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The map label for this gene is argJ

Identifier: 74316047

GI number: 74316047

Start: 29347

End: 30570

Strand: Reverse

Name: argJ

Synonym: Tbd_0029

Alternate gene names: 74316047

Gene position: 30570-29347 (Counterclockwise)

Preceding gene: 74316048

Following gene: 74316046

Centisome position: 1.05

GC content: 68.63

Gene sequence:

>1224_bases
ATGCCCGTCAATCTTGTCGCACCCGACCCCGCCTCGCTTTTGCCGGTTCCCGGCGTCCGTCTGGGCATCGCCTCAGCCGG
CATCAAGAAAGCGGGCAGACGCGACCTCACCCTGATCGAACTCGCGCCAGGCAGCCGCGTCGCTGGGGTCTTCACGCAGA
ATCGTTTCTGCGCCGCGCCGGTCACCGTGTGTCGCGAACATCTGACGCGCGGCGACGTCCGCGCGCTCGTGATCAATACC
GGGAACGCCAACGCGGGTACGGGCGACGAAGGCCTCGACCGCGCGCGCCGGACCTGTTCCGCGGTCGCCGATCTGTTCGC
CGTCGACGCCACCCAGGTCCTGCCATTTTCGACCGGCGTGATCCTCGAGCCGCTGCCGATCGACAAGATCCTGCCAGCGC
TGCCGGCGGCGCACGCCGACCTCGCGGCCGGGCACTGGAGCGAAGCTGCCGCCGCGATCATGACGACCGACATCGTCGCC
AAGGGCGCATCGCGGCAACTGCAGATCGACGGCAGGACGATCACGGTCACCGGCATCGCGAAGGGCTCCGGCATGATCCA
CCCCAATATGGCGACCATGCTCGGCTTCGTCGCCACCGACGCCGCGATCGCACCCGCCCTCATGCAACGCATGGTGCGTG
ACGTTGCGGACGTTTCGTTCAACTGCGTCACGGTCGACGGCGACACCTCGACCAACGACAGCTTCATCCTGATCGCCACC
GGACAGGCGGGCAACGCCGAGATCGCCGACGCAGGGACCGACTATTCCGCGCTCAAGGCGGCGCTCGCCGACGTCGCGAT
CGAGCTCGCGCAGGCGATGGCGCGCGACGGCGAGGGGGCGACGAAGTTCATGACCATCGCCGTCGAAGGCGGGCGCGACC
GGGCGGAGTGCAAGCAGATCGCCTACGCGATCGCGCGATCGCCGCTCGTCAAGACCGCGTTCTTCGCGAGCGACCCGAAC
CTCGGCCGCATCCTCGCCGCGATCGGCTACGCCGGCGTCCAGGACCTCGACGTCAACGCGCTCAAAGTGTGGCTCGGCGA
CGTCCTCGTCGCCGAAGCGGGCGGCCGTGCCGCAGGCTACAGCGAAGCCGCGGCGGCGGCGGTCATGAAGGCGGCCGAGA
TCACCGTCCGCGTATCGCTCGCGCGCGGCGACGCCCGCGCCACCGTGTGGACCTGCGACTTCTCGTACGACTACGTGAAG
ATCAACGCGGAATATCGCACCTGA

Upstream 100 bases:

>100_bases
GAGTTTCGCCGCGCCCTGAACTGGCTGCTCGGCCGCACACCTTGAAGCCGGGCGCCAGCCGCCCGCATAAAATAGCGGTT
TTGCCTCCCGGTACGCCGCC

Downstream 100 bases:

>100_bases
GCGTGCAGCCGGCTCCCTTCCGGCACGGCGCGCGCGGCATGCCGCACATCGAAAGCCGATTTTTTCGCCGAGCGGACGCT
AGAATTTCGGGATGACCGAT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MPVNLVAPDPASLLPVPGVRLGIASAGIKKAGRRDLTLIELAPGSRVAGVFTQNRFCAAPVTVCREHLTRGDVRALVINT
GNANAGTGDEGLDRARRTCSAVADLFAVDATQVLPFSTGVILEPLPIDKILPALPAAHADLAAGHWSEAAAAIMTTDIVA
KGASRQLQIDGRTITVTGIAKGSGMIHPNMATMLGFVATDAAIAPALMQRMVRDVADVSFNCVTVDGDTSTNDSFILIAT
GQAGNAEIADAGTDYSALKAALADVAIELAQAMARDGEGATKFMTIAVEGGRDRAECKQIAYAIARSPLVKTAFFASDPN
LGRILAAIGYAGVQDLDVNALKVWLGDVLVAEAGGRAAGYSEAAAAAVMKAAEITVRVSLARGDARATVWTCDFSYDYVK
INAEYRT

Sequences:

>Translated_407_residues
MPVNLVAPDPASLLPVPGVRLGIASAGIKKAGRRDLTLIELAPGSRVAGVFTQNRFCAAPVTVCREHLTRGDVRALVINT
GNANAGTGDEGLDRARRTCSAVADLFAVDATQVLPFSTGVILEPLPIDKILPALPAAHADLAAGHWSEAAAAIMTTDIVA
KGASRQLQIDGRTITVTGIAKGSGMIHPNMATMLGFVATDAAIAPALMQRMVRDVADVSFNCVTVDGDTSTNDSFILIAT
GQAGNAEIADAGTDYSALKAALADVAIELAQAMARDGEGATKFMTIAVEGGRDRAECKQIAYAIARSPLVKTAFFASDPN
LGRILAAIGYAGVQDLDVNALKVWLGDVLVAEAGGRAAGYSEAAAAAVMKAAEITVRVSLARGDARATVWTCDFSYDYVK
INAEYRT
>Mature_406_residues
PVNLVAPDPASLLPVPGVRLGIASAGIKKAGRRDLTLIELAPGSRVAGVFTQNRFCAAPVTVCREHLTRGDVRALVINTG
NANAGTGDEGLDRARRTCSAVADLFAVDATQVLPFSTGVILEPLPIDKILPALPAAHADLAAGHWSEAAAAIMTTDIVAK
GASRQLQIDGRTITVTGIAKGSGMIHPNMATMLGFVATDAAIAPALMQRMVRDVADVSFNCVTVDGDTSTNDSFILIATG
QAGNAEIADAGTDYSALKAALADVAIELAQAMARDGEGATKFMTIAVEGGRDRAECKQIAYAIARSPLVKTAFFASDPNL
GRILAAIGYAGVQDLDVNALKVWLGDVLVAEAGGRAAGYSEAAAAAVMKAAEITVRVSLARGDARATVWTCDFSYDYVKI
NAEYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=412, Percent_Identity=38.1067961165049, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_THIDA (Q3SMQ9)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_313787.1
- ProteinModelPortal:   Q3SMQ9
- SMR:   Q3SMQ9
- STRING:   Q3SMQ9
- MEROPS:   T05.001
- GeneID:   3671990
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0029
- NMPDR:   fig|292415.3.peg.750
- eggNOG:   COG1364
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- PhylomeDB:   Q3SMQ9
- ProtClustDB:   PRK05388
- BioCyc:   TDEN292415:TBD_0029-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42183; Mature: 42051

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNLVAPDPASLLPVPGVRLGIASAGIKKAGRRDLTLIELAPGSRVAGVFTQNRFCAAP
CCCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCEECCH
VTVCREHLTRGDVRALVINTGNANAGTGDEGLDRARRTCSAVADLFAVDATQVLPFSTGV
HHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCC
ILEPLPIDKILPALPAAHADLAAGHWSEAAAAIMTTDIVAKGASRQLQIDGRTITVTGIA
EECCCCHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEE
KGSGMIHPNMATMLGFVATDAAIAPALMQRMVRDVADVSFNCVTVDGDTSTNDSFILIAT
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEE
GQAGNAEIADAGTDYSALKAALADVAIELAQAMARDGEGATKFMTIAVEGGRDRAECKQI
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AYAIARSPLVKTAFFASDPNLGRILAAIGYAGVQDLDVNALKVWLGDVLVAEAGGRAAGY
HHHHHCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEECCCCCCCCC
SEAAAAAVMKAAEITVRVSLARGDARATVWTCDFSYDYVKINAEYRT
HHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEECCEEEEEEEEEECC
>Mature Secondary Structure 
PVNLVAPDPASLLPVPGVRLGIASAGIKKAGRRDLTLIELAPGSRVAGVFTQNRFCAAP
CCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCEECCH
VTVCREHLTRGDVRALVINTGNANAGTGDEGLDRARRTCSAVADLFAVDATQVLPFSTGV
HHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCC
ILEPLPIDKILPALPAAHADLAAGHWSEAAAAIMTTDIVAKGASRQLQIDGRTITVTGIA
EECCCCHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEE
KGSGMIHPNMATMLGFVATDAAIAPALMQRMVRDVADVSFNCVTVDGDTSTNDSFILIAT
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEE
GQAGNAEIADAGTDYSALKAALADVAIELAQAMARDGEGATKFMTIAVEGGRDRAECKQI
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AYAIARSPLVKTAFFASDPNLGRILAAIGYAGVQDLDVNALKVWLGDVLVAEAGGRAAGY
HHHHHCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEECCCCCCCCC
SEAAAAAVMKAAEITVRVSLARGDARATVWTCDFSYDYVKINAEYRT
HHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEECCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA