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The map label for this gene is wecB [H]

Identifier: 74316304

GI number: 74316304

Start: 303976

End: 305091

Strand: Direct

Name: wecB [H]

Synonym: Tbd_0286

Alternate gene names: 74316304

Gene position: 303976-305091 (Clockwise)

Preceding gene: 74316303

Following gene: 74316305

Centisome position: 10.45

GC content: 68.01

Gene sequence:

>1116_bases
ATGACCCAGATTCTGTGCGTCGCGGGCGCCCGCCCCAATTTCATGAAAATCGCGCCGGTCATGGCGGCGCTCGCCGAAGC
CGGCATCGCCGCGCAGTTGCTCCATACTGGCCAGCACTACGACGCGGCCATGAGTGAGGGCTTCTTCGCCGACCTCGGCA
TTCCGCAGCCCGACCATCATCTCGAAGTCGGCTCGGGCAGCCACGCCGTGCAGACGGCCGAGGTCATGAAGCGCTTCGAA
CCCGTGCTTGAACGCGTCCAGCCGCAGGCCGTGCTGGTCGTCGGCGACGTCAACTCGACGCTGGCCTGCGCGCTCGTCGC
GGCCAAGCGCGGCGTGCGCGTGATTCACGTCGAAGCGGGCCTGCGCAGCTACGATCGGGCCATGCCCGAGGAAATCAACC
GCGTGCTGACCGACCAGATTTCGGACCTGCTGTTCACGACCGAGAAGAGCGCGCTCGCGAATCTGCAGCGCGAGGGGATC
GACGCCGCGCGCGTCGAATTCGTCGGCAACGTCATGATCGATACGCTGTACCGCAACCTCGAACGTGCGGTGCCCGCGTC
GGGCACGCTCGGCGCGCCGCTCGCGGACTACGCCGTCCTGACCCTGCACCGACCGTCCAACGTCGATCACGCGGCGACAC
TCGCGGCCTTGCTCGACGTCGTCGCCGAGATCAATCGCACGCTGCCGGTGGTCGTCCCGCTGCATCCGCGCACGCGCGGC
AGCATCGAGAAATTCGGCTTCACCTCGAAGCTCGACGGGCTCCGGGTCCTGCCGCCGCTCGGCTACCTGGAGATGCTCGG
GCTCATGCGCGAAGCGAAACTCGTGTTGACCGATTCGGGCGGCATCCAGGAAGAAACGACCGCGCTCGGCGTCCCCTGTT
TGACGCTGCGCACGAGCACCGAGCGGCCGATCACGATAGACGAGGGCACCAATACGCTCGTCGGACCCGATCCCGCCGCG
ATTCGCGCCGCCTTCGCCGACGTGATCGCGGGACGTGGCAAGGCCGGCCGCATTCCCGAGTACTGGGACGGCCGCGCTGC
GAGGCGCATCGCGCACCATCTGCAGGGCTGGCTGCCGCAGCAGAAAGGCGTGCGCGCGGGGGGTGTCGGCCGATGA

Upstream 100 bases:

>100_bases
GTGCGCAAGATCCTCTACACCGTGAGCGAGCGCGAGGCGGCGAACGACGACACGCCGCCGGGCCCGCACGACCCCGCGCG
CTGAAGGGCGTGATCCCCCA

Downstream 100 bases:

>100_bases
AGAACGCCCTGTCGGTCGACGTCGAGGATTACTTTCAGGTATCGGCGTTCGCGCCGCACATTCCGCGCGAGCAATGGAAC
ACGCTGCCGTGCCGAGTCGA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTQILCVAGARPNFMKIAPVMAALAEAGIAAQLLHTGQHYDAAMSEGFFADLGIPQPDHHLEVGSGSHAVQTAEVMKRFE
PVLERVQPQAVLVVGDVNSTLACALVAAKRGVRVIHVEAGLRSYDRAMPEEINRVLTDQISDLLFTTEKSALANLQREGI
DAARVEFVGNVMIDTLYRNLERAVPASGTLGAPLADYAVLTLHRPSNVDHAATLAALLDVVAEINRTLPVVVPLHPRTRG
SIEKFGFTSKLDGLRVLPPLGYLEMLGLMREAKLVLTDSGGIQEETTALGVPCLTLRTSTERPITIDEGTNTLVGPDPAA
IRAAFADVIAGRGKAGRIPEYWDGRAARRIAHHLQGWLPQQKGVRAGGVGR

Sequences:

>Translated_371_residues
MTQILCVAGARPNFMKIAPVMAALAEAGIAAQLLHTGQHYDAAMSEGFFADLGIPQPDHHLEVGSGSHAVQTAEVMKRFE
PVLERVQPQAVLVVGDVNSTLACALVAAKRGVRVIHVEAGLRSYDRAMPEEINRVLTDQISDLLFTTEKSALANLQREGI
DAARVEFVGNVMIDTLYRNLERAVPASGTLGAPLADYAVLTLHRPSNVDHAATLAALLDVVAEINRTLPVVVPLHPRTRG
SIEKFGFTSKLDGLRVLPPLGYLEMLGLMREAKLVLTDSGGIQEETTALGVPCLTLRTSTERPITIDEGTNTLVGPDPAA
IRAAFADVIAGRGKAGRIPEYWDGRAARRIAHHLQGWLPQQKGVRAGGVGR
>Mature_370_residues
TQILCVAGARPNFMKIAPVMAALAEAGIAAQLLHTGQHYDAAMSEGFFADLGIPQPDHHLEVGSGSHAVQTAEVMKRFEP
VLERVQPQAVLVVGDVNSTLACALVAAKRGVRVIHVEAGLRSYDRAMPEEINRVLTDQISDLLFTTEKSALANLQREGID
AARVEFVGNVMIDTLYRNLERAVPASGTLGAPLADYAVLTLHRPSNVDHAATLAALLDVVAEINRTLPVVVPLHPRTRGS
IEKFGFTSKLDGLRVLPPLGYLEMLGLMREAKLVLTDSGGIQEETTALGVPCLTLRTSTERPITIDEGTNTLVGPDPAAI
RAAFADVIAGRGKAGRIPEYWDGRAARRIAHHLQGWLPQQKGVRAGGVGR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=377, Percent_Identity=31.2997347480106, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 39776; Mature: 39645

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQILCVAGARPNFMKIAPVMAALAEAGIAAQLLHTGQHYDAAMSEGFFADLGIPQPDHH
CCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCC
LEVGSGSHAVQTAEVMKRFEPVLERVQPQAVLVVGDVNSTLACALVAAKRGVRVIHVEAG
EECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCC
LRSYDRAMPEEINRVLTDQISDLLFTTEKSALANLQREGIDAARVEFVGNVMIDTLYRNL
HHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERAVPASGTLGAPLADYAVLTLHRPSNVDHAATLAALLDVVAEINRTLPVVVPLHPRTRG
HHHCCCCCCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SIEKFGFTSKLDGLRVLPPLGYLEMLGLMREAKLVLTDSGGIQEETTALGVPCLTLRTST
CHHHCCCCCCCCCEEECCCCCHHHHHHHHHHCEEEEECCCCCCCHHHHHCCCEEEEECCC
ERPITIDEGTNTLVGPDPAAIRAAFADVIAGRGKAGRIPEYWDGRAARRIAHHLQGWLPQ
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
QKGVRAGGVGR
HCCCCCCCCCC
>Mature Secondary Structure 
TQILCVAGARPNFMKIAPVMAALAEAGIAAQLLHTGQHYDAAMSEGFFADLGIPQPDHH
CEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHCCCEEECCCCCCCCC
LEVGSGSHAVQTAEVMKRFEPVLERVQPQAVLVVGDVNSTLACALVAAKRGVRVIHVEAG
EECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCC
LRSYDRAMPEEINRVLTDQISDLLFTTEKSALANLQREGIDAARVEFVGNVMIDTLYRNL
HHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ERAVPASGTLGAPLADYAVLTLHRPSNVDHAATLAALLDVVAEINRTLPVVVPLHPRTRG
HHHCCCCCCCCCCHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SIEKFGFTSKLDGLRVLPPLGYLEMLGLMREAKLVLTDSGGIQEETTALGVPCLTLRTST
CHHHCCCCCCCCCEEECCCCCHHHHHHHHHHCEEEEECCCCCCCHHHHHCCCEEEEECCC
ERPITIDEGTNTLVGPDPAAIRAAFADVIAGRGKAGRIPEYWDGRAARRIAHHLQGWLPQ
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
QKGVRAGGVGR
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA