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The map label for this gene is blh [H]

Identifier: 73543016

GI number: 73543016

Start: 3645569

End: 3646306

Strand: Direct

Name: blh [H]

Synonym: Reut_A3334

Alternate gene names: 73543016

Gene position: 3645569-3646306 (Clockwise)

Preceding gene: 73543015

Following gene: 73543017

Centisome position: 95.77

GC content: 65.04

Gene sequence:

>738_bases
ATGCAAACCTTCTATCAGCTGTTCGACGAAACCTCGTCGACCTTCACCTACCTGCTGATCGACGCCACCACGCGCGACGC
GATCCTGATCGATCCGGTCGACCACCAACTCGAGCGCGACATGGCCGTGCTGCGCGACGCGGGCGCCAGCCTCGCGTGGG
TGGTGGAAACCCATGCCCATGCCGACCACATCACGTCGGCAGGCCATGTCGCCATGCAGACCGGCGCAAAGACCGCTGCG
CCATCGGGATGCGACATCAAGCCGGCGCAGATGCAGCTGATCGACGGCGATACGCTCACCTTCGGCACGCAGGTACTGCG
CGCGATCCATACGCCCGGGCATACCGCCGGCAGCATGAGCTACCTGTGGGAGGAAGCCACGCCGGATGGCCCATTGCGCC
GCGTGTTCACCGGTGACGCATTGCTGATCGACGGCTGTGGCCGCACCGATTTCCAATCCGGCGATGCCGGCACGCTATAT
GACAGCCTGACGCGCAAGCTGTTCGCGTTGCCCGATGAGACCCTCGTATTTCCGGCGCACGACTACAAGGGCCGGACGTC
GTCGACCATCGGCCAGGAGCGTGCACACAACAGCCGCGTGGCCGGACGTACGCGCGATGAGTTCATCGACATGATGCGCA
ACCTGAACCTGCCGCGCCCGAAGCTGATCGATGTCGCAGTGCCGGCCAACCAGCGGCTCGGGCTGCGCGATGGCGAAAGC
GTGCCGCATGGCGCCTGA

Upstream 100 bases:

>100_bases
AATATCGTGGAGTGCTGAGGCCTTAGCGGCGTATCATGGCGCCAGTCTCCCCGGGCGCCACCTCAGGCGCCTGCAGAAAC
AGAGCAAAAAGCGAGGCGCC

Downstream 100 bases:

>100_bases
GTACAGGCGCGTCAAATCCTTCTATTCGGCGCGCCAAAAACTCTGAATTGACTTCGCGCTGACCGCTGCAATACTGATCT
CTCTGCCATATCGGGCATGC

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MQTFYQLFDETSSTFTYLLIDATTRDAILIDPVDHQLERDMAVLRDAGASLAWVVETHAHADHITSAGHVAMQTGAKTAA
PSGCDIKPAQMQLIDGDTLTFGTQVLRAIHTPGHTAGSMSYLWEEATPDGPLRRVFTGDALLIDGCGRTDFQSGDAGTLY
DSLTRKLFALPDETLVFPAHDYKGRTSSTIGQERAHNSRVAGRTRDEFIDMMRNLNLPRPKLIDVAVPANQRLGLRDGES
VPHGA

Sequences:

>Translated_245_residues
MQTFYQLFDETSSTFTYLLIDATTRDAILIDPVDHQLERDMAVLRDAGASLAWVVETHAHADHITSAGHVAMQTGAKTAA
PSGCDIKPAQMQLIDGDTLTFGTQVLRAIHTPGHTAGSMSYLWEEATPDGPLRRVFTGDALLIDGCGRTDFQSGDAGTLY
DSLTRKLFALPDETLVFPAHDYKGRTSSTIGQERAHNSRVAGRTRDEFIDMMRNLNLPRPKLIDVAVPANQRLGLRDGES
VPHGA
>Mature_245_residues
MQTFYQLFDETSSTFTYLLIDATTRDAILIDPVDHQLERDMAVLRDAGASLAWVVETHAHADHITSAGHVAMQTGAKTAA
PSGCDIKPAQMQLIDGDTLTFGTQVLRAIHTPGHTAGSMSYLWEEATPDGPLRRVFTGDALLIDGCGRTDFQSGDAGTLY
DSLTRKLFALPDETLVFPAHDYKGRTSSTIGQERAHNSRVAGRTRDEFIDMMRNLNLPRPKLIDVAVPANQRLGLRDGES
VPHGA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=231, Percent_Identity=44.1558441558442, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI14150041, Length=170, Percent_Identity=36.4705882352941, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46361987, Length=170, Percent_Identity=36.4705882352941, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI116642887, Length=221, Percent_Identity=29.8642533936652, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI21703352, Length=221, Percent_Identity=29.8642533936652, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI94538320, Length=175, Percent_Identity=33.1428571428571, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI94538322, Length=181, Percent_Identity=32.0441988950276, Blast_Score=78, Evalue=7e-15,
Organism=Escherichia coli, GI1787158, Length=200, Percent_Identity=30, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538952, Length=227, Percent_Identity=38.7665198237885, Blast_Score=169, Evalue=8e-43,
Organism=Drosophila melanogaster, GI221330176, Length=236, Percent_Identity=44.9152542372881, Blast_Score=207, Evalue=6e-54,
Organism=Drosophila melanogaster, GI21356335, Length=172, Percent_Identity=33.1395348837209, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24667703, Length=172, Percent_Identity=33.1395348837209, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24667711, Length=173, Percent_Identity=32.9479768786127, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 26733; Mature: 26733

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTFYQLFDETSSTFTYLLIDATTRDAILIDPVDHQLERDMAVLRDAGASLAWVVETHAH
CCHHHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCC
ADHITSAGHVAMQTGAKTAAPSGCDIKPAQMQLIDGDTLTFGTQVLRAIHTPGHTAGSMS
HHHHCCCCCEEEECCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCHH
YLWEEATPDGPLRRVFTGDALLIDGCGRTDFQSGDAGTLYDSLTRKLFALPDETLVFPAH
HHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
DYKGRTSSTIGQERAHNSRVAGRTRDEFIDMMRNLNLPRPKLIDVAVPANQRLGLRDGES
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
VPHGA
CCCCC
>Mature Secondary Structure
MQTFYQLFDETSSTFTYLLIDATTRDAILIDPVDHQLERDMAVLRDAGASLAWVVETHAH
CCHHHHHHHCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCC
ADHITSAGHVAMQTGAKTAAPSGCDIKPAQMQLIDGDTLTFGTQVLRAIHTPGHTAGSMS
HHHHCCCCCEEEECCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCHH
YLWEEATPDGPLRRVFTGDALLIDGCGRTDFQSGDAGTLYDSLTRKLFALPDETLVFPAH
HHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
DYKGRTSSTIGQERAHNSRVAGRTRDEFIDMMRNLNLPRPKLIDVAVPANQRLGLRDGES
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
VPHGA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]