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The map label for this gene is ubiC

Identifier: 74316482

GI number: 74316482

Start: 486943

End: 487506

Strand: Reverse

Name: ubiC

Synonym: Tbd_0464

Alternate gene names: 74316482

Gene position: 487506-486943 (Counterclockwise)

Preceding gene: 74316487

Following gene: 74316481

Centisome position: 16.75

GC content: 70.74

Gene sequence:

>564_bases
GTGATCGCCACGCGCGACGACGTTTGCCGGCAGGCCGGTCTGCAGTATGGCTGGCTGCCCCATGCCTTCCAGGCGCCGCG
GACGCTGCGCGGCTGGCTGTCCGATCGCGGTTCGCTCACCCAGCGCCTGCGGTCCCGTTACCGTGATTTCCGCGTGCTTC
CGGTGCTGCGCGGCGTCGCGGCGCCTTTTCCCGACGAAAGCGGCGCGCTCGGCCTCGCGCGCGATGCAAGCGCCTACGTG
CGCGACGTCCTGCTCCTCGGCGATGGCAAGGCCCGCGTTTTCGCGCACAGCGTGCTGCCGCGCGCGGCCTTGCGCGGCGG
ATGGAACGGCATCGCCCGGCTCGGCACGAGACCGCTCGGCGAAGCACTGTTTCGCACCCCCCGTGTCCGCCGTCTGGCCA
TGACGATGCGCCGGGTCGACGCGCGGCACCCGCTTTATTGCGCCGCGCGCCGCCATGCCGAGGTCGCCGAGCGCGCACTG
TGGGCGCGGCGCTCGGTATTTTGCCTGGACGGCCACCCACTGCTGGTCAGTGAAGTCTTTTTGCCCGCCCTATTAACGCC
ATGA

Upstream 100 bases:

>100_bases
ATCAGGTCTCCTCCTGGTCGCGTAATGGCGGGCACCATGCTAGCACCGCCCGGGGACGGCGTCGTCTTTGGCATAATGCG
CGTTTTGCCCTGGATTCGCA

Downstream 100 bases:

>100_bases
CACTTACCGAGCGTCTCTCGCTTTACGAAAAACTGGCGCGGCTGGACAAGCCGATCGGCATCCTGCTCCTGCTCTGGCCG
ACGCTGTGGGCGCAATGGCT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIATRDDVCRQAGLQYGWLPHAFQAPRTLRGWLSDRGSLTQRLRSRYRDFRVLPVLRGVAAPFPDESGALGLARDASAYV
RDVLLLGDGKARVFAHSVLPRAALRGGWNGIARLGTRPLGEALFRTPRVRRLAMTMRRVDARHPLYCAARRHAEVAERAL
WARRSVFCLDGHPLLVSEVFLPALLTP

Sequences:

>Translated_187_residues
MIATRDDVCRQAGLQYGWLPHAFQAPRTLRGWLSDRGSLTQRLRSRYRDFRVLPVLRGVAAPFPDESGALGLARDASAYV
RDVLLLGDGKARVFAHSVLPRAALRGGWNGIARLGTRPLGEALFRTPRVRRLAMTMRRVDARHPLYCAARRHAEVAERAL
WARRSVFCLDGHPLLVSEVFLPALLTP
>Mature_187_residues
MIATRDDVCRQAGLQYGWLPHAFQAPRTLRGWLSDRGSLTQRLRSRYRDFRVLPVLRGVAAPFPDESGALGLARDASAYV
RDVLLLGDGKARVFAHSVLPRAALRGGWNGIARLGTRPLGEALFRTPRVRRLAMTMRRVDARHPLYCAARRHAEVAERAL
WARRSVFCLDGHPLLVSEVFLPALLTP

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_THIDA (Q3SLJ3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314222.1
- ProteinModelPortal:   Q3SLJ3
- SMR:   Q3SLJ3
- STRING:   Q3SLJ3
- GeneID:   3673097
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0464
- NMPDR:   fig|292415.3.peg.25
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   GTPYVAA
- BioCyc:   TDEN292415:TBD_0464-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20944; Mature: 20944

Theoretical pI: Translated: 11.99; Mature: 11.99

Prosite motif: NA

Important sites: BINDING 81-81 BINDING 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATRDDVCRQAGLQYGWLPHAFQAPRTLRGWLSDRGSLTQRLRSRYRDFRVLPVLRGVA
CCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHC
APFPDESGALGLARDASAYVRDVLLLGDGKARVFAHSVLPRAALRGGWNGIARLGTRPLG
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHH
EALFRTPRVRRLAMTMRRVDARHPLYCAARRHAEVAERALWARRSVFCLDGHPLLVSEVF
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
LPALLTP
HHHHCCC
>Mature Secondary Structure
MIATRDDVCRQAGLQYGWLPHAFQAPRTLRGWLSDRGSLTQRLRSRYRDFRVLPVLRGVA
CCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHC
APFPDESGALGLARDASAYVRDVLLLGDGKARVFAHSVLPRAALRGGWNGIARLGTRPLG
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHH
EALFRTPRVRRLAMTMRRVDARHPLYCAARRHAEVAERALWARRSVFCLDGHPLLVSEVF
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
LPALLTP
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA