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The map label for this gene is rio1 [H]

Identifier: 74316629

GI number: 74316629

Start: 640033

End: 640881

Strand: Reverse

Name: rio1 [H]

Synonym: Tbd_0611

Alternate gene names: 74316629

Gene position: 640881-640033 (Counterclockwise)

Preceding gene: 74316630

Following gene: 74316618

Centisome position: 22.02

GC content: 65.02

Gene sequence:

>849_bases
ATGAAGATCCCCAGGCGGCTCGAACCCCTGCTCGAAGACGGCCTGATCGACGGCGTCGTGCGTCAGCTCATGAGCGGCAA
GGAGGCGATGGTCTTCGCCGTGCGCTGCGGCGACGAAATCCGCTGCGCCAAGGTCTACAAGGAAGCCAACAAGCGCAGCT
TCCGCCAGGCCGTCGACTACACCGAGAACCGCAAGACCAAGAACAGCCGCCAGGCACGCGCCATGGCCAAGGGCAGCAAG
TACGGCCGCCAGATGCAGGAAGCCGCCTGGCAGAGCGCCGAAGTCGACGCGTTATACCGACTCGCCGCTGCCGGCGTACG
CGTGCCCACGCCTTATAACTTCCATGAAGGCGTGCTGCTGATGGAACTGGTCGCCGATGCCGACGGCAACGCCGCGCCCC
GGCTCAACGACGTGTCGTTCACCGAAGGCGAAGCGCTCGCCCACCACCAAACGTTAATCAGGGAAGTCGTGCGCATGCTG
TGCGCGGGCGTCGTCCACGGTGACCTGTCCGAGTTCAACATCCTCGTCGGTGCCGACGGCCCGGTGATCATCGACCTGCC
GCAGGCGGTCGACGCGGCCGGCAACAACCACGCGCAAGCGATGCTGATGCGCGACGTACACAACCTAAGGGGATACTTTG
GGCAGTTCGCGCCGGCGCTGCTCACCACGCGCTACGCCGAGGAAATCTGGGCACTCTACGAGCACGGCAGCCTGCATCCC
GAGGTCGCGCTCAGCGGCCAGTTCGAGTGTGAAATGCCGCCGGTCGATCTGGAAGGCGTGATGCGGGAGATCGACGACGC
GCGAGAGCAAGAGGCGGCGCGCCTGTTGCGCTTGCAGGAACTGTCGTAA

Upstream 100 bases:

>100_bases
CGTTTCTTCGGGCTGACCACGCTGGGCGACGACTTCGAGGGCAGCGCGATCCACCGGCGCCTGCTGGAGGCGTACCGCAA
GGTGCGCGGCTAAAGCCCAA

Downstream 100 bases:

>100_bases
AAACGCCCCGGTTCGGCCGGGGCGTATGGCTCGGGTTCAGCCCAGTTTACTTGGCGCGGGGCATTGGACCGCTCATGCCC
TGGTGCTGCATCATCTGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIPRRLEPLLEDGLIDGVVRQLMSGKEAMVFAVRCGDEIRCAKVYKEANKRSFRQAVDYTENRKTKNSRQARAMAKGSK
YGRQMQEAAWQSAEVDALYRLAAAGVRVPTPYNFHEGVLLMELVADADGNAAPRLNDVSFTEGEALAHHQTLIREVVRML
CAGVVHGDLSEFNILVGADGPVIIDLPQAVDAAGNNHAQAMLMRDVHNLRGYFGQFAPALLTTRYAEEIWALYEHGSLHP
EVALSGQFECEMPPVDLEGVMREIDDAREQEAARLLRLQELS

Sequences:

>Translated_282_residues
MKIPRRLEPLLEDGLIDGVVRQLMSGKEAMVFAVRCGDEIRCAKVYKEANKRSFRQAVDYTENRKTKNSRQARAMAKGSK
YGRQMQEAAWQSAEVDALYRLAAAGVRVPTPYNFHEGVLLMELVADADGNAAPRLNDVSFTEGEALAHHQTLIREVVRML
CAGVVHGDLSEFNILVGADGPVIIDLPQAVDAAGNNHAQAMLMRDVHNLRGYFGQFAPALLTTRYAEEIWALYEHGSLHP
EVALSGQFECEMPPVDLEGVMREIDDAREQEAARLLRLQELS
>Mature_282_residues
MKIPRRLEPLLEDGLIDGVVRQLMSGKEAMVFAVRCGDEIRCAKVYKEANKRSFRQAVDYTENRKTKNSRQARAMAKGSK
YGRQMQEAAWQSAEVDALYRLAAAGVRVPTPYNFHEGVLLMELVADADGNAAPRLNDVSFTEGEALAHHQTLIREVVRML
CAGVVHGDLSEFNILVGADGPVIIDLPQAVDAAGNNHAQAMLMRDVHNLRGYFGQFAPALLTTRYAEEIWALYEHGSLHP
EVALSGQFECEMPPVDLEGVMREIDDAREQEAARLLRLQELS

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=217, Percent_Identity=30.8755760368664, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI23510358, Length=137, Percent_Identity=33.5766423357664, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI22325377, Length=212, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532073, Length=222, Percent_Identity=29.2792792792793, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17556977, Length=221, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662811, Length=225, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356879, Length=225, Percent_Identity=29.3333333333333, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR000687
- InterPro:   IPR018935
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31375; Mature: 31375

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPRRLEPLLEDGLIDGVVRQLMSGKEAMVFAVRCGDEIRCAKVYKEANKRSFRQAVDY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TENRKTKNSRQARAMAKGSKYGRQMQEAAWQSAEVDALYRLAAAGVRVPTPYNFHEGVLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCHHHH
MELVADADGNAAPRLNDVSFTEGEALAHHQTLIREVVRMLCAGVVHGDLSEFNILVGADG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PVIIDLPQAVDAAGNNHAQAMLMRDVHNLRGYFGQFAPALLTTRYAEEIWALYEHGSLHP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVALSGQFECEMPPVDLEGVMREIDDAREQEAARLLRLQELS
CEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIPRRLEPLLEDGLIDGVVRQLMSGKEAMVFAVRCGDEIRCAKVYKEANKRSFRQAVDY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TENRKTKNSRQARAMAKGSKYGRQMQEAAWQSAEVDALYRLAAAGVRVPTPYNFHEGVLL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCHHHH
MELVADADGNAAPRLNDVSFTEGEALAHHQTLIREVVRMLCAGVVHGDLSEFNILVGADG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PVIIDLPQAVDAAGNNHAQAMLMRDVHNLRGYFGQFAPALLTTRYAEEIWALYEHGSLHP
CEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVALSGQFECEMPPVDLEGVMREIDDAREQEAARLLRLQELS
CEEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]