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The map label for this gene is nusG [H]

Identifier: 74316411

GI number: 74316411

Start: 421199

End: 421762

Strand: Direct

Name: nusG [H]

Synonym: Tbd_0393

Alternate gene names: 74316411

Gene position: 421199-421762 (Clockwise)

Preceding gene: 74316410

Following gene: 74316412

Centisome position: 14.48

GC content: 61.7

Gene sequence:

>564_bases
ATGCGGTGGTACGTGGTTCATGCCTACTCCGGCTTCGAGAAAAGCGTGGCGCGCGCGCTGGAAGAGCGGATCGAGCGCGC
CGGGATGCGCGACCGTTTCGGCGTCATCGTCGATGAAAAAACCGGCAAGCCGCGCCCCGCGATCATGGTGCCAGTCGAGG
AAGTCGTCGAGATGAGGGCGGGACAGAAAAAGACCGCCGAGCGCAAGTTCTTCCCGGGTTACGTCCTCGTGCAGATGGAG
ATGGACGACGACACCTGGCACCTGGTCAAGAGCACGCCCAAAGTCACCGGTTTCGTCGGCGGCACGGCAACCAAGCCGGC
GCCGATCTCGGAAAAGGAAGTCCAGGCGATTCTCGACCAGATGCGCGAAGGCGTCGAGAAGCCCAAGCCCAAGGTGTTGT
TCGAGGTCGGCGAGCAGGTCCGCGTCATCGACGGGCCGTTCACCGATTTCAACGGCAACGTCGAGGAAGTGAATTACGAC
AAGAGCAAGCTACGCGTGTCGGTCATGATTTTCGGCCGGGCGACGCCCGTCGAACTGGGTTTCGGCCAGGTCGAAAAGAG
CTGA

Upstream 100 bases:

>100_bases
TCGTCATGGCATTTGTCGTCGTGATGGCGCTCTTTCTCTGGGCGGTGGATGGCGTTTTGTTATGGCTGGTGAAACTGGCC
ATGGGACAGGGGAGTTGAGT

Downstream 100 bases:

>100_bases
CCCGGAAGGGGTCGGCGGAAATCCGGTTCGCCGGAGAGGAGCGCGAGTAGGGCGACCGAAAGCGCGTTGGTACTCACGTT
AAGGAGCCATCATGGCAAAG

Product: transcription antitermination protein nusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRWYVVHAYSGFEKSVARALEERIERAGMRDRFGVIVDEKTGKPRPAIMVPVEEVVEMRAGQKKTAERKFFPGYVLVQME
MDDDTWHLVKSTPKVTGFVGGTATKPAPISEKEVQAILDQMREGVEKPKPKVLFEVGEQVRVIDGPFTDFNGNVEEVNYD
KSKLRVSVMIFGRATPVELGFGQVEKS

Sequences:

>Translated_187_residues
MRWYVVHAYSGFEKSVARALEERIERAGMRDRFGVIVDEKTGKPRPAIMVPVEEVVEMRAGQKKTAERKFFPGYVLVQME
MDDDTWHLVKSTPKVTGFVGGTATKPAPISEKEVQAILDQMREGVEKPKPKVLFEVGEQVRVIDGPFTDFNGNVEEVNYD
KSKLRVSVMIFGRATPVELGFGQVEKS
>Mature_187_residues
MRWYVVHAYSGFEKSVARALEERIERAGMRDRFGVIVDEKTGKPRPAIMVPVEEVVEMRAGQKKTAERKFFPGYVLVQME
MDDDTWHLVKSTPKVTGFVGGTATKPAPISEKEVQAILDQMREGVEKPKPKVLFEVGEQVRVIDGPFTDFNGNVEEVNYD
KSKLRVSVMIFGRATPVELGFGQVEKS

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=186, Percent_Identity=60.752688172043, Blast_Score=230, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 21094; Mature: 21094

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWYVVHAYSGFEKSVARALEERIERAGMRDRFGVIVDEKTGKPRPAIMVPVEEVVEMRA
CEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHC
GQKKTAERKFFPGYVLVQMEMDDDTWHLVKSTPKVTGFVGGTATKPAPISEKEVQAILDQ
CCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
MREGVEKPKPKVLFEVGEQVRVIDGPFTDFNGNVEEVNYDKSKLRVSVMIFGRATPVELG
HHHHHCCCCCCEEEECCCEEEEEECCCCCCCCCCEEECCCHHHEEEEEEEEECCCCEECC
FGQVEKS
CCCCCCC
>Mature Secondary Structure
MRWYVVHAYSGFEKSVARALEERIERAGMRDRFGVIVDEKTGKPRPAIMVPVEEVVEMRA
CEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHC
GQKKTAERKFFPGYVLVQMEMDDDTWHLVKSTPKVTGFVGGTATKPAPISEKEVQAILDQ
CCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
MREGVEKPKPKVLFEVGEQVRVIDGPFTDFNGNVEEVNYDKSKLRVSVMIFGRATPVELG
HHHHHCCCCCCEEEECCCEEEEEECCCCCCCCCCEEECCCHHHEEEEEEEEECCCCEECC
FGQVEKS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]