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The map label for this gene is mshA [H]

Identifier: 74316758

GI number: 74316758

Start: 784173

End: 785501

Strand: Direct

Name: mshA [H]

Synonym: Tbd_0740

Alternate gene names: 74316758

Gene position: 784173-785501 (Clockwise)

Preceding gene: 74316757

Following gene: 74316759

Centisome position: 26.95

GC content: 69.9

Gene sequence:

>1329_bases
ATGTCACGACGCATTGCGCTCATCAGCGATCACGCTTCGCCGCTCGCGGTCCTCGGCGGCGTCGACAGCGGCGGCCAGAA
CGTCTACGTTGCGCAGGTCGCGCGCGAGCTCGCGGCGCGCGGACACGAGGTCGACGTGTTCACGCGCCGCTACCGCAGCG
GGCAGCCGCGCATCGTCGAGTGGTGCAGGAACGTGCGCGTCATCCATGTGCCGGCGGGGCCGGCGACCGACGTGCGCAAA
GAGGACCTGCTGCCTTACATGGCCGATTTCGCGCGCTGGATGATCGGCTTTTGCCGGATGCGGGGTGGCTACGACCTGCT
TCACGCCAACTTCTTCATGTCCGGCGTCGTCGCGCGGCAGGTGAGGCGCGCGCTCGGCACGCCGTTCGTGATTACCTTTC
ATGCCCTCGGCCGCGTGCGTCGCAAGTATCAGCGCGAGGCGGACGAGTTTCCCGACGAGCGCGCAGAGATCGAGGAGCAG
TTGGTCGCCGAAGCCGACGCGGTCATCGCCGAATGCCCGCAGGACAAATCCGACCTCGAGACGCTCTACGGTGCCGATCC
GGCCAGGCTCCACGTCGTGCCGTGCGGCTTCGAGAAGGACGCGTTCCTGCCGCTGCCGCGCCACTTCGCGCGCCAGGTGC
TCGGCATCGCGCCCGAAGAGCGCCTGCTCGTGAACGTCGGCAGGCTGGTGCCGCGCAAGGGCATCGACAACGCGATCCGT
GGCCTCGGTTGTCTGCGGCGCGTATACGGCATCGACGCGACGCTGCTCGTCGTCGGCGGCAATTCGGACGTCCCCGATCC
CCACGAGACGCCCGAGATCGGCCGGCTCGCCGAGGTCGCGGCGCACGACGCGGCCGGTCAGCGCGTGATCTTCACGGGGC
GGCGCTCGCGCGAATTGCTCAAGCTTTATTACGCGGCCGCGGACGCGCTCGTGACGACGCCCTGGTACGAGCCCTTCGGC
ATCACGCCGCTCGAAGCGATGGCCTGCGGGACGCCCGTGATCGGGTCCGACGTCGGCGGCCTCAAGTACACGATCCAGGA
CGGCGAGACCGGCTTTCTCGTTCCACCCGACGACCCCGAGGCGCTCGGCGAGCGCTTCGCGCGCTTCTACGGCAGCCCGC
GCCTGATGCGGCGCATGAGCCGCAGCGCGCTGCGCCGCGCCAACAGCTTGTTCACCTGGGACCGCGTCGTCGCCAGGCTC
GATCGTGTCTACGCGCGCGCGGCGCGATGGGACGCGCCGGCGGCAATCGTCACCCCGTTGCGTCCGCCGCGGGCGCTCCC
GCCCGAAGCCGAATTGCCCGGCGTGCTCGGAGGCGCGCTCTTGCCATGA

Upstream 100 bases:

>100_bases
AATCAATGGCTTACGAACGTTTCCGCGAGCCGGGGCATGGCGGTTGCTTTTTTGCCATTCAAGTTTCCCATTCGGAGCCA
CCCGTGTTTCGGGCGCCGCC

Downstream 100 bases:

>100_bases
CCCGCGCCGTGTTTCTCGACAAGGACGGCACGCTCGTCGACGACGTGCCGTACAACGCCGACCCGACGAAGATCCGGCTC
GCCGCGGGCGCCGGCCGCGC

Product: putative glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSRRIALISDHASPLAVLGGVDSGGQNVYVAQVARELAARGHEVDVFTRRYRSGQPRIVEWCRNVRVIHVPAGPATDVRK
EDLLPYMADFARWMIGFCRMRGGYDLLHANFFMSGVVARQVRRALGTPFVITFHALGRVRRKYQREADEFPDERAEIEEQ
LVAEADAVIAECPQDKSDLETLYGADPARLHVVPCGFEKDAFLPLPRHFARQVLGIAPEERLLVNVGRLVPRKGIDNAIR
GLGCLRRVYGIDATLLVVGGNSDVPDPHETPEIGRLAEVAAHDAAGQRVIFTGRRSRELLKLYYAAADALVTTPWYEPFG
ITPLEAMACGTPVIGSDVGGLKYTIQDGETGFLVPPDDPEALGERFARFYGSPRLMRRMSRSALRRANSLFTWDRVVARL
DRVYARAARWDAPAAIVTPLRPPRALPPEAELPGVLGGALLP

Sequences:

>Translated_442_residues
MSRRIALISDHASPLAVLGGVDSGGQNVYVAQVARELAARGHEVDVFTRRYRSGQPRIVEWCRNVRVIHVPAGPATDVRK
EDLLPYMADFARWMIGFCRMRGGYDLLHANFFMSGVVARQVRRALGTPFVITFHALGRVRRKYQREADEFPDERAEIEEQ
LVAEADAVIAECPQDKSDLETLYGADPARLHVVPCGFEKDAFLPLPRHFARQVLGIAPEERLLVNVGRLVPRKGIDNAIR
GLGCLRRVYGIDATLLVVGGNSDVPDPHETPEIGRLAEVAAHDAAGQRVIFTGRRSRELLKLYYAAADALVTTPWYEPFG
ITPLEAMACGTPVIGSDVGGLKYTIQDGETGFLVPPDDPEALGERFARFYGSPRLMRRMSRSALRRANSLFTWDRVVARL
DRVYARAARWDAPAAIVTPLRPPRALPPEAELPGVLGGALLP
>Mature_441_residues
SRRIALISDHASPLAVLGGVDSGGQNVYVAQVARELAARGHEVDVFTRRYRSGQPRIVEWCRNVRVIHVPAGPATDVRKE
DLLPYMADFARWMIGFCRMRGGYDLLHANFFMSGVVARQVRRALGTPFVITFHALGRVRRKYQREADEFPDERAEIEEQL
VAEADAVIAECPQDKSDLETLYGADPARLHVVPCGFEKDAFLPLPRHFARQVLGIAPEERLLVNVGRLVPRKGIDNAIRG
LGCLRRVYGIDATLLVVGGNSDVPDPHETPEIGRLAEVAAHDAAGQRVIFTGRRSRELLKLYYAAADALVTTPWYEPFGI
TPLEAMACGTPVIGSDVGGLKYTIQDGETGFLVPPDDPEALGERFARFYGSPRLMRRMSRSALRRANSLFTWDRVVARLD
RVYARAARWDAPAAIVTPLRPPRALPPEAELPGVLGGALLP

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790061, Length=355, Percent_Identity=27.3239436619718, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32564184, Length=160, Percent_Identity=29.375, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 48857; Mature: 48726

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIALISDHASPLAVLGGVDSGGQNVYVAQVARELAARGHEVDVFTRRYRSGQPRIVE
CCCEEEEEECCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
WCRNVRVIHVPAGPATDVRKEDLLPYMADFARWMIGFCRMRGGYDLLHANFFMSGVVARQ
HHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VRRALGTPFVITFHALGRVRRKYQREADEFPDERAEIEEQLVAEADAVIAECPQDKSDLE
HHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TLYGADPARLHVVPCGFEKDAFLPLPRHFARQVLGIAPEERLLVNVGRLVPRKGIDNAIR
HHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
GLGCLRRVYGIDATLLVVGGNSDVPDPHETPEIGRLAEVAAHDAAGQRVIFTGRRSRELL
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
KLYYAAADALVTTPWYEPFGITPLEAMACGTPVIGSDVGGLKYTIQDGETGFLVPPDDPE
HHHHHHHHHHEECCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEECCCCHH
ALGERFARFYGSPRLMRRMSRSALRRANSLFTWDRVVARLDRVYARAARWDAPAAIVTPL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
RPPRALPPEAELPGVLGGALLP
CCCCCCCCCCCCCCHHCCCCCC
>Mature Secondary Structure 
SRRIALISDHASPLAVLGGVDSGGQNVYVAQVARELAARGHEVDVFTRRYRSGQPRIVE
CCEEEEEECCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
WCRNVRVIHVPAGPATDVRKEDLLPYMADFARWMIGFCRMRGGYDLLHANFFMSGVVARQ
HHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VRRALGTPFVITFHALGRVRRKYQREADEFPDERAEIEEQLVAEADAVIAECPQDKSDLE
HHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TLYGADPARLHVVPCGFEKDAFLPLPRHFARQVLGIAPEERLLVNVGRLVPRKGIDNAIR
HHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHH
GLGCLRRVYGIDATLLVVGGNSDVPDPHETPEIGRLAEVAAHDAAGQRVIFTGRRSRELL
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
KLYYAAADALVTTPWYEPFGITPLEAMACGTPVIGSDVGGLKYTIQDGETGFLVPPDDPE
HHHHHHHHHHEECCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEECCCCHH
ALGERFARFYGSPRLMRRMSRSALRRANSLFTWDRVVARLDRVYARAARWDAPAAIVTPL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
RPPRALPPEAELPGVLGGALLP
CCCCCCCCCCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA