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The map label for this gene is apbE [H]

Identifier: 74316726

GI number: 74316726

Start: 747566

End: 748429

Strand: Reverse

Name: apbE [H]

Synonym: Tbd_0708

Alternate gene names: 74316726

Gene position: 748429-747566 (Counterclockwise)

Preceding gene: 74316727

Following gene: 74316725

Centisome position: 25.72

GC content: 72.69

Gene sequence:

>864_bases
GTGATTTCGCGACGCGCCCAGCCCTGGCTCGGCACCTTGGTCGAAATCGTCGCCGAGGGGGCGGACGACGCGACGCTGAT
CGCCGCGTCCGATCGCGCCTTCGCGCGCATCGCCGCGGTTCATGCGCAGATGAGTTTCCAGGCCGCCGACTCCGCGCTGT
CGCGCGTCAACCGCGACGCGCAGCACGACTGGGTCACGCTGTCGCCTGATCTTGCCGCCGTGTTCGCCGCAGCGCTGGCG
TTCGCGCGCGCGAGCGACGGTTTGTTCGACCCGAGCGTCGCAGGGCGGCTCGTCGAATCGGGCCAGTTGCCGCGGCACAC
CGGCTTCCCGGACGCGACGACGACCGACTGGCGCGGTATCGAACTCGACGGCGACCGCGTGCGCTACACGCAGCCGCTGC
TCGTCGACCTCTCGGGCATCGCCAAGGGCTATGCGGTCGACGTGGCGCTCACGAGCCTGCGCGACGCGGGCCTCGCGGCC
GCCACCGTAAACGCCGGCGGCGATCTCGCGCGCTTCGGCGGCGCGACGCCGATTCACGTCCGCCTGCCGCAGCAGCCGAC
GCAGAGCGTGCGGCTCGCCGAACTCGACCACGGTGCAGCCGCGACCTCGGCCGGCTATTTCCAGCCCGGCGCGCTGCGCC
ATCCGCGCAGCGGCGAAGCACTGTGCGCCGAGACCAGCGTCACCGTGCTCGCGCCTGACTGCATGACGGCTGACGCGCTG
ACCAAGGTCGTCGCGGCCGACTCGGCCTGCGCCGCCGGCGTGCTCGCGCGCCATGGCGCGCAGGCCATCGTGCTCGACGG
CCAACGCGCGATATGCAGCGATGCCGACGGCTGGCACGACCTGCCCGCGGGAGGCACGGCGTGA

Upstream 100 bases:

>100_bases
TGGACGACGACATCCAGAACATCAGCGGCGCGACGCTTTCGTGCAAACACATCAGCGAGGGCGTGCGGCGCGTGCTCGCG
ATCCACGAGGTGGCCTTGAA

Downstream 100 bases:

>100_bases
GCGCACTGACCATTCGTCTCGGTGCGCGCCACAGGCGGCTCACTTACGCGACCTTCGCCCTGCTCTGGACGAGCGGCGCG
CTGTGGCTGGCGTTCCATTA

Product: thiamine biosynthesis lipoprotein apbE transmembrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MISRRAQPWLGTLVEIVAEGADDATLIAASDRAFARIAAVHAQMSFQAADSALSRVNRDAQHDWVTLSPDLAAVFAAALA
FARASDGLFDPSVAGRLVESGQLPRHTGFPDATTTDWRGIELDGDRVRYTQPLLVDLSGIAKGYAVDVALTSLRDAGLAA
ATVNAGGDLARFGGATPIHVRLPQQPTQSVRLAELDHGAAATSAGYFQPGALRHPRSGEALCAETSVTVLAPDCMTADAL
TKVVAADSACAAGVLARHGAQAIVLDGQRAICSDADGWHDLPAGGTA

Sequences:

>Translated_287_residues
MISRRAQPWLGTLVEIVAEGADDATLIAASDRAFARIAAVHAQMSFQAADSALSRVNRDAQHDWVTLSPDLAAVFAAALA
FARASDGLFDPSVAGRLVESGQLPRHTGFPDATTTDWRGIELDGDRVRYTQPLLVDLSGIAKGYAVDVALTSLRDAGLAA
ATVNAGGDLARFGGATPIHVRLPQQPTQSVRLAELDHGAAATSAGYFQPGALRHPRSGEALCAETSVTVLAPDCMTADAL
TKVVAADSACAAGVLARHGAQAIVLDGQRAICSDADGWHDLPAGGTA
>Mature_287_residues
MISRRAQPWLGTLVEIVAEGADDATLIAASDRAFARIAAVHAQMSFQAADSALSRVNRDAQHDWVTLSPDLAAVFAAALA
FARASDGLFDPSVAGRLVESGQLPRHTGFPDATTTDWRGIELDGDRVRYTQPLLVDLSGIAKGYAVDVALTSLRDAGLAA
ATVNAGGDLARFGGATPIHVRLPQQPTQSVRLAELDHGAAATSAGYFQPGALRHPRSGEALCAETSVTVLAPDCMTADAL
TKVVAADSACAAGVLARHGAQAIVLDGQRAICSDADGWHDLPAGGTA

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 29640; Mature: 29640

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRRAQPWLGTLVEIVAEGADDATLIAASDRAFARIAAVHAQMSFQAADSALSRVNRDA
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QHDWVTLSPDLAAVFAAALAFARASDGLFDPSVAGRLVESGQLPRHTGFPDATTTDWRGI
CCCEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
ELDGDRVRYTQPLLVDLSGIAKGYAVDVALTSLRDAGLAAATVNAGGDLARFGGATPIHV
EECCCEEEECCCCEEEHHHHCCCEEEEHHHHHHHCCCCEEEEECCCCCHHHHCCCCEEEE
RLPQQPTQSVRLAELDHGAAATSAGYFQPGALRHPRSGEALCAETSVTVLAPDCMTADAL
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCHHHH
TKVVAADSACAAGVLARHGAQAIVLDGQRAICSDADGWHDLPAGGTA
HHHHHCCCHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MISRRAQPWLGTLVEIVAEGADDATLIAASDRAFARIAAVHAQMSFQAADSALSRVNRDA
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QHDWVTLSPDLAAVFAAALAFARASDGLFDPSVAGRLVESGQLPRHTGFPDATTTDWRGI
CCCEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
ELDGDRVRYTQPLLVDLSGIAKGYAVDVALTSLRDAGLAAATVNAGGDLARFGGATPIHV
EECCCEEEECCCCEEEHHHHCCCEEEEHHHHHHHCCCCEEEEECCCCCHHHHCCCCEEEE
RLPQQPTQSVRLAELDHGAAATSAGYFQPGALRHPRSGEALCAETSVTVLAPDCMTADAL
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCHHHH
TKVVAADSACAAGVLARHGAQAIVLDGQRAICSDADGWHDLPAGGTA
HHHHHCCCHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]