Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 74316530

GI number: 74316530

Start: 540870

End: 542342

Strand: Direct

Name: tldD [H]

Synonym: Tbd_0512

Alternate gene names: 74316530

Gene position: 540870-542342 (Clockwise)

Preceding gene: 74316529

Following gene: 74316531

Centisome position: 18.59

GC content: 67.07

Gene sequence:

>1473_bases
ATGAACCCGACCGACGCCTTCGTTCCGATCCAGTCCGCCGAACAGCTGTTCCGTTCGGCCGAAGCCACCCTGCTGACGCC
GAACGGCCTCGACGCCGACAAGCTCGCACCGGTGTTCGGCCGTCTGCTCACGCACGACGTCGACTACGCCGACCTCTACT
TCCAGTACAGCCGCTCCGAGGGCTGGAGCCTTGAGGAAGGCCAGGTCAAATCGGGCAGCTTCAACATCGACCAGGGCGTC
GGCGTGCGGGCGATCTGCGGCGAGAAGACCGCCTTCGCCTATTCCGACGACATCAGTCTCGACGCGCTCGGCGCCGCGGC
CGACGCGACGCGCGCGATCGCGCGGGCCGGACAGAACCGCAGCTTCGGCATGGTGCACCGCGGCGAAGGCCGTCTGCTCT
ACAACGCGGTCGATCCGCTCGTGAGCCTCGACGATGCAGCCAAGGTCGCGCTGCTCGAACGGCTCGAAAAGAAGGCGCGC
GCGATGGATCCGCGTGTGATCCAGGTCATGGCAAGCCTCGCCTCGGAATACGAAGTCGTCTTCATCGCGCGTTCCGACGG
CCATCTCGCGGCCGACGTACGCCCGCTCGTACGCCTGTCGCTGCAGGTCATCGCCGAGCAGGACGGCCGGCGCGAGCAGG
GCTCGGGCGGTGGCGGTGGGCGCTTCGACTACAGTTATTTCACCGACGACATCCTCGAGAAATACGCGCGCCAGGCCGTG
CATCAGGCGAGCGTCAATCTCGAGGCGCGCCCGGCCCCTGCGGGCAGCATGACCGTCGTTCTCGGCGCCGGCTGGCCCGG
CATCCTGCTGCACGAGGCGATCGGACACGGCCTCGAAGGCGACTTCAACCGCAAGGGCAGCTCGGCCTTTTCCGGCCGCA
TCGGCGAGCGCGTCGCCGCCCCCGGCGTGACCGTCGTCGACGACGGTACGATCCCGCTCAGACGCGGCTCGCTCAACGTC
GACGACGAAGGCAACCCGACCCAGCGCACCACGCTGATCGAGGACGGCGTCCTCACCGGCTACATGCAGGACATGATGAA
CGCGCGGCTCATGGGCATGCAGCCGACCGGCAACGCGCGCCGCGAATCCTTCGCCCACCTGACCATGCCGCGCATGACCA
ACACCCTCATGCTCGGCGGCGACAAGCATCCGCACGAGATCATCGCCTCGGTCAAGAACGGCCTCTACGCCGTCAACTTC
GGCGGCGGCCAGGTCGACATCACGAGCGGCAAGTTCGTCTTCTCCGCCGCCGAGGCTTACATGATCGAGAACGGCAAGAT
CAGCTATCCGGTGAAAGGCGCCACCCTCATCGGCAACGGCCCCGAGGTGCTGACGCGCGTCTCGATGATCGGCAACGACA
TGGAGATGGATTCCGGCGTCGGGACGTGCGGGAAGGAGGGGCAGAGCGTGCCGGTCGGGGTGGGACAGCCGACGCTGAGG
ATTGATGGGTTGACGGTTGGCGGAACGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGCAGCATCGCTTCATCCCCTGTCAGCAGATAGCGGTCGATGTCGTCGAGCGGCGCGCCGTGGCCAAACGCGAGCCC
ACGAGCAAACAGGACAAGCC

Downstream 100 bases:

>100_bases
CAGCGTCTAAAAAGAACAAGCAGCGCGGCGCACCGCTAGAGGGGCGTCCGGATAACAAGAAAACGCATAACAACCTGAGG
AGGAGAAATCATGCGTGCAT

Product: putative modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNPTDAFVPIQSAEQLFRSAEATLLTPNGLDADKLAPVFGRLLTHDVDYADLYFQYSRSEGWSLEEGQVKSGSFNIDQGV
GVRAICGEKTAFAYSDDISLDALGAAADATRAIARAGQNRSFGMVHRGEGRLLYNAVDPLVSLDDAAKVALLERLEKKAR
AMDPRVIQVMASLASEYEVVFIARSDGHLAADVRPLVRLSLQVIAEQDGRREQGSGGGGGRFDYSYFTDDILEKYARQAV
HQASVNLEARPAPAGSMTVVLGAGWPGILLHEAIGHGLEGDFNRKGSSAFSGRIGERVAAPGVTVVDDGTIPLRRGSLNV
DDEGNPTQRTTLIEDGVLTGYMQDMMNARLMGMQPTGNARRESFAHLTMPRMTNTLMLGGDKHPHEIIASVKNGLYAVNF
GGGQVDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPEVLTRVSMIGNDMEMDSGVGTCGKEGQSVPVGVGQPTLR
IDGLTVGGTA

