Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 74316494

GI number: 74316494

Start: 498656

End: 499564

Strand: Direct

Name: prpC [H]

Synonym: Tbd_0476

Alternate gene names: 74316494

Gene position: 498656-499564 (Clockwise)

Preceding gene: 74316493

Following gene: 74316495

Centisome position: 17.14

GC content: 63.81

Gene sequence:

>909_bases
ATGAAATTCACGATCTACCAGGCTTCGCGTCAGGGCGGGCGCAAGAATAATCAAGACCGCGTCGCCTATTCCTACAGTCG
CGATGCCCTGCTGATGGTCGTGGCCGACGGCATGGGCGGACACATGCACGGCGAAATCGCGGCGCAGATCGCGGTGCAGA
CGCTGACCGAGCAGTTCCAGAAGATGGCCAAGCCCCGGCTCGGCGATCCGCTGGCCTTCCTCGCCGACACGATCACGCGC
GCGCACTACGCGATCAACGATTACGCGGTCGAGCAGGACCTGCTCGAAATCCCCCATACGACGATCGTCGCGGCGATGAT
CCAGGACAATACGGCGTACTGGGCGCACGTCGGCGATTCGCGCCTCTATCTCTTCAGCGACGGCGACCTGATCGCGCGCA
CCGAGGATCACACCGCGGTCGCCCAGCTCGTGCGCGACGGCATCATTAGCGAGGAAGAGGCCGGCCATCACCCCGAACGC
AACAAGGTGTCGAATTGCCTGGGCGGCTACATGACGCCGCAGGTCGAATGCAACGCGCCGATCCCGCTGCACGACGCCGA
CACCATGCTGATCTGCACCGACGGCATATGGGGCATGATCAGCATTCCCGAAATCTCGGCGCTGCTGCATGCGTACACGC
TCGAAGACGCGGTGCGCCACCTGATGGACCACGCGGAATTCCGTGGCGGCGAGCACGGCGACAACCTGAGTCTGATCGCG
ATGACCTGGGGCGAGGCGCGCCTGCCGAGCAAGGATTCAATCTCGACGCTGGCCTTGCCTGACGGCGGGGTCACGACGCA
AATCAATGCCCTGCGTCCCTTGCCCGGTGCCGCGGTCGTCTCCGACGACGAGATCGAGCGCGCGATCGCCGAGATCCAGC
AGGCGATCCAGAAAATCTCCGGCAAATAG

Upstream 100 bases:

>100_bases
AAGGTGCTGATGGACCGCAGCGCGATGATGCCGCCGCGCTCGTCCCTGCTTTCCAGCCTCAGGCGCCAGTTGAACCGCGA
ATTGTTCTAAAGTATCGGCC

Downstream 100 bases:

>100_bases
CACGCGCTGGGCCGCGATCTGGCGGCCTCGCCGCGCGGTAGAATCGGTGCTTTCGTTTCCGATTTCCGCCCCATGTCCGA
ATTGACCGCCCGCCCCAGCG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKFTIYQASRQGGRKNNQDRVAYSYSRDALLMVVADGMGGHMHGEIAAQIAVQTLTEQFQKMAKPRLGDPLAFLADTITR
AHYAINDYAVEQDLLEIPHTTIVAAMIQDNTAYWAHVGDSRLYLFSDGDLIARTEDHTAVAQLVRDGIISEEEAGHHPER
NKVSNCLGGYMTPQVECNAPIPLHDADTMLICTDGIWGMISIPEISALLHAYTLEDAVRHLMDHAEFRGGEHGDNLSLIA
MTWGEARLPSKDSISTLALPDGGVTTQINALRPLPGAAVVSDDEIERAIAEIQQAIQKISGK

Sequences:

>Translated_302_residues
MKFTIYQASRQGGRKNNQDRVAYSYSRDALLMVVADGMGGHMHGEIAAQIAVQTLTEQFQKMAKPRLGDPLAFLADTITR
AHYAINDYAVEQDLLEIPHTTIVAAMIQDNTAYWAHVGDSRLYLFSDGDLIARTEDHTAVAQLVRDGIISEEEAGHHPER
NKVSNCLGGYMTPQVECNAPIPLHDADTMLICTDGIWGMISIPEISALLHAYTLEDAVRHLMDHAEFRGGEHGDNLSLIA
MTWGEARLPSKDSISTLALPDGGVTTQINALRPLPGAAVVSDDEIERAIAEIQQAIQKISGK
>Mature_302_residues
MKFTIYQASRQGGRKNNQDRVAYSYSRDALLMVVADGMGGHMHGEIAAQIAVQTLTEQFQKMAKPRLGDPLAFLADTITR
AHYAINDYAVEQDLLEIPHTTIVAAMIQDNTAYWAHVGDSRLYLFSDGDLIARTEDHTAVAQLVRDGIISEEEAGHHPER
NKVSNCLGGYMTPQVECNAPIPLHDADTMLICTDGIWGMISIPEISALLHAYTLEDAVRHLMDHAEFRGGEHGDNLSLIA
MTWGEARLPSKDSISTLALPDGGVTTQINALRPLPGAAVVSDDEIERAIAEIQQAIQKISGK

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 33026; Mature: 33026

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTIYQASRQGGRKNNQDRVAYSYSRDALLMVVADGMGGHMHGEIAAQIAVQTLTEQFQ
CEEEEEECHHCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
KMAKPRLGDPLAFLADTITRAHYAINDYAVEQDLLEIPHTTIVAAMIQDNTAYWAHVGDS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCEEEEEECCC
RLYLFSDGDLIARTEDHTAVAQLVRDGIISEEEAGHHPERNKVSNCLGGYMTPQVECNAP
EEEEEECCCEEEECCCHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHCCCCCCCEECCCC
IPLHDADTMLICTDGIWGMISIPEISALLHAYTLEDAVRHLMDHAEFRGGEHGDNLSLIA
CCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
MTWGEARLPSKDSISTLALPDGGVTTQINALRPLPGAAVVSDDEIERAIAEIQQAIQKIS
EECCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHC
GK
CC
>Mature Secondary Structure
MKFTIYQASRQGGRKNNQDRVAYSYSRDALLMVVADGMGGHMHGEIAAQIAVQTLTEQFQ
CEEEEEECHHCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
KMAKPRLGDPLAFLADTITRAHYAINDYAVEQDLLEIPHTTIVAAMIQDNTAYWAHVGDS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCEEEEEECCC
RLYLFSDGDLIARTEDHTAVAQLVRDGIISEEEAGHHPERNKVSNCLGGYMTPQVECNAP
EEEEEECCCEEEECCCHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHCCCCCCCEECCCC
IPLHDADTMLICTDGIWGMISIPEISALLHAYTLEDAVRHLMDHAEFRGGEHGDNLSLIA
CCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
MTWGEARLPSKDSISTLALPDGGVTTQINALRPLPGAAVVSDDEIERAIAEIQQAIQKIS
EECCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHC
GK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]