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The map label for this gene is hmrR2 [H]

Identifier: 73543057

GI number: 73543057

Start: 3695321

End: 3695770

Strand: Reverse

Name: hmrR2 [H]

Synonym: Reut_A3375

Alternate gene names: 73543057

Gene position: 3695770-3695321 (Counterclockwise)

Preceding gene: 73543058

Following gene: 73543056

Centisome position: 97.09

GC content: 67.56

Gene sequence:

>450_bases
ATGAATATCGGCGAGGCAGCGGACGCCTCTGGCGTTTCGGCGAAGATGATCCGGCACTACGAGTCCATCGGCCTGGTCGA
TGCGCCGCCGCGCACCGAAGGCGGCTACCGCCGCTACGACGAGCGCGCCGTGCATACCTTGCGCTTCGTGCGGCGCGCCC
GTAGTCTCGGGTTCTCGCTCGAGGAGATCCGCGGGCTGCTGTCGCTGTGGCATGACCGCCGGCGCGCCAGCGCAGATGTG
AAGGCGATGACGCTGCGGCATGTGGCGGACCTGGAAAAGCGGATTGCCGAACTTGCCGCGATGCGCGATACGCTGCGCGC
GCTGGCCGAGGCCTGCAGCGGCGACGACCGGCCCGATTGCCCCATCCTCGCCGACTTCGCGCAGCCCGATGACCATGCGC
ATTGCCATGGTGAGGGCGCATGTAGCGGTACGGTGGCGGACGAACAATAA

Upstream 100 bases:

>100_bases
GGGCCGCGATGGCGTTCTCGAGCGTGAGCGTCGTCAGCAACGCGTTGCTGCTGCGGCGCTGGCATCCGGGTGGCGAGACG
GGTGAAACAGGAGCAAAGGC

Downstream 100 bases:

>100_bases
TCAGAAACGCAATGCCCCCGCGCCGGTCGGGCGGCATCGGGAGGAGACCCGCGGATGGACAAGCCCATGACGGAAAACCC
CGTTCATCCTGCTGAAGCAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNIGEAADASGVSAKMIRHYESIGLVDAPPRTEGGYRRYDERAVHTLRFVRRARSLGFSLEEIRGLLSLWHDRRRASADV
KAMTLRHVADLEKRIAELAAMRDTLRALAEACSGDDRPDCPILADFAQPDDHAHCHGEGACSGTVADEQ

Sequences:

>Translated_149_residues
MNIGEAADASGVSAKMIRHYESIGLVDAPPRTEGGYRRYDERAVHTLRFVRRARSLGFSLEEIRGLLSLWHDRRRASADV
KAMTLRHVADLEKRIAELAAMRDTLRALAEACSGDDRPDCPILADFAQPDDHAHCHGEGACSGTVADEQ
>Mature_149_residues
MNIGEAADASGVSAKMIRHYESIGLVDAPPRTEGGYRRYDERAVHTLRFVRRARSLGFSLEEIRGLLSLWHDRRRASADV
KAMTLRHVADLEKRIAELAAMRDTLRALAEACSGDDRPDCPILADFAQPDDHAHCHGEGACSGTVADEQ

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=48.8188976377953, Blast_Score=129, Evalue=8e-32,
Organism=Escherichia coli, GI1789687, Length=129, Percent_Identity=39.5348837209302, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16441; Mature: 16441

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEAADASGVSAKMIRHYESIGLVDAPPRTEGGYRRYDERAVHTLRFVRRARSLGFSL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
EEIRGLLSLWHDRRRASADVKAMTLRHVADLEKRIAELAAMRDTLRALAEACSGDDRPDC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADFAQPDDHAHCHGEGACSGTVADEQ
CEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGEAADASGVSAKMIRHYESIGLVDAPPRTEGGYRRYDERAVHTLRFVRRARSLGFSL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
EEIRGLLSLWHDRRRASADVKAMTLRHVADLEKRIAELAAMRDTLRALAEACSGDDRPDC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILADFAQPDDHAHCHGEGACSGTVADEQ
CEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]