Sequences:

>Translated_490_residues
MNPTDAFVPIQSAEQLFRSAEATLLTPNGLDADKLAPVFGRLLTHDVDYADLYFQYSRSEGWSLEEGQVKSGSFNIDQGV
GVRAICGEKTAFAYSDDISLDALGAAADATRAIARAGQNRSFGMVHRGEGRLLYNAVDPLVSLDDAAKVALLERLEKKAR
AMDPRVIQVMASLASEYEVVFIARSDGHLAADVRPLVRLSLQVIAEQDGRREQGSGGGGGRFDYSYFTDDILEKYARQAV
HQASVNLEARPAPAGSMTVVLGAGWPGILLHEAIGHGLEGDFNRKGSSAFSGRIGERVAAPGVTVVDDGTIPLRRGSLNV
DDEGNPTQRTTLIEDGVLTGYMQDMMNARLMGMQPTGNARRESFAHLTMPRMTNTLMLGGDKHPHEIIASVKNGLYAVNF
GGGQVDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPEVLTRVSMIGNDMEMDSGVGTCGKEGQSVPVGVGQPTLR
IDGLTVGGTA
>Mature_490_residues
MNPTDAFVPIQSAEQLFRSAEATLLTPNGLDADKLAPVFGRLLTHDVDYADLYFQYSRSEGWSLEEGQVKSGSFNIDQGV
GVRAICGEKTAFAYSDDISLDALGAAADATRAIARAGQNRSFGMVHRGEGRLLYNAVDPLVSLDDAAKVALLERLEKKAR
AMDPRVIQVMASLASEYEVVFIARSDGHLAADVRPLVRLSLQVIAEQDGRREQGSGGGGGRFDYSYFTDDILEKYARQAV
HQASVNLEARPAPAGSMTVVLGAGWPGILLHEAIGHGLEGDFNRKGSSAFSGRIGERVAAPGVTVVDDGTIPLRRGSLNV
DDEGNPTQRTTLIEDGVLTGYMQDMMNARLMGMQPTGNARRESFAHLTMPRMTNTLMLGGDKHPHEIIASVKNGLYAVNF
GGGQVDITSGKFVFSAAEAYMIENGKISYPVKGATLIGNGPEVLTRVSMIGNDMEMDSGVGTCGKEGQSVPVGVGQPTLR
IDGLTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=475, Percent_Identity=60.6315789473684, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790682, Length=411, Percent_Identity=25.0608272506083, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52187; Mature: 52187

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTDAFVPIQSAEQLFRSAEATLLTPNGLDADKLAPVFGRLLTHDVDYADLYFQYSRSE
CCCCCCEEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
GWSLEEGQVKSGSFNIDQGVGVRAICGEKTAFAYSDDISLDALGAAADATRAIARAGQNR
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCC
SFGMVHRGEGRLLYNAVDPLVSLDDAAKVALLERLEKKARAMDPRVIQVMASLASEYEVV
CCCEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEE
FIARSDGHLAADVRPLVRLSLQVIAEQDGRREQGSGGGGGRFDYSYFTDDILEKYARQAV
EEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HQASVNLEARPAPAGSMTVVLGAGWPGILLHEAIGHGLEGDFNRKGSSAFSGRIGERVAA
HHHHCCEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHCC
PGVTVVDDGTIPLRRGSLNVDDEGNPTQRTTLIEDGVLTGYMQDMMNARLMGMQPTGNAR
CCCEEEECCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEEECCCCCCHH
RESFAHLTMPRMTNTLMLGGDKHPHEIIASVKNGLYAVNFGGGQVDITSGKFVFSAAEAY
HHHHHHEECCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEE
MIENGKISYPVKGATLIGNGPEVLTRVSMIGNDMEMDSGVGTCGKEGQSVPVGVGQPTLR
EEECCEEECCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
IDGLTVGGTA
ECCEECCCCC
>Mature Secondary Structure
MNPTDAFVPIQSAEQLFRSAEATLLTPNGLDADKLAPVFGRLLTHDVDYADLYFQYSRSE
CCCCCCEEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCC
GWSLEEGQVKSGSFNIDQGVGVRAICGEKTAFAYSDDISLDALGAAADATRAIARAGQNR
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCC
SFGMVHRGEGRLLYNAVDPLVSLDDAAKVALLERLEKKARAMDPRVIQVMASLASEYEVV
CCCEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEE
FIARSDGHLAADVRPLVRLSLQVIAEQDGRREQGSGGGGGRFDYSYFTDDILEKYARQAV
EEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HQASVNLEARPAPAGSMTVVLGAGWPGILLHEAIGHGLEGDFNRKGSSAFSGRIGERVAA
HHHHCCEEECCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHCC
PGVTVVDDGTIPLRRGSLNVDDEGNPTQRTTLIEDGVLTGYMQDMMNARLMGMQPTGNAR
CCCEEEECCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEEECCCCCCHH
RESFAHLTMPRMTNTLMLGGDKHPHEIIASVKNGLYAVNFGGGQVDITSGKFVFSAAEAY
HHHHHHEECCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEE
MIENGKISYPVKGATLIGNGPEVLTRVSMIGNDMEMDSGVGTCGKEGQSVPVGVGQPTLR
EEECCEEECCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
IDGLTVGGTA
ECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]