Click here to switch to the map view.

The map label for this gene is rnhB

Identifier: 74316817

GI number: 74316817

Start: 841944

End: 842558

Strand: Direct

Name: rnhB

Synonym: Tbd_0799

Alternate gene names: 74316817

Gene position: 841944-842558 (Clockwise)

Preceding gene: 74316816

Following gene: 74316818

Centisome position: 28.93

GC content: 70.08

Gene sequence:

>615_bases
ATGACAGGGCGTCGAACCGTCTCGCTGCACGTCGGTCCGGTCGGGCTGTGTGGCGTCGACGAGGCGGGACGGGGGCCGCT
CGCGGGTCCCGTCGTCGCCGCAGCGGTCATGCTCGACCCCAAGCGGCCGATCAAGGGGCTGCGCGATTCCAAGAAACTCA
CGCCGGCCGCGCGCGAGCGGCTCGCCGACGAGATCCGCGCGCGCGCGCTGGCCTGGTGCGTGGCCGAGGCGAGCGTCGCC
GAGATCGACCGGCTGAACATCCTGCATGCGACGATGCTCGCGATGCAGCGCGCGGTCGCCGGAATGTCGCACGCGCCGGA
CGACGTCTGGGTCGACGGCGACCGCTGTCCCGAGTGGACCTGGCGTTCGCAGGCCGTCGTTCAGGGGGACGACAAGGTCG
CGGCGATCGCTGCGGCGTCGATCCTCGCGAAAACCGTGCGTGACGAATTGATGCGCGGCCTTCACGAGGCGTATCCGCTG
TACGGCTTCGCGCAGCACATGGGCTACGCAACGGCTGCCCACCTCGCTGCGCTGAAGGCCAACGGCGCGTGCCCCCACCA
TCGCAGGAGTTTCGCGCCGGTCCGGCTCCTGCTCGATCAAACCTCGCTGTTCTGA

Upstream 100 bases:

>100_bases
CGGCGCTCGCTGTCACCTTCGACGCGCTGCATCGCGATCTGCGGCAGGGCGCGAGTGCGCGCATCGCCGCCGCGATCGCC
CCCTACCTCGAGGCCGCGCG

Downstream 100 bases:

>100_bases
AAGGAAGCTCGTGATCCCCTCGCTGTTTCTGCACGTTCTGAGCGTCGTCATCTGGGTCGGCGGCATGTTTTTCGCCTACA
TGGCGTTGCGGCCAGTGGCC

Product: RNase HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARERLADEIRARALAWCVAEASVA
EIDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWTWRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPL
YGFAQHMGYATAAHLAALKANGACPHHRRSFAPVRLLLDQTSLF

Sequences:

>Translated_204_residues
MTGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARERLADEIRARALAWCVAEASVA
EIDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWTWRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPL
YGFAQHMGYATAAHLAALKANGACPHHRRSFAPVRLLLDQTSLF
>Mature_203_residues
TGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARERLADEIRARALAWCVAEASVAE
IDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWTWRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPLY
GFAQHMGYATAAHLAALKANGACPHHRRSFAPVRLLLDQTSLF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=58.8888888888889, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_THIDA (Q3SKM7)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314557.1
- ProteinModelPortal:   Q3SKM7
- SMR:   Q3SKM7
- STRING:   Q3SKM7
- GeneID:   3673496
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0799
- NMPDR:   fig|292415.3.peg.106
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q3SKM7
- BioCyc:   TDEN292415:TBD_0799-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21958; Mature: 21826

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARER
CCCCEEEEEEECCEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHH
LADEIRARALAWCVAEASVAEIDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
WRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPLYGFAQHMGYATAAHLAALKA
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
NGACPHHRRSFAPVRLLLDQTSLF
CCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARER
CCCEEEEEEECCEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHH
LADEIRARALAWCVAEASVAEIDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
WRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPLYGFAQHMGYATAAHLAALKA
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
NGACPHHRRSFAPVRLLLDQTSLF
CCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA