| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is mrcA [H]
Identifier: 73542820
GI number: 73542820
Start: 3446457
End: 3448832
Strand: Direct
Name: mrcA [H]
Synonym: Reut_A3136
Alternate gene names: 73542820
Gene position: 3446457-3448832 (Clockwise)
Preceding gene: 73542808
Following gene: 73542822
Centisome position: 90.54
GC content: 65.87
Gene sequence:
>2376_bases ATGGCCACAGCACAACCGAAGCCGTCCCTCCCAGCCCGCCGCTCGCTCTGGGCGCGCATCACGTTCTGGGTAGTGGGGCT GATCGTCGCCGGCATCGTGGCGGTCGCGCTGCTGCTCGGCTACGCGCTGCTCGTGGCCGCGCCAAACCTGCCGTCGCTGG ACACCATCACGGACTATCGCCCGAAGATCCCGCTGCGCATCTTCACTGCTGACAATGTCCTGATCGGCGAGTTCGGTGAA GAGCGCCGCAACTTCGTGCCGATCGCGGAGATTCCCGACGTCATGAAGAAGGCGGTGCTGGCGATCGAAGACGACCGCTT CTACGAGCACGGCGGCGTCGACTTCGTCGGCGTGATGCGCGCGGGCCTGGCGAACCTGCGCGGCGGGCTGTCGCAGGGCG CATCCACGATCACCATGCAGGTCGCGCGCAACTTCTTCCTGTCCAGCGAGAAGACCTACACGCGCAAGATCTACGAAATG ATGCTCGCGTACAAGATCGAGGCGAACCTGAGCAAGGACCAGATCCTCGAGCTGTACATGAACCAGATCTACCTGGGCCA GCGCGCCTATGGCTTCGATAGTGCCGCGCGCGTCTACTTCGGCAAGTCCGTGCGCGACGTGACGCCGGCCGAAGCGGCCA TGCTGGCCGGCCTGCCCAAGGCGCCGTCGGCGTACAACCCGGTGGTGAACCCGCGCCGTGCCAAAGTCCGCCAGGAATAC ATCCTGCAGCGCATGCGCGACCTGCGCTACATCACGCCGGAACAATACGACGCCGCCCTCCGCGAAGCCCCGAAGGTGCG CAGCGAGGGCAACGAGTTCTCCACGCACGCGGAGTACGTGGCGGAAATCGTGCGCCAGCTGATGTACGCGCAATACCGCG AGGAAACCTACACGCGTGGCCTGACGGTCTACACCACGCTGACCAAGCCTGACCAGGACGCTGCCTACGAGGCCGTGCGC TCGGGCATCATGAACTACGAGCGCAAGCACGGCTATCGCGGCCCGGAAGCGTTCATCGACCTGCCGTCCGACCAGGCCGA ACGCGAACAGGCTATCGACGATGCACTCGTCGAACATCCCGGCAGCGACGACCTGCGCTCGGCCGTGGTGACCACCGTGT CGCCACGCCAGGTGAAGGCCACGCTGCTGTCCGGCGAAGTGGCCACGATCGAAGGATCGGCGCTGCGTTTCATTGCCCCG TCGCTGTCGGCCAACGCCCAGCCCAAGACCAAGATCCGCCCCGGCGCGATTATCCGCGTGACGCAGGACGACAAGGGCGA CTGGACGGTCACCCAGTTGCCAGAAGTGTCGGCGGCGTTTGTCTCGATCAACCCGCAGGATGGCGAGATCCGCTCGATGG TCGGGGGCTTTGACTTCAACCGCAACAAGTTCAACCACGTGACGCAGGCCTGGCGCCAGCCCGGTTCCAGCTTCAAGCCG TTCATCTACTCGGCAGCGCTGGAAAAAGGCTTCTCGCCGGCCACCGTGATCAATGATGCGCCGCTGACGATCGGCCCGGA CACCGGCGGCCAAGTGTGGGAGCCGAAGAACTACGACGGCAAGTTCGAGGGCCCGATGACCATGCGCCGCGCGCTGGCCA AGTCGAAGAACCTGGTCTCGGTGCGCATCCTGCGGGCAATCGGTACGCAGTACGCGCAGGACTACATCACTCGCTTCGGC TTCGAGGCGGAGAAGCACCCCGCCTACCTGCCGATGGCGCTGGGCGCCGGTAGCGTCACGCCGCTGCAGATGGCCGGCGC CTATTCGGTGTTCGCCAACGGCGGCTACCGCATCAACCCGTACCTGATCCAGAAGGTTGTCGATGCGCGCGGCAAGGTGC TTTCCGAAACCCAGCCGCAGCGCGCCGGCAGCGACGCCGTGCGCGTGCTCGACGCACGCACGGCGTTTATCGCCGACACC ATGTTGCGCGATGTGGTGCGCATGGGGACGGCCAACCCCGCCAAGCAGCGCCTGGGCCGCAATGACCTGGCCGGCAAGAC