960127

End: 961491

Strand: Direct

Name: zraR [H]

Synonym: Tbd_0904

Alternate gene names: 74316922

Gene position: 960127-961491 (Clockwise)

Preceding gene: 74316921

Following gene: 74316923

Centisome position: 33.0

GC content: 67.47

Gene sequence:

>1365_bases
ATGCGCATTTTGTTGGTCGACGATCAGAAAAGCCTGCGGCGCAGCCTGTCGCTAATGCTGCAGGGCGCGGGTTTCGAAAC
CGGCGAAGCCGAAAGCGGCGAGGAGGCGCTGTCGTGCCTGGGCGCCGAGCGTTTCGATCTGGTGATCACCGACCTGCGCA
TGGAGGGCATGTCGGGCGTCGACCTGCTGCGCGAAATCAAGCGGCTGAATCCGCTGCTGCCGGTGATCCTGATCACCGCC
TACGGCAGCATCGACTCGGCGGTCGACGCGATGCGCCTGGGCGCCTTCGACTATCTGACCAAGCCCTTCCGCGAGCAGGA
CATCCTGGAAAAGATCCGCGCGAGCCAGTCGGCGCCGCCCGGTTTCGCCCTTGCGGCCGAAGCCTCGCGCGACGCCGAAG
ACATCGTCGCCGACACGCCGCAGATGCGGGCCACGCTGATCAAGGCCGAGCGCATCGCGCGGACCGACATCAGCGTCCTC
ATCACCGGTGAAACGGGCACCGGCAAGACCCGGGTCGCGCGCTTCATCCACGAGAACAGCGCGCGCCGCGAGGCGCCTTT
CGTCAGCATCAACTGCGCGAGCCTGCCCGAGAACCTGCTCGAGAGCGAACTCTTCGGCCACGTGAAGGGCGCCTTCACCG
GGGCCACCGAATCGCGCGCCGGCCTTTTCGAGGAGGCCGACGGCGGCACGCTGTTCCTCGACGAGGTGGACACGCTGTCG
CCGGCGATGCAGGCCAAGCTGCTGTCGGTGCTGCAGGAAAAAGTCATCCGCCGCGTCGGCTCGAACAAGGGCAAGAAGGT
CGACATCCGCATCATGTCGGCGAGCAACCAGGACCTCGCCCTGCTCATCGACAAGGGCCATTTCCGCTCCGACCTGTACT
TCCGCCTCAACGGCATCCGCCTGCATCTGCCGCCGCTGCGCGAGCGCGGGCAGGACCTGCACAACCTGCTGCAGCGCTTT
CTGGCCGTCTATGGCCGCAAGTACGGGCGCGGCCGGCTACGGCTGTCGCCGCGCGCCGAGGCCTATGTGCTGGGCTATGC
GTATCCGGGAAACATCCGCCAGCTCGAAAGCTTCGTCGAGCAGATGGCGGTGTTCGCCGACGACGCCGGCTACATCGACG
TCGACGCGCTGCCCGAGGACCTGTTGCAGCAGGCGCCCGCGGCGATGCCGCGGCACGAACCGGCCGAACTCGGCGAGGGC
GGCGGCAGCATCGCCGACTCCCAGCGGCGGATGATCGAAGCGACGCTGCAGCGTGCGTCCAACATCGGCGAGGCGGCGCG
CGTCCTCGGCATCGGCCGCACGACGCTGTGGCGCAAGATGCGCGAGTACAACCTGCATTTCCCGCCGCACGGGCGCAATC
GCTGA

Upstream 100 bases:

>100_bases
GATGCATCCGGGTGCGTAGCCGGGTGGGGGAGGGGACCCGATTCTTCCTGCGGGTGCCCGTACGGGTCGGGGAAAGCTTT
TTCGGACGCGAGGTCGCCTG

Downstream 100 bases:

>100_bases
CGTTTCCGTCCCGTACCGCTCTGGTACGGGGCTTGCTTTTCAGAGCGGTGAGGGCCTTGTCCCACCGTTTTGAAACAGCA
GGAGACGCAAGCATGTCCGT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRILLVDDQKSLRRSLSLMLQGAGFETGEAESGEEALSCLGAERFDLVITDLRMEGMSGVDLLREIKRLNPLLPVILITA
YGSIDSAVDAMRLGAFDYLTKPFREQDILEKIRASQSAPPGFALAAEASRDAEDIVADTPQMRATLIKAERIARTDISVL
ITGETGTGKTRVARFIHENSARREAPFVSINCASLPENLLESELFGHVKGAFTGATESRAGLFEEADGGTLFLDEVDTLS
PAMQAKLLSVLQEKVIRRVGSNKGKKVDIRIMSASNQDLALLIDKGHFRSDLYFRLNGIRLHLPPLRERGQDLHNLLQRF
LAVYGRKYGRGRLRLSPRAEAYVLGYAYPGNIRQLESFVEQMAVFADDAGYIDVDALPEDLLQQAPAAMPRHEPAELGEG
GGSIADSQRRMIEATLQRASNIGEAARVLGIGRTTLWRKMREYNLHFPPHGRNR

Sequences:

>Translated_454_residues
MRILLVDDQKSLRRSLSLMLQGAGFETGEAESGEEALSCLGAERFDLVITDLRMEGMSGVDLLREIKRLNPLLPVILITA
YGSIDSAVDAMRLGAFDYLTKPFREQDILEKIRASQSAPPGFALAAEASRDAEDIVADTPQMRATLIKAERIARTDISVL
ITGETGTGKTRVARFIHENSARREAPFVSINCASLPENLLESELFGHVKGAFTGATESRAGLFEEADGGTLFLDEVDTLS
PAMQAKLLSVLQEKVIRRVGSNKGKKVDIRIMSASNQDLALLIDKGHFRSDLYFRLNGIRLHLPPLRERGQDLHNLLQRF
LAVYGRKYGRGRLRLSPRAEAYVLGYAYPGNIRQLESFVEQMAVFADDAGYIDVDALPEDLLQQAPAAMPRHEPAELGEG
GGSIADSQRRMIEATLQRASNIGEAARVLGIGRTTLWRKMREYNLHFPPHGRNR
>Mature_454_residues
MRILLVDDQKSLRRSLSLMLQGAGFETGEAESGEEALSCLGAERFDLVITDLRMEGMSGVDLLREIKRLNPLLPVILITA
YGSIDSAVDAMRLGAFDYLTKPFREQDILEKIRASQSAPPGFALAAEASRDAEDIVADTPQMRATLIKAERIARTDISVL
ITGETGTGKTRVARFIHENSARREAPFVSINCASLPENLLESELFGHVKGAFTGATESRAGLFEEADGGTLFLDEVDTLS
PAMQAKLLSVLQEKVIRRVGSNKGKKVDIRIMSASNQDLALLIDKGHFRSDLYFRLNGIRLHLPPLRERGQDLHNLLQRF
LAVYGRKYGRGRLRLSPRAEAYVLGYAYPGNIRQLESFVEQMAVFADDAGYIDVDALPEDLLQQAPAAMPRHEPAELGEG
GGSIADSQRRMIEATLQRASNIGEAARVLGIGRTTLWRKMREYNLHFPPHGRNR

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=42.3076923076923, Blast_Score=317, Evalue=7e-88,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=39.8720682302772, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=40.6181015452539, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1788905, Length=445, Percent_Identity=40, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=40.3726708074534, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082152, Length=252, Percent_Identity=47.2222222222222, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=45.0643776824034, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787583, Length=330, Percent_Identity=35.7575757575758, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.2597402597403, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786524, Length=321, Percent_Identity=39.8753894080997, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=36.8589743589744, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87081858, Length=308, Percent_Identity=31.1688311688312, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=36.1867704280156, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=33.0434782608696, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786784, Length=145, Percent_Identity=30.3448275862069, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787375, Length=123, Percent_Identity=32.520325203252, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=32.7433628318584, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789402, Length=103, Percent_Identity=36.8932038834951, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=115, Percent_Identity=34.7826086956522, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=32.4561403508772, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787487, Length=151, Percent_Identity=31.1258278145695, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1790552, Length=114, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1786911, Length=101, Percent_Identity=32.6732673267327, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50214; Mature: 50214

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVDDQKSLRRSLSLMLQGAGFETGEAESGEEALSCLGAERFDLVITDLRMEGMSGV
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEHHHCCCCHH
DLLREIKRLNPLLPVILITAYGSIDSAVDAMRLGAFDYLTKPFREQDILEKIRASQSAPP
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCCCCCC
GFALAAEASRDAEDIVADTPQMRATLIKAERIARTDISVLITGETGTGKTRVARFIHENS
CEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
ARREAPFVSINCASLPENLLESELFGHVKGAFTGATESRAGLFEEADGGTLFLDEVDTLS
CCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECCHHHCC
PAMQAKLLSVLQEKVIRRVGSNKGKKVDIRIMSASNQDLALLIDKGHFRSDLYFRLNGIR
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECEE
LHLPPLRERGQDLHNLLQRFLAVYGRKYGRGRLRLSPRAEAYVLGYAYPGNIRQLESFVE
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHH
QMAVFADDAGYIDVDALPEDLLQQAPAAMPRHEPAELGEGGGSIADSQRRMIEATLQRAS
HHHHHCCCCCEEEHHCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
NIGEAARVLGIGRTTLWRKMREYNLHFPPHGRNR
CHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRILLVDDQKSLRRSLSLMLQGAGFETGEAESGEEALSCLGAERFDLVITDLRMEGMSGV
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHEEEEEEHHHCCCCHH
DLLREIKRLNPLLPVILITAYGSIDSAVDAMRLGAFDYLTKPFREQDILEKIRASQSAPP
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCCCCCC
GFALAAEASRDAEDIVADTPQMRATLIKAERIARTDISVLITGETGTGKTRVARFIHENS
CEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCC
ARREAPFVSINCASLPENLLESELFGHVKGAFTGATESRAGLFEEADGGTLFLDEVDTLS
CCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECCHHHCC
PAMQAKLLSVLQEKVIRRVGSNKGKKVDIRIMSASNQDLALLIDKGHFRSDLYFRLNGIR
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECEE
LHLPPLRERGQDLHNLLQRFLAVYGRKYGRGRLRLSPRAEAYVLGYAYPGNIRQLESFVE
EECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHH
QMAVFADDAGYIDVDALPEDLLQQAPAAMPRHEPAELGEGGGSIADSQRRMIEATLQRAS
HHHHHCCCCCEEEHHCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHH
NIGEAARVLGIGRTTLWRKMREYNLHFPPHGRNR
CHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]