Click here to switch to the map view.

The map label for this gene is exbB [H]

Identifier: 74316730

GI number: 74316730

Start: 750423

End: 751175

Strand: Reverse

Name: exbB [H]

Synonym: Tbd_0712

Alternate gene names: 74316730

Gene position: 751175-750423 (Counterclockwise)

Preceding gene: 74316731

Following gene: 74316729

Centisome position: 25.82

GC content: 67.46

Gene sequence:

>753_bases
ATGCCAACCGCCGCCCCCACCCAACTGGGCTTCGCCCACTTCATCGCCCAGGCCGACGGGCTCGCGCATTTCCTGCTCGT
CGTGCTGCTCGCGATGTCGGTCGTCACCTGGACGCTCATCGTCGCCAAAAGCGTCGGCAACTGGCGCATGAAGCAACACG
CACGGGCCTTCCTCGCGCACTTCTGGAATGCCCCCGGCCTGCCCGCGGTCGCCGACCATCTGCAGAAGCACGGCGTCAAG
GATCCGTTCTCGCACCTGACCCATCACGGCCTCAAGGCCGCCGAGCAGTACCGCAACCGCTCGGGCCAGCGCCTGATCGA
GTCGGGCTCGGAAGACGAATTCCTGACCCGCGCGCTGCGCCGTGCGATCAATCAGGACACGGCGCGTCTCGAATACGGCC
ACACCATGCTCGCGTCGATCGCGTCCTCCGCGCCCTTCGTCGGCCTGTTCGGCACGGTCTGGGGCATCTACCACGCCCTG
GTCAACATCGGCATGTCGGGCTCGGGCAGCCTCGACCAGGTCGCCGGGCCAGTCGGCGAGGCACTGATCATGACCGCGCT
CGGCCTCGCGGTCGCGATCCCCGCCGTGCTCGCGTACAACTTCTTCAATCGCGCCCGCCGCGAGATGCTGTCCGAGGTCG
ACGGCTTCGCGCACGACCTCTTCGCCTTCATGTCGACCGGCGTGCGCAGCGATACGCGGATCGAAAAGGACGCGCCGCAG
ATCTACGCAGCGCCCGTCGCAAGGAGCGTGTGA

Upstream 100 bases:

>100_bases
CGGTGCAGTCGAGCTGGAAATTCGAGCCGGCCCGCCAGGGCGGCAGCCCGGTGGCCGCGTGGGTCATCGTGCCGATTCAA
TTCACGCTCAGGAGCTAAGC

Downstream 100 bases:

>100_bases
TGGCCTTCGGCGGACTCTCGGCCGGCAGCGGCGACAGCGACAACGCGGAGATCAACATGATCCCGCTGATCGACGTGATG
CTCGTGCTGCTCGTCATCTT

Product: MotA/TolQ/ExbB proton channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPTAAPTQLGFAHFIAQADGLAHFLLVVLLAMSVVTWTLIVAKSVGNWRMKQHARAFLAHFWNAPGLPAVADHLQKHGVK
DPFSHLTHHGLKAAEQYRNRSGQRLIESGSEDEFLTRALRRAINQDTARLEYGHTMLASIASSAPFVGLFGTVWGIYHAL
VNIGMSGSGSLDQVAGPVGEALIMTALGLAVAIPAVLAYNFFNRARREMLSEVDGFAHDLFAFMSTGVRSDTRIEKDAPQ
IYAAPVARSV

Sequences:

>Translated_250_residues
MPTAAPTQLGFAHFIAQADGLAHFLLVVLLAMSVVTWTLIVAKSVGNWRMKQHARAFLAHFWNAPGLPAVADHLQKHGVK
DPFSHLTHHGLKAAEQYRNRSGQRLIESGSEDEFLTRALRRAINQDTARLEYGHTMLASIASSAPFVGLFGTVWGIYHAL
VNIGMSGSGSLDQVAGPVGEALIMTALGLAVAIPAVLAYNFFNRARREMLSEVDGFAHDLFAFMSTGVRSDTRIEKDAPQ
IYAAPVARSV
>Mature_249_residues
PTAAPTQLGFAHFIAQADGLAHFLLVVLLAMSVVTWTLIVAKSVGNWRMKQHARAFLAHFWNAPGLPAVADHLQKHGVKD
PFSHLTHHGLKAAEQYRNRSGQRLIESGSEDEFLTRALRRAINQDTARLEYGHTMLASIASSAPFVGLFGTVWGIYHALV
NIGMSGSGSLDQVAGPVGEALIMTALGLAVAIPAVLAYNFFNRARREMLSEVDGFAHDLFAFMSTGVRSDTRIEKDAPQI
YAAPVARSV

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=224, Percent_Identity=28.125, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789381, Length=192, Percent_Identity=32.2916666666667, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 27131; Mature: 26999

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAAPTQLGFAHFIAQADGLAHFLLVVLLAMSVVTWTLIVAKSVGNWRMKQHARAFLAH
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FWNAPGLPAVADHLQKHGVKDPFSHLTHHGLKAAEQYRNRSGQRLIESGSEDEFLTRALR
HHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
RAINQDTARLEYGHTMLASIASSAPFVGLFGTVWGIYHALVNIGMSGSGSLDQVAGPVGE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALIMTALGLAVAIPAVLAYNFFNRARREMLSEVDGFAHDLFAFMSTGVRSDTRIEKDAPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IYAAPVARSV
HHHHHHHCCC
>Mature Secondary Structure 
PTAAPTQLGFAHFIAQADGLAHFLLVVLLAMSVVTWTLIVAKSVGNWRMKQHARAFLAH
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FWNAPGLPAVADHLQKHGVKDPFSHLTHHGLKAAEQYRNRSGQRLIESGSEDEFLTRALR
HHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
RAINQDTARLEYGHTMLASIASSAPFVGLFGTVWGIYHALVNIGMSGSGSLDQVAGPVGE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALIMTALGLAVAIPAVLAYNFFNRARREMLSEVDGFAHDLFAFMSTGVRSDTRIEKDAPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IYAAPVARSV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]