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The map label for this gene is degQ [H]

Identifier: 73542780

GI number: 73542780

Start: 3407005

End: 3408201

Strand: Direct

Name: degQ [H]

Synonym: Reut_A3096

Alternate gene names: 73542780

Gene position: 3407005-3408201 (Clockwise)

Preceding gene: 73542778

Following gene: 73542808

Centisome position: 89.5

GC content: 64.08

Gene sequence:

>1197_bases
ATGTTGCGGCGCTTTTGGCTGTTCTTTGCCCAGGCTGTCACGGTCGTGCTGGCAGTCTGGTTCGTCGTGGCCACGCTCAA
GCCAGAGTGGCTGCAGAGGGGCCGCGTCGCGGTGCAGTCGGGGTCGCCTATCGTGGCGCTGAAGGAAGTCGTGCCCAACG
TGGCCGGCGCTGCCGCGCAAGCGTCTTACAGCGAAGCTGCGCGGCAAGCCATGCCTGCCGTAGTGAATATCTTTACCAGC
AAGAACGGCTCCCGACGCTCGCCCCATCCGCAGGCTGAGGACCCGTGGTTCCGCTTCTTCTTCGGCGACCGGCTGCCTGA
GCGCCAGGAACCGGTGTCCAGCCTGGGCTCCGGCGTCATCGTCAGTGCCGAGGGTTACATTCTAACCAACCACCATGTGG
TGGACGGCGCCGATGAAATCGAGGTCGCGCTGACCGATGGCCGCAAGGCCAACGCCAAGGTGGTGGGCTCGGACCCTGAA
ACTGATCTGGCGGTTCTGAAGATTTCGCTGAAGGAACTGCCTGCGATCACACTGGGCCGGCTGGAAAACGTCAAGGTGGG
CGACGTGGTGCTGGCGATCGGTAATCCGTTCGGCGTCGGCCAGACCGTGACGATGGGGATCGTCTCCGCACTGGGCCGCA
GCCATCTGGGGATCAACACGTTTGAGAACTTTATCCAGACGGACGCGGCCATCAACCCGGGCAACTCCGGCGGAGCGCTG
GTGGATGCGCAGGGCAATCTGCTCGGCATCAACACGGCGATCTACTCGCGGTCGGGCGGCTCGCTCGGCATCGGCTTCGC
GATTCCGGTCTCGACGGCCAAGCAGGTGATGGAATCGATCATCTCGACGGGCAGCGTGACGCGCGGCTGGATCGGCGTGG
AACCGCAGGACATGACGCCCGAAATCGCGGAATCGTTCGGACTCGACGCCAAGCAAGGCGCGCTGATCGCGGCCGTGGTG
CAAGGCGGCCCGGCTGACAAGGCAGGCGTGAAGCCGGGCGACGTGCTGGCTTCCGTCGATGGGCAGCCCATTACCGATAC
CACCGCACTGCTCAATGCTATTGCCCAGCTCAAGCCCGGCGTGGATATCAAGATGAAGGTGATTCGCCGCGGCAAGCCTG
CCGAGCTGACGGTGACGATTGGCAAACGGCCCCCGCCTCCGCGGCGTTCGCTGCCGTTCGATGATGAAGAACAGTAG

Upstream 100 bases:

>100_bases
GAGGCCATTGGGACAATAGTCCTTGTAGCGGGAAACTTCCAACAGGTCGTTCAAGTACAATTCCAGCTCTTTAGTCTTCA
TTTCTTGCTCAAACTCCAAT

Downstream 100 bases:

>100_bases
GTCCATCTGGTTCCTGATTGCACAACCGAAAAGCCCCGCCCAGCATGGCGGGGTTTTTTGTTGTCCTTCTCCAGCTGCCC
TACTCCTGAACAATTAGGTT

Product: peptidase S1 and S6, chymotrypsin/Hap:PDZ/DHR/GLGF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLRRFWLFFAQAVTVVLAVWFVVATLKPEWLQRGRVAVQSGSPIVALKEVVPNVAGAAAQASYSEAARQAMPAVVNIFTS
KNGSRRSPHPQAEDPWFRFFFGDRLPERQEPVSSLGSGVIVSAEGYILTNHHVVDGADEIEVALTDGRKANAKVVGSDPE
TDLAVLKISLKELPAITLGRLENVKVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGAL
VDAQGNLLGINTAIYSRSGGSLGIGFAIPVSTAKQVMESIISTGSVTRGWIGVEPQDMTPEIAESFGLDAKQGALIAAVV
QGGPADKAGVKPGDVLASVDGQPITDTTALLNAIAQLKPGVDIKMKVIRRGKPAELTVTIGKRPPPPRRSLPFDDEEQ

Sequences:

>Translated_398_residues
MLRRFWLFFAQAVTVVLAVWFVVATLKPEWLQRGRVAVQSGSPIVALKEVVPNVAGAAAQASYSEAARQAMPAVVNIFTS
KNGSRRSPHPQAEDPWFRFFFGDRLPERQEPVSSLGSGVIVSAEGYILTNHHVVDGADEIEVALTDGRKANAKVVGSDPE
TDLAVLKISLKELPAITLGRLENVKVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGAL
VDAQGNLLGINTAIYSRSGGSLGIGFAIPVSTAKQVMESIISTGSVTRGWIGVEPQDMTPEIAESFGLDAKQGALIAAVV
QGGPADKAGVKPGDVLASVDGQPITDTTALLNAIAQLKPGVDIKMKVIRRGKPAELTVTIGKRPPPPRRSLPFDDEEQ
>Mature_398_residues
MLRRFWLFFAQAVTVVLAVWFVVATLKPEWLQRGRVAVQSGSPIVALKEVVPNVAGAAAQASYSEAARQAMPAVVNIFTS
KNGSRRSPHPQAEDPWFRFFFGDRLPERQEPVSSLGSGVIVSAEGYILTNHHVVDGADEIEVALTDGRKANAKVVGSDPE
TDLAVLKISLKELPAITLGRLENVKVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGAL
VDAQGNLLGINTAIYSRSGGSLGIGFAIPVSTAKQVMESIISTGSVTRGWIGVEPQDMTPEIAESFGLDAKQGALIAAVV
QGGPADKAGVKPGDVLASVDGQPITDTTALLNAIAQLKPGVDIKMKVIRRGKPAELTVTIGKRPPPPRRSLPFDDEEQ

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=274, Percent_Identity=35.7664233576642, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI7019477, Length=289, Percent_Identity=37.3702422145329, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4506141, Length=294, Percent_Identity=35.3741496598639, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI22129776, Length=294, Percent_Identity=32.312925170068, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1789629, Length=330, Percent_Identity=44.2424242424242, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1786356, Length=363, Percent_Identity=41.0468319559229, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789630, Length=328, Percent_Identity=43.2926829268293, Blast_Score=237, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24646839, Length=305, Percent_Identity=32.4590163934426, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41921; Mature: 41921

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVVLAVWFVVATLKPEWLQRGRVAVQSGSPIVALKEVVPNVAGAAAQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCEEEHHHHHCHHHHHHHH
ASYSEAARQAMPAVVNIFTSKNGSRRSPHPQAEDPWFRFFFGDRLPERQEPVSSLGSGVI
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEE
VSAEGYILTNHHVVDGADEIEVALTDGRKANAKVVGSDPETDLAVLKISLKELPAITLGR
EECCCEEEECCEEECCCCCEEEEEECCCCCCCEEECCCCCCCEEEEEEEHHHCCCEECCC
LENVKVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGAL
CCCCEECEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEE
VDAQGNLLGINTAIYSRSGGSLGIGFAIPVSTAKQVMESIISTGSVTRGWIGVEPQDMTP
EECCCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCCCH
EIAESFGLDAKQGALIAAVVQGGPADKAGVKPGDVLASVDGQPITDTTALLNAIAQLKPG
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCC
VDIKMKVIRRGKPAELTVTIGKRPPPPRRSLPFDDEEQ
CCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVVLAVWFVVATLKPEWLQRGRVAVQSGSPIVALKEVVPNVAGAAAQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCEEEHHHHHCHHHHHHHH
ASYSEAARQAMPAVVNIFTSKNGSRRSPHPQAEDPWFRFFFGDRLPERQEPVSSLGSGVI
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEE
VSAEGYILTNHHVVDGADEIEVALTDGRKANAKVVGSDPETDLAVLKISLKELPAITLGR
EECCCEEEECCEEECCCCCEEEEEECCCCCCCEEECCCCCCCEEEEEEEHHHCCCEECCC
LENVKVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGAL
CCCCEECEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEE
VDAQGNLLGINTAIYSRSGGSLGIGFAIPVSTAKQVMESIISTGSVTRGWIGVEPQDMTP
EECCCCEEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEECCCCCCCCH
EIAESFGLDAKQGALIAAVVQGGPADKAGVKPGDVLASVDGQPITDTTALLNAIAQLKPG
HHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCC
VDIKMKVIRRGKPAELTVTIGKRPPPPRRSLPFDDEEQ
CCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]