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The map label for this gene is atpA [H]

Identifier: 73543030

GI number: 73543030

Start: 3666088

End: 3667629

Strand: Reverse

Name: atpA [H]

Synonym: Reut_A3348

Alternate gene names: 73543030

Gene position: 3667629-3666088 (Counterclockwise)

Preceding gene: 73543031

Following gene: 73543029

Centisome position: 96.35

GC content: 62.97

Gene sequence:

>1542_bases
ATGCAACTGAACCCCTCAGAAATCAGCGAGCTGATCAAGTCCCGCATCTCGGGTCTTGGCGCCGACGCTGAAGTGCGCAA
CACCGGCACGGTGATTTCCGTGACCGATGGTATCTGCCGCGTGCACGGCCTGTCTGGCGTGATGCAGGGCGAGATGCTGG
AATTCCCGGGCAACACCTTCGGCCTCGCGCTGAACCTCGAGCGCGACTCCGTCGGTGCCGTGGTGCTGGGCGACTACGAA
CACATTTCGGAAGGCGATACGGTCAAGTGCACCGGCCGCATTCTGGAAGTGCCCGTTGGCAAGGAGCTGCTGGGCCGCGT
GGTCAACACGCTGGGCCAGCCGATCGATGGCAAGGGCCCGATCAACGCGAAGGAAACCGACGTGATCGAAAAGGTCGCGC
CGGGCGTGATCGCGCGTCAGTCGGTGAGCCAGCCGGTGCAGACCGGCCTGAAGTCGATCGACTCGATGGTGCCGATCGGC
CGTGGCCAGCGTGAGCTGATCATTGGCGACCGCCAGACCGGCAAGACCGCCGTGGCTGTCGACGCCATCATCAACCAGAA
GGGCAAGGGCATCTTCTGCGTGTACGTGGCAATCGGCCAGAAGGCTTCGACGATCGCCAACGTGGTGCGCAAGCTCGAAG
AACACGGCGCGATGGAATACACCGTCGTCGTGGCTGCCGCCGCTTCGGATTCGGCCGCCATGCAGTACCTGGCTGCCTAC
GCCGGCTGCACGATGGGCGAGTACTTCCGCGACCGCGGCGAAGACGCGCTGATCGTTTATGACGATCTGACCAAGCAGGC
CTGGGCCTACCGCCAGGTGTCGCTGCTGCTGCGCCGCCCGCCGGGCCGCGAAGCTTACCCCGGCGACGTGTTCTACCTGC
ACTCGCGCCTGCTGGAGCGTGCTGCCCGTGTGAACGAAGAGTACGTCGAGAACTTCACCAAGGGTGCCGTGAAGGGCAAG
ACCGGTTCGCTGACCGCACTGCCTATCATCGAAACGCAGGCTGGTGACGTGTCCGCATTCGTGCCGACCAACGTGATCTC
GATTACCGACGGTCAGATCTTCCTGGAAACCGACCTGTTCAATGCCGGTATCCGTCCCGCGATCAACGCCGGTATCTCGG
TGTCGCGCGTGGGTGGTGCTGCACAGACCAAGGTGGTGAAGAACCTGTCCGGCGGTATCCGTACCGACCTGGCCCAGTAC
CGTGAACTGGCTGCGTTCGCGCAGTTCGCTTCGGACCTGGACGACGCTACCCGCAAGCAGCTCGAGCGTGGCCGCCGCGT
GACCGAACTGCTCAAGCAGGCTCAGTACCAGCCGCAGCAAGTGTGGCAACTGGCCGCGTCGCTGTTCGCCGCCAACAATG
GCTTCCTCGACAACGTGGAAGTGAAGGACATTCTGCCGTTCGAGAAGGGCCTGCACGACCATCTGAAGACCAAGTACGCC
GACCTCGTCAACCGCATCGAAGAGACCAAGGTCCTCTCGAAGGAAGATGAACCGGCGCTGCGTGCTGCGATCGAGGATTT
CAGGAAGTCCGCCGCGTTCTAA

Upstream 100 bases:

>100_bases
TGCTCGACACCTCCGTGCGTGCGCGCCTGGCTGCCATGCAAACCGCGCTGACCGCCGTCTGATCGGCCGTCCGTCGGATT
GAAGAATTAGGAGCATTGTG

Downstream 100 bases:

>100_bases
CCGCGTGATTCCACGAAGCTCGCCGCGCCTGCGCCGGGGTCGCCCCGGCGGTGCGCGGCGAGAGTTCGAATGGAGAGGAA
GATATGGCCGGAACGAAAGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVENFTKGAVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQAQYQPQQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYA
DLVNRIEETKVLSKEDEPALRAAIEDFRKSAAF

Sequences:

>Translated_513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVENFTKGAVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQAQYQPQQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYA
DLVNRIEETKVLSKEDEPALRAAIEDFRKSAAF
>Mature_513_residues
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVENFTKGAVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELLKQAQYQPQQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYA
DLVNRIEETKVLSKEDEPALRAAIEDFRKSAAF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=56.6666666666667, Blast_Score=584, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=56.6666666666667, Blast_Score=584, Evalue=1e-167,
Organism=Homo sapiens, GI32189394, Length=485, Percent_Identity=25.1546391752577, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913428, Length=312, Percent_Identity=28.525641025641, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=313, Percent_Identity=28.7539936102236, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19913424, Length=337, Percent_Identity=25.2225519287834, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=70.7602339181287, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=433, Percent_Identity=25.635103926097, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=27.7580071174377, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.4705882352941, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.4705882352941, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.5490196078431, Blast_Score=523, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=28.7128712871287, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=382, Percent_Identity=26.4397905759162, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=471, Percent_Identity=24.416135881104, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=56, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=267, Percent_Identity=26.2172284644195, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.7729941291585, Blast_Score=570, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6322581, Length=423, Percent_Identity=26.0047281323877, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=309, Percent_Identity=29.4498381877023, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=57.4509803921569, Blast_Score=582, Evalue=1e-166,
Organism=Drosophila melanogaster, GI24638766, Length=458, Percent_Identity=25.764192139738, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=28.5245901639344, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI28574560, Length=412, Percent_Identity=25.7281553398058, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24583992, Length=330, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583988, Length=272, Percent_Identity=26.8382352941176, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583986, Length=272, Percent_Identity=26.8382352941176, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583984, Length=272, Percent_Identity=26.8382352941176, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55510; Mature: 55510

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGDYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGP
EEEEEECCCCCCEEEEECHHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQTGKTAVAV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVENFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQAQYQPQQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYA
HHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
DLVNRIEETKVLSKEDEPALRAAIEDFRKSAAF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCCCCCEECCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGDYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGP
EEEEEECCCCCCEEEEECHHHCCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQTGKTAVAV
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGAMEYTVVVAAAASDSAAMQYLAAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEEYVENFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVVKNLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQAQYQPQQVWQLAASLFAANNGFLDNVEVKDILPFEKGLHDHLKTKYA
HHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
DLVNRIEETKVLSKEDEPALRAAIEDFRKSAAF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA