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The map label for this gene is ycbL [H]

Identifier: 73542951

GI number: 73542951

Start: 3577952

End: 3578602

Strand: Direct

Name: ycbL [H]

Synonym: Reut_A3268

Alternate gene names: 73542951

Gene position: 3577952-3578602 (Clockwise)

Preceding gene: 73542949

Following gene: 73542952

Centisome position: 94.0

GC content: 65.9

Gene sequence:

>651_bases
ATGAAAGCCCTGCTGATCCCCGTCACGCCCTTCCAGCAAAACTGTTCGCTGCTGATCGACGAGCACACCGGCAAGGCCGC
CGTTTGCGATCCCGGCGGTGACCTGGACCGCATCCTGGAGGCCGTGAAGGAACAGGGTGTGACGCTGGAAAAGATCTTCC
TCACGCATGGCCATGTCGACCATTGCGCGGGCGCCGCGGCGCTGTCGCGGCAACTCGGCATTCCGATCGAAGGTCCGCAC
GAGGACGAACGCTTCTGGATCGACCAGCTTCCCGAGCAAACCCGCCGCTTCGGCTTCGGCCAGGCCGAAGTGTTCGAACC
CCAGCGCTGGTTGCAGGACGGTGATACGGTCCAGTTCGGCGGCGAGACGCTCGAGGTCTACCATTGCCCCGGCCACACGC
CCGGCCACGTGGTGTTCTTCTCGCGCGCCAACCGGCTCGCCGTGGTCGGCGACGTGCTGTTCGCCGGCTCGATCGGCCGC
ACGGACTTTCCGCGCGGCAATCATGCGGACCTGGTCCGCTCGATCCGCACGCGCCTGTGGCCGTTGGGCGAGGACGTGAC
CTTCATTCCGGGCCACGGCCCGGTATCCACATTCGGCGAAGAGCGTCGCAACAACCCGTTCGTGGCCGATCACCTCATCG
ACGCAGCCTGA

Upstream 100 bases:

>100_bases
TTTTAGAGCTCGCCGCCGGCCCTTCCGCCTGCCGGCGCTACAATGCCGGCACAACCTGCCGCATGCGACCGAGCCTGTCG
CGGCCCACGAAAAGACACCC

Downstream 100 bases:

>100_bases
ACCACAGGCCGTTTCCGCAAGCGCCATGGCAAAGCGGCAAGCTCCCGACACCCGCCCGGAGATCTACGTCAGCACCGACA
TCGAGGCTGACGGACCGATT

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKALLIPVTPFQQNCSLLIDEHTGKAAVCDPGGDLDRILEAVKEQGVTLEKIFLTHGHVDHCAGAAALSRQLGIPIEGPH
EDERFWIDQLPEQTRRFGFGQAEVFEPQRWLQDGDTVQFGGETLEVYHCPGHTPGHVVFFSRANRLAVVGDVLFAGSIGR
TDFPRGNHADLVRSIRTRLWPLGEDVTFIPGHGPVSTFGEERRNNPFVADHLIDAA

Sequences:

>Translated_216_residues
MKALLIPVTPFQQNCSLLIDEHTGKAAVCDPGGDLDRILEAVKEQGVTLEKIFLTHGHVDHCAGAAALSRQLGIPIEGPH
EDERFWIDQLPEQTRRFGFGQAEVFEPQRWLQDGDTVQFGGETLEVYHCPGHTPGHVVFFSRANRLAVVGDVLFAGSIGR
TDFPRGNHADLVRSIRTRLWPLGEDVTFIPGHGPVSTFGEERRNNPFVADHLIDAA
>Mature_216_residues
MKALLIPVTPFQQNCSLLIDEHTGKAAVCDPGGDLDRILEAVKEQGVTLEKIFLTHGHVDHCAGAAALSRQLGIPIEGPH
EDERFWIDQLPEQTRRFGFGQAEVFEPQRWLQDGDTVQFGGETLEVYHCPGHTPGHVVFFSRANRLAVVGDVLFAGSIGR
TDFPRGNHADLVRSIRTRLWPLGEDVTFIPGHGPVSTFGEERRNNPFVADHLIDAA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=195, Percent_Identity=31.2820512820513, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=52.3584905660377, Blast_Score=246, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17538952, Length=189, Percent_Identity=29.1005291005291, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23848; Mature: 23848

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLIPVTPFQQNCSLLIDEHTGKAAVCDPGGDLDRILEAVKEQGVTLEKIFLTHGHVD
CCEEEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHH
HCAGAAALSRQLGIPIEGPHEDERFWIDQLPEQTRRFGFGQAEVFEPQRWLQDGDTVQFG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEECHHHHHCCCCEEEEC
GETLEVYHCPGHTPGHVVFFSRANRLAVVGDVLFAGSIGRTDFPRGNHADLVRSIRTRLW
CCEEEEEECCCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGEDVTFIPGHGPVSTFGEERRNNPFVADHLIDAA
CCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MKALLIPVTPFQQNCSLLIDEHTGKAAVCDPGGDLDRILEAVKEQGVTLEKIFLTHGHVD
CCEEEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCHH
HCAGAAALSRQLGIPIEGPHEDERFWIDQLPEQTRRFGFGQAEVFEPQRWLQDGDTVQFG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHEECHHHHHCCCCEEEEC
GETLEVYHCPGHTPGHVVFFSRANRLAVVGDVLFAGSIGRTDFPRGNHADLVRSIRTRLW
CCEEEEEECCCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGEDVTFIPGHGPVSTFGEERRNNPFVADHLIDAA
CCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]