CGGTACCACCAACGATGCCGTCGATGCGTGGTTCGCGGGCTACACGCCCAACCTGGTTGCGATCGCCTGGATGGGTTACG ACCAGCCCAAGAGCCTGGGCGTGCGCGAGACCGGCGGCGGACTGGCCCTGCCGATCTGGGTTGGCTACATGGGCAAGATG CTCAAGGGCGTGCCGGAAAGCCCGGAACGGCCCGCACCGGAAGGCGTGGTCATGGCCGGCGGCGACTGGACCTTCGAAGA GAACGCGAGCGGCGCTGGCGTGGCATCGGTCGGCCTGGGCGACCCGTGGCCGGGCAAGCCGGAAGAAAGCACGCGTCCGC CAGCCGATGTGGAAGCGGAGAAAAAGAAGATCCTGGAAATGTTCGGCGGGGGCTGA
Upstream 100 bases:
>100_bases TCTTGTAACAGCGCGGTAGCGTCGGGGCCGCCACTGCACGGGGAGTAGCCGCTATACCGGAAGATATAATCCCCCGCACT CCTGACTAGGTTTTTCCCTT
Downstream 100 bases:
>100_bases ACGTCTCACGGACGCCATGCACACGAAAAAGCCGGCCTGCTTGGGCCGGCTTTTTCATTGGTCAGCGCCGGATGGGACGT TGCTCAGCCCAGCTTGAGCG
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 791; Mature: 790
Protein sequence:
>791_residues MATAQPKPSLPARRSLWARITFWVVGLIVAGIVAVALLLGYALLVAAPNLPSLDTITDYRPKIPLRIFTADNVLIGEFGE ERRNFVPIAEIPDVMKKAVLAIEDDRFYEHGGVDFVGVMRAGLANLRGGLSQGASTITMQVARNFFLSSEKTYTRKIYEM MLAYKIEANLSKDQILELYMNQIYLGQRAYGFDSAARVYFGKSVRDVTPAEAAMLAGLPKAPSAYNPVVNPRRAKVRQEY ILQRMRDLRYITPEQYDAALREAPKVRSEGNEFSTHAEYVAEIVRQLMYAQYREETYTRGLTVYTTLTKPDQDAAYEAVR SGIMNYERKHGYRGPEAFIDLPSDQAEREQAIDDALVEHPGSDDLRSAVVTTVSPRQVKATLLSGEVATIEGSALRFIAP SLSANAQPKTKIRPGAIIRVTQDDKGDWTVTQLPEVSAAFVSINPQDGEIRSMVGGFDFNRNKFNHVTQAWRQPGSSFKP FIYSAALEKGFSPATVINDAPLTIGPDTGGQVWEPKNYDGKFEGPMTMRRALAKSKNLVSVRILRAIGTQYAQDYITRFG FEAEKHPAYLPMALGAGSVTPLQMAGAYSVFANGGYRINPYLIQKVVDARGKVLSETQPQRAGSDAVRVLDARTAFIADT MLRDVVRMGTANPAKQRLGRNDLAGKTGTTNDAVDAWFAGYTPNLVAIAWMGYDQPKSLGVRETGGGLALPIWVGYMGKM LKGVPESPERPAPEGVVMAGGDWTFEENASGAGVASVGLGDPWPGKPEESTRPPADVEAEKKKILEMFGGG
Sequences:
>Translated_791_residues MATAQPKPSLPARRSLWARITFWVVGLIVAGIVAVALLLGYALLVAAPNLPSLDTITDYRPKIPLRIFTADNVLIGEFGE ERRNFVPIAEIPDVMKKAVLAIEDDRFYEHGGVDFVGVMRAGLANLRGGLSQGASTITMQVARNFFLSSEKTYTRKIYEM MLAYKIEANLSKDQILELYMNQIYLGQRAYGFDSAARVYFGKSVRDVTPAEAAMLAGLPKAPSAYNPVVNPRRAKVRQEY ILQRMRDLRYITPEQYDAALREAPKVRSEGNEFSTHAEYVAEIVRQLMYAQYREETYTRGLTVYTTLTKPDQDAAYEAVR SGIMNYERKHGYRGPEAFIDLPSDQAEREQAIDDALVEHPGSDDLRSAVVTTVSPRQVKATLLSGEVATIEGSALRFIAP SLSANAQPKTKIRPGAIIRVTQDDKGDWTVTQLPEVSAAFVSINPQDGEIRSMVGGFDFNRNKFNHVTQAWRQPGSSFKP FIYSAALEKGFSPATVINDAPLTIGPDTGGQVWEPKNYDGKFEGPMTMRRALAKSKNLVSVRILRAIGTQYAQDYITRFG FEAEKHPAYLPMALGAGSVTPLQMAGAYSVFANGGYRINPYLIQKVVDARGKVLSETQPQRAGSDAVRVLDARTAFIADT MLRDVVRMGTANPAKQRLGRNDLAGKTGTTNDAVDAWFAGYTPNLVAIAWMGYDQPKSLGVRETGGGLALPIWVGYMGKM LKGVPESPERPAPEGVVMAGGDWTFEENASGAGVASVGLGDPWPGKPEESTRPPADVEAEKKKILEMFGGG >Mature_790_residues ATAQPKPSLPARRSLWARITFWVVGLIVAGIVAVALLLGYALLVAAPNLPSLDTITDYRPKIPLRIFTADNVLIGEFGEE RRNFVPIAEIPDVMKKAVLAIEDDRFYEHGGVDFVGVMRAGLANLRGGLSQGASTITMQVARNFFLSSEKTYTRKIYEMM LAYKIEANLSKDQILELYMNQIYLGQRAYGFDSAARVYFGKSVRDVTPAEAAMLAGLPKAPSAYNPVVNPRRAKVRQEYI LQRMRDLRYITPEQYDAALREAPKVRSEGNEFSTHAEYVAEIVRQLMYAQYREETYTRGLTVYTTLTKPDQDAAYEAVRS GIMNYERKHGYRGPEAFIDLPSDQAEREQAIDDALVEHPGSDDLRSAVVTTVSPRQVKATLLSGEVATIEGSALRFIAPS LSANAQPKTKIRPGAIIRVTQDDKGDWTVTQLPEVSAAFVSINPQDGEIRSMVGGFDFNRNKFNHVTQAWRQPGSSFKPF IYSAALEKGFSPATVINDAPLTIGPDTGGQVWEPKNYDGKFEGPMTMRRALAKSKNLVSVRILRAIGTQYAQDYITRFGF EAEKHPAYLPMALGAGSVTPLQMAGAYSVFANGGYRINPYLIQKVVDARGKVLSETQPQRAGSDAVRVLDARTAFIADTM LRDVVRMGTANPAKQRLGRNDLAGKTGTTNDAVDAWFAGYTPNLVAIAWMGYDQPKSLGVRETGGGLALPIWVGYMGKML KGVPESPERPAPEGVVMAGGDWTFEENASGAGVASVGLGDPWPGKPEESTRPPADVEAEKKKILEMFGGG
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=806, Percent_Identity=39.2059553349876, Blast_Score=533, Evalue=1e-152, Organism=Escherichia coli, GI1786343, Length=249, Percent_Identity=38.9558232931727, Blast_Score=154, Evalue=2e-38, Organism=Escherichia coli, GI1788867, Length=161, Percent_Identity=38.5093167701863, Blast_Score=100, Evalue=3e-22, Organism=Escherichia coli, GI1789601, Length=166, Percent_Identity=34.9397590361446, Blast_Score=91, Evalue=2e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 86699; Mature: 86568
Theoretical pI: Translated: 9.04; Mature: 9.04
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MATAQPKPSLPARRSLWARITFWVVGLIVAGIVAVALLLGYALLVAAPNLPSLDTITDYR CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC PKIPLRIFTADNVLIGEFGEERRNFVPIAEIPDVMKKAVLAIEDDRFYEHGGVDFVGVMR CCCCEEEEECCCEEEECCCHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHH AGLANLRGGLSQGASTITMQVARNFFLSSEKTYTRKIYEMMLAYKIEANLSKDQILELYM HHHHHHHCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH NQIYLGQRAYGFDSAARVYFGKSVRDVTPAEAAMLAGLPKAPSAYNPVVNPRRAKVRQEY HHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH ILQRMRDLRYITPEQYDAALREAPKVRSEGNEFSTHAEYVAEIVRQLMYAQYREETYTRG HHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC LTVYTTLTKPDQDAAYEAVRSGIMNYERKHGYRGPEAFIDLPSDQAEREQAIDDALVEHP EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHCCC GSDDLRSAVVTTVSPRQVKATLLSGEVATIEGSALRFIAPSLSANAQPKTKIRPGAIIRV CCHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEE TQDDKGDWTVTQLPEVSAAFVSINPQDGEIRSMVGGFDFNRNKFNHVTQAWRQPGSSFKP EECCCCCEEEEECCCCEEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCH FIYSAALEKGFSPATVINDAPLTIGPDTGGQVWEPKNYDGKFEGPMTMRRALAKSKNLVS HHHHHHHHCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH VRILRAIGTQYAQDYITRFGFEAEKHPAYLPMALGAGSVTPLQMAGAYSVFANGGYRINP HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHCCCEEEEECCCEEECH YLIQKVVDARGKVLSETQPQRAGSDAVRVLDARTAFIADTMLRDVVRMGTANPAKQRLGR HHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC NDLAGKTGTTNDAVDAWFAGYTPNLVAIAWMGYDQPKSLGVRETGGGLALPIWVGYMGKM CCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHCCCEECCCCEEHHHHHHHHHHH LKGVPESPERPAPEGVVMAGGDWTFEENASGAGVASVGLGDPWPGKPEESTRPPADVEAE HHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHH KKKILEMFGGG HHHHHHHHCCC >Mature Secondary Structure ATAQPKPSLPARRSLWARITFWVVGLIVAGIVAVALLLGYALLVAAPNLPSLDTITDYR CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC PKIPLRIFTADNVLIGEFGEERRNFVPIAEIPDVMKKAVLAIEDDRFYEHGGVDFVGVMR CCCCEEEEECCCEEEECCCHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHH AGLANLRGGLSQGASTITMQVARNFFLSSEKTYTRKIYEMMLAYKIEANLSKDQILELYM HHHHHHHCCHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH NQIYLGQRAYGFDSAARVYFGKSVRDVTPAEAAMLAGLPKAPSAYNPVVNPRRAKVRQEY HHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH ILQRMRDLRYITPEQYDAALREAPKVRSEGNEFSTHAEYVAEIVRQLMYAQYREETYTRG HHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC LTVYTTLTKPDQDAAYEAVRSGIMNYERKHGYRGPEAFIDLPSDQAEREQAIDDALVEHP EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHCCC GSDDLRSAVVTTVSPRQVKATLLSGEVATIEGSALRFIAPSLSANAQPKTKIRPGAIIRV CCHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEE TQDDKGDWTVTQLPEVSAAFVSINPQDGEIRSMVGGFDFNRNKFNHVTQAWRQPGSSFKP EECCCCCEEEEECCCCEEEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCH FIYSAALEKGFSPATVINDAPLTIGPDTGGQVWEPKNYDGKFEGPMTMRRALAKSKNLVS HHHHHHHHCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHH VRILRAIGTQYAQDYITRFGFEAEKHPAYLPMALGAGSVTPLQMAGAYSVFANGGYRINP HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHCCCEEEEECCCEEECH YLIQKVVDARGKVLSETQPQRAGSDAVRVLDARTAFIADTMLRDVVRMGTANPAKQRLGR HHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC NDLAGKTGTTNDAVDAWFAGYTPNLVAIAWMGYDQPKSLGVRETGGGLALPIWVGYMGKM CCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHCCCEECCCCEEHHHHHHHHHHH LKGVPESPERPAPEGVVMAGGDWTFEENASGAGVASVGLGDPWPGKPEESTRPPADVEAE HHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHH KKKILEMFGGG HHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA