Click here to switch to the map view.

The map label for this gene is pepN [H]

Identifier: 74316917

GI number: 74316917

Start: 948937

End: 951714

Strand: Reverse

Name: pepN [H]

Synonym: Tbd_0899

Alternate gene names: 74316917

Gene position: 951714-948937 (Counterclockwise)

Preceding gene: 74316937

Following gene: 74316913

Centisome position: 32.71

GC content: 68.32

Gene sequence:

>2778_bases
ATGCGCACCGAAACCCCCGTCACGCTTTACCTGAAGGATTACGCCCCGCCCGCCTGGCGGATCGAGTCGGCCGACCTGCA
CGTCGCCATCCACGACGACCATGCCGAGGTGCGTGCGCGCCTCGACTGCGTGCGCAACACCGCGGGCGGCGACGACGCGC
TGGTTCTGAACGGCGAAGCGCTGGAACTCGTCGGCCTCAGCCTCGACGGCGCGCCGCTCGACCCCGCGCGCTACGTGTAC
GGCGACGATCTGCTGCGCATCGCGGGGCCCCTGCCCGATCGCTGCGTGCTCGAAAGCGTCGTGCGCATCCGCCCCGATCT
GAACACCCAGCTCTCGGGCCTCTACCGCTCGCAGGACGGCTATTTCACGCAATGCGAGCCCGAAGGCTTCCGCCGCATCA
CCTTCTTCCCGGACCGGCCCGACGTGATGACGAAATTCAGCTGCACGGTCGAAGCCGACCGCGCGCGGTTTCCGCATCTG
CTGTCGAACGGCAATCCCGTGGCGGCGGGGGTCTGCGACGACGACGCAGCGCGGCACTGGGCGCGCTGGGACGACCCCTA
CGCCAAGCCGTGCTACCTGTTCGCGCTCGTCGCCGCCAGGCTCGACGTGCTGGAGGACGAATACGTCACCGCCTCGGGAC
GCAAGGTCAGGCTCGCGGTCTACGTCGAGCCGGGCAAGCTCGACCAGTGCGGCCACGCGATGGCCGCGCTGAAAAAAGCC
ATGCGCTGGGACGAAGAGCGCTTCGGCCTCGAATACGACCTCGACCAGTACATGATCGTCGCCGTCGGCGACTTCAACAT
GGGGGCGATGGAGAACAAGGGCCTCAACATCTTCAATACCAAATACGTGCTCGCCCGCCCCGACACCGCGACCGACGCCG
ACTACCAGGGCATCGACCGCGTGGTGGCGCACGAGTATTTCCACAACTGGACCGGCAACCGCGTCACCTGCCGCGACTGG
TTCCAGCTGTCGTTGAAGGAAGGCCTCACGGTGTTCCGCGACCAGGAATTCGGCGCCGACACGCACTCGCGCGCGGTCAC
CCGCATCCAGGAAGTGCGCGCACTGCGCGTCGGCCAGTTCCCCGAAGACGTCGGGCCGATGGCGCACCCGATCCGGCCGG
CCTCCTACGCCGAGATCAACAACTTCTACACCGCCACCGTCTACAACAAGGGCGCGGAAGTCATCCGCATGATGCACACC
CTGCTCGGGCGCGAGGCGTTCCGCCGCGGCACGGATTTGTACTTCGCGCGCCACGACGGCCAGGCCGTCACCTGCGAGGA
TTTCGTCGCAGCGATGCAGGATGCTTCCGGGATCGACCTCGCGCAGTTCCGCCGCTGGTACGCGCGCGCCGGCACGCCGC
GCCTGAACGCATCAAGCAGCTACGACGCCACGACCCGACGCTACACGCTGACGCTCACGCAAACCCTCGCGCCGACCGCC
TACGAAAAGCGGCTGACCGAATCGGGACAGGCCATCGTCGACGGCACGCTGCACATCCCCGTCGCGCTCGGGCTGGTATT
GCCAAATGGTAATGACGCGCCGCTGAAACTCGCCGGTGAGGCCGAGGCGAGCGGCACCACGCGCGTCCTCTCGCTGACCG
AGCCCACGCAGACCTTCGTCTTCGAGGACATTCCCGCCGCCCCCGTCGCCTCGCTGCTGCGCGATTTTTCGGCGCCGGTG
CAGTTGGAGTTCGAACAGACCGACGCCGAGCTCGCGCACCTGATGGCACACGATGACGACGCCTTCAACCGCTGGGAAGC
CGGGCAGCGGCTGGCGACGCGGGTGCTGCTCGCCGGTATTGCCGCGCAGCAACGCGCAGCGTTGATGCGCCATACTCTCC
CGCATGCGGGAGAGGACGACTCGTGGCGTGGCGCCGGCAGCGACTGGATTCCCGACGCCTTCGTCGCCGCCTGCGGCCGC
GTGCTCGACGCCGGCCTCGCCGGCGACCCGGCGCTGGCTGCCGAAGCGCTCAACCTGCCCGCCGAAGCCGTGCTCGCCGA
AGCGGTGGTATCGCTTGGCCAGCCCATCGACCCCGAAGCCATCCACGCCGCGCGCGTGGCCCTGCGCCGCCACCTCGCCG
CCCGTCTGCGCGACGCCTTCGAAGCCGCTTGGGCCGCCCTCACCCCAACTGCGGCCTATGCGCCCGACGGCGCCCAGGTC
GGCCAGCGCGCCCTGCGCAACGCCTGCCTCGGCTACCTCGCCGAAAGCGACGTCGAGTATTTGCAGAGCGCGGTCGTCCC
GCGCCTCACCGCCCAGCTCGCGGCGGGCGGCAACATGACCGACGGCAACATGACCAGTCAAATGGCCGCGCTGGCCACGC
TCGCCAACCTCGACCTGCCGGAAAGGGAAGCGACGCTCGCCGATTTCTACACGCGCTGGCAAAACGAAGCCCTGGTCGTC
GACAAGTGGTTTGCCGTGCAAGCCACCTCGCGCCTGCCAGGCACCGCCGCGCGCGTGCGCGCGCTGATGCAGCATCCGGC
GTTTGACCTCAAGAACCCCAACCGCGTCTATGCCCTGATCCGCGGCTTCTGCGGCGCCAACCCGCGCCACTTCCACGCCT
TTGATGGCAGCGGCTACGCGCTGGCGGCCGACGTCATCAGCGAATTGCAGGCCATCAACCCCCAGGTCGCGTCACGCATC
GCGCGCAGCTTCGATCGCTGGCGGCAGTTCGACGCCGGTCGGCAGGCACACGCGCGCGTGGCGCTGGAACGTATCGCGGA
GATCGAGGATCTAGCGAAGGACGTGGCGGAAGTTGTGGGGAATGCGCTAAAGGGTTGA

Upstream 100 bases:

>100_bases
GCGGCTTATGCTTCTGCCCTCACGACACGAGCGGTTTTCCGGAGCCCTGTTCCGAAAACCGCGTTCAGACTCGGCGCCCG
CCGCGCCGCCCGGAGATCTC

Downstream 100 bases:

>100_bases
TCGCAGTGCAAGAATCAGGTGGGCGGATTCTCGGACCAAGCGGTCAGCGGGAGGTTTTTGCCGGACGCGCCCCGACTTTG
CCGCTTGGTGGATGCCTTTT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 925; Mature: 925

Protein sequence:

>925_residues
MRTETPVTLYLKDYAPPAWRIESADLHVAIHDDHAEVRARLDCVRNTAGGDDALVLNGEALELVGLSLDGAPLDPARYVY
GDDLLRIAGPLPDRCVLESVVRIRPDLNTQLSGLYRSQDGYFTQCEPEGFRRITFFPDRPDVMTKFSCTVEADRARFPHL
LSNGNPVAAGVCDDDAARHWARWDDPYAKPCYLFALVAARLDVLEDEYVTASGRKVRLAVYVEPGKLDQCGHAMAALKKA
MRWDEERFGLEYDLDQYMIVAVGDFNMGAMENKGLNIFNTKYVLARPDTATDADYQGIDRVVAHEYFHNWTGNRVTCRDW
FQLSLKEGLTVFRDQEFGADTHSRAVTRIQEVRALRVGQFPEDVGPMAHPIRPASYAEINNFYTATVYNKGAEVIRMMHT
LLGREAFRRGTDLYFARHDGQAVTCEDFVAAMQDASGIDLAQFRRWYARAGTPRLNASSSYDATTRRYTLTLTQTLAPTA
YEKRLTESGQAIVDGTLHIPVALGLVLPNGNDAPLKLAGEAEASGTTRVLSLTEPTQTFVFEDIPAAPVASLLRDFSAPV
QLEFEQTDAELAHLMAHDDDAFNRWEAGQRLATRVLLAGIAAQQRAALMRHTLPHAGEDDSWRGAGSDWIPDAFVAACGR
VLDAGLAGDPALAAEALNLPAEAVLAEAVVSLGQPIDPEAIHAARVALRRHLAARLRDAFEAAWAALTPTAAYAPDGAQV
GQRALRNACLGYLAESDVEYLQSAVVPRLTAQLAAGGNMTDGNMTSQMAALATLANLDLPEREATLADFYTRWQNEALVV
DKWFAVQATSRLPGTAARVRALMQHPAFDLKNPNRVYALIRGFCGANPRHFHAFDGSGYALAADVISELQAINPQVASRI
ARSFDRWRQFDAGRQAHARVALERIAEIEDLAKDVAEVVGNALKG

Sequences:

>Translated_925_residues
MRTETPVTLYLKDYAPPAWRIESADLHVAIHDDHAEVRARLDCVRNTAGGDDALVLNGEALELVGLSLDGAPLDPARYVY
GDDLLRIAGPLPDRCVLESVVRIRPDLNTQLSGLYRSQDGYFTQCEPEGFRRITFFPDRPDVMTKFSCTVEADRARFPHL
LSNGNPVAAGVCDDDAARHWARWDDPYAKPCYLFALVAARLDVLEDEYVTASGRKVRLAVYVEPGKLDQCGHAMAALKKA
MRWDEERFGLEYDLDQYMIVAVGDFNMGAMENKGLNIFNTKYVLARPDTATDADYQGIDRVVAHEYFHNWTGNRVTCRDW
FQLSLKEGLTVFRDQEFGADTHSRAVTRIQEVRALRVGQFPEDVGPMAHPIRPASYAEINNFYTATVYNKGAEVIRMMHT
LLGREAFRRGTDLYFARHDGQAVTCEDFVAAMQDASGIDLAQFRRWYARAGTPRLNASSSYDATTRRYTLTLTQTLAPTA
YEKRLTESGQAIVDGTLHIPVALGLVLPNGNDAPLKLAGEAEASGTTRVLSLTEPTQTFVFEDIPAAPVASLLRDFSAPV
QLEFEQTDAELAHLMAHDDDAFNRWEAGQRLATRVLLAGIAAQQRAALMRHTLPHAGEDDSWRGAGSDWIPDAFVAACGR
VLDAGLAGDPALAAEALNLPAEAVLAEAVVSLGQPIDPEAIHAARVALRRHLAARLRDAFEAAWAALTPTAAYAPDGAQV
GQRALRNACLGYLAESDVEYLQSAVVPRLTAQLAAGGNMTDGNMTSQMAALATLANLDLPEREATLADFYTRWQNEALVV
DKWFAVQATSRLPGTAARVRALMQHPAFDLKNPNRVYALIRGFCGANPRHFHAFDGSGYALAADVISELQAINPQVASRI
ARSFDRWRQFDAGRQAHARVALERIAEIEDLAKDVAEVVGNALKG
>Mature_925_residues
MRTETPVTLYLKDYAPPAWRIESADLHVAIHDDHAEVRARLDCVRNTAGGDDALVLNGEALELVGLSLDGAPLDPARYVY
GDDLLRIAGPLPDRCVLESVVRIRPDLNTQLSGLYRSQDGYFTQCEPEGFRRITFFPDRPDVMTKFSCTVEADRARFPHL
LSNGNPVAAGVCDDDAARHWARWDDPYAKPCYLFALVAARLDVLEDEYVTASGRKVRLAVYVEPGKLDQCGHAMAALKKA
MRWDEERFGLEYDLDQYMIVAVGDFNMGAMENKGLNIFNTKYVLARPDTATDADYQGIDRVVAHEYFHNWTGNRVTCRDW
FQLSLKEGLTVFRDQEFGADTHSRAVTRIQEVRALRVGQFPEDVGPMAHPIRPASYAEINNFYTATVYNKGAEVIRMMHT
LLGREAFRRGTDLYFARHDGQAVTCEDFVAAMQDASGIDLAQFRRWYARAGTPRLNASSSYDATTRRYTLTLTQTLAPTA
YEKRLTESGQAIVDGTLHIPVALGLVLPNGNDAPLKLAGEAEASGTTRVLSLTEPTQTFVFEDIPAAPVASLLRDFSAPV
QLEFEQTDAELAHLMAHDDDAFNRWEAGQRLATRVLLAGIAAQQRAALMRHTLPHAGEDDSWRGAGSDWIPDAFVAACGR
VLDAGLAGDPALAAEALNLPAEAVLAEAVVSLGQPIDPEAIHAARVALRRHLAARLRDAFEAAWAALTPTAAYAPDGAQV
GQRALRNACLGYLAESDVEYLQSAVVPRLTAQLAAGGNMTDGNMTSQMAALATLANLDLPEREATLADFYTRWQNEALVV
DKWFAVQATSRLPGTAARVRALMQHPAFDLKNPNRVYALIRGFCGANPRHFHAFDGSGYALAADVISELQAINPQVASRI
ARSFDRWRQFDAGRQAHARVALERIAEIEDLAKDVAEVVGNALKG

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=396, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI132814467, Length=385, Percent_Identity=27.7922077922078, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI310123622, Length=331, Percent_Identity=28.3987915407855, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI61742775, Length=346, Percent_Identity=25.4335260115607, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI61742777, Length=346, Percent_Identity=25.4335260115607, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310133497, Length=333, Percent_Identity=28.8288288288288, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI94818891, Length=366, Percent_Identity=26.5027322404372, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI94818901, Length=366, Percent_Identity=26.5027322404372, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI194306629, Length=425, Percent_Identity=24.2352941176471, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI11641261, Length=425, Percent_Identity=24.2352941176471, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI157266300, Length=430, Percent_Identity=23.7209302325581, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4505029, Length=482, Percent_Identity=23.0290456431535, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI7019561, Length=314, Percent_Identity=27.3885350318471, Blast_Score=78, Evalue=5e-14,
Organism=Escherichia coli, GI1787163, Length=923, Percent_Identity=46.8039003250271, Blast_Score=774, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=440, Percent_Identity=27.0454545454545, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71989071, Length=440, Percent_Identity=27.0454545454545, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17569221, Length=356, Percent_Identity=28.6516853932584, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115533278, Length=376, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=376, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17569225, Length=318, Percent_Identity=27.0440251572327, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17565628, Length=229, Percent_Identity=33.6244541484716, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193206928, Length=396, Percent_Identity=24.7474747474747, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193206926, Length=396, Percent_Identity=24.7474747474747, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71990873, Length=322, Percent_Identity=24.223602484472, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71984353, Length=474, Percent_Identity=22.9957805907173, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71984339, Length=477, Percent_Identity=22.6415094339623, Blast_Score=73, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI133903840, Length=450, Percent_Identity=24.2222222222222, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=461, Percent_Identity=27.765726681128, Blast_Score=125, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321837, Length=397, Percent_Identity=27.455919395466, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24655257, Length=440, Percent_Identity=28.8636363636364, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24655252, Length=440, Percent_Identity=28.8636363636364, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24655274, Length=440, Percent_Identity=28.8636363636364, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24655260, Length=440, Percent_Identity=28.8636363636364, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24655265, Length=440, Percent_Identity=28.8636363636364, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24655268, Length=440, Percent_Identity=28.8636363636364, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24646514, Length=384, Percent_Identity=29.9479166666667, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646518, Length=417, Percent_Identity=28.7769784172662, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646516, Length=417, Percent_Identity=28.7769784172662, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24651016, Length=196, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24651025, Length=385, Percent_Identity=27.5324675324675, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24651023, Length=385, Percent_Identity=27.5324675324675, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24651021, Length=385, Percent_Identity=27.5324675324675, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21358341, Length=392, Percent_Identity=29.8469387755102, Blast_Score=116, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646510, Length=360, Percent_Identity=25, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646512, Length=360, Percent_Identity=25, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648786, Length=312, Percent_Identity=26.2820512820513, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571901, Length=307, Percent_Identity=27.3615635179153, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI161078673, Length=307, Percent_Identity=27.3615635179153, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221379089, Length=352, Percent_Identity=23.8636363636364, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45550850, Length=361, Percent_Identity=25.7617728531856, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24650973, Length=361, Percent_Identity=25.7617728531856, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648790, Length=238, Percent_Identity=27.7310924369748, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641062, Length=302, Percent_Identity=22.8476821192053, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571792, Length=351, Percent_Identity=22.7920227920228, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 101682; Mature: 101682

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTETPVTLYLKDYAPPAWRIESADLHVAIHDDHAEVRARLDCVRNTAGGDDALVLNGEA
CCCCCCEEEEEECCCCCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCE
LELVGLSLDGAPLDPARYVYGDDLLRIAGPLPDRCVLESVVRIRPDLNTQLSGLYRSQDG
EEEEEEECCCCCCCCCCEECCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHEECCCC
YFTQCEPEGFRRITFFPDRPDVMTKFSCTVEADRARFPHLLSNGNPVAAGVCDDDAARHW
CEEECCCCCCEEEEECCCCCCCEEEEEEEEECCHHHCCHHHCCCCEEEEECCCCHHHHHH
ARWDDPYAKPCYLFALVAARLDVLEDEYVTASGRKVRLAVYVEPGKLDQCGHAMAALKKA
HCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHH
MRWDEERFGLEYDLDQYMIVAVGDFNMGAMENKGLNIFNTKYVLARPDTATDADYQGIDR
HCCCHHHCCCEECCCCEEEEEEECCCCCCCCCCCCEEEECEEEEECCCCCCCCCHHHHHH
VVAHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFGADTHSRAVTRIQEVRALRVGQF
HHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PEDVGPMAHPIRPASYAEINNFYTATVYNKGAEVIRMMHTLLGREAFRRGTDLYFARHDG
CHHCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCC
QAVTCEDFVAAMQDASGIDLAQFRRWYARAGTPRLNASSSYDATTRRYTLTLTQTLAPTA
CEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEHHHCCHH
YEKRLTESGQAIVDGTLHIPVALGLVLPNGNDAPLKLAGEAEASGTTRVLSLTEPTQTFV
HHHHHHHCCCEEECCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCCHHHE
FEDIPAAPVASLLRDFSAPVQLEFEQTDAELAHLMAHDDDAFNRWEAGQRLATRVLLAGI
ECCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAQQRAALMRHTLPHAGEDDSWRGAGSDWIPDAFVAACGRVLDAGLAGDPALAAEALNLP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
AEAVLAEAVVSLGQPIDPEAIHAARVALRRHLAARLRDAFEAAWAALTPTAAYAPDGAQV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
GQRALRNACLGYLAESDVEYLQSAVVPRLTAQLAAGGNMTDGNMTSQMAALATLANLDLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
EREATLADFYTRWQNEALVVDKWFAVQATSRLPGTAARVRALMQHPAFDLKNPNRVYALI
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
RGFCGANPRHFHAFDGSGYALAADVISELQAINPQVASRIARSFDRWRQFDAGRQAHARV
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ALERIAEIEDLAKDVAEVVGNALKG
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTETPVTLYLKDYAPPAWRIESADLHVAIHDDHAEVRARLDCVRNTAGGDDALVLNGEA
CCCCCCEEEEEECCCCCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCE
LELVGLSLDGAPLDPARYVYGDDLLRIAGPLPDRCVLESVVRIRPDLNTQLSGLYRSQDG
EEEEEEECCCCCCCCCCEECCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHEECCCC
YFTQCEPEGFRRITFFPDRPDVMTKFSCTVEADRARFPHLLSNGNPVAAGVCDDDAARHW
CEEECCCCCCEEEEECCCCCCCEEEEEEEEECCHHHCCHHHCCCCEEEEECCCCHHHHHH
ARWDDPYAKPCYLFALVAARLDVLEDEYVTASGRKVRLAVYVEPGKLDQCGHAMAALKKA
HCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHH
MRWDEERFGLEYDLDQYMIVAVGDFNMGAMENKGLNIFNTKYVLARPDTATDADYQGIDR
HCCCHHHCCCEECCCCEEEEEEECCCCCCCCCCCCEEEECEEEEECCCCCCCCCHHHHHH
VVAHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFGADTHSRAVTRIQEVRALRVGQF
HHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PEDVGPMAHPIRPASYAEINNFYTATVYNKGAEVIRMMHTLLGREAFRRGTDLYFARHDG
CHHCCCCCCCCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCC
QAVTCEDFVAAMQDASGIDLAQFRRWYARAGTPRLNASSSYDATTRRYTLTLTQTLAPTA
CEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEHHHCCHH
YEKRLTESGQAIVDGTLHIPVALGLVLPNGNDAPLKLAGEAEASGTTRVLSLTEPTQTFV
HHHHHHHCCCEEECCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCCHHHE
FEDIPAAPVASLLRDFSAPVQLEFEQTDAELAHLMAHDDDAFNRWEAGQRLATRVLLAGI
ECCCCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAQQRAALMRHTLPHAGEDDSWRGAGSDWIPDAFVAACGRVLDAGLAGDPALAAEALNLP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
AEAVLAEAVVSLGQPIDPEAIHAARVALRRHLAARLRDAFEAAWAALTPTAAYAPDGAQV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
GQRALRNACLGYLAESDVEYLQSAVVPRLTAQLAAGGNMTDGNMTSQMAALATLANLDLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
EREATLADFYTRWQNEALVVDKWFAVQATSRLPGTAARVRALMQHPAFDLKNPNRVYALI
CHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
RGFCGANPRHFHAFDGSGYALAADVISELQAINPQVASRIARSFDRWRQFDAGRQAHARV
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ALERIAEIEDLAKDVAEVVGNALKG
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]