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The map label for this gene is yafC [H]

Identifier: 73543095

GI number: 73543095

Start: 3745764

End: 3746675

Strand: Reverse

Name: yafC [H]

Synonym: Reut_A3413

Alternate gene names: 73543095

Gene position: 3746675-3745764 (Counterclockwise)

Preceding gene: 73543097

Following gene: 73543090

Centisome position: 98.43

GC content: 64.58

Gene sequence:

>912_bases
ATGGATCGCCTGCAATCGATGCGCGTGTTCGCCAAAGTTGTGGAACTCGGCAGCTTCGCGCGTGCAGCGCAGCAGTTGGA
AATGTCCAATGCGGTGGTGACACGTTATGTCGCGGACCTGGAGAGTCACCTGGGCACGCGGCTCCTGAACCGCACGACGC
GCAGCCTTTCCCTGACCGACGCCGGCGAAACCTACCTGCAGCGCTGCCAGCAGATCCTTGAAGACGTGGAGGAGGCCGAG
GGCGTCGTGACAGCCCGCAGCCAGTCGTTATCCGGCACGTTGCGACTGGTGACACCGGTGATGTTCGGCCTGCACCTGTT
GCCGAACCTGATGTCGCGCTTCCAGCAGCTATACCCTGACGTGGTGTTTGACGTGCTCCTGTCCGACCGGAACGTGGACA
TCGTCGAAGAGGGCCGGGACGTCGCCGTCATGCTGTCGGACCTGGGCCTCGGTTCGCACCTGGTCGCCCGTCCGCTGATC
TCGGCGGAGATCGTGCTGTGCGCCTCGCCGGAATATGTCCGCACGCACGCACCATTGCGCCACGCGCACGAGCTGACCAG
CCATCGCTGCATCGCGATGCGCCTGCCGAACGTGGAACACGAATGGACGCTGCTGGGCCCGGAGGGCGAAGTGACCGTGC
CGATCCGCCCCGGACTGCTGTGCAGCAACGCCGAACTGGCGCACCAGGCCGCACTAGCCAATATGGGCGTGGCGATGCTG
TCGTCGTACCTGGCCCGGCAAAACATCGAGGCCGGCAACCTCGTGCGTGTGCTGCCGCAGTACCAGCTGCCGCGGCGCGA
TGTCAGCGTGGTCTACCCGAGCCGCAAGTTCCTGCCGACCAAGGTCCGCGCGTTCATTGACTTTCTGCTGGAAGAAGGCC
AGGTCAGAGGCCGGGACGAGCAGTTTTCCTGA

Upstream 100 bases:

>100_bases
CATATCAATAAATATCGGTTGCCACAATGATTAGTTCTGATTCCAACAATAAAGTCGCCTGAACCGGGAAAAATTCAGGG
AAACGACGGGAGACTGTGTC

Downstream 100 bases:

>100_bases
GCGGGCGGGTAGCCGCAGCTGAAACGCCGCCGCGCCCGCACCGCCTCGCCGCTTATTCCTCGGCTTCGACCGTCGCCTTG
CCCGCGGCGCGGGTCTTCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDRLQSMRVFAKVVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCQQILEDVEEAE
GVVTARSQSLSGTLRLVTPVMFGLHLLPNLMSRFQQLYPDVVFDVLLSDRNVDIVEEGRDVAVMLSDLGLGSHLVARPLI
SAEIVLCASPEYVRTHAPLRHAHELTSHRCIAMRLPNVEHEWTLLGPEGEVTVPIRPGLLCSNAELAHQAALANMGVAML
SSYLARQNIEAGNLVRVLPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEEGQVRGRDEQFS

Sequences:

>Translated_303_residues
MDRLQSMRVFAKVVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCQQILEDVEEAE
GVVTARSQSLSGTLRLVTPVMFGLHLLPNLMSRFQQLYPDVVFDVLLSDRNVDIVEEGRDVAVMLSDLGLGSHLVARPLI
SAEIVLCASPEYVRTHAPLRHAHELTSHRCIAMRLPNVEHEWTLLGPEGEVTVPIRPGLLCSNAELAHQAALANMGVAML
SSYLARQNIEAGNLVRVLPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEEGQVRGRDEQFS
>Mature_303_residues
MDRLQSMRVFAKVVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTDAGETYLQRCQQILEDVEEAE
GVVTARSQSLSGTLRLVTPVMFGLHLLPNLMSRFQQLYPDVVFDVLLSDRNVDIVEEGRDVAVMLSDLGLGSHLVARPLI
SAEIVLCASPEYVRTHAPLRHAHELTSHRCIAMRLPNVEHEWTLLGPEGEVTVPIRPGLLCSNAELAHQAALANMGVAML
SSYLARQNIEAGNLVRVLPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEEGQVRGRDEQFS

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=36.2068965517241, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=32.5259515570934, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=32.5581395348837, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789639, Length=311, Percent_Identity=31.5112540192926, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=27.0903010033445, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=26.962457337884, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=27.3648648648649, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789173, Length=306, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788706, Length=302, Percent_Identity=27.8145695364238, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788748, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790011, Length=306, Percent_Identity=21.5686274509804, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786448, Length=299, Percent_Identity=25.0836120401338, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=22.8956228956229, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=29.0322580645161, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=202, Percent_Identity=25.2475247524752, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=119, Percent_Identity=35.2941176470588, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789506, Length=175, Percent_Identity=24, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786713, Length=286, Percent_Identity=24.4755244755245, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33823; Mature: 33823

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50931 HTH_LYSR ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQSMRVFAKVVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
AGETYLQRCQQILEDVEEAEGVVTARSQSLSGTLRLVTPVMFGLHLLPNLMSRFQQLYPD
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFDVLLSDRNVDIVEEGRDVAVMLSDLGLGSHLVARPLISAEIVLCASPEYVRTHAPLR
HHHHHHHCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHEEEEECCCCHHHHCCHHH
HAHELTSHRCIAMRLPNVEHEWTLLGPEGEVTVPIRPGLLCSNAELAHQAALANMGVAML
HHHHHHHCCEEEEECCCCCCCEEEECCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHH
SSYLARQNIEAGNLVRVLPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEEGQVRGRDE
HHHHHHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
QFS
CCC
>Mature Secondary Structure
MDRLQSMRVFAKVVELGSFARAAQQLEMSNAVVTRYVADLESHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCC
AGETYLQRCQQILEDVEEAEGVVTARSQSLSGTLRLVTPVMFGLHLLPNLMSRFQQLYPD
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFDVLLSDRNVDIVEEGRDVAVMLSDLGLGSHLVARPLISAEIVLCASPEYVRTHAPLR
HHHHHHHCCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHHHHEEEEECCCCHHHHCCHHH
HAHELTSHRCIAMRLPNVEHEWTLLGPEGEVTVPIRPGLLCSNAELAHQAALANMGVAML
HHHHHHHCCEEEEECCCCCCCEEEECCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHH
SSYLARQNIEAGNLVRVLPQYQLPRRDVSVVYPSRKFLPTKVRAFIDFLLEEGQVRGRDE
HHHHHHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
QFS